Study of toxin production by isolates of Stachybotrys chartarum and Memnoniella echinata isolated during a study of pulmonary hemosiderosis in infants

Applied and Environmental Microbiology

Volumn 64, Issue 10, 1998, Pages 3620-3625

  Jarvis, Bruce B ^a   Sorenson, W G ^b   Hintikka, Eeva Liisa ^c   Nikulin, Marjo ^d   Zhou, Yihong ^a   Jiang, Jian ^a   Wang, Shengun ^a   Hinkley, Simon ^a   Etzel, Ruth A ^e   Dearborn, D ^f  

^a Bldg 142   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c NATL VET AND FOOD RES INSTITUTE   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; GRISEOFULVIN; ISOSATRATOXIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATION; CYTOTOXICITY; DATA ANALYSIS; DISEASE SEVERITY; EPIDEMIOLOGICAL DATA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPHOMYCETES; INFANT; LUNG HEMORRHAGE; LUNG HEMOSIDEROSIS; SYMPTOMATOLOGY; TOXICITY; UNITED STATES;

BACTERIA (MICROORGANISMS); FUNGI; HYPHOMYCETES; MEMNONIELLA; STACHYBOTRYS CHARTARUM; STACHYBOTRYS ECHINATA;

EID: 0031657468     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.64.10.3620-3625.1998     Document Type: Article

References (40)

1. Anonymous. 1995. Guidelines on assessment and remediation of Stachybotrys atra in indoor environments, p. 201-207. In E. Johanning and C. S. Yang (ed.), Fungi and bacteria in indoor air environments. Eastern New York Occupational Health Program, Latham, N.Y.
2. Ayer, W. A., and S. Miao. 1993. Secondary metabolites of the aspen fungus Stachybotrys cylindrospora. Can. J. Chem. 71:487-493.
3. Cole, R. J., and R. H. Cox. 1981. Handbook of toxic fungal metabolites. Academic Press, New York, N.Y.
4. Creasia, D. A., J. D. Thurman, R. W. Wannemacher, Jr., and D. L. Bunner. 1990. Acute inhalation toxicity of T-2 mycotoxin in the rat and guinea pig. Fundam. Appl. Toxicol. 53:1370-1375.
5. Croft, W. A., B. B. Jarvis, and C. S. Yatawara. 1986. Airborne outbreak of trichothecene toxicosis. Atmos. Environ. 20:549-552.
6. Demain, A. I. 1995. Why do microorganisms produce antimicrobials?, p. 205-239. In P. A. Hunter, G. K. Darby, and N. J. Russell (ed.), Fifty years of antimicrobials: past perspectives and future trends. Cambridge University Press, New York, N.Y.
7. Dombrink-Kurtzman, M. A., G. A. Bennet, and J. L. Richard. 1994. An optimized MTT bioassay for determination of cytotoxicity of fumonisin in turkey lymphocytes. J. Assoc. Off. Anal. Chem. Int. 72:512-516.
8. Eppley, R. M., and W. J. Bailey. 1973. 12,13-Epoxy-9-trichothecenes as the probable mycotoxins responsible for stachybotryotoxicosis. Science 181:758-760.
9. Eppley, R. M., E. P. Mazzola, M. E. Stack, and P. A. Dreifus. 1980. Structures of satratoxin F and satratoxin G, metabolites of Stachybotrys atra: application of proton and carbon-13 nuclear magnetic resonance spectroscopy. J. Org. Chem. 45:2522-2523.
10. Etzel, R. A., E. Montana, W. G. Sorenson, G. Kullman, J. D. Miller, B. Jarvis, and D. G. Dearborn. 1996. Pulmonary hemosiderosis associated with exposure to Stachybotrys atra. Epidemiology 7:S38.
11. Flannigan, B., and J. D. Miller. 1994. Health implications of fungi in indoor environments - an overview, p. 3-28. In R. Samson, B. Flannigan, M. Flannigan, and S. Graveson (ed.), Health implication of fungi in indoor environments. Elsevier, Amsterdam, The Netherlands.
12. Forgacs, J. 1972. Stachybotrytoxicosis, p. 95-128. In S. Kadis, A. Ciegler, and S. J. Ajl (ed.), Microbial toxins, vol. VIII. Academic Press, Inc., New York, N.Y.
13. Frisvad, J. 1989. The connection between the penicillia and aspergilli and mycotoxins with special emphasis on misidentified isolates. J. Arch. Environ. Contam. Toxicol. 18:452-467.
14. Harrach, B., M. Nummi, M. L. Niku-Paavola, C. J. Mirocha, and M. Palyusik. 1982. Identification of "water-soluble" toxins produced by a Stachybotrys atra strain from Finland. Appl. Environ. Microbiol. 44:494-495.
15. Jarvis, B. B. 1991. Macrocyclic trichothecenes, p. 361-421. In R. P. Sharma and D. K. Salunkhe (ed.), Mycotoxins and phytoalexins in human and animal health. CRC Press, Boca Raton, Fla.
16. Jarvis, B. B. 1992. Macrocyclic trichothecenes from Brazilian Baccharis species: from microanalysis to large scale isolation. Phytochem. Anal. 3:241-249.
17. Jarvis, B. B., J. Salemme, and A. Morais. 1995. Stachybotrys toxins. 1. Nat. Toxins 3:10-16.
18. Jarvis, B. B., V. M. Vrudhula, J. O. Midiwo, and E. P. Mazzola. 1983. New trichothecenes from Myrothecium verrucaria: verrol and 12,13-deoxytrichodermadiene. J. Org. Chem. 48:2576-2580.
19. Jarvis, B. B., Y. Zhou, J. Jiang, S. Wang, W. G. Sorenson, E. Hintikka, M. Nikulin, P. Parikka, R. A. Etzel, and D. G. Dearborn. 1996. Toxigenic molds in water-damaged buildings: dechlorogriseofulvins from Memnoniella echinata. J. Nat. Prod. 59:553-554.
20. Johanning, E. 1995. Health problems related to fungal exposure - the example of toxigenic Stachybotrys charatum (atra), p. 169-182. In E. Johnanning and C. S. Yang (ed.), Fungi and bacteria in indoor air environments. Eastern New York Occupational Health Program, Latham, N.Y.
21. Johanning, E., R. Biagini, D. Hull, P. Morey, B. B. Jarvis, and P. Landsbergis. 1996. Health and immunology study following exposure to toxigenic fungi (Stachybotrys chartarum) in a water-damaged office environment. Int. Arch. Occup. Environ. Health 68:207-218.
22. Johanning, E., P. R. Morey, and B. B. Jarvis. 1993. Clinical-epidemiological investigation of health effects caused by Stachybotrys atra building contamination. Indoor Air '93 1:225-230.
23. Jong, S. C., and E. E. Davis. 1976. Contribution to the knowledge of Stachybotrys and Memnoniella in culture. Mycotaxon 3:409-485.
24. Kaneto, R., K. Dobashi, I. Kojima, K. Sakai, N. Shibamoto, T. Yoshioka, H. Nishida, R. Okamoto, H. Akagawa, and S. Mizuno. 1994. Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp. J. Antibiot. 47:727-730.
25. Lam, Y., K. T. Wichmann, M. S. Meinz, L. Guariglia, R. A. Giacobbie, S. Mochales, L. Kong, S. S. Honeycutt, D. Zink, G. F. Bills, L. Huang, R. W. Burg, R. L. Monaghan, R. Jackson, G. Reid, J. J. Maguire, A. T. McKnight, and C. I. Ragan. 1992. A novel inositol mono-phosphatase inhibitor from Memnoniella echinata: producing organism, fermentation, isolation, physiochemical and in vitro biological properties. J. Antibiot. 45:1397-1403.
26. Miller, J. D. 1992. Fungi as contaminants in indoor air. Atmos. Environ. 26: 2163-2172.
27. Miller, J. D. 1993. Fungi and the building engineer, p. 147-159. In Approaches to assessment of the microbial flora of buildings. ASHRAE publication IAQ 92. Environments for Healthy People. American Society of Heating, Refrigeration and Air-Conditioning Engineers, Atlanta, Ga.
28. Miller, J. D. 1995. Quantification of health effects of combined exposures: a new beginning, p. 159-168. In L. Morawska (ed.), Indoor air quality - an integrated approach. Elsevier, Amsterdam, The Netherlands.
29. Montana, E., R. A. Etzel, T. Allan, T. E. Horgan, and D. G. Dearborn. 1997. Environmental risk factors associated with pediatric idiopathic pulmonary hemorrhage/hemosiderosis in a Cleveland community. Pediatrics 99:117-124.
30. Nikulin, M., A.-L. Pasenen, S. Berg, and E.-L. Hintikka. 1994. Stachybotrys atra growth and toxin production in some building materials and fodder under different relative humidities. Appl. Environ. Microbiol. 60:3421-3424.
31. Nikulin, M., K. E. Reijula, B. B. Jarvis, and E.-L. Hintikka. 1996. Experimental lung mycotoxicosis in mice induced by Stachybotrys atra. Int. J. Exp. Pathol. 77:213-218.
32. Nikulin, M., K. E. Reijula, B. B. Jarvis, P. Veijalainen, and E.-L. Hintikka. 1997. Effects of internasal exposure to spores of Stachybotrys atra in mice. Fundam. Appl. Toxicol. 35:182-188.
33. Nummi, M., and M. L. Niku-Paavola. 1977. Water soluble toxins of Stachybotrys alternons. Ann. Nutr. Aliment. 31:761-770.
34. Ogawa, K., M. Nakamura, M. Hayashi, S. Yaginuma, S. Yamamoto, F. Furihata, K. Shinya, and H. Seto. 1995. Stachybocins, novel endothelin antagonists produced by Stachybotrys sp. M6222.2. Structure determination of stachybocin-A, stachybocin-B and stachybocin-C. J. Antibiot. 48:1396-1400.
35. Roggo, B. E., P. Hug, S. Moss, A. Stämpeli, H.-P. Kriempler, and H. H. Peter. 1996. Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. II. Structure determination. J. Antibiot. 49:374-379.
36. Roggo, B. E., F. Petersen, M. Silla, J. L. Roesel, T. Moerker, and H. H. Peter. 1996. Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. J. Antibiot. 49:13-19.
37. Sakamoto, K., E. Tsujii, M. Miyauchi, T. Nakanishi, M. Yamashita, N. Shigematsu, T. Tada, S. Izumi, and M. Okuhara. 1993. FR901459, a novel immunosuppressant isolated from Stachybotrys chartarum no. 19392. J. Antibiot. 46:1788-1798.
38. Smith, J. E., J. G. Anderson, C. W. Lewis, and Y. M. Murad. 1992. Cytotoxic fungal spores in the indoor air atmosphere of the damp domestic environment. FEMS Microbiol. Lett. 100:337-344.
39. Sorenson, W. G., D. G. Frazer, B. B. Jarvis, J. Simpson, and V. A. Robinson. 1987. Trichothecene mycotoxins in aerosolized conidia of Stachybotrys atra. Appl. Environ. Microbiol. 53:1370-1375.
40. Sorenson, W. G., B. B. Jarvis, Y. Zhou, J. Jiang, S. Wang, E.-L. Hintikka, and M. Nikulin. 1996. Toxine im Zusammenhang mit Stachybotrys and Memnoniella in Häusern mit Wasserschaden, p. 207-214. In M. Gareis and R. Scheuer (ed.), 18. Mykotoxin Workshop. Institut für Mikobiologie und Toxikologie der Bundesanstalt für Fleischforschung, Kulmbach, Germany.