Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats

World Journal of Gastroenterology

Volumn 11, Issue 32, 2005, Pages 4986-4991

  Hei, Zi Qing ^a   Huang, He Qing ^a   Zhang, Jing Jun ^a   Chen, Bing Xue ^a   Li, Xiao Yun ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Astragalus membranaceus; Hemorrhage shock; Intestinal reperfusion injury

Indexed keywords

ASTRAGALUS MEMBRANACEUS EXTRACT; ENDOTHELIN 1; GLUTATHIONE PEROXIDASE; LACTIC ACID; MALONALDEHYDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; HEMORRHAGIC SHOCK; INTESTINE INJURY; INTESTINE MUCOSA; LACTATE BLOOD LEVEL; LOW DRUG DOSE; NONHUMAN; PROTEIN BLOOD LEVEL; RANDOMIZATION; RAT; REPERFUSION INJURY; SCORING SYSTEM; STATISTICAL SIGNIFICANCE;

EID: 24144447669     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i32.4986     Document Type: Article

References (27)

1. Knight DJ, Girling KJ. Gut flora in health and disease. Lancet 2003; 361: 512-519
2. Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease. J Gastroenterol Hepatol 2003; 18: 479-497
3. Meng ZH, Dyer K, Billiar TR, Tweardy DJ. Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock. Am J Physiol Cell Physiol 2001; 280: C343-351
4. Guo W, MagnottiL J, Ding J, Huang Q, Xu D, Deitch EA. Influence of gut microflora on mesenteric lymph cytokine production in rats with hemorrhagic shock. J Trauma 2002; 52: 1178-1185
5. Pape HC, Grotz M, Remmers D, Dwenger A, Vaske R, Wisner D, Tscherne H. Multiple organ failure (MOF) after severe trauma-a sheep model. Intensive Care Med 1998; 24: 590-598
6. Mitsuoka H, Kistler EB, Schmid-Schonbein GW. Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock. Shock 2002; 17: 205-209
7. Bedirli A, Sozuer EM, Muhtaroglu S, Alper M. The role of oxygen free radicals and nitric oxide in organ injury following hemorrhagic shock and reinfusion. Int J Surg Investig 2000; 2: 275-284
8. Mota-Filipe H, Mcdonald MC, Cuzzocrea S, Thiemermann C. A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. Shock 1999; 12: 255-261
9. Hierholzer C, Kalff JC, Billiar TR, Bauer AJ, Tweardy DJ, Harbrecht BG. Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol 2004; 286: G225-233
10. Massberg S, Boros M, Leiderer R, Baranyi L, Okada H, Messmer K. Endothelin (ET)-1 induced mucosal damage in the rat small intestine: role of ET(A) receptors. Shock 1998; 9: 177-183
11. Denizbasi A, Yegen C, Ozturk M, Yegen B. Role of nitric oxide in gastric injury induced by hemorrhagic shock in rats. Pharmacology 2000; 61: 106-112
12. Izumi M, Mcdonald MC, Sharpe MA, Chatterjee PK, Thiemermann C. Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock. Shock 2002; 18: 230-235
13. Wattanasirichaigoon S, Menconi MJ, Fink MP. Lisofylline ameliorates intestinal and hepatic injury induced by hemorrhage and resuscitation in rats. Crit Care Med 2000; 28: 1540-1549
14. Matheson PJ, Wilson MA, Garrison RN. Regulation of intestinal blood flow. J Surg Res 2000; 93: 182-196
15. Morrini S, Yacoub W, Rastellini C, Gaudio E, Watkins SC, Cicalese L. Intestinal microvascular patterns during hemorrhagic shock. Dig Dis Sci 2000; 45: 710-722
16. Nakijma Y, Baudry N, Duranteau J, Vicaut E. Microcirculation in intestinal villi: a comparison between hemorrhagic and endotoxin shock. Am J Respir Crit Care Med 2001; 164(8 Pt 1): 1526-1530
17. Fruchterman TN, Spain DA, Wilson MA, Harris PD, Garrison RN. Selective microvascular endothelial cell dysfunction in the small intestine following resuscitated hemorrhagic shock. Shock 1998; 10: 417-422
18. Mailman D. Modulation of hemorrhagic shock by intestinal mucosal NG-nitro-L-arginine and L-arginine in the anesthetized rat. Shock 1999; 12: 155-160
19. Bauer C, Kuntz W, Ohnsmann F, Gasser H, Weber C, Redl H, Marzi I. The attenuation of hepatic microcirculatory alterations by exogenous substitution of nitric oxide by s-nitroso-human albumin after hemorrhagic shock in the rat. Shock 2004; 21: 165-169
20. Kawata K, Takeyoshi I, Iwanam K, Sunose Y, Aiba M, Ohwada S, Matsumoto K, Morishita Y. A spontaneous nitric oxide dornor ameliorate small bowel ischemia-reperfusion injury in dogs. Dig Dis Sci 2001; 46: 1748-1756
21. Oktar BK, Gulpinar MA, Bozkurt A, Ghandour S, Cetinel S, Moini H, Yegen BC, Bilsel S, Granger DN, Kurtel H. Endothelin receptor blockers reduce I/R-induced intestinal mucosal injury: role of blood flow. Am J Physiol Gastrointest Liver Physiol 2002; 282: G647-G655
22. Anadol AZ, Bayram O, Dursun A, Ercan S. Role of endogenous endothelin peptides in intestinal ischemia-reperfusion injury in rats. Prostaglandins Leukot Essent Fatty Acids 1998; 59: 279-283
23. Akcakaya A, Alimoglu O, Sahin M, Abbasoglu SD. Ischemia-reperfusion injury following superior mesenteric artery occlusion and strangulation obstruction. J Surg Res 2002; 108: 39-43
24. Riaz AA, Wan MX, Schafer T, Dawson P, Menger MD, Jeppsson B, Thorlacius H. Allopurinol and superoxide dismutase protect against leucocyte-endothelium interactions in a novel model of colonic ischaemia-reperfusion. Br J Surg 2002; 89: 1572-1580
25. Cuzzocrea S, Mazzon E, Dugo L, Caputi AP, Aston K, Riley DP, Salvemini D. Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion. Br J Pharmacol 2001; 132: 19-29
26. Muzakova V, Kandar R, Vojtisek P, Skalicky J, Cervinkova Z. Selective antioxidant enzymes during ischemia/reperfusion in myocardial infarction. Physiol Res 2000; 49: 315-322
27. Akcil E, Tug T, Doseyen Z. Antioxidant enzyme activities and trace element concentrations in ischemia-reperfusion. Biol Trace Elem Res 2000; 76: 13-17