메뉴 건너뛰기




Volumn 9, Issue 3, 2006, Pages 257-262

Evaluation of intestinal trophism: Review of current methods and techniques

Author keywords

Apoptosis; Colon; Immunohistochemistry; Intestine; Mucosa; Proliferation

Indexed keywords

BROXURIDINE; CYCLINE; HISTONE; KI 67 ANTIGEN; MESSENGER RNA; THYMIDINE;

EID: 33746228297     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/01.mco.0000222108.15548.11     Document Type: Review
Times cited : (6)

References (65)
  • 1
    • 18044384221 scopus 로고    scopus 로고
    • Twists and turns in the development and maintenance of the mammalian small intestine epithelium
    • Hauck HL, Swanson KS, Kenis PJA, et al. Twists and turns in the development and maintenance of the mammalian small intestine epithelium. Birth Defects Res C Embryo Today 2005; 75:58-71. This is an excellent review focusing on the multiple signaling pathways to intestinal epithelial proliferation and differentiation.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 58-71
    • Hauck, H.L.1    Swanson, K.S.2    Kenis, P.J.A.3
  • 2
    • 0141831741 scopus 로고    scopus 로고
    • Mucosal repair in the gastrointestinal tract
    • Mammen JM, Matthews JB. Mucosal repair in the gastrointestinal tract. Crit Care Med 2003; 31 (8 Suppl):S532-S537.
    • (2003) Crit Care Med , vol.31 , Issue.8 SUPPL.
    • Mammen, J.M.1    Matthews, J.B.2
  • 3
    • 19544375032 scopus 로고    scopus 로고
    • Wnt control of stem cells and differentiation in the intestinal epithelium
    • Pinto D, Clevers H. Wnt control of stem cells and differentiation in the intestinal epithelium. Exp Cell Res 2005; 306:357-363. This outstanding review discusses the recent advances related to the Wnt/β-catenin signaling pathway in regulating intestinal stem cells.
    • (2005) Exp Cell Res , vol.306 , pp. 357-363
    • Pinto, D.1    Clevers, H.2
  • 4
    • 0028589378 scopus 로고
    • Regulation of the cell number in mammalian gastrointestinal tract: The importance of apoptosis
    • Hall PA, Coates PJ, Ansari B, Hopwood D. Regulation of the cell number in mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 1994; 107:3569-3577.
    • (1994) J Cell Sci , vol.107 , pp. 3569-3577
    • Hall, P.A.1    Coates, P.J.2    Ansari, B.3    Hopwood, D.4
  • 5
    • 0033825287 scopus 로고    scopus 로고
    • An evaluation of methods for grading histologic injury following ischemia/reperfusion of the small bowel
    • Quaedackers JSLT, Beuk RJ, Bennet L, et al. An evaluation of methods for grading histologic injury following ischemia/reperfusion of the small bowel. Transplant Proc 2000; 32:1307-1310.
    • (2000) Transplant Proc , vol.32 , pp. 1307-1310
    • Quaedackers, J.S.L.T.1    Beuk, R.J.2    Bennet, L.3
  • 6
    • 19044374851 scopus 로고    scopus 로고
    • Influence of pneumoperitoneum on small bowel anastomoses: A histological analysis in the rat model
    • Rosch R, Stumpf M, Junge K, et al. Influence of pneumoperitoneum on small bowel anastomoses: a histological analysis in the rat model. J Invest Surg 2005; 18:63-69. This paper demonstrates that pneumoperitoneum is not associated with intestinal ischemia.
    • (2005) J Invest Surg , vol.18 , pp. 63-69
    • Rosch, R.1    Stumpf, M.2    Junge, K.3
  • 7
    • 11244349716 scopus 로고    scopus 로고
    • Impact of vasoactive intestinal polypeptide and gastrin-releasing peptide on small bowel microcirculation and mucosal injury after hepatic ischemia/reperfusion in rats
    • Leister I, Sydow J, Stojanovic T, et al. Impact of vasoactive intestinal polypeptide and gastrin-releasing peptide on small bowel microcirculation and mucosal injury after hepatic ischemia/reperfusion in rats. Int J Colorectal Dis 2005; 20:42-48.
    • (2005) Int J Colorectal Dis , vol.20 , pp. 42-48
    • Leister, I.1    Sydow, J.2    Stojanovic, T.3
  • 8
    • 24144447669 scopus 로고    scopus 로고
    • Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats
    • Hei ZQ, Huang HQ, Zhang JJ, et al. Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats. World J Gastroenterol 2005; 28:4986-4991.
    • (2005) World J Gastroenterol , vol.28 , pp. 4986-4991
    • Hei, Z.Q.1    Huang, H.Q.2    Zhang, J.J.3
  • 9
    • 23944510183 scopus 로고    scopus 로고
    • Beneficial effects of oral insulin on intestinal recovery following ischemia-reperfusion injury in rat
    • Sukhotnik I, Shehadeh N, Mogilner J, et al. Beneficial effects of oral insulin on intestinal recovery following ischemia-reperfusion injury in rat. J Surg Res 2005; 128:108-113. A very well designed experiment comprising histology, cell proliferation and apoptosis techniques to assess gut trophism.
    • (2005) J Surg Res , vol.128 , pp. 108-113
    • Sukhotnik, I.1    Shehadeh, N.2    Mogilner, J.3
  • 10
    • 0014864255 scopus 로고
    • Intestinal mucosal lesion in low-flow states
    • Chiu C, McArdle AH, Brown R, et al. Intestinal mucosal lesion in low-flow states. Arch Surg 1970; 101:478-483.
    • (1970) Arch Surg , vol.101 , pp. 478-483
    • Chiu, C.1    McArdle, A.H.2    Brown, R.3
  • 11
    • 0025218706 scopus 로고
    • The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion
    • Park PO, Haglund U, Bulkley GB, Falt K. The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion. Surgery 1990; 107:574-580.
    • (1990) Surgery , vol.107 , pp. 574-580
    • Park, P.O.1    Haglund, U.2    Bulkley, G.B.3    Falt, K.4
  • 12
    • 21544443482 scopus 로고    scopus 로고
    • Parenteral arginine impairs intestinal adaptation following massive small bowel resection in a rat model
    • Sukhotnik I, Mogilner JG, Lerner A. Parenteral arginine impairs intestinal adaptation following massive small bowel resection in a rat model. Pediatr Surg Int 2005; 21:460-465. Arginine is implicated in inhibiting gut adaptation following extensive bowel resection.
    • (2005) Pediatr Surg Int , vol.21 , pp. 460-465
    • Sukhotnik, I.1    Mogilner, J.G.2    Lerner, A.3
  • 13
    • 33645881377 scopus 로고    scopus 로고
    • Effects of the combined use of glutamine and growth hormone in the intestinal adaptation after massive resection of the small bowel in rats
    • Spadoni JM, Aguilar-Nascimento JE, Silva MH, et al. Effects of the combined use of glutamine and growth hormone in the intestinal adaptation after massive resection of the small bowel in rats. Acta Cir Bras 2005; 20:382-389.
    • (2005) Acta Cir Bras , vol.20 , pp. 382-389
    • Spadoni, J.M.1    Aguilar-Nascimento, J.E.2    Silva, M.H.3
  • 14
    • 23944490147 scopus 로고    scopus 로고
    • Chronic low intake of protein or vitamins increases the intestinal epithelial cell apoptosis in Wistar/NIN rats
    • Bodiga VL, Boindala S, Putcha U, et al. Chronic low intake of protein or vitamins increases the intestinal epithelial cell apoptosis in Wistar/NIN rats. Nutrition 2005; 21:949-960. An outstanding experimental study. Protein and vitamin restriction are implicated in increased apoptosis, and morphological and functional villi alterations.
    • (2005) Nutrition , vol.21 , pp. 949-960
    • Bodiga, V.L.1    Boindala, S.2    Putcha, U.3
  • 15
    • 33644640616 scopus 로고    scopus 로고
    • Weight loss and morphometric study of intestinal mucosa in rats after massive intestinal resection: Influence of a glutamine-enriched diet
    • Ribeiro SR, Pinto PE Jr, de Miranda AC, et al. Weight loss and morphometric study of intestinal mucosa in rats after massive intestinal resection: influence of a glutamine-enriched diet. Rev Hosp Clin Fac Med Sao Paulo 2004; 59:349-356.
    • (2004) Rev Hosp Clin Fac Med Sao Paulo , vol.59 , pp. 349-356
    • Ribeiro, S.R.1    Pinto Jr., P.E.2    De Miranda, A.C.3
  • 16
    • 21244451602 scopus 로고    scopus 로고
    • Time-course of morphologic changes and peptide YY adaptation in ileal mucosa after loop ileostomy in humans
    • Oh NG, Son GM, Sin JY, et al. Time-course of morphologic changes and peptide YY adaptation in ileal mucosa after loop ileostomy in humans. Dis Colon Rectum 2005; 48:1287-1294. This interesting clinical study showed that the mucosal secretion of peptide YY can be maintained even in the defunctioned bowel.
    • (2005) Dis Colon Rectum , vol.48 , pp. 1287-1294
    • Oh, N.G.1    Son, G.M.2    Sin, J.Y.3
  • 17
    • 9244225221 scopus 로고    scopus 로고
    • Morphological and functional alterations of the intestine of rats with iron-deficiency anemia
    • Wayhs ML, Patricio FS, Amancio OM, et al. Morphological and functional alterations of the intestine of rats with iron-deficiency anemia. Braz J Med Biol Res 2004; 37:1631-1635.
    • (2004) Braz J Med Biol Res , vol.37 , pp. 1631-1635
    • Wayhs, M.L.1    Patricio, F.S.2    Amancio, O.M.3
  • 18
    • 31544473715 scopus 로고    scopus 로고
    • Insulin-like growth factor-I (IGF-I) attenuates jejunal atrophy in association with increased expression of IGF-I binding protein-5 in parenterally fed mice
    • Murali SG, Nelson DW, Draxler AK, et al. Insulin-like growth factor-I (IGF-I) attenuates jejunal atrophy in association with increased expression of IGF-I binding protein-5 in parenterally fed mice. J Nutr 2005; 135:2553-2559.
    • (2005) J Nutr , vol.135 , pp. 2553-2559
    • Murali, S.G.1    Nelson, D.W.2    Draxler, A.K.3
  • 19
    • 19044399851 scopus 로고    scopus 로고
    • Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice
    • Shin ED, Estall JL, Izzo A, et al. Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice. Gastroenterology 2005; 128:1340-1353. This study concludes that glucagon-like peptide-2 is a regulator of the dynamic adaptation of the intestinal mucosa in the presence of luminal nutrients.
    • (2005) Gastroenterology , vol.128 , pp. 1340-1353
    • Shin, E.D.1    Estall, J.L.2    Izzo, A.3
  • 20
    • 21044441460 scopus 로고    scopus 로고
    • Colostrum protein concentrate enhances intestinal adaptation after massive small bowel resection in juvenile pigs
    • Nagy ES, Paris MC, Taylor RG, et al. Colostrum protein concentrate enhances intestinal adaptation after massive small bowel resection in juvenile pigs. J Pediatr Gastroenterol Nutr 2004; 39:487-492.
    • (2004) J Pediatr Gastroenterol Nutr , vol.39 , pp. 487-492
    • Nagy, E.S.1    Paris, M.C.2    Taylor, R.G.3
  • 21
    • 7444239050 scopus 로고    scopus 로고
    • Ethanol intake inhibits growth of the epithelium in the intestine of pregnant rats
    • Peres WAF, Carmo MGT, Zucoloto S. Ethanol intake inhibits growth of the epithelium in the intestine of pregnant rats. Alcohol 2004; 33:83-89. Peres et al. demonstrate that ethanol ingestion may inhibit gut trophism during pregnancy.
    • (2004) Alcohol , vol.33 , pp. 83-89
    • Peres, W.A.F.1    Carmo, M.G.T.2    Zucoloto, S.3
  • 22
    • 7744245303 scopus 로고    scopus 로고
    • Comparative effects of glucagon-like peptide-2 (GLP-2), growth hormone (GH), and keratinocyte growth factor (KGF) on markers of gut adaptation after massive small bowel resection in rats
    • Washizawa N, Gu LH, Gu L, et al. Comparative effects of glucagon-like peptide-2 (GLP-2), growth hormone (GH), and keratinocyte growth factor (KGF) on markers of gut adaptation after massive small bowel resection in rats. JPEN J Parenter Enteral Nutr 2004; 28:399-409. This study superbly examines the intricacies of the effects of glucagon-like peptide-2, growth hormone, and keratinocyte growth factor in an animal model of short bowel syndrome.
    • (2004) JPEN J Parenter Enteral Nutr , vol.28 , pp. 399-409
    • Washizawa, N.1    Gu, L.H.2    Gu, L.3
  • 23
    • 22644440449 scopus 로고    scopus 로고
    • Longitudinal mechanical tension induces growth in the small bowel of juvenile rats
    • Safford SD, Freemerman AJ, Safford KM. Longitudinal mechanical tension induces growth in the small bowel of juvenile rats. Gut 2005; 54:1085-1090. An interesting study demonstrating that tension induces the increase in length, growth, and enzymatic activity in the small intestine.
    • (2005) Gut , vol.54 , pp. 1085-1090
    • Safford, S.D.1    Freemerman, A.J.2    Safford, K.M.3
  • 24
    • 4544348838 scopus 로고    scopus 로고
    • Probiotics enhance the recovery of gut atrophy in experimental malnutrition
    • Dock-Nascimento DB, Aguilar-Nascimento JE, Latorraca MQ. Probiotics enhance the recovery of gut atrophy in experimental malnutrition. Biocell 2004; 28:143-150.
    • (2004) Biocell , vol.28 , pp. 143-150
    • Dock-Nascimento, D.B.1    Aguilar-Nascimento, J.E.2    Latorraca, M.Q.3
  • 25
    • 23044511566 scopus 로고    scopus 로고
    • Intestinal and systemic effects of oral insulin supplementation in rats after weaning
    • Shamir R, Muslach M, Sukhotnik I. Intestinal and systemic effects of oral insulin supplementation in rats after weaning. Dig Dis Sci 2005; 50:1239-1244.
    • (2005) Dig Dis Sci , vol.50 , pp. 1239-1244
    • Shamir, R.1    Muslach, M.2    Sukhotnik, I.3
  • 26
    • 12844277128 scopus 로고    scopus 로고
    • Genistein inhibits intestinal cell proliferation in piglets
    • Chen AC, Berhow MA, Tappenden KA, Donovan SM. Genistein inhibits intestinal cell proliferation in piglets. Pediatr Res 2005; 57:192-200. A well designed experiment to assess cell dynamics in intestinal mucosa.
    • (2005) Pediatr Res , vol.57 , pp. 192-200
    • Chen, A.C.1    Berhow, M.A.2    Tappenden, K.A.3    Donovan, S.M.4
  • 27
    • 33644877338 scopus 로고    scopus 로고
    • Dietary supplementation with orotate and uracil increases adaptive growth of jejunal mucosa after massive small bowel resection in rats
    • Evans ME, Tian J, Gu LH, et al. Dietary supplementation with orotate and uracil increases adaptive growth of jejunal mucosa after massive small bowel resection in rats. JPEN J Parenter Enteral Nutr 2005; 29:315-320.
    • (2005) JPEN J Parenter Enteral Nutr , vol.29 , pp. 315-320
    • Evans, M.E.1    Tian, J.2    Gu, L.H.3
  • 28
    • 13844316807 scopus 로고    scopus 로고
    • Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome
    • Martin GR, Wallace LE, Hartmann B, et al. Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2005; 288:G431-G438.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Martin, G.R.1    Wallace, L.E.2    Hartmann, B.3
  • 29
    • 0018975884 scopus 로고
    • The metaphase arrest: A critical review
    • Wright NA, Appleton DR. The metaphase arrest: a critical review. Cell Tissue Kinet 1980; 3:643-663.
    • (1980) Cell Tissue Kinet , vol.3 , pp. 643-663
    • Wright, N.A.1    Appleton, D.R.2
  • 30
    • 0035001788 scopus 로고    scopus 로고
    • Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats
    • Berlanga-Acosta J, Playford RJ, Mandir N, Goodlad RA. Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats. Gut 2001; 48:803-807.
    • (2001) Gut , vol.48 , pp. 803-807
    • Berlanga-Acosta, J.1    Playford, R.J.2    Mandir, N.3    Goodlad, R.A.4
  • 31
    • 0031694491 scopus 로고    scopus 로고
    • Cell proliferation and its evaluation in the colonic mucosa: Effect of ethanol
    • Seitz HK, Simanowski UA, Homann N, Waldherr R. Cell proliferation and its evaluation in the colonic mucosa: effect of ethanol. Z Gastroenterol 1998; 36:645-655.
    • (1998) Z Gastroenterol , vol.36 , pp. 645-655
    • Seitz, H.K.1    Simanowski, U.A.2    Homann, N.3    Waldherr, R.4
  • 32
    • 21244445701 scopus 로고    scopus 로고
    • Circadian variation of the cell proliferation in the jejunum epithelium of rats at weaning phase
    • Gomes JR, Pereira AAM, Barth JS, et al. Circadian variation of the cell proliferation in the jejunum epithelium of rats at weaning phase. Cell Prolif 2005; 38:147-152.
    • (2005) Cell Prolif , vol.38 , pp. 147-152
    • Gomes, J.R.1    Aam, P.2    Barth, J.S.3
  • 33
    • 10244227977 scopus 로고    scopus 로고
    • Characteristic expression of gamma-aminobutyric acid and glutamate decarboxylase in rat jejunum and its relation to differentiation of epithelial cells
    • Wang FY, Watanabe M, Zhu RM, Maemura K. Characteristic expression of gamma-aminobutyric acid and glutamate decarboxylase in rat jejunum and its relation to differentiation of epithelial cells. World J Gastroenterol 2004; 10:3608-3611.
    • (2004) World J Gastroenterol , vol.10 , pp. 3608-3611
    • Wang, F.Y.1    Watanabe, M.2    Zhu, R.M.3    Maemura, K.4
  • 34
    • 26444433211 scopus 로고    scopus 로고
    • Interleukin-17 is a potent immunomodulator and regulator of normal human intestinal epithelial cell growth
    • Schwartz S, Beaulieu JF, Ruemmele FM. Interleukin-17 is a potent immunomodulator and regulator of normal human intestinal epithelial cell growth. Biochem Biophys Res Commun 2005; 337:505-509. This outstanding study has shown that IL-17 is a potent inhibitor of intestinal epithelial cell proliferation.
    • (2005) Biochem Biophys Res Commun , vol.337 , pp. 505-509
    • Schwartz, S.1    Beaulieu, J.F.2    Ruemmele, F.M.3
  • 35
    • 19544385971 scopus 로고    scopus 로고
    • Reparative properties of a commercial fish protein hydrolysate preparation
    • Fitzgerald AJ, Rai PS, Marchbank T, et al. Reparative properties of a commercial fish protein hydrolysate preparation. Gut 2005; 54:775-781.
    • (2005) Gut , vol.54 , pp. 775-781
    • Fitzgerald, A.J.1    Rai, P.S.2    Marchbank, T.3
  • 36
    • 0037108679 scopus 로고    scopus 로고
    • Assessment of proliferation in vivo using 2-[(11)C] thymidine positron emission tomography in advanced intra-abdominal malignancies
    • Wells P, Gunn RN, Alison M, et al. Assessment of proliferation in vivo using 2-[(11)C] thymidine positron emission tomography in advanced intra-abdominal malignancies. Cancer Res 2002; 62:5698-5702.
    • (2002) Cancer Res , vol.62 , pp. 5698-5702
    • Wells, P.1    Gunn, R.N.2    Alison, M.3
  • 37
    • 9944248171 scopus 로고    scopus 로고
    • Measuring tumor pharmacodynamic response using PET proliferation probes: The case for 2-[(11)C]-thymidine
    • Well P, West C, Jones T, et al. Measuring tumor pharmacodynamic response using PET proliferation probes: the case for 2-[(11)C]-thymidine. Biochim Biophys Acta 2004; 1705:91-102.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 91-102
    • Well, P.1    West, C.2    Jones, T.3
  • 38
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo and 5-iodo-deoxyuridine: A new reagent for detection of DNA replication
    • Gratzner HG. Monoclonal antibody to 5-bromo and 5-iodo-deoxyuridine: a new reagent for detection of DNA replication. Science 1982; 218:474-475.
    • (1982) Science , vol.218 , pp. 474-475
    • Gratzner, H.G.1
  • 39
    • 1542724588 scopus 로고    scopus 로고
    • A short history of the initial application of anti-5-BrdU to the detection and measurement of S phase
    • Leif RC, Stein JH, Zucker RM. A short history of the initial application of anti-5-BrdU to the detection and measurement of S phase. Cytometry A 2004; 58:45-52. An exceptional historical review of the development of the BrdU method to detect cell proliferation.
    • (2004) Cytometry A , vol.58 , pp. 45-52
    • Leif, R.C.1    Stein, J.H.2    Zucker, R.M.3
  • 40
    • 0344862102 scopus 로고    scopus 로고
    • Evaluation of cell proliferation in rat tissue with BrdU, PNCA, Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA
    • Muskhelishvili L, Latendresse JR, Kodell RL, Henderson EB. Evaluation of cell proliferation in rat tissue with BrdU, PNCA, Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA. J Histochem Cytochem 2003; 51:1681-1688.
    • (2003) J Histochem Cytochem , vol.51 , pp. 1681-1688
    • Muskhelishvili, L.1    Latendresse, J.R.2    Kodell, R.L.3    Henderson, E.B.4
  • 41
    • 24344462304 scopus 로고    scopus 로고
    • Opposing roles for p21 (waf1/cip1) and p27(kip1) in enterocyte differentiation, proliferation, and migration
    • Stehr W, Mercer TI, Bernal NP, et al. Opposing roles for p21 (waf1/cip1) and p27(kip1) in enterocyte differentiation, proliferation, and migration. Surgery 2005; 138:187-194.
    • (2005) Surgery , vol.138 , pp. 187-194
    • Stehr, W.1    Mercer, T.I.2    Bernal, N.P.3
  • 42
    • 12544251114 scopus 로고    scopus 로고
    • Impaired intestinal cell proliferation and cell death in leptin-deficient obese mice
    • Kiely JM, Noh JH, Pitt HA, Swartz-Basile DA. Impaired intestinal cell proliferation and cell death in leptin-deficient obese mice. JPEN J Parenter Enteral Nutr 2005; 29:30-35. This excellent experimental study demonstrates that leptin deficiency impairs both cell proliferation and apoptosis after small bowel transection or resection.
    • (2005) JPEN J Parenter Enteral Nutr , vol.29 , pp. 30-35
    • Kiely, J.M.1    Noh, J.H.2    Pitt, H.A.3    Swartz-Basile, D.A.4
  • 43
    • 16344390597 scopus 로고    scopus 로고
    • Effect of subcutaneous insulin on intestinal adaptation in a rat model of short bowel syndrome
    • Sukhotnik I, Mogilner JG, Shamir R, et al. Effect of subcutaneous insulin on intestinal adaptation in a rat model of short bowel syndrome. Pediatr Surg Int 2005; 21:132-137.
    • (2005) Pediatr Surg Int , vol.21 , pp. 132-137
    • Sukhotnik, I.1    Mogilner, J.G.2    Shamir, R.3
  • 44
    • 0001298056 scopus 로고    scopus 로고
    • PCNA binding proteins
    • Tsurimoto T. PCNA binding proteins. Front Biosci 1999; 4:d849-d858.
    • (1999) Front Biosci , vol.4
    • Tsurimoto, T.1
  • 45
    • 0035027432 scopus 로고    scopus 로고
    • Epithelial proliferation and ras p21 oncoprotein expression in rectal mucosa of patients with ulcerative colitis
    • Ierardi E, Principi M, Francavilla R, et al. Epithelial proliferation and ras p21 oncoprotein expression in rectal mucosa of patients with ulcerative colitis. Dig Dis Sci 2001; 46:1083-1087.
    • (2001) Dig Dis Sci , vol.46 , pp. 1083-1087
    • Ierardi, E.1    Principi, M.2    Francavilla, R.3
  • 46
    • 20444451970 scopus 로고    scopus 로고
    • Epithelial cell proliferation of the colonic mucosa in diverticular disease: A case-control study
    • Morini S, Hassan C, Zullo A, et al. Epithelial cell proliferation of the colonic mucosa in diverticular disease: a case-control study. Aliment Pharmacol Ther 2005; 21:1385-1390. This clinical study provides good information on the mucosal cell proliferation status in patients with diverticular disease.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 1385-1390
    • Morini, S.1    Hassan, C.2    Zullo, A.3
  • 47
    • 7244227682 scopus 로고    scopus 로고
    • Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel
    • Langlands SJ, Hopkins MJ, Coleman N, Cummings JH. Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel. Gut 2004; 53:1610-1616. This interesting clinical study discloses the importance of prebiotic carbohydrates in colonic flora.
    • (2004) Gut , vol.53 , pp. 1610-1616
    • Langlands, S.J.1    Hopkins, M.J.2    Coleman, N.3    Cummings, J.H.4
  • 48
    • 26944478974 scopus 로고    scopus 로고
    • Serum bile acids, programmed cell death and cell proliferation in the mucosa of patients with colorectal adenomas
    • Fracchia M, Galatola G, Sarotto M, et al. Serum bile acids, programmed cell death and cell proliferation in the mucosa of patients with colorectal adenomas. Dig Liver Dis 2005; 37:509-514.
    • (2005) Dig Liver Dis , vol.37 , pp. 509-514
    • Fracchia, M.1    Galatola, G.2    Sarotto, M.3
  • 49
    • 33646559572 scopus 로고    scopus 로고
    • Effects of different phytosterol analogs on colonic mucosal cell proliferation in hamsters
    • 26 September [Epub ahead of print]
    • Jia X, Ebine N, Wang Y, et al. Effects of different phytosterol analogs on colonic mucosal cell proliferation in hamsters. J Nutr Biochem; 26 September [Epub ahead of print].
    • J Nutr Biochem
    • Jia, X.1    Ebine, N.2    Wang, Y.3
  • 50
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 51
    • 0023158779 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of radiosensitivity
    • Carmichael J, DeGraff WG, Gazdar AF, et al. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res 1987; 47:943-946.
    • (1987) Cancer Res , vol.47 , pp. 943-946
    • Carmichael, J.1    DeGraff, W.G.2    Gazdar, A.F.3
  • 52
    • 0032801428 scopus 로고    scopus 로고
    • Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid
    • Sturm A, Sudermann T, Schulte KM, et al. Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid. Gastroenterology 1999; 117:368-377.
    • (1999) Gastroenterology , vol.117 , pp. 368-377
    • Sturm, A.1    Sudermann, T.2    Schulte, K.M.3
  • 53
    • 12344336371 scopus 로고    scopus 로고
    • Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo
    • Graziani G, D'Argenio Z, Tuccillo C, et al. Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo. Gut 2005; 54:193-200.
    • (2005) Gut , vol.54 , pp. 193-200
    • Graziani, G.1    D'Argenio, Z.2    Tuccillo, C.3
  • 54
    • 23644447009 scopus 로고    scopus 로고
    • Mesalamine promotes intestinal epithelial wound healing in vitro through a TGF-beta-independent mechanism
    • Baumgart DC, Vierziger K, Sturm A, et al. Mesalamine promotes intestinal epithelial wound healing in vitro through a TGF-beta-independent mechanism. Scand J Gastroenterol 2005; 40:958-964.
    • (2005) Scand J Gastroenterol , vol.40 , pp. 958-964
    • Baumgart, D.C.1    Vierziger, K.2    Sturm, A.3
  • 55
    • 0031414125 scopus 로고    scopus 로고
    • Histone H3 messenger RNA in situ hybridization for identifying proliferating cells in formalin-fixed rat gastric mucosa
    • Maeyama H, Furuwatari C, Ota H, et al. Histone H3 messenger RNA in situ hybridization for identifying proliferating cells in formalin-fixed rat gastric mucosa. Histochem J 1997; 29:867-873.
    • (1997) Histochem J , vol.29 , pp. 867-873
    • Maeyama, H.1    Furuwatari, C.2    Ota, H.3
  • 56
    • 1942488919 scopus 로고    scopus 로고
    • The assessment of cell proliferation during 9,10-dimethyl-1,2- benzanthracene-induced hamster tongue carcinogenesis by means of histone H3 mRNA in situ hybridisation
    • Sakamoto R, Nitta T, Kamikawa Y, et al. The assessment of cell proliferation during 9,10-dimethyl-1,2-benzanthracene-induced hamster tongue carcinogenesis by means of histone H3 mRNA in situ hybridisation. Med Electron Microsc 2004; 37:52-61.
    • (2004) Med Electron Microsc , vol.37 , pp. 52-61
    • Sakamoto, R.1    Nitta, T.2    Kamikawa, Y.3
  • 57
    • 0034102695 scopus 로고    scopus 로고
    • Apoptosis in the intestinal epithelium: Its relevance in normal and pathophysiological conditions
    • Ramachandran A, Madesh M, Balasubramanian KA. Apoptosis in the intestinal epithelium: its relevance in normal and pathophysiological conditions. J Gastroenterol Hepatol 2000; 15:109-120.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 109-120
    • Ramachandran, A.1    Madesh, M.2    Balasubramanian, K.A.3
  • 58
    • 0038407572 scopus 로고    scopus 로고
    • Apoptotic detection methods: From morphology to gene
    • Otsuki Y, Li Z, Shibata MA. Apoptotic detection methods: from morphology to gene. Prog Histochem Cytochem 2003; 38:275-339.
    • (2003) Prog Histochem Cytochem , vol.38 , pp. 275-339
    • Otsuki, Y.1    Li, Z.2    Shibata, M.A.3
  • 59
    • 0345040854 scopus 로고    scopus 로고
    • Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
    • Leers MP, Kolgen W, Bjorklund V, et al. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol 1999; 187:567-572.
    • (1999) J Pathol , vol.187 , pp. 567-572
    • Leers, M.P.1    Kolgen, W.2    Bjorklund, V.3
  • 60
    • 4143132484 scopus 로고    scopus 로고
    • Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner
    • Ypsilantis P, Tentes I, Assimakopoulos SF, et al. Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner. J Surg Res 2004; 121:84-91.
    • (2004) J Surg Res , vol.121 , pp. 84-91
    • Ypsilantis, P.1    Tentes, I.2    Assimakopoulos, S.F.3
  • 61
    • 17644422766 scopus 로고    scopus 로고
    • Apoptosis in the intestinal mucosa of patients with inflammatory bowel disease: Evidence of altered expression of FasL and perform cytotoxic pathways
    • Souza HS, Tortori CJ, Catelo-Branco MT, et al. Apoptosis in the intestinal mucosa of patients with inflammatory bowel disease: evidence of altered expression of FasL and perform cytotoxic pathways. Int J Colorectal Dis 2005; 20:277-286.
    • (2005) Int J Colorectal Dis , vol.20 , pp. 277-286
    • Souza, H.S.1    Tortori, C.J.2    Catelo-Branco, M.T.3
  • 62
    • 0037942894 scopus 로고    scopus 로고
    • Flow cytometric methods for detection and quantification of apoptosis
    • Steensma DP, Timm M, Witzig TE. Flow cytometric methods for detection and quantification of apoptosis. Methods Mol Med 2003; 85:323-332.
    • (2003) Methods Mol Med , vol.85 , pp. 323-332
    • Steensma, D.P.1    Timm, M.2    Witzig, T.E.3
  • 63
    • 0031888406 scopus 로고    scopus 로고
    • Comparison of in situ methods to assess DNA cleavage in apoptotic cells in patients with breast cancer
    • Mainwaring PN, Ellis PA, Detre S, et al. Comparison of in situ methods to assess DNA cleavage in apoptotic cells in patients with breast cancer. J Clin Pathol 1998; 51:34-37.
    • (1998) J Clin Pathol , vol.51 , pp. 34-37
    • Mainwaring, P.N.1    Ellis, P.A.2    Detre, S.3
  • 64
    • 23844442248 scopus 로고    scopus 로고
    • Epithelial cell turnover in relation to ongoing damage of the gastric mucosa in patients with early gastric cancer: Increase of cell proliferation in paramalignant lesions
    • Shiotani A, Iishi H, Ishiguro S. Epithelial cell turnover in relation to ongoing damage of the gastric mucosa in patients with early gastric cancer: increase of cell proliferation in paramalignant lesions. J Gastroenterol 2005; 40:337-444.
    • (2005) J Gastroenterol , vol.40 , pp. 337-444
    • Shiotani, A.1    Iishi, H.2    Ishiguro, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.