General and versatile entry to 4,5-fused polycyclic imidazolones systems. Use of the tandem transposition/π-cyclization of N-acyliminium species

Journal of Organic Chemistry

Volumn 71, Issue 14, 2006, Pages 5303-5311

  Pesquet, Anthony ^a   Daïch, Adam ^a   Van Hijfte, Luc ^b  

^a UNIVERSITÉ DU HAVRE   (France)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDANTOIN RING; REGIOSELECTIVE REDUCTION; SPIROHYDANTOIN; TANDEM TRANSPOSITION;

ALKYLATION; NITROGEN; POSITIVE IONS; REACTION KINETICS; REDUCTION; SYNTHESIS (CHEMICAL);

KETONES;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 [4 (4 FLUOROPHENYL) 1 (3 PHENYLPROPYL) 5 (4 PYRIDINYL) 1H IMIDAZOL 2 YL] 3 BUTYN 1 OL; 5 (4 PYRIDINYL) 4 (4 FLUOROPHENYL) 1 (3 MORPHOLINOPROPYL)IMIDAZOLE; 5 (4 PYRIDINYL) 4 (4 FLUOROPHENYL) 1 (4 PIPERIDINYL)IMIDAZOLE; CANNABINOID RECEPTOR AGONIST; HETEROCYCLIC COMPOUND; HYDANTOIN DERIVATIVE; IMIDAZOLE DERIVATIVE; KETONE; L 790070; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; ML 3163; ML 3375; NITROGEN; SB 216995; SB 242235; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TEMPERATURE;

CYCLIZATION; IMIDAZOLES; KETONES; MOLECULAR STRUCTURE; POLYCYCLIC HYDROCARBONS, AROMATIC; STEREOISOMERISM;

EID: 33745714353     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060616s     Document Type: Article

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