Glial fibrillary acidic protein and glutamine synthetase in subregions of prefrontal cortex in schizophrenia and mood disorder

Neuroscience Letters

Volumn 404, Issue 3, 2006, Pages 276-281

  Toro, Carla T ^a   Hallak, Jaime E C ^a   Dunham, Jason S ^a   Deakin, John F W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Astrocytes; Glutamate; Human brain; Neuropsychiatric disorders

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID;

ADULT; ANTIGEN SPECIFICITY; ARTICLE; AUTORADIOGRAPHY; BIPOLAR DISORDER; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; MENTAL DISEASE; MOOD DISORDER; OPTICAL DENSITY; ORBITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHIZOPHRENIA; STATISTICAL SIGNIFICANCE;

ADULT; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; AUTORADIOGRAPHY; BIPOLAR DISORDER; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE-AMMONIA LIGASE; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOOD DISORDERS; PREFRONTAL CORTEX; SCHIZOPHRENIA;

EID: 33746308910     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.05.067     Document Type: Article

References (38)

1. Diagnostic and Statistical Manual of Mental Disorders IV, fourth ed., American Psychiatric Association, Washington, DC, 1994.
2. Arnold S.E., Franz B.R., Trojanowski J.Q., Moberg P.J., and Gur R.E. Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia. Acta Neuropathol. (Berl) 91 (1996) 269-277
3. Benes F.M., Davidson J., and Bird E.D. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch. Gen. Psychiatry 43 (1986) 31-35
4. Benes F.M., McSparren J., Bird E.D., SanGiovanni J.P., and Vincent S.L. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch. Gen. Psychiatry 48 (1991) 996-1001
5. Berrettini W. Bipolar disorder and schizophrenia: convergent molecular data. Neuromolecular Med. 5 (2004) 109-117
6. Burbaeva G.S., Boksha I.S., Turishcheva M.S., Vorobyeva E.A., Savushkina O.K., and Tereshkina E.B. Glutamine synthetase and glutamate dehydrogenase in the prefrontal cortex of patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 675-680
7. Catalani A., Sabbatini M., Consoli C., Cinque C., Tomassoni D., Azmitia E., Angelucci L., and Amenta F. Glial fibrillary acidic protein immunoreactive astrocytes in developing rat hippocampus. Mech. Ageing Dev. 123 (2002) 481-490
8. Cotter D., Mackay D., Chana G., Beasley C., Landau S., and Everall I.P. Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder. Cereb. Cortex 12 (2002) 386-394
9. Gluck M.R., Thomas R.G., Davis K.L., and Haroutunian V. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am. J. Psychiatry 159 (2002) 1165-1173
10. Hakak Y., Walker J.R., Li C., Wong W.H., Davis K.L., Buxbaum J.D., Haroutunian V., and Fienberg A.A. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 4746-4751
11. Haydon P.G. GLIA: listening and talking to the synapse. Nat. Rev. Neurosci. 2 (2001) 185-193
12. Hertz L., Dringen R., Schousboe A., and Robinson S.R. Astrocytes: glutamate producers for neurons. J. Neurosci. Res. 57 (1999) 417-428
13. Hertz L., and Zielke H.R. Astrocytic control of glutamatergic activity: astrocytes as stars of the show. Trends Neurosci. 27 (2004) 735-743
14. Hof P.R., Haroutunian V., Friedrich Jr. V.L., Byne W., Buitron C., Perl D.P., and Davis K.L. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol. Psychiatry 53 (2003) 1075-1085
15. Hughes E.G., Maguire J.L., McMinn M.T., Scholz R.E., and Sutherland M.L. Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking. Brain Res. Mol. Brain Res. 124 (2004) 114-123
16. Mason C.A., Edmondson J.C., and Hatten M.E. The extending astroglial process: development of glial cell shape, the growing tip, and interactions with neurons. J. Neurosci. 8 (1988) 3124-3134
17. Matute C., Melone M., Vallejo-Illarramendi A., and Conti F. Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics. Glia 49 (2005) 451-455
18. Murray R.M., and Lewis S.W. Is schizophrenia a neurodevelopmental disorder?. Br. Med. J. (Clin. Res. Ed.) 295 (1987) 681-682
19. Ongur D., Drevets W.C., and Price J.L. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 13290-13295
20. Radewicz K., Garey L.J., Gentleman S.M., and Reynolds R. Increase in HLA-DR immunoreactive microglia in frontal and temporal cortex of chronic schizophrenics. J. Neuropathol. Exp. Neurol. 59 (2000) 137-150
21. Rajkowska G., and Goldman-Rakic P.S. Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I. Remapping of areas 9 and 46 using quantitative criteria. Cereb. Cortex 5 (1995) 307-322
22. Rajkowska G., Halaris A., and Selemon L.D. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biol. Psychiatry 49 (2001) 741-752
23. Rajkowska G., Miguel-Hidalgo J., Makkos Z., Meltzer H., Overholser J., and Stockmeier C. Layer-specific reductions in GFAP-reactive astroglia in the dorsolateral prefrontal cortex in schizophrenia. Schizophr. Res. 57 (2002) 127
24. Rajkowska G., Miguel-Hidalgo J.J., Wei J., Dilley G., Pittman S.D., Meltzer H.Y., Overholser J.C., Roth B.L., and Stockmeier C.A. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol. Psychiatry 45 (1999) 1085-1098
25. Roberts G.W., Colter N., Lofthouse R., Bogerts B., Zech M., and Crow T.J. Gliosis in schizophrenia: a survey. Biol. Psychiatry 21 (1986) 1043-1050
26. Roberts G.W., Leigh P.N., and Weinberger D.R. Neuropsychiatric Disorders (1993), Wolfe Publishing, Oxford
27. Robinson S.R. Neuronal expression of glutamine synthetase in Alzheimer's disease indicates a profound impairment of metabolic interactions with astrocytes. Neurochem. Int. 36 (2000) 471-482
28. Selemon L.D., Lidow M.S., and Goldman-Rakic P.S. Increased volume and glial density in primate prefrontal cortex associated with chronic antipsychotic drug exposure. Biol. Psychiatry 46 (1999) 161-172
29. Selemon L.D., Mrzljak J., Kleinman J.E., Herman M.M., and Goldman-Rakic P.S. Regional specificity in the neuropathologic substrates of schizophrenia: a morphometric analysis of Broca's area 44 and area 9. Arch. Gen. Psychiatry 60 (2003) 69-77
30. Selemon L.D., Rajkowska G., and Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch. Gen. Psychiatry 52 (1995) 805-818
31. Selemon L.D., Rajkowska G., and Goldman-Rakic P.S. Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients: application of a three-dimensional, stereologic counting method. J. Comp. Neurol. 392 (1998) 402-412
32. Stevens J.R. Neuropathology of schizophrenia. Arch. Gen. Psychiatry 39 (1982) 1131-1139
33. Stewart D.G., and Davis K.L. Possible contributions of myelin and oligodendrocyte dysfunction to schizophrenia. Int. Rev. Neurobiol. 59 (2004) 381-424
34. Sugai T., Kawamura M., Iritani S., Araki K., Makifuchi T., Imai C., Nakamura R., Kakita A., Takahashi H., and Nawa H. Prefrontal abnormality of schizophrenia revealed by DNA microarray: impact on glial and neurotrophic gene expression. Ann. N.Y. Acad. Sci. 1025 (2004) 84-91
35. Toro C., and Deakin J.F. NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder. Schizophr. Res. 80 (2005) 323-330
36. Torrey E.F., Webster M., Knable M., Johnston N., and Yolken R.H. The Stanley foundation brain collection and neuropathology consortium. Schizophr. Res. 44 (2000) 151-155
37. Weinstein D.E., Shelanski M.L., and Liem R.K. Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons. J. Cell Biol. 112 (1991) 1205-1213
38. Wierzba-Bobrowicz T., Lewandowska E., Kosno-Kruszewska E., Lechowicz W., Pasennik E., and Schmidt-Sidor B. Degeneration of microglial cells in frontal and temporal lobes of chronic schizophrenics. Folia Neuropathol. 42 (2004) 157-165