Anhydrolide macrolides. 1. Synthesis and antibacterial activity of 2,3- anhydro-6-O-methyl 11,12-carbamate erythromycin A analogues

Journal of Medicinal Chemistry

Volumn 41, Issue 10, 1998, Pages 1651-1659

  Elliott, Richard L ^a,b   Pireh, Daisy ^a   Griesgraber, George ^a   Nilius, Angela M ^a   Ewing, Patty J ^a   Bui, Mai Ha ^a   Raney, Patti M ^a   Flamm, Robert K ^a   Kim, Ki ^a   Henry, Rodger F ^a   Chu, Daniel T W ^a   Plattner, Jacob J ^a   Or, Yat Sun ^a  

^a ABBOTT LABORATORIES   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 ANHYDRO 6 O METHYL 11,12 CARBAMATE ERYTHROMYCIN A; AZITHROMYCIN; CLARITHROMYCIN; ERYTHROMYCIN DERIVATIVE; MACROLIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RIBOSOME SUBUNIT; SOFT TISSUE INFECTION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; CARBAMATES; CLARITHROMYCIN; COLONY COUNT, MICROBIAL; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, MICROBIAL; DRUG RESISTANCE, MULTIPLE; ERYTHROMYCIN; HAEMOPHILUS INFLUENZAE; MACROLIDES; MICE; MOLECULAR CONFORMATION; PNEUMOCOCCAL INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRGINIAMYCIN;

EID: 6744251737     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970547x     Document Type: Article

References (25)

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