Conformational analysis of ketolide, conformations of RU 004 in solution and bound to bacterial ribosomes

Journal of Medicinal Chemistry

Volumn 41, Issue 18, 1998, Pages 3373-3386

  Bertho, Gildas ^a   Gharbi Benarous, Josyane ^a   Delaforge, Marcel ^a   Lang, Catherine ^b   Parent, Annick ^b   Girault, Jean Pierre ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HMR 3004; KETOLIDE; MACROLIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; DRUG CONFORMATION; DRUG STABILITY; NUCLEAR OVERHAUSER EFFECT; RIBOSOME;

ANTI-BACTERIAL AGENTS; BACTERIA; BUFFERS; CRYSTALLOGRAPHY, X-RAY; MACROLIDES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; RIBOSOMES; SOLUTIONS; TEMPERATURE;

EID: 0032572826     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970852i     Document Type: Article

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