Mono and bivalent binding of a scFv and covalent diabody to murine laminin-1 using radioiodinated proteins and SPR measurements: Effects on tissue retention in vivo

Journal of Immunological Methods

Volumn 313, Issue 1-2, 2006, Pages 149-160

  Huang, Bao cheng ^a   Davern, Sandra ^b   Kennel, Stephen J ^a,b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

Author keywords

Binding constant; Diabody; Laminin; scFv; Tumor

Indexed keywords

AMINO ACID; CYSTEINE; IODINE 125; LAMININ 1; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCULATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION; DISULFIDE BOND; FEMALE; KIDNEY; KINETICS; MOUSE; MUSCLE; NONHUMAN; PHAGE DISPLAY; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; RADIOIODINATION; RAT; SCID MOUSE; SOLID; SURFACE PLASMON RESONANCE; TUMOR;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; CELL LINE, TUMOR; FEMALE; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; KIDNEY; KINETICS; LAMININ; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; NEOPLASMS; PICHIA; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION;

MURINAE; PICHIA PASTORIS;

EID: 33745727434     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2006.04.006     Document Type: Article

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