메뉴 건너뛰기




Volumn 10, Issue 3, 2004, Pages 190-200

Eicosapentaenoic acid induces fas-mediated apoptosis through a p53-dependent pathway in hepatoma cells

Author keywords

Apoptosis; Eicosapentaenoic acid; Fas; Hepatocellular carcinoma; p53

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; FAS ANTIGEN; ICOSAPENTAENOIC ACID; MESSENGER RNA; PROTEIN P53; FAS LIGAND; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN;

EID: 4644310836     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/00130404-200405000-00009     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 0028332826 scopus 로고
    • Treatment of hepatocellular carcinoma: Too many options?
    • Venook AP. Treatment of hepatocellular carcinoma: too many options? J Clin Oncol 1994;12:1323-1334.
    • (1994) J Clin Oncol , vol.12 , pp. 1323-1334
    • Venook, A.P.1
  • 2
    • 0031893533 scopus 로고    scopus 로고
    • The long term efficacy of combined transcatheter arterial embolization and percutaneous ethanol injection in the treatment of patients with large hepatocellular carcinoma and cirrhosis
    • Tanaka K, Nakamura S, Numata K et al. The long term efficacy of combined transcatheter arterial embolization and percutaneous ethanol injection in the treatment of patients with large hepatocellular carcinoma and cirrhosis. Cancer 1998;82:78-85.
    • (1998) Cancer , vol.82 , pp. 78-85
    • Tanaka, K.1    Nakamura, S.2    Numata, K.3
  • 3
    • 0029065587 scopus 로고
    • Therapy of unresectable hepatocellular carcinoma
    • Levin B, Amos C. Therapy of unresectable hepatocellular carcinoma. N Engl J Med 1995;332:1294-1296.
    • (1995) N Engl J Med , vol.332 , pp. 1294-1296
    • Levin, B.1    Amos, C.2
  • 4
    • 0027230578 scopus 로고
    • Postresection prognosis of patients with hepatocellular carcinoma
    • Sugioka A, Tsuzuki T, Kanai T. Postresection prognosis of patients with hepatocellular carcinoma. Surgery 1993;113:612-618.
    • (1993) Surgery , vol.113 , pp. 612-618
    • Sugioka, A.1    Tsuzuki, T.2    Kanai, T.3
  • 5
    • 0029822029 scopus 로고    scopus 로고
    • Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vitro
    • Lai PB, Ross JA, Fearon KC et al. Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vitro. Br J Cancer 1996;74:1375-1383.
    • (1996) Br J Cancer , vol.74 , pp. 1375-1383
    • Lai, P.B.1    Ross, J.A.2    Fearon, K.C.3
  • 6
    • 0032886232 scopus 로고    scopus 로고
    • Induction of apoptosis in HL-60 cells by eicosapentaenoic acid (EPA) is associated with downregulation of bcl-2 expression
    • Chiu LC, Wan JM. Induction of apoptosis in HL-60 cells by eicosapentaenoic acid (EPA) is associated with downregulation of bcl-2 expression. Cancer Lett 1999;145:17-27.
    • (1999) Cancer Lett , vol.145 , pp. 17-27
    • Chiu, L.C.1    Wan, J.M.2
  • 7
    • 0035980762 scopus 로고    scopus 로고
    • Gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells
    • Colquhoun A, Schumacher RI. Gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. Biochim Biophys Acta 2001;1533:207-219.
    • (2001) Biochim Biophys Acta , vol.1533 , pp. 207-219
    • Colquhoun, A.1    Schumacher, R.I.2
  • 8
    • 0034962169 scopus 로고    scopus 로고
    • Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo
    • Latham P, Lund EK, Brown JC et al. Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo. Gut 2001;49:97-105.
    • (2001) Gut , vol.49 , pp. 97-105
    • Latham, P.1    Lund, E.K.2    Brown, J.C.3
  • 9
    • 0036694927 scopus 로고    scopus 로고
    • Eicosapentaenoic acid promotes apoptosis in Ramos cells via activation of caspase-3 and -9
    • Heimli H, Giske C, Naderi S et al. Eicosapentaenoic acid promotes apoptosis in Ramos cells via activation of caspase-3 and -9. Lipids 2002;37:797-802.
    • (2002) Lipids , vol.37 , pp. 797-802
    • Heimli, H.1    Giske, C.2    Naderi, S.3
  • 10
    • 0037455987 scopus 로고    scopus 로고
    • Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: Involvement of lipoxygenase-derived metabolites and p38 MAPK pathway
    • Ait-Said F, Elalamy I, Werts C et al. Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta 2003;1631:77-84.
    • (2003) Biochim Biophys Acta , vol.1631 , pp. 77-84
    • Ait-Said, F.1    Elalamy, I.2    Werts, C.3
  • 11
    • 0033392868 scopus 로고    scopus 로고
    • Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29
    • Clarke RG, Lund EK, Latham P et al. Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29. Lipid 1999;34:1287-1295.
    • (1999) Lipid , vol.34 , pp. 1287-1295
    • Clarke, R.G.1    Lund, E.K.2    Latham, P.3
  • 12
    • 0025764152 scopus 로고
    • Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis
    • Cave WT Jr. Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis. FASEB J 1991;5:2160-2166.
    • (1991) FASEB J , vol.5 , pp. 2160-2166
    • Cave Jr., W.T.1
  • 13
    • 0035903132 scopus 로고    scopus 로고
    • Dual action of eicosapentaenoic acid in hepatoma cells: Up-regulation of metabolic action of insulin and inhibition of cell proliferation
    • Murata M, Kaji H, Iida K et al. Dual action of eicosapentaenoic acid in hepatoma cells: up-regulation of metabolic action of insulin and inhibition of cell proliferation. J Biol Chem 2001;276:31422-31428.
    • (2001) J Biol Chem , vol.276 , pp. 31422-31428
    • Murata, M.1    Kaji, H.2    Iida, K.3
  • 14
    • 0037906490 scopus 로고    scopus 로고
    • Mutation of p53 in recurrent hepatocellular carcinoma and its association with the expression of ZBP-89
    • Chen GG, Merchant JL, Lai PB et al. Mutation of p53 in recurrent hepatocellular carcinoma and its association with the expression of ZBP-89. Am J Pathol 2003;162:1823-1829.
    • (2003) Am J Pathol , vol.162 , pp. 1823-1829
    • Chen, G.G.1    Merchant, J.L.2    Lai, P.B.3
  • 15
    • 0034098493 scopus 로고    scopus 로고
    • The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma
    • Ito Y, Monden M, Takeda T et al. The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma. Br J Cancer 2000;82:1211-1217.
    • (2000) Br J Cancer , vol.82 , pp. 1211-1217
    • Ito, Y.1    Monden, M.2    Takeda, T.3
  • 16
    • 0035079863 scopus 로고    scopus 로고
    • Expression of Fas and Fas-related molecules in human hepatocellular carcinoma
    • Lee SH, Shin MS, Lee HS et al. Expression of Fas and Fas-related molecules in human hepatocellular carcinoma. Hum Pathol 2001;32:250-256.
    • (2001) Hum Pathol , vol.32 , pp. 250-256
    • Lee, S.H.1    Shin, M.S.2    Lee, H.S.3
  • 17
    • 0032977041 scopus 로고    scopus 로고
    • Cancer therapy based on p53
    • McCormick F. Cancer therapy based on p53. Cancer J Sci Am 1999;5:139-144.
    • (1999) Cancer J Sci Am , vol.5 , pp. 139-144
    • McCormick, F.1
  • 18
    • 0030966954 scopus 로고    scopus 로고
    • Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity
    • Micheau O, Solary E, Hammann A et al. Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity. J Natl Cancer Inst 1997;89:783-789.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 783-789
    • Micheau, O.1    Solary, E.2    Hammann, A.3
  • 19
    • 0012962781 scopus 로고    scopus 로고
    • Defective apoptosis and tumorigenesis: Role of p53 mutation and Fas/FasL system dysregulation
    • Cappello F, Bellafiore M, Palma A et al. Defective apoptosis and tumorigenesis: role of p53 mutation and Fas/FasL system dysregulation. Eur J Histochem 2002;46:199-208.
    • (2002) Eur J Histochem , vol.46 , pp. 199-208
    • Cappello, F.1    Bellafiore, M.2    Palma, A.3
  • 20
    • 0018718742 scopus 로고
    • Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line
    • Aden DP, Fogel A, Plotkin S et al. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 1979;228:615-616.
    • (1979) Nature , vol.228 , pp. 615-616
    • Aden, D.P.1    Fogel, A.2    Plotkin, S.3
  • 21
    • 0028300183 scopus 로고
    • Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis
    • Ponchel F, Puisieux A, Tabone E et al. Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis. Cancer Res 1994;54:2064-2068.
    • (1994) Cancer Res , vol.54 , pp. 2064-2068
    • Ponchel, F.1    Puisieux, A.2    Tabone, E.3
  • 22
    • 0021347915 scopus 로고
    • Phenotypical stability of a human hepatoma cell line, Huh-7, in long-term culture with chemically defined medium
    • Nakabayashi H, Taketa K, Yamane T et al. Phenotypical stability of a human hepatoma cell line, Huh-7, in long-term culture with chemically defined medium. Gann 1984;75:151-158.
    • (1984) Gann , vol.75 , pp. 151-158
    • Nakabayashi, H.1    Taketa, K.2    Yamane, T.3
  • 23
    • 0027207612 scopus 로고
    • p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines
    • Hsu IC, Tokiwa T, Bennett W et al. p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines. Carcinogenesis 1993;14:987-992.
    • (1993) Carcinogenesis , vol.14 , pp. 987-992
    • Hsu, I.C.1    Tokiwa, T.2    Bennett, W.3
  • 24
    • 0031053210 scopus 로고    scopus 로고
    • Differential effects of polyunsaturated fatty acids on chemosensitivity of NIH3T3 cells and its transformants
    • Tsai WS, Nagawa H, Muto T. Differential effects of polyunsaturated fatty acids on chemosensitivity of NIH3T3 cells and its transformants. Int J Cancer 1997;70:357-361.
    • (1997) Int J Cancer , vol.70 , pp. 357-361
    • Tsai, W.S.1    Nagawa, H.2    Muto, T.3
  • 25
    • 0024407164 scopus 로고
    • Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
    • Cazenave C, Stein CA, Loreau N et al. Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res 1989;17:4255-4273.
    • (1989) Nucleic Acids Res , vol.17 , pp. 4255-4273
    • Cazenave, C.1    Stein, C.A.2    Loreau, N.3
  • 26
    • 0030019570 scopus 로고    scopus 로고
    • Anti-tumor promotion with food phytochemicals: A strategy for cancer chemoprevention
    • Murakami A, Ohigashi H, Koshimizu K. Anti-tumor promotion with food phytochemicals: a strategy for cancer chemoprevention. Biosci Biotechnol Biochem 1996;60:1-8.
    • (1996) Biosci Biotechnol Biochem , vol.60 , pp. 1-8
    • Murakami, A.1    Ohigashi, H.2    Koshimizu, K.3
  • 27
    • 0026719044 scopus 로고
    • Increased cytotoxicity of polyunsaturated fatty acids on human tumoral B and T-cell lines compared with normal lymphocytes
    • Anel J, Naval J, Desportes B et al. Increased cytotoxicity of polyunsaturated fatty acids on human tumoral B and T-cell lines compared with normal lymphocytes. Leukemia 1992;6:680-688.
    • (1992) Leukemia , vol.6 , pp. 680-688
    • Anel, J.1    Naval, J.2    Desportes, B.3
  • 28
    • 0030902312 scopus 로고    scopus 로고
    • High levels of dietary arachidonic acid triglyceride exhibit no subchronic toxicity in rats
    • Koskelo EK, Boswell K, Carl L et al. High levels of dietary arachidonic acid triglyceride exhibit no subchronic toxicity in rats. Lipids 1997;32:397-405.
    • (1997) Lipids , vol.32 , pp. 397-405
    • Koskelo, E.K.1    Boswell, K.2    Carl, L.3
  • 29
    • 0037191503 scopus 로고    scopus 로고
    • Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid
    • Kokura S, Nakagawa T, Hara Y et al. Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid. Cancer Lett 2002;185:139-144.
    • (2002) Cancer Lett , vol.185 , pp. 139-144
    • Kokura, S.1    Nakagawa, T.2    Hara, Y.3
  • 30
    • 0028867236 scopus 로고
    • The clinical significance of p53 gene mutation in hepatocellular carcinomas from Japan
    • Hayashi H, Sugio K, Matsumata T et al. The clinical significance of p53 gene mutation in hepatocellular carcinomas from Japan. Hepatology 1995;22:1702-1707.
    • (1995) Hepatology , vol.22 , pp. 1702-1707
    • Hayashi, H.1    Sugio, K.2    Matsumata, T.3
  • 31
    • 0033755364 scopus 로고    scopus 로고
    • Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection?
    • Jeng KS, Sheen IS, Chen BF et al. Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection? Arch Surg 2000;135:1329-1333.
    • (2000) Arch Surg , vol.135 , pp. 1329-1333
    • Jeng, K.S.1    Sheen, I.S.2    Chen, B.F.3
  • 32
    • 0034718770 scopus 로고    scopus 로고
    • Chemotherapeutic drug, Adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells
    • Yun C, Lee JH, Park H et al. Chemotherapeutic drug, Adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells. Oncogene 2000;19:5163-5172.
    • (2000) Oncogene , vol.19 , pp. 5163-5172
    • Yun, C.1    Lee, J.H.2    Park, H.3
  • 33
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 34
    • 0029003501 scopus 로고
    • Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
    • Owen-Schaub LB, Zhang W, Cusack JC et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 1995;15:3032-3040.
    • (1995) Mol Cell Biol , vol.15 , pp. 3032-3040
    • Owen-Schaub, L.B.1    Zhang, W.2    Cusack, J.C.3
  • 35
    • 0031743648 scopus 로고    scopus 로고
    • p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
    • Muller M, Wilder S, Bannasch D et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998;188:2033-2045.
    • (1998) J Exp Med , vol.188 , pp. 2033-2045
    • Muller, M.1    Wilder, S.2    Bannasch, D.3
  • 36
    • 0037379914 scopus 로고    scopus 로고
    • Fas-mediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143
    • Li Y, Raffo AJ, Drew L et al. Fas-mediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143. Cancer Res 2003;63:1527-1533.
    • (2003) Cancer Res , vol.63 , pp. 1527-1533
    • Li, Y.1    Raffo, A.J.2    Drew, L.3
  • 37
    • 0042337367 scopus 로고    scopus 로고
    • Mutant p53 gain of function: Repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants
    • Zalcenstein A, Stambolsky P, Weisz L et al. Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene 2003;22:5667-5676.
    • (2003) Oncogene , vol.22 , pp. 5667-5676
    • Zalcenstein, A.1    Stambolsky, P.2    Weisz, L.3
  • 38
    • 0033748796 scopus 로고    scopus 로고
    • p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines
    • Petak I, Tillman DM, Houghton JA. p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines. Clin Cancer Res 2000;6:4432-4441.
    • (2000) Clin Cancer Res , vol.6 , pp. 4432-4441
    • Petak, I.1    Tillman, D.M.2    Houghton, J.A.3
  • 39
    • 0034721094 scopus 로고    scopus 로고
    • Involvement of p53 and interleukin 3 in the up-regulation of CD95 (APO-1/Fas) by X-ray irradiation
    • Gutierrez del Arroyo A, Gil-Lamagniere C, Lazaro I et al. Involvement of p53 and interleukin 3 in the up-regulation of CD95 (APO-1/Fas) by X-ray irradiation. Oncogene 2000;19:3647-3655.
    • (2000) Oncogene , vol.19 , pp. 3647-3655
    • Gutierrez Del Arroyo, A.1    Gil-Lamagniere, C.2    Lazaro, I.3
  • 40
    • 0034899819 scopus 로고    scopus 로고
    • Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants
    • Heimli H, Finstad HS, Drevon CA. Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants. Lipids 2001;36:613-621.
    • (2001) Lipids , vol.36 , pp. 613-621
    • Heimli, H.1    Finstad, H.S.2    Drevon, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.