Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris

Protein Engineering

Volumn 10, Issue 10, 1997, Pages 1221-1225

  Fitzgerald, Kevin ^a,b   Holliger, Philipp ^b   Winter, Greg ^b,c  

^a MEDIMMUNE LTD   (United Kingdom)

^b MRC CENTRE FOR PROTEIN ENGINEERING   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

CEA; Diabodies; Disulphide crosslinks; Pichia; Tumour imaging

Indexed keywords

ANTIBODY; CARCINOEMBRYONIC ANTIGEN; CYSTEINE; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; POLYPEPTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENDOMYCETALES; ESCHERICHIA COLI; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN STABILITY; TUMOR; TUMOR XENOGRAFT;

ANIMALIA; ESCHERICHIA COLI; MUS MUSCULUS; PICHIA; PICHIA PASTORIS; SACCHAROMYCETALES;

EID: 0031441221     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.10.1221     Document Type: Article

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