SCOPUS 정보 검색 플랫폼

Volumn 60, Issue 22, 2000, Pages 6434-6440

Targeting of bivalent anti-ErbB2 diabody antibody fragments to tumor cells is independent of the intrinsic antibody affinity

(4) Nielsen, Ulrik B a Adams, Gregory P b Weiner, Louis M b Marks, James D a

a UNIVERSITY OF CALIFORNIA (United States)

b FOX CHASE CANCER CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOLOGY; DIMERIZATION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MOUSE; NONHUMAN; ONCOGENE NEU; PRIORITY JOURNAL; PROTEIN DOMAIN; TUMOR LOCALIZATION;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIBODY AFFINITY; FEMALE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; KINETICS; MICE; MICE, INBRED ICR; MICE, SCID; OVARIAN NEOPLASMS; RECEPTOR, ERBB-2; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0033708769 PISSN: 00085472 EISSN: None Source Type: Journal
DOI: None Document Type: Article

Times cited : (109)

References (29)

1
- 0004198722
- Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
- (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5879-5883
- Huston, J.S.¹ Levinson, D.² Mudgett-Hunter, M.³ Tai, M.S.⁴ Novotny, J.⁵ Margolies, M.N.⁶ Ridge, R.J.⁷ Bruccoleri, R.E.⁸ Haber, E.⁹ Crea, R.¹⁰ Oppermann, H.¹¹

2
- 0024293979
- Single-chain antigen-binding proteins
- (1988) Science (Washington DC) , vol.242 , pp. 423-426
- Bird, R.E.¹ Hardman, K.D.² Jacobson, J.W.³ Johnson, S.⁴ Kaufman, B.M.⁵ Lee, S.M.⁶ Lee, T.⁷ Pope, S.H.⁸ Riordan, G.S.⁹ Whitlow, M.¹⁰

3
- 9544250404
- Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
- (1996) Nat. Med. , vol.2 , pp. 979-984
- Begent, R.H.¹ Verhaar, M.J.² Chester, K.A.³ Casey, J.L.⁴ Green, A.J.⁵ Napier, M.P.⁶ Hope-Stone, L.D.⁷ Cushen, N.⁸ Keep, P.A.⁹ Johnson, C.J.¹⁰ Hawkins, R.E.¹¹ Hilson, A.J.¹² Robson, L.¹³

4
- 0025362523
- In vivo tumor targeting of a recombinant single-chain antigen-binding protein
- (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1191-1197
- Colcher, D.¹ Bird, R.² Roselli, M.³ Hardman, K.D.⁴ Johnson, S.⁵ Pope, S.⁶ Dodd, S.W.⁷ Pantoliano, M.W.⁸ Milenic, D.E.⁹ Schlom, J.¹⁰

5
- 0027303686
- Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv
- (1993) Cancer Res. , vol.53 , pp. 4026-4034
- Adams, G.P.¹ McCartney, J.E.² Tai, M.S.³ Oppermann, H.⁴ Huston, J.S.⁵ Stafford, W.F.D.⁶ Bookman, M.A.⁷ Fand, I.⁸ Houston, L.L.⁹ Weiner, L.M.¹⁰

6
- 0026684815
- Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
- (1992) Cancer Res. , vol.52 , pp. 3402-3408
- Yokota, T.¹ Milenic, D.E.² Whitlow, M.³ Schlom, J.⁴

7
- 0032422140
- Pharmacokinetics and biodistribution of genetically-engineered antibodies
- (1998) Q. J. Nucl. Med. , vol.42 , pp. 225-241
- Colcher, D.¹ Pavlinkova, G.² Beresford, G.³ Booth, B.J.⁴ Choudhury, A.⁵ Batra, S.K.⁶

8
- 0026327378
- Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
- (1991) Cancer Res. , vol.51 , pp. 6363-6371
- Milenic, D.E.¹ Yokota, T.² Filpula, D.R.³ Finkelman, M.A.⁴ Dodd, S.W.⁵ Wood, J.F.⁶ Whitlow, M.⁷ Snoy, P.⁸ Schlom, J.⁹

9
- 0032006660
- Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies
- (1998) Cancer Res. , vol.58 , pp. 485-490
- Adams, G.P.¹ Schier, R.² Marshall, K.³ Wolf, E.J.⁴ McCall, A.M.⁵ Marks, J.D.⁶ Weiner, L.M.⁷

10
- 0026528230
- Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
- (1992) Biochemistry , vol.31 , pp. 1579-1584
- Pack, P.¹ Pluckthun, A.²

11
- 0029890636
- Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
- (1996) Cancer Res. , vol.56 , pp. 3055-3061
- Hu, S.¹ Shively, L.² Raubitschek, A.³ Sherman, M.⁴ Williams, L.E.⁵ Wong, J.Y.⁶ Shively, J.E.⁷ Wu, A.M.⁸

12
- 0029918942
- Tumor localization of anti-CEA single-chain Fvs: Improved targeting by non-covalent dimers
- (1996) Immunotechnology , vol.2 , pp. 21-36
- Wu, A.M.¹ Chen, W.² Raubitschek, A.³ Williams, L.E.⁴ Neumaier, M.⁵ Fischer, R.⁶ Hu, S.Z.⁷ Odom-Maryon, T.⁸ Wong, J.Y.⁹ Shively, J.E.¹⁰

13
- 0028074723
- Multivalent Fvs: Characterization of single-chain Fv oligomers and preparation of a bispecific Fv
- (1994) Protein Eng. , vol.7 , pp. 1017-1026
- Whitlow, M.¹ Filpula, D.² Rollence, M.L.³ Feng, S.L.⁴ Wood, J.F.⁵

14
- 0027197493
- Diabodies: Small bivalent and bispecific antibody fragments
- (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6444-6448
- Holliger, P.¹ Prospero, T.² Winter, G.³

15
- 0028774708
- Crystal structure of a diabody, a bivalent antibody fragment
- (1994) Structure , vol.2 , pp. 1217-1226
- Perisic, O.¹ Webb, P.A.² Holliger, P.³ Winter, G.⁴ Williams, R.L.⁵

16
- 0031942906
- Prolonged in vivo turnout retention of a human diabody targeting the extracellular domain of human HER2/neu
- (1998) Br. J. Cancer , vol.77 , pp. 1405-1412
- Adams, G.P.¹ Schier, R.² McCall, A.M.³ Crawford, R.S.⁴ Wolf, E.J.⁵ Weiner, L.M.⁶ Marks, J.D.⁷

17
- 0029294084
- In vitro and in vivo characterization of a human anti-c-erbB-2 single-chain Fv isolated from a filamentous phage antibody library
- (1995) Immunotechnology , vol.1 , pp. 73-81
- Schier, R.¹ Marks, J.D.² Wolf, E.J.³ Apell, G.⁴ Wong, C.⁵ McCartney, J.E.⁶ Bookman, M.A.⁷ Huston, J.S.⁸ Houston, L.L.⁹ Weiner, L.M.¹⁰ Adams, G.P.¹¹

18
- 0030575802
- Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
- (1996) J. Mol. Biol. , vol.263 , pp. 551-567
- Schier, R.¹ McCall, A.² Adams, G.P.³ Marshall, K.W.⁴ Merritt, H.⁵ Yim, M.⁶ Crawford, R.S.⁷ Weiner, L.M.⁸ Marks, C.⁹ Marks, J.D.¹⁰

19
- 0029361891
- Mapping the detailed specificity of a calcium-dependent monoclonal antibody through the use of soluble positional scanning combinatorial libraries: Identification of potent calcium-independent antigens
- (1995) Mol. Divers. , vol.1 , pp. 21-28
- Pinilla, C.¹ Buencamino, J.² Appel, J.R.³ Hopp, T.P.⁴ Houghten, R.A.⁵

20
- 0007000556
- Expression of single-chain Fv-Fc fusions in Pichia pastoris
- in press
- (2000) J. Immunol. Methods
- Powers, D.B.¹ Amersdorfer, P.² Poul, M.A.³ Nielsen, U.B.⁴ Shalaby, M.R.⁵ Adams, G.P.⁶ Weiner, L.M.⁷ Marks, J.D.⁸

21
- 0031025006
- Determination of the binding affinity of an anti-CD34 single-chain antibody using a novel, flow cytometry based assay
- (1997) J. Immunol. Methods , vol.201 , pp. 223-231
- Benedict, C.A.¹ MacKrell, A.J.² Anderson, W.F.³

22
- 0029866268
- NCOMP - A windows-based computer program for noncompartmental analysis of pharmacokinetic data
- (1996) J. Pharm. Sci. , vol.85 , pp. 393-395
- Laub, P.B.¹ Gallo, J.M.²

23
- 0028040317
- The biologic window for chimeric L6 radioimmunotherapy
- (1994) Cancer (Phila.) , vol.73 , pp. 1023-1032
- DeNardo, S.J.¹ Mirick, G.R.² Kroger, L.A.³ O'Grady, L.F.⁴ Erickson, K.L.⁵ Yuan, A.⁶ Lamborn, K.R.⁷ Hellstrom, I.⁸ Hellstrom, K.E.⁹ DeNardo, G.L.¹⁰

24
- 0032870332
- Pharmacokinetics and biodistribution of engineered single-chain antibody constructs of MAb CC49 in colon carcinoma xenografts
- (1999) J. Nucl. Med. , vol.40 , pp. 1536-1546
- Pavlinkova, G.¹ Beresford, G.W.² Booth, B.J.³ Batra, S.K.⁴ Colcher, D.⁵

25
- 0026705890
- Effect of bivalent interaction upon apparent antibody affinity: Experimental confirmation of theory using fluorescence photobleaching and implications for antibody binding assays
- (1992) Cancer Res. , vol.52 , pp. 4157-4167
- Kaufman, E.N.¹ Jain, R.K.²

26
- 0015313012
- The influence of polyvalency on the binding properties of antibodies
- (1972) Immunochemistry , vol.9 , pp. 341-357
- Crothers, D.M.¹ Metzger, H.²

27
- 0025014962
- Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors
- (1990) Cancer Res. , vol.50 , pp. 814s-819s
- Jain, R.K.¹

28
- 0024433856
- Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2, and Fab in tumors
- (1989) Cancer Res. , vol.49 , pp. 5656-5663
- Fujimori, K.¹ Covell, D.G.² Fletcher, J.E.³ Weinstein, J.N.⁴

29
- 0033555628
- Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
- (1999) Cancer Res. , vol.59 , pp. 347-352
- Viti, F.¹ Tarli, L.² Giovannoni, L.³ Zardi, L.⁴ Neri, D.⁵

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