Interaction analysis between 5-HTTLPR and TNFA -238/-308 polymorphisms in schizophrenia

Journal of Neural Transmission

Volumn 113, Issue 7, 2006, Pages 887-897

  Pae, C U ^a   Serretti, A ^b   Artioli, P ^b   Kim, T S ^a   Kim, J J ^a   Lee, C U ^a   Lee, S J ^a   Paik, I H ^a   Lee, C ^a  

^a The Catholic University of Korea   (South Korea)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

5 HTTLPR; Antipsychotic treatment response; Korean; Psychopathology; Schizophrenia; TNFA 238 308 polymorphism

Indexed keywords

CHLORPROMAZINE; DNA; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; SEROTONIN TRANSPORTER; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ASIAN; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; SCORING SYSTEM; SEROTONINERGIC SYSTEM; SUICIDE ATTEMPT; TREATMENT OUTCOME;

ADULT; AGE DISTRIBUTION; BRAIN; BRAIN CHEMISTRY; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENETIC TESTING; GENOTYPE; HUMANS; KOREA; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SCHIZOPHRENIA; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEX DISTRIBUTION; SYNAPTIC TRANSMISSION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745497143     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-005-0358-5     Document Type: Article

References (51)

1. American Psychiatric Association 1994 DSM-IV: Diagnostic and statistical manual of mental disorder 4 American Psychiatric Press Washington DC
2. MJ Arranz AA Bolonna J Munro CJ Curtis DA Collier RW Kerwin 2000 The serotonin transporter and clozapine response Mol Psychiatry 5 124 125
3. F Boin R Zanardini R Pioli CA Altamura M Maes M Gennarelli 2001 Association between -G308A tumor necrosis factor alpha gene polymorphism and schizophrenia Mol Psychiatry 6 79 82
4. KR Bonson JW Buckholtz DL Murphy 1996 Chronic administration of serotonergic antidepressants attenuates the subjective effects of LSD in humans Neuropsychopharmacology 14 425 436
5. PB Bradley G Engel W Feniuk JR Fozard PPA Humphrey DN Middlemiss EJ Mylecharane BP Richardson PR Saxena 1986 Proposal for the classification and nomenclature of functional receptors for 5-hydroxytryptamine Neuropharmacology 25 563 576
6. SA Chong WL Lee CH Tan AH Tay AO Chan EC Tan 2000 Attempted suicide and polymorphism of the serotonin transporter gene in Chinese patients with schizophrenia Psychiatr Res 97 101 106
7. S Duan Y Xu W Chen Z Liu T Guo J Gao L Bian Y Zhen X Li X Zhang Y Pan N Gu G Feng L He 2004 No association between the promoter variants of tumor necrosis factor alpha (TNF-alpha) and schizophrenia in Chinese Han population Neurosci Lett 366 139 143
8. AB Erbagci H Herken O Koyluoglu N Yilmaz M Tarakcioglu 2001 Serum IL-1beta, sIL-2R, IL-6, IL-8 and TNF-alpha in schizophrenic patients, relation with symptomatology and responsiveness to risperidone treatment Mediators Inflamm 10 109 115
9. MB First RL Spitzer M Gibbon JBW Williams 1997 Structured Clinical Interview for DSM-IV-Clinician Version (SCID-CV) American Psychiatric Press Washington DC
10. J Gelernter AJ Pakstis KK Kidd 1995 Linkage mapping of serotonin transporter protein gene SLC6A4 on choromosome 17 Hum Genet 95 677 680
11. RA Glennon 1990 Do classical hallucinogens act as 5-HT2 agonists or antagonists? Neuropsychopharmacology 3 509 517
12. DC Goff AW Brotman M Waites S [tmp] McCormick 1990 Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients Am J Psychiatry 147 492 494
13. M Hamone L Lanfumey S Mestikawy C Boni M Miquel F Bolanos L Schechter H Gozlan 1990 The main features of central 5-HT1 receptor Neuropsychopharmacology 3 349 360
14. HY Handoko DJ Nancarrow NK Hayward JU Ohaeri H Aghanwa JJ [tmp] McGrath DF Levinson C Johns MK Walters DA Nertney TN Srinivasan R Thara BJ Mowry 2003 Tumor necrosis factor haplotype analysis amongst schizophrenia probands from four distinct populations in the Asia-Pacific region Am J Med Genet B Neuropsychiatr Genet 121 1 6
15. R Hashimoto M Yoshida N Ozaki Y Yamanouchi N Iwata T Suzuki T Kitajima M Tatsumi K Kamijima H Kunugi 2004 Association analysis of the -308G>A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia J Neural Transm 111 217 221
16. A Heils A Teufel S Petri M Seemann D Bengel U Balling P Riederer KP Lesch 1995 Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene J Neural Transm (Gen Sect) 102 247 254
17. RJ Holden IS Pakula 1999 Tumor necrosis factor-alpha: is there a continuum of liability between stress, anxiety states and anorexia nervosa? Med Hypotheses 52 155 162
18. D Hranilovic J Stefulj S Schwab M Borrmann-Hassenbach M Albus B Jernej D Wildenauer 2004 Serotonin transporter promoter and intron 2 polymorphisms: relationship between allelic variants and gene expression Biol Psychiatry 55 1090 1094
19. R Kaiser B Muller-Oerlinghausen D Filler PB Tremblay A Berghofer I Roots J Brockmoller 2002 Correlation between serotonin uptake in human blood platelets with the 44-bp polymorphism and the 17-bp variable number of tandem repeat of the serotonin transporter Am J Med Genet 114 323 328
20. W Kaluza E Reuss S Grossmann R Hug RE Schopf PR Galle E Maerker-Hermann T Hoehler 2000 Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism J Invest Dermatol 114 1180 1183
21. SR Kay LA Opler JP Lindenmayer 1988 Reliability and validity of the positive and negative syndrome scale for schizophrenics Psychiatr Res 23 99 110
22. T Kubota J Fang Z Guan RA Brown JM Krueger 2001 Vagotomy attenuates tumor necrosis factor-alpha-induced sleep and EEG delta-activity in rats Am J Physiol Regul Integr Comp Physiol 280 R1213 R1220
23. KP Lesch D Bengel A Heils SZ Sabol BD Greenberg S Petri J Benjamin CR Muller DH Hamer DL Murphy 1996 Association of anxiety related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1527 1531
24. CM Lewis DF Levinson LH Wise LE DeLisi RE Straub I Hovatta 2003 Genome scan meta-analysis of schizophrenia and bipolar disorder, part II. Schizophrenia Am J Hum Genet 73 34 48
25. AK Malhotra D Goldman C Mazzanti A Clifton A Breier D Pickar 1998 A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics Mol Psychiatry 3 328 332
26. IV Meira-Lima AC Pereira GF Mota M Floriano F Araujo AJ Mansur JE Krieger H Vallada 2003 Analysis of a polymorphism in the promoter region of the tumor necrosis factor alpha gene in schizophrenia and bipolar disorder: further support for an association with schizophrenia Mol Psychiatry 8 718 720
27. JR Mendes de Oliveira PA Otto H Vallada V Lauriano H Elkis B Lafer L Vasquez V Gentil MR Passos Bueno M Zatz 1998 Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizophrenia Am J Med Genet 81 225 227
28. P Monteleone M Fabrazzo A Tortorella M Maj 1997 Plasma levels of interleukin-6 and tumor necrosis factor alpha in chronic schizophrenia: effects of clozapine treatment Psychiatr Res 71 11 17
29. R Mossner A Heils G Stober O Okladnova S Daniel KP Lesch 1998 Enhancement of serotonin transporter function by tumor necrosis factor alpha but not by interleukin-6 Neurochem Int 33 251 254
30. J Naudin C Capo B Giusano JL Mege JM Azorin 1997 A differential role for interleukin-6 and tumor necrosis factor-alpha in schizophrenia? Schizophr Res 26 227 233
31. L Naylor B Dean A Pereira A Mackinnon A Kouzmenko D Copolov 1998 No association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus Mol Med 4 671 674
32. CU Pae JH Chae WM Bahk H Han TY Jun KS Kim YS Kwon A Serretti 2003a Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population Psychiatry Clin Neurosci 57 399 403
33. CU Pae JJ Kim SJ Lee CU Lee C Lee IH Paik HR Park S Yang A Serretti 2003b Polymorphism of the serotonin transporter gene and symptomatic dimensions of schizophrenia in the Korean population Neuropsychobiology 47 182 186
34. A Reichenberg R Yirmiya A Schuld T Kraus M Haack A Morag T Pollmacher 2001 Cytokine-associated emotional and cognitive disturbances in humans Arch Gen Psychiatry 58 445 452
35. M Riedel H Kronig MJ Schwarz RR Engel KU Kuhn C Sikorski S Sokullu M Ackenheil HJ Moller N Muller 2002 No association between the G308A polymorphism of the tumor necrosis factor-alpha gene and schizophrenia Eur Arch Psychiatry Clin Neurosci 252 232 234
36. CJ Schmidt SM Sorensen JH Kehne AA Carr MG Palfreyman 1995 The role of 5-HT receptors in antipsychotic activity Life Sci 56 2209 2222
37. SG Schwab J Hallmayer M Albus B Lerer GN Eckstein M Borrmann 2000 A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6 Mol Psychiatry 5 638 649
38. SG Schwab S Mondabon M Knapp M Albus J Hallmayer M Borrmann-Hassenbach M Trixler M Gross TG Schulze M Rietschel B Lerer W Maier DB Wildenauer 2003 Association of tumor necrosis factor alpha gene -G308A polymorphism with schizophrenia Schizophr Res 65 19 25
39. PC Sham D Curtis 1995 Monte Carlo test for association between disease and alleles at highly polymorphic loci Ann Hum Genet 59 97 105
40. TV Shcherbatykh VD Golimbet VA Orlova VG Kaleda 2000 Polymorphism in the human serotonin transporter gene in endogenous psychoses Genetika 36 1712 1715
41. G Stober S Jatzke A Heils G Jungkunz E Fuchs M Knapp P Riederer KP Lesch 1998 Susceptibility for schizophrenia is not influenced by a functional insertion/deletion variant in the promoter of the serotonin transporter gene Eur Arch Psychiatry Clin Neurosci 248 82 86
42. RM Strieter SL Kunkel RC Bone 1993 Role of tumor necrosis factor-alpha in disease states and inflammation Crit Care Med 21 S447 S463
43. A Serretti M Catalano E Smeraldi 1999a Serotonin transporter gene is not associated with symptomatology of schizophrenia Schizophr Res 35 33 39
44. A Serretti F Macciardi C Cusin E Lattuada R Lilli D Di Bella M Catalano E Smeraldi 1999b No interaction of GABA(A) alpha-1 subunit and dopamine receptor D4 exon 3 genes in symptomatology of major psychoses Am J Med Genet 88 44 49
45. A Serretti R Lilli C Lorenzi E Lattuada C Cusin E Smeraldi 2002 Serotonin transporter gene (5-HTTLPR) and major psychoses Mol Psychiatry 7 95 99
46. EC Tan SA Chong CH Tan YY Teo K Peng R Mahendran 2003 Tumor necrosis factor-alpha gene promoter polymorphisms in chronic schizophrenia Biol Psychiatry 54 1205 1211
47. SJ Tsai CJ Hong YW Yu CH Lin HL Song HC Lai KH Yang 2000 Association study of a functional serotonin transporter gene polymorphism with schizophrenia, psychopathology and clozapine response Schizophr Res 44 177 181
48. SJ Tsai CJ Hong YW Yu CH Lin LL Liu 2003 No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine Schizophr Res 65 27 32
49. AG Wilson C Gordon FS di Giovine N de Vries LB van de Putte P Emery GH Duff 1994 A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha Eur J Immunol 24 191 195
50. X Xie J Ott 1993 Testing linkage disequilibrium between a disease gene and marker loci Am J Hum Genet [Suppl] 53 1107
51. JH Zhao 2004 2LD, Genecounting and HAP: computer programs for linkage disequilibrium analysis Bioinformatics 20 1325 1326