-
1
-
-
2942691389
-
Stem cell origin of cancer and differentiation therapy
-
Sell S. (2004). Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 51:1-28.
-
(2004)
Crit Rev Oncol Hematol
, vol.51
, pp. 1-28
-
-
Sell, S.1
-
2
-
-
0029018984
-
The neuroepithelial stem cell concept: Implications for neurooncology
-
Brustle O and RD McKay. (1995). The neuroepithelial stem cell concept: implications for neurooncology. J Neurooncol 24:57-59.
-
(1995)
J Neurooncol
, vol.24
, pp. 57-59
-
-
Brustle, O.1
McKay, R.D.2
-
3
-
-
0033960657
-
A mouse model for glioma: Biology, pathology, and therapeutic opportunities
-
Holland EC. (2000). A mouse model for glioma: biology, pathology, and therapeutic opportunities. Toxicol Pathol 28:171-177.
-
(2000)
Toxicol Pathol
, vol.28
, pp. 171-177
-
-
Holland, E.C.1
-
4
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
Holland EC, J Celestino, C Dai, L Schaefer, RE Sawaya and GN Fuller. (2000). Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nature Genet 25:55-57.
-
(2000)
Nature Genet
, vol.25
, pp. 55-57
-
-
Holland, E.C.1
Celestino, J.2
Dai, C.3
Schaefer, L.4
Sawaya, R.E.5
Fuller, G.N.6
-
5
-
-
0035187893
-
Stem cell potential: Can anything make anything?
-
Morrison SJ. (2001). Stem cell potential: can anything make anything? Curr Biol 11:R7-R9.
-
(2001)
Curr Biol
, vol.11
-
-
Morrison, S.J.1
-
6
-
-
0842281433
-
Therapeutic implications of cancer stem cells
-
Al-Hajj M, MW Becker, M Wicha, I Weissman and MF Clarke. (2004). Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14:43-47.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 43-47
-
-
Al-Hajj, M.1
Becker, M.W.2
Wicha, M.3
Weissman, I.4
Clarke, M.F.5
-
7
-
-
3042525924
-
Breast cancer, stem/progenitor cells and the estrogen receptor
-
Dontu G, D El-Ashry and MS Wicha. (2004). Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol Metab 15:193-197.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 193-197
-
-
Dontu, G.1
El-Ashry, D.2
Wicha, M.S.3
-
8
-
-
0020625285
-
Cellular heterogeneity in tumours
-
Woodruff MF. (1983). Cellular heterogeneity in tumours. Br J Cancer 47:589-594.
-
(1983)
Br J Cancer
, vol.47
, pp. 589-594
-
-
Woodruff, M.F.1
-
9
-
-
0028294877
-
Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers
-
Sell S and GB Pierce. (1994). Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Lab Invest 70:6-22.
-
(1994)
Lab Invest
, vol.70
, pp. 6-22
-
-
Sell, S.1
Pierce, G.B.2
-
10
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, SJ Morrison, MF Clarke and IL Weissman. (2001). Stem cells, cancer, and cancer stem cells. Nature 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
11
-
-
0036336893
-
Stem-cell origin of metastasis and heterogeneity in solid tumours
-
Tu SM, SH Lin and CJ Logothetis. (2002). Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol 3:508-513.
-
(2002)
Lancet Oncol
, vol.3
, pp. 508-513
-
-
Tu, S.M.1
Lin, S.H.2
Logothetis, C.J.3
-
12
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, MS Wicha, A Benito-Hernandez, SJ Morrison and MF Clarke. (2003). Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
13
-
-
0035207448
-
The biology of signal tansduction inhibition: Basic science to novel therapies
-
Griffin J. (2001). The biology of signal tansduction inhibition: basic science to novel therapies. Semin Oncol 28:3-8.
-
(2001)
Semin Oncol
, vol.28
, pp. 3-8
-
-
Griffin, J.1
-
14
-
-
0036467568
-
Rational therapeutic intervention in cancer: Kinases as drug targets
-
Sawyers CL. (2002). Rational therapeutic intervention in cancer: kinases as drug targets. Curr Opin Genet Dev 12:111-115.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 111-115
-
-
Sawyers, C.L.1
-
15
-
-
0034665138
-
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylamino-pyrimidine class
-
Kilic T, JA Alberta, PR Zdunek, M Acar, P Iannarelli and T O'Reilly. (2000). Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylamino-pyrimidine class. Cancer Res 60:5143-5150.
-
(2000)
Cancer Res
, vol.60
, pp. 5143-5150
-
-
Kilic, T.1
Alberta, J.A.2
Zdunek, P.R.3
Acar, M.4
Iannarelli, P.5
O'Reilly, T.6
-
16
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, CL Sawyers, H Kantarjian, DJ Resta, SF Reese and JM Ford. (2001). Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 344:1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
-
17
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
Neshat MS, IK Mellinghoff, C Tran, B Stiles, G Thomas and R Petersen. (2001). Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc Natl Acad Sci USA 98:10314-10319.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
Stiles, B.4
Thomas, G.5
Petersen, R.6
-
18
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, JD Schuetz, KD Bunting, AM Colapietro, J Sampath and JJ Morris. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nature Med 7:1028-1034.
-
(2001)
Nature Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
-
19
-
-
0037125973
-
Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
-
Zhou S, JJ Morris, Y Barnes, L Lan, JD Schuetz and BP Sorrentino. (2002). Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci USA 99:12339-12344.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12339-12344
-
-
Zhou, S.1
Morris, J.J.2
Barnes, Y.3
Lan, L.4
Schuetz, J.D.5
Sorrentino, B.P.6
-
20
-
-
0036364467
-
Multidrug resistance in cancer, role of ATP-dependent transporters
-
Gottesman MM, T Fojo and SE Bates. (2002). Multidrug resistance in cancer, role of ATP-dependent transporters. Nature Rev Cancer 2:48-58.
-
(2002)
Nature Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
21
-
-
0141577218
-
Further evidence favoring the concept of the stem cell in ascites tumors of rats
-
Makino S. (1956). Further evidence favoring the concept of the stem cell in ascites tumors of rats. Ann NY Acad Sci 63:818-830.
-
(1956)
Ann NY Acad Sci
, vol.63
, pp. 818-830
-
-
Makino, S.1
-
22
-
-
84883845299
-
Multipotentiality of single embryonal carcinoma cells
-
Kleinsmith LJ and GB Pierce. (1964). Multipotentiality of single embryonal carcinoma cells. Cancer Res 24:1544-1551.
-
(1964)
Cancer Res
, vol.24
, pp. 1544-1551
-
-
Kleinsmith, L.J.1
Pierce, G.B.2
-
23
-
-
0026546699
-
Leukemia: Stem cells, preleukemia and cure
-
Gale RP and A Butturini. (1992). Leukemia: stem cells, preleukemia and cure. Leukemia 6:80-85.
-
(1992)
Leukemia
, vol.6
, pp. 80-85
-
-
Gale, R.P.1
Butturini, A.2
-
24
-
-
0035883060
-
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
-
Wulf GG, RY Wang, I Kuehnle, D Weidner, F Marini and MK Brenner. (2001). A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 98:1166-1173.
-
(2001)
Blood
, vol.98
, pp. 1166-1173
-
-
Wulf, G.G.1
Wang, R.Y.2
Kuehnle, I.3
Weidner, D.4
Marini, F.5
Brenner, M.K.6
-
25
-
-
1642474273
-
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
-
Kondo T, T Setoguchi, and T Taga. (2004). Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci. USA. 101:781-786.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 781-786
-
-
Kondo, T.1
Setoguchi, T.2
Taga, T.3
-
26
-
-
0037656514
-
Identification of molecular subtypes of glioblastoma by gene expression profiling
-
Mischel PS, R Shai, T Shi, S Horvath, KV Lu and G Choe. (2003). Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene 22:2361-2373.
-
(2003)
Oncogene
, vol.22
, pp. 2361-2373
-
-
Mischel, P.S.1
Shai, R.2
Shi, T.3
Horvath, S.4
Lu, K.V.5
Choe, G.6
-
27
-
-
0038105339
-
Hypoxia-induced dedifferentiation in neuroblastoma cells
-
Jogi A, I Ora, H Nilsson, L Poellinger, H Axelson and S Pahlman. (2003). Hypoxia-induced dedifferentiation in neuroblastoma cells. Cancer Lett 197:145-150.
-
(2003)
Cancer Lett
, vol.197
, pp. 145-150
-
-
Jogi, A.1
Ora, I.2
Nilsson, H.3
Poellinger, L.4
Axelson, H.5
Pahlman, S.6
-
28
-
-
0034491061
-
Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo
-
Holland EC, Y Li, J Celestino, C Dai, L Schaefer and RA Sawaya. (2000). Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo. Am J Pathol 157:1031-1037.
-
(2000)
Am J Pathol
, vol.157
, pp. 1031-1037
-
-
Holland, E.C.1
Li, Y.2
Celestino, J.3
Dai, C.4
Schaefer, L.5
Sawaya, R.A.6
-
29
-
-
0035425048
-
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
-
Dai C, JC Celestino, Y Okada, DN Louis, GN Fuller and EC Holland. (2001). PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15:1913-1925.
-
(2001)
Genes Dev
, vol.15
, pp. 1913-1925
-
-
Dai, C.1
Celestino, J.C.2
Okada, Y.3
Louis, D.N.4
Fuller, G.N.5
Holland, E.C.6
-
30
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, EA Maher, KL Ligon, NE Sharpless, SS Chan and MJ You. (2002). Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 1:269-277.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
Sharpless, N.E.4
Chan, S.S.5
You, M.J.6
-
31
-
-
1842861743
-
Human neuroblastoma cells exposed to hypoxia: Induction of genes associated with growth, survival, and aggressive behavior
-
Jogi A, J Vallon-Christersson, L Holmquist, H Axelson, A Borg and S Pahlman. (2004). Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior. Exp Cell Res 295:469-487.
-
(2004)
Exp Cell Res
, vol.295
, pp. 469-487
-
-
Jogi, A.1
Vallon-Christersson, J.2
Holmquist, L.3
Axelson, H.4
Borg, A.5
Pahlman, S.6
-
32
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B and KW Kinzler KW. (2004). Cancer genes and the pathways they control. Nat Med 10:789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler Kw, K.W.2
-
33
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub TR, DK Slonim, P Tamayo, C Huard, M Gaasenbeek and JP Mesirov. (1999). Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science 286:531-537.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
-
34
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh AA, MB Eisen, RE Davis, C Ma, IS Lossos, AJ Rosenwald and C Boldrick. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503-511.
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
Ma, C.4
Lossos, I.S.5
Rosenwald, A.J.6
Boldrick, C.7
-
35
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, T Sorlie, MB Eisen, M van de Rijn, SS Jeffrey and CA Rees. (2000). Molecular portraits of human breast tumours. Nature 406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
-
36
-
-
0034794796
-
Expression profiling of medulloblastoma: PDGFRA and RAS/MAPK pathway as therapeutic targets for metastatic disease
-
MacDonald TJ, KM Brown, B LaFleur, K Peterson, C Lawlor and Y Chen. (2001). Expression profiling of medulloblastoma: PDGFRA and RAS/MAPK pathway as therapeutic targets for metastatic disease. Nat Genet 29: 143-152.
-
(2001)
Nat Genet
, vol.29
, pp. 143-152
-
-
MacDonald, T.J.1
Brown, K.M.2
Lafleur, B.3
Peterson, K.4
Lawlor, C.5
Chen, Y.6
|