Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 8, 2000, Pages 1585-1588

  Mackay, Katrina ^a   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Ischemia; p38 MAPK; Phosphatase; Vanadate

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME INHIBITION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033867613     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1194     Document Type: Article

References (14)

1. An inhibitor of p38 mitogen-activated protein kinase protects neonatal rat cardiac myoctes from ischemia
2. Role of p38 MAP kinase in myocardial stress
3. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
4. Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease
5. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
6. A dual function for p38 MAP kinase in hematopoietic cells: Involvement in apoptosis and cell activation
7. Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases
8. Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis
9. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
10. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
11. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
12. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
13. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases
14. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation