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Volumn 17, Issue 4, 2006, Pages 1503-1513

Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: A quantitative in vivo analysis by inhibition of PI3-kinase

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CHEMOATTRACTANT; CYCLIC AMP; CYCLIC GMP; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACTIN; CHEMOTACTIC FACTOR; CHROMONE DERIVATIVE; DAGA PROTEIN, DICTYOSTELIUM; ENZYME INHIBITOR; FUSED HETEROCYCLIC RINGS; GREEN FLUORESCENT PROTEIN; LATRUNCULIN A; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL; PHOSPHOINOSITIDE 3,4,5 TRIPHOSPHATE; PHOSPHOINOSITIDE-3,4,5-TRIPHOSPHATE; PROTOZOAL PROTEIN; THIAZOLE DERIVATIVE; THIAZOLIDINE DERIVATIVE;

EID: 33745384269     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E05-09-0825     Document Type: Article
Times cited : (91)

References (37)
  • 1
    • 0037009436 scopus 로고    scopus 로고
    • A novel cGMP-signaling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium
    • Bosgraaf, L., Russcher, H., Smith, J. L., Wessels, D., Soll, D. R., and Van Haastert, P.J.M. (2002). A novel cGMP-signaling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J. 21, 4560-4570.
    • (2002) EMBO J. , vol.21 , pp. 4560-4570
    • Bosgraaf, L.1    Russcher, H.2    Smith, J.L.3    Wessels, D.4    Soll, D.R.5    Van Haastert, P.J.M.6
  • 2
    • 0042019962 scopus 로고    scopus 로고
    • A model for cGMP signal transduction in Dictyostelium in perspective of 25 years of cGMP research
    • Bosgraaf, L., and Van Haastert, P. J. (2002). A model for cGMP signal transduction in Dictyostelium in perspective of 25 years of cGMP research. J. Muscle Res. Cell Motil. 23, 781-791.
    • (2002) J. Muscle Res. Cell Motil. , vol.23 , pp. 781-791
    • Bosgraaf, L.1    Van Haastert, P.J.2
  • 3
    • 0344796392 scopus 로고    scopus 로고
    • Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis
    • Chen, L., Janetopoulos, C., Huang, Y. E., Iijima, M., Borleis, J., and Devreotes, P. N. (2003). Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis. Mol. Biol. Cell 14, 5028-5037.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 5028-5037
    • Chen, L.1    Janetopoulos, C.2    Huang, Y.E.3    Iijima, M.4    Borleis, J.5    Devreotes, P.N.6
  • 4
    • 30044443294 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase
    • Comer, F. I., and Parent, C. A. (2006). Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase. Mol. Biol. Cell 17, 357-366.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 357-366
    • Comer, F.I.1    Parent, C.A.2
  • 5
    • 0037743735 scopus 로고    scopus 로고
    • Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
    • Devreotes, P., and Janetopoulos, C. (2003). Eukaryotic chemotaxis: distinctions between directional sensing and polarization. J. Biol. Chem. 278, 20445-20448.
    • (2003) J. Biol. Chem. , vol.278 , pp. 20445-20448
    • Devreotes, P.1    Janetopoulos, C.2
  • 6
    • 13544249968 scopus 로고    scopus 로고
    • In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis
    • Dormann, D., Weijer, G., Dowler, S., and Weijer, C. J. (2004). In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis. J. Cell Sci. 117, 6497-6509.
    • (2004) J. Cell Sci. , vol.117 , pp. 6497-6509
    • Dormann, D.1    Weijer, G.2    Dowler, S.3    Weijer, C.J.4
  • 7
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto, S., Meili, R., Lee, S., Parry, L., and Firtel, R. A. (2002). Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109, 611-623.
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 8
    • 0035858886 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium
    • Funamoto, S., Milan, K., Meili, R., and Firtel, R. A. (2001). Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium. J. Cell Biol. 153, 795-810.
    • (2001) J. Cell Biol. , vol.153 , pp. 795-810
    • Funamoto, S.1    Milan, K.2    Meili, R.3    Firtel, R.A.4
  • 9
    • 0038247883 scopus 로고    scopus 로고
    • Receptor mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells
    • Huang, Y. E., Iijima, M., Parent, C. A., Funamoto, S., Firtel, R. A., and Devreotes, P. N. (2003). Receptor mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Mol. Biol. Cell 14, 1913-1922.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1913-1922
    • Huang, Y.E.1    Iijima, M.2    Parent, C.A.3    Funamoto, S.4    Firtel, R.A.5    Devreotes, P.N.6
  • 10
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M., and Devreotes, P. (2002). Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109, 599-610.
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 11
    • 1942501586 scopus 로고    scopus 로고
    • Novel mechanism of PTEN regulation by its PIP2 binding motif is critical for chemotaxis
    • lijima, M., Huang, Y. E., Luo, H. R., Vazquez, F., and Devreotes, P. N. (2004). Novel mechanism of PTEN regulation by its PIP2 binding motif is critical for chemotaxis. J. Biol. Chem. 279, 16606-16613.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16606-16613
    • Lijima, M.1    Huang, Y.E.2    Luo, H.R.3    Vazquez, F.4    Devreotes, P.N.5
  • 12
    • 0028093610 scopus 로고
    • CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium
    • Insall, R., Kuspa, A., Lilly, P. J., Shaulsky, G., Levin, L. R., Loomis, W. F., and Devreotes, P. (1994). CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium. J. Cell Biol. 126, 1537-1545.
    • (1994) J. Cell Biol. , vol.126 , pp. 1537-1545
    • Insall, R.1    Kuspa, A.2    Lilly, P.J.3    Shaulsky, G.4    Levin, L.R.5    Loomis, W.F.6    Devreotes, P.7
  • 13
    • 16244377763 scopus 로고    scopus 로고
    • Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis
    • Janetopoulos, C., Borleis, J., Vazquez, F., Iijima, M., and Devreotes, P. (2005). Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis. Dev. Cell 8, 467-477.
    • (2005) Dev. Cell , vol.8 , pp. 467-477
    • Janetopoulos, C.1    Borleis, J.2    Vazquez, F.3    Iijima, M.4    Devreotes, P.5
  • 14
    • 2942687012 scopus 로고    scopus 로고
    • Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton
    • Janetopoulos, C., Ma, L., Devreotes, P. N., and Iglesias, P. A. (2004). Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 101, 8951-8956.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8951-8956
    • Janetopoulos, C.1    Ma, L.2    Devreotes, P.N.3    Iglesias, P.A.4
  • 15
    • 0014947106 scopus 로고
    • Microbiological assay of cyclic 3′,5′-AMP
    • Konijn, T. M. (1970). Microbiological assay of cyclic 3′,5′-AMP. Experientia 26, 367-369.
    • (1970) Experientia , vol.26 , pp. 367-369
    • Konijn, T.M.1
  • 16
    • 0037459060 scopus 로고    scopus 로고
    • Adenylyl cyclase localization regulates streaming during chemotaxis
    • Kriebel, P. W., Barr, V. A., and Parent, C. A. (2003). Adenylyl cyclase localization regulates streaming during chemotaxis. Cell 112, 549-560.
    • (2003) Cell , vol.112 , pp. 549-560
    • Kriebel, P.W.1    Barr, V.A.2    Parent, C.A.3
  • 18
    • 0041352963 scopus 로고    scopus 로고
    • Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42
    • Li, Z. et al. (2003). Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell 114, 215-227.
    • (2003) Cell , vol.114 , pp. 215-227
    • Li, Z.1
  • 19
    • 0037458725 scopus 로고    scopus 로고
    • A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum
    • Loovers, H. M., Veenstra, K., Snippe, H., Pesesse, X., Erneux, C., and van Haastert, P. J. (2003). A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum. J. Biol. Chem. 278, 5652-5658.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5652-5658
    • Loovers, H.M.1    Veenstra, K.2    Snippe, H.3    Pesesse, X.4    Erneux, C.5    Van Haastert, P.J.6
  • 20
    • 0010503979 scopus 로고
    • Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum
    • Mato, J. M., Losada, A., Nanjundiah, V., and Konijn, T. M. (1975). Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum. Proc. Natl. Acad. Sci. USA 72, 4991-4993.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 4991-4993
    • Mato, J.M.1    Losada, A.2    Nanjundiah, V.3    Konijn, T.M.4
  • 21
    • 1642328487 scopus 로고    scopus 로고
    • Making all the right moves: Chemotaxis in neutrophils and Dictyostelium
    • Parent, C. A. (2004). Making all the right moves: chemotaxis in neutrophils and Dictyostelium. Curr. Opin. Cell Biol. 16, 4-13.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 4-13
    • Parent, C.A.1
  • 22
    • 0032475863 scopus 로고    scopus 로고
    • G protein signaling events are activated at the leading edge of chemotactic cells
    • Parent, C. A., Blacklock, B. J., Froehlich, W. M., Murphy, D. B., and Devreotes, P. N. (1998). G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95, 81-91.
    • (1998) Cell , vol.95 , pp. 81-91
    • Parent, C.A.1    Blacklock, B.J.2    Froehlich, W.M.3    Murphy, D.B.4    Devreotes, P.N.5
  • 23
    • 0033617576 scopus 로고    scopus 로고
    • A cell's sense of direction
    • Parent, C. A., and Devreotes, P. N. (1999). A cell's sense of direction. Science 284, 765-770.
    • (1999) Science , vol.284 , pp. 765-770
    • Parent, C.A.1    Devreotes, P.N.2
  • 24
    • 0026504354 scopus 로고
    • Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development
    • Pitt, G. S., Milona, N., Borleis, J., Lin, K. C., Reed, R. R., and Devreotes, P. N. (1992). Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell 69, 305-315.
    • (1992) Cell , vol.69 , pp. 305-315
    • Pitt, G.S.1    Milona, N.2    Borleis, J.3    Lin, K.C.4    Reed, R.R.5    Devreotes, P.N.6
  • 25
    • 0344012465 scopus 로고    scopus 로고
    • Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia
    • Postma, M., Roelofs, J., Goedhart, J., Gadella, T.W.J., Visser, A.J.W.G., and Van Haastert, P.J.M. (2003). Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia. Mol. Biol. Cell 14, 5019-5027.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 5019-5027
    • Postma, M.1    Roelofs, J.2    Goedhart, J.3    Gadella, T.W.J.4    Visser, A.J.W.G.5    Van Haastert, P.J.M.6
  • 26
    • 3543062015 scopus 로고    scopus 로고
    • Sensitisation of Dictyostelium chemotaxis by PI3-kinase mediated self-organising signalling patches
    • Postma, M., Roelofs, J., Goedhart, J., Loovers, H. M., Visser, A.J.W.G., and Van Haastert, P.J.M. (2004). Sensitisation of Dictyostelium chemotaxis by PI3-kinase mediated self-organising signalling patches. J. Cell Sci. 117, 2925-2935.
    • (2004) J. Cell Sci. , vol.117 , pp. 2925-2935
    • Postma, M.1    Roelofs, J.2    Goedhart, J.3    Loovers, H.M.4    Visser, A.J.W.G.5    Van Haastert, P.J.M.6
  • 27
  • 29
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki, A. T., Chun, C., Takeda, K., and Firtel, R. A. (2004). Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167, 505-518.
    • (2004) J. Cell Biol. , vol.167 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 31
    • 0032933749 scopus 로고    scopus 로고
    • Computer-assisted three-dimensional reconstruction and motion analysis of living, crawling cells
    • Soll, D. R. (1999). Computer-assisted three-dimensional reconstruction and motion analysis of living, crawling cells. Comput. Med. Imaging Graph. 23, 3-14.
    • (1999) Comput. Med. Imaging Graph. , vol.23 , pp. 3-14
    • Soll, D.R.1
  • 32
    • 0019465923 scopus 로고
    • Adenosine 3′,5′-monophosphate waves in Dictyostelium discoideum: A demonstration by isotope dilution-fluorography
    • Tomchik, K. J., and Devreotes, P. N. (1981). Adenosine 3′,5′-monophosphate waves in Dictyostelium discoideum: a demonstration by isotope dilution-fluorography. Science 212, 443-446.
    • (1981) Science , vol.212 , pp. 443-446
    • Tomchik, K.J.1    Devreotes, P.N.2
  • 33
    • 0036308458 scopus 로고    scopus 로고
    • Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
    • Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G., and Bourne, H. R. (2002). Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4, 513-518.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 513-518
    • Wang, F.1    Herzmark, P.2    Weiner, O.D.3    Srinivasan, S.4    Servant, G.5    Bourne, H.R.6
  • 36
    • 0031906278 scopus 로고    scopus 로고
    • 32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis
    • 32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis. J. Cell Sci. 111(Pt 2), 283-294.
    • (1998) J. Cell Sci. , vol.111 , Issue.PART 2 , pp. 283-294
    • Zhou, K.1    Pandol, S.2    Bokoch, G.3    Traynor-Kaplan, A.E.4
  • 37
    • 0029147402 scopus 로고
    • A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: Biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development
    • Zhou, K., Takegawa, K., Emr, S. D., and Firtel, R. A. (1995). A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol. Cell Biol. 15, 5645-5656.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 5645-5656
    • Zhou, K.1    Takegawa, K.2    Emr, S.D.3    Firtel, R.A.4


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