Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 21, 1999, Pages 3075-3080

  Denis, Alexis ^a   Agouridas, Constantin ^b   Auger, Jean Michel ^a   Benedetti, Yannick ^a   Bonnefoy, Alain ^c   Bretin, François ^a   Chantot, Jean François ^c   Dussarat, Arlette ^a   Fromentin, Claude ^a   Gouin D'Ambrières, Solange ^a   Lachaud, Sylvette ^a   Laurin, Patrick ^a   Le Martret, Odile ^a   Loyau, Véronique ^a   Tessot, Nicole ^a   Pejac, Jean Marie ^a   Perron, Sébastien ^a  

^a Medicinal Chemistry   (France)

^b Core Research Functions ^*  (France)

^c Hoechst Marion Roussel   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TELITHROMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DISEASE MODEL; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG POTENCY; DRUG SENSITIVITY; DRUG SYNTHESIS; ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; ERYTHROMYCIN; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HAEMOPHILUS INFLUENZAE; KETOLIDES; MACROLIDES; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE;

ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

EID: 0033229837     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00534-X     Document Type: Article

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