DNA damage, redox changes, and associated stress-inducible signaling events underlying the apoptosis and cytotoxicity in murine alveolar macrophage cell line MH-S by methanol-extracted Stachybotrys chartarum toxins

Toxicology and Applied Pharmacology

Volumn 214, Issue 3, 2006, Pages 297-308

  Wang, Huiyan ^a   Yadav, Jagjit S ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Alveolar macrophages; Apoptosis; DNA damage; Indoor mold; MAPK; Mycotoxin; p53; Stachybotrys chartarum; Trichothecenes

Indexed keywords

CASPASE 3; CASPASE 7; CYTOKINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; METHANOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOTOXIN; NITRIC OXIDE; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TRICHOTHECENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CELL STRUCTURE; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME RELEASE; GEL ELECTROPHORESIS; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; STACHYBOTRYS CHARTARUM; STRESS;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; GLUTATHIONE; MACROPHAGES, ALVEOLAR; METHANOL; MICE; MICRONUCLEUS TESTS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MYCOTOXINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; STACHYBOTRYS; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE; STACHYBOTRYS CHARTARUM;

EID: 33745983853     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.01.002     Document Type: Article

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