Differential protective effects of palmitoleic acid and cAMP on caspase activation and cell viability in pancreatic β-cells exposed to palmitate

Apoptosis

Volumn 11, Issue 7, 2006, Pages 1231-1238

  Welters, Hannah J ^a   Diakogiannaki, Eleftheria ^a   Mordue, J Mark ^a   Tadayyon, Moh ^b   Smith, Stephen A ^c   Morgan, Noel G ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Apoptosis; BRIN BD11 cells; Forskolin; Islets of Langerhans; Mono unsaturated fatty acid; Palmitoleate

Indexed keywords

CASPASE; CYCLIC AMP; FATTY ACID; MONOUNSATURATED FATTY ACID; PALMITIC ACID; PALMITOLEIC ACID;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

1-METHYL-3-ISOBUTYLXANTHINE; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIC AMP; CYSTEINE PROTEINASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, MONOUNSATURATED; FORSKOLIN; INSULIN-SECRETING CELLS; PALMITIC ACID;

EID: 33745854213     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-7450-7     Document Type: Article

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