Identification of regioisomers in a series of N-substituted pyridin-4-yl imidazole derivatives by regiospecific synthesis, GC/MS, and 1H NMR

Journal of Organic Chemistry

Volumn 68, Issue 11, 2003, Pages 4527-4530

  Wagner, Gerd K ^a,b   Kotschenreuther, Dunja ^a,c   Zimmermann, Werner ^a   Laufer, Stefan A ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b University of Bath   (United Kingdom)

^c ratiopharm GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHY; ENZYME INHIBITION; ISOMERS; NITROGEN COMPOUNDS; SPECTROSCOPY; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

REGIOSPECIFIC SYNTHESIS;

ORGANIC COMPOUNDS;

ANTIINFLAMMATORY AGENT; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PYRIDIN 4 YLIMIDAZOLE DERIVATIVE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CYTOKINE RELEASE; DRUG SYNTHESIS; GAS CHROMATOGRAPHY; ISOMER; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

ALKYLATION; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE SPECTROSCOPY; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENETHYLAMINES; PYRIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038146839     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo026619w     Document Type: Article

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