Synthesis and antibacterial activity of novel C12 ethyl ketolides

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 16, 2006, Pages 5592-5604

  Burger, Matthew T ^a   Hiebert, Christy ^a   Seid, Mehran ^a   Chu, Daniel T ^a   Barker, Lynn ^a   Langhorne, Mike ^a   Shawar, Ribhi ^a   Kidney, Jolene ^a   Desai, Manoj C ^a   Plattner, Jacob J ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antibiotic; Antiinfective; Ketolide; Ketolide antibiotic; Macrolide; Macrolide antibiotic

Indexed keywords

CLARITHROMYCIN; ERYTHROMYCIN; KETOLIDE; TELITHROMYCIN;

ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; IN VIVO STUDY; LD 50; METHYLATION; MOUSE; NONHUMAN; RIBOSOME; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANTI-BACTERIAL AGENTS; ERYTHROMYCIN; KETOLIDES; METHYLATION; MICE; MICROBIAL SENSITIVITY TESTS; RESPIRATORY TRACT INFECTIONS; RIBOSOMES; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

STREPTOCOCCUS PNEUMONIAE;

EID: 33745610459     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.04.032     Document Type: Article

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