-
2
-
-
0031013848
-
Prevalence of Parkinsonism and Parkinson's disease in Europe: the Europarkinson collaborative
-
de Rijk M.C., Tzourio C., Breteler M.M., F Dartigues J., Amaducci L., Lopez-Pousa S., Manubens-Bertran J.M., Alperovitch A., and Rocca W.A. Prevalence of Parkinsonism and Parkinson's disease in Europe: the Europarkinson collaborative. J. Neurol. Neurosurg. Psychiatry 62 (1997) 10-15
-
(1997)
J. Neurol. Neurosurg. Psychiatry
, vol.62
, pp. 10-15
-
-
de Rijk, M.C.1
Tzourio, C.2
Breteler, M.M.3
F Dartigues, J.4
Amaducci, L.5
Lopez-Pousa, S.6
Manubens-Bertran, J.M.7
Alperovitch, A.8
Rocca, W.A.9
-
3
-
-
1842455356
-
Parkin genetics: one model for Parkinson's disease
-
Review Issue 1
-
Mata I.F., Lockhart P.J., and Farrer M.J. Parkin genetics: one model for Parkinson's disease. Hum. Mol. Genet. 13 (2004) R127-R133 Review Issue 1
-
(2004)
Hum. Mol. Genet.
, vol.13
-
-
Mata, I.F.1
Lockhart, P.J.2
Farrer, M.J.3
-
5
-
-
0038727936
-
Description of Parkinson's disease as a clinical syndrome
-
Fahn S. Description of Parkinson's disease as a clinical syndrome. Ann. N.Y Acad. Sci. (2003) 1-14
-
(2003)
Ann. N.Y Acad. Sci.
, pp. 1-14
-
-
Fahn, S.1
-
6
-
-
0029981526
-
Neuropathology of Parkinson's disease
-
Forno L.S. Neuropathology of Parkinson's disease. J. Neuropathol. Exp. Neurol. 55 (1996) 259-272
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 259-272
-
-
Forno, L.S.1
-
7
-
-
17844365594
-
Genetics of Parkinson's disease
-
Morris H.R. Genetics of Parkinson's disease. Ann. Med. 37 (2005) 86-96
-
(2005)
Ann. Med.
, vol.37
, pp. 86-96
-
-
Morris, H.R.1
-
8
-
-
0028198309
-
Familial juvenile Parkinsonism: clinical and pathologic study in a family
-
Takahashi H., Ohama E., Suzuki S., Horikawa Y., Ishikawa A., Morita T., Tsuji S., and Ikuta F. Familial juvenile Parkinsonism: clinical and pathologic study in a family. Neurology 44 (1994) 437-441
-
(1994)
Neurology
, vol.44
, pp. 437-441
-
-
Takahashi, H.1
Ohama, E.2
Suzuki, S.3
Horikawa, Y.4
Ishikawa, A.5
Morita, T.6
Tsuji, S.7
Ikuta, F.8
-
9
-
-
0031721141
-
Pathologic and biochemical studies of juvenile Parkinsonism linked to chromosome 6q
-
Mori H., Kondo T., Yokochi M., Matsumine H., Nakagawa-Hattori Y., Miyake T., Suda K., and Mizuno Y. Pathologic and biochemical studies of juvenile Parkinsonism linked to chromosome 6q. Neurology 51 (1998) 890-892
-
(1998)
Neurology
, vol.51
, pp. 890-892
-
-
Mori, H.1
Kondo, T.2
Yokochi, M.3
Matsumine, H.4
Nakagawa-Hattori, Y.5
Miyake, T.6
Suda, K.7
Mizuno, Y.8
-
10
-
-
0342368772
-
French Parkinson's disease genetics study group; European consortium on genetic susceptibility in Parkinson's disease. Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lücking C.B., Durr A., Bonifati V., Vaughan J., De Michele G., Gasser T., Harhangi B.S., Meco G., Denefle P., Wood N.W., Agid Y., and Brice A. French Parkinson's disease genetics study group; European consortium on genetic susceptibility in Parkinson's disease. Association between early-onset Parkinson's disease and mutations in the parkin gene. N. Engl. J. Med. 342 (2000) 1560-1567
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1560-1567
-
-
Lücking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
11
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile Parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., and Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile Parkinsonism. Nature 392 (1998) 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
12
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H., Hattori N., Kubo S., Mizuno Y., Asakawa S., Minoshima S., Shimizu N., Iwai K., Chiba T., Tanaka K., and Suzuki T. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25 (2000) 302-305
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
13
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y., Gao J., Chung K.K., Huang H., Dawson V.L., and Dawson T.M. Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. USA 97 (2000) 13354-13359
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
-
14
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin
-
Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., and Takahashi Y. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin. Cell 105 (2001) 891-902
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, Y.6
-
16
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction
-
Glickman M.H., and Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol. Rev. 82 (2002) 373-428
-
(2002)
Physiol. Rev.
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
18
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
-
Chung K.K., Zhang Y., Lim K.L., Tanaka Y., Huang H., Gao J., Ross C.A., Dawson V.L., and Dawson T.M. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med. 7 (2001) 1144-1150
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
19
-
-
0035854437
-
Ubiquitination of a new form of synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H., Schlossmacher M., Hattori N., Frosch M., Trockenbacher A., Schneider R., Mizuno Y., Kosik K., and Selkoe D. Ubiquitination of a new form of synuclein by parkin from human brain: Implications for Parkinson's disease. Science 293 (2001) 263-269
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.2
Hattori, N.3
Frosch, M.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.8
Selkoe, D.9
-
20
-
-
0142059791
-
Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1
-
Dong Z., Ferger B., Paterna J.C., Vogel D., Furler S., Osinde M., Feldon J., and Bueler H. Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1. Proc. Natl. Acad. Sci. USA 100 (2003) 12438-12443
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12438-12443
-
-
Dong, Z.1
Ferger, B.2
Paterna, J.C.3
Vogel, D.4
Furler, S.5
Osinde, M.6
Feldon, J.7
Bueler, H.8
-
21
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang Y., Nishimura I., Imai Y., Takahashi R., and Lu B. Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron. 37 (2003) 911-924
-
(2003)
Neuron.
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
22
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive Parkinsonism in Europe
-
Abbas N., Lücking C., Ricard S., Dürr A., Bonifati V., De Michele G., Bouley S., Vaughan J., Gasser T., Marconi R., Broussolle E., Brefel-Courbon C., Harhangi B., Oostra B., Fabrizio E., Böhme G., Pradier L., Wood N., Filla A., Meco G., Denefle P., Agid Y., and Brice A. A wide variety of mutations in the parkin gene are responsible for autosomal recessive Parkinsonism in Europe. Hum. Mol. Genet. 8 (1999) 567-574
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 567-574
-
-
Abbas, N.1
Lücking, C.2
Ricard, S.3
Dürr, A.4
Bonifati, V.5
De Michele, G.6
Bouley, S.7
Vaughan, J.8
Gasser, T.9
Marconi, R.10
Broussolle, E.11
Brefel-Courbon, C.12
Harhangi, B.13
Oostra, B.14
Fabrizio, E.15
Böhme, G.16
Pradier, L.17
Wood, N.18
Filla, A.19
Meco, G.20
Denefle, P.21
Agid, Y.22
Brice, A.23
more..
-
23
-
-
0035092090
-
French Parkinson's disease genetics study group, the European consortium on genetic susceptibility in Parkinson's disease, origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from founder effects
-
Periquet M., Lucking C., Vaughan J., Bonifati V., Durr A., De Michele G., Horstink M., Farrer M., Illarioshkin S.N., Pollak P., Borg M., Brefel-Courbon C., Denefle P., Meco G., Gasser T., M Breteler M., Wood N., Agid Y., and Brice A. French Parkinson's disease genetics study group, the European consortium on genetic susceptibility in Parkinson's disease, origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from founder effects. Am. J. Hum. Genet. 68 (2001) 617-626
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 617-626
-
-
Periquet, M.1
Lucking, C.2
Vaughan, J.3
Bonifati, V.4
Durr, A.5
De Michele, G.6
Horstink, M.7
Farrer, M.8
Illarioshkin, S.N.9
Pollak, P.10
Borg, M.11
Brefel-Courbon, C.12
Denefle, P.13
Meco, G.14
Gasser, T.15
M Breteler, M.16
Wood, N.17
Agid, Y.18
Brice, A.19
-
24
-
-
0030055054
-
A somatic cell hybrid panel for pig regional gene mapping characterized by molecular cytogenetics
-
Yerle M., Echard G., Robic A., Mairal A., Dubut-Fontana C., Riquet J., Pinton P., Milan D., Lahbib-Mansais Y., and Gellin J. A somatic cell hybrid panel for pig regional gene mapping characterized by molecular cytogenetics. Cytogenet. Cell Genet. 73 (1996) 194-202
-
(1996)
Cytogenet. Cell Genet.
, vol.73
, pp. 194-202
-
-
Yerle, M.1
Echard, G.2
Robic, A.3
Mairal, A.4
Dubut-Fontana, C.5
Riquet, J.6
Pinton, P.7
Milan, D.8
Lahbib-Mansais, Y.9
Gellin, J.10
-
25
-
-
0035545095
-
Assignment of the mouse Park2 (PARKIN), the homologue to a new human Parkinson candidate gene, to the telomeric region of mouse 17A3.2-3.3, by in situ hybridization
-
Tomac A.C., and Hoffer B.J. Assignment of the mouse Park2 (PARKIN), the homologue to a new human Parkinson candidate gene, to the telomeric region of mouse 17A3.2-3.3, by in situ hybridization. Cytogenet. Cell Genet. 95 (2001) 120-121
-
(2001)
Cytogenet. Cell Genet.
, vol.95
, pp. 120-121
-
-
Tomac, A.C.1
Hoffer, B.J.2
-
26
-
-
0034044667
-
Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene
-
Kitada T., Asakawa S., Minoshima S., Mizuno Y., and Shimizu N. Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene. Mamm. Genome 11 (2000) 417-421
-
(2000)
Mamm. Genome
, vol.11
, pp. 417-421
-
-
Kitada, T.1
Asakawa, S.2
Minoshima, S.3
Mizuno, Y.4
Shimizu, N.5
-
27
-
-
0032564235
-
Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile Parkinsonism. The European consortium on genetic susceptibility in Parkinson's disease and the French Parkinson's disease genetics study group
-
Lücking C.B., Abbas N., Durr A., Bonifati V., Bonnet A.M., de Broucker T., De Michele G., Wood N.W., Agid Y., and Brice A. Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile Parkinsonism. The European consortium on genetic susceptibility in Parkinson's disease and the French Parkinson's disease genetics study group. Lancet 352 (1998) 1355-1360
-
(1998)
Lancet
, vol.352
, pp. 1355-1360
-
-
Lücking, C.B.1
Abbas, N.2
Durr, A.3
Bonifati, V.4
Bonnet, A.M.5
de Broucker, T.6
De Michele, G.7
Wood, N.W.8
Agid, Y.9
Brice, A.10
-
28
-
-
33646138464
-
Detection of compound heterozygous deletions in the parkin gene of fibroblasts in patients with autosomal recessive hereditary parkinsonism
-
Nakaso K., Adachi Y., Yasui K., Sakuma K., and Nakashima K. Detection of compound heterozygous deletions in the parkin gene of fibroblasts in patients with autosomal recessive hereditary parkinsonism. Neurosci. Lett. 400 (2006) 44-47
-
(2006)
Neurosci. Lett.
, vol.400
, pp. 44-47
-
-
Nakaso, K.1
Adachi, Y.2
Yasui, K.3
Sakuma, K.4
Nakashima, K.5
-
29
-
-
0035421416
-
The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset Parkinsonism
-
Hedrich K., Kann M., Lanthaler A.J., Dalski A., Eskelson C., Landt O., Schwinger E., Vieregge P., Lang A.E., Breakefield X.O., Ozelius L.J., Pramstaller P.P., and Klein C. The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset Parkinsonism. Hum. Mol. Genet. 10 (2001) 1649-1656
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1649-1656
-
-
Hedrich, K.1
Kann, M.2
Lanthaler, A.J.3
Dalski, A.4
Eskelson, C.5
Landt, O.6
Schwinger, E.7
Vieregge, P.8
Lang, A.E.9
Breakefield, X.O.10
Ozelius, L.J.11
Pramstaller, P.P.12
Klein, C.13
-
30
-
-
0038754178
-
Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
-
Oliveira S.A., Scott W.K., Martin E.R., Nance M.A., Watts R.L., Hubble J.P., Collar W.C., Pahwa R., Stern M.B., Hiner B.C., Ondo W.G., Allen Jr. F.H., Scott B.L., Goetz C.G., Small G.W., Mastaglia F., Satanic J.M., Zhang F., Booze M.W., Winn M.P., Middleton L.T., Haines J.L., Pericak-Vance M.A., and Vance J.M. Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. Ann. Neurol. 53 (2003) 624-629
-
(2003)
Ann. Neurol.
, vol.53
, pp. 624-629
-
-
Oliveira, S.A.1
Scott, W.K.2
Martin, E.R.3
Nance, M.A.4
Watts, R.L.5
Hubble, J.P.6
Collar, W.C.7
Pahwa, R.8
Stern, M.B.9
Hiner, B.C.10
Ondo, W.G.11
Allen Jr., F.H.12
Scott, B.L.13
Goetz, C.G.14
Small, G.W.15
Mastaglia, F.16
Satanic, J.M.17
Zhang, F.18
Booze, M.W.19
Winn, M.P.20
Middleton, L.T.21
Haines, J.L.22
Pericak-Vance, M.A.23
Vance, J.M.24
more..
-
32
-
-
0035793478
-
A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia
-
Pineda-Trujillo N., Carvajal-Carmona L.G., Buritica O., Moreno S., Uribe C., Pineda D., Toro M., Garcia F., Arias W., Bedoya G., Lopera F., and Ruiz-Linares A. A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia. Neurosci. Lett. 298 (2001) 87-90
-
(2001)
Neurosci. Lett.
, vol.298
, pp. 87-90
-
-
Pineda-Trujillo, N.1
Carvajal-Carmona, L.G.2
Buritica, O.3
Moreno, S.4
Uribe, C.5
Pineda, D.6
Toro, M.7
Garcia, F.8
Arias, W.9
Bedoya, G.10
Lopera, F.11
Ruiz-Linares, A.12
-
33
-
-
0032957883
-
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile Parkinsonism patients
-
Shimura H., Hattori N., Kubo S., Yoshikawa M., Kitada T., Matsumine H., Asakawa S., Minoshima S., Yamamura Y., Shimizu N., and Mizuno Y. Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile Parkinsonism patients. Ann. Neurol. 45 (1999) 668-672
-
(1999)
Ann. Neurol.
, vol.45
, pp. 668-672
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Yoshikawa, M.4
Kitada, T.5
Matsumine, H.6
Asakawa, S.7
Minoshima, S.8
Yamamura, Y.9
Shimizu, N.10
Mizuno, Y.11
-
34
-
-
0034326934
-
Does failure of parkin-mediated ubiquitination cause juvenile Parkinsonism?
-
Kahle P.J., Leimer U., and Haass C. Does failure of parkin-mediated ubiquitination cause juvenile Parkinsonism?. Trends Biochem. Sci. 25 (2000) 524-527
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 524-527
-
-
Kahle, P.J.1
Leimer, U.2
Haass, C.3
-
35
-
-
26844527655
-
Genetic mouse models of Parkinsonism: strengths and limitations
-
Fleming S.M., Fernagut P.O., and Chesselet M.F. Genetic mouse models of Parkinsonism: strengths and limitations. NeuroRx 2 (2005) 495-503
-
(2005)
NeuroRx
, vol.2
, pp. 495-503
-
-
Fleming, S.M.1
Fernagut, P.O.2
Chesselet, M.F.3
-
36
-
-
33644862373
-
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
-
Whitworth A.J., Wes P.D., and Pallanck L.J. Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. DDT 11 (2006) 119-126
-
(2006)
DDT
, vol.11
, pp. 119-126
-
-
Whitworth, A.J.1
Wes, P.D.2
Pallanck, L.J.3
-
37
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg M.S., Fleming S.M., Palacino J.J., Cepeda C., Lam H.A., Bhatnagar A., Meloni E.G., Wu N., Ackerson L.C., Klapstein G.J., Gajendiran M., Roth B.L., Chesselet M.F., Maidment N.T., Levine M.S., and Shen J. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J. Biol. Chem. 278 (2003) 43628-43635
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
|