Linking ubiquitin, parkin and synphilin-1

Nature Medicine

Volumn 7, Issue 10, 2001, Pages 1108-1109

  Ciechanover, A ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; LIGASE; PARKIN; SYNPHILIN 1; UBIQUITIN; UNCLASSIFIED DRUG;

AUTOSOMAL RECESSIVE DISORDER; CELL CYCLE; CELL GROWTH; DEGENERATIVE DISEASE; GENE INACTIVATION; GENETIC LINKAGE; HUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN SECRETION; SHORT SURVEY;

ANIMALS; CARRIER PROTEINS; HUMANS; LIGASES; NERVE TISSUE PROTEINS; PARKINSON DISEASE; SYNUCLEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0034770604     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1001-1108     Document Type: Short Survey

References (7)

1. Parkin ubiquitinates the α-synuclein-interacting protein synphilin-1: Implications for Lewy body formation in Parkinson disease
2. Themes and variations on ubiquitylation
3. The 26S proteasome: A molecular machine designed for controlled proteolysis
4. Familial Parkinson disease gene product, Parkin, is a ubiquitin-protein ligase
5. Mutations in the Parkin gene cause autosomal recessive juvenile parkinsonism
6. Ubiquitination of a new form of α-synuclein by Parkin from human brain: Implications for Parkinson's disease
7. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice