Activation of Bad trafficking is involved in the BCR-mediated apoptosis of immature B cells

Apoptosis

Volumn 11, Issue 6, 2006, Pages 1003-1012

  Malissein, E ^a   Verdier, M ^a   Ratinaud, M H ^a   Troutaud, D ^a  

^a UNIVERSITÉ DE LIMOGES   (France)

Author keywords

Apoptosis; Bad; BCR; Mitochondria; Phospho Bad; Rafts

Indexed keywords

PROTEIN BAD; PROTEIN BCL 2;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL ISOLATION; CELL SURVIVAL; CONFOCAL MICROSCOPY; EX VIVO STUDY; IMMUNOPRECIPITATION; LIPID RAFT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; B-LYMPHOCYTES; BCL-ASSOCIATED DEATH PROTEIN; CELL LINE, TUMOR; MICE; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, B-CELL;

EID: 33745013176     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-6713-7     Document Type: Article

References (48)

1. Nossal GJV. Negative selection of lymphocytes. Cell 1994; 76: 229-239.
2. Green DR, Scott DW. Activation-induced apoptosis in lymphocytes. Curr Opin Immunol 1994; 6: 476-487.
3. Niiro H, Clark EA. Regulation of B-cell fate by antigen-receptor signals. Nat Rev Immunol 2002; 2: 945-956.
4. Ruvolo PP, Deng X, May WS. Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia 2001; 15: 515-522.
5. Fleischer A, Rebollo A, Ayllon V. BH3-only proteins: The lords of death. Arch. Immunol Ther Exp (Warsz) 2003; 51: 9-17.
6. Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14.3.3 not Bcl-X(L). Cell 1996; 87: 619-628.
7. Bae J, Hsu SY, Leo CP, Zell K, Hsueh AJ. Underphosphorylated BAD interacts with diverse antiapoptotic Bcl-2 family proteins to regulate apoptosis. Apoptosis 2001; 6: 319-330.
8. Datta SR, Ranger AM Lin, et al. Survival factor-mediated Bad phosphorylation raises the mitochondrial threshold for apoptosis. Dev Cell 2002; 3: 631-643.
9. Puthalakath H, Strasser A. Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505-512.
10. Schinzel A, Kaufmann T, Borner C. Bcl-2 family members: Integrators of survival and death signals in physiology and pathology [corrected]. Biochim Biophys Acta 2004; 1644: 95-105. Erratum in: Biochim Biophys Acta 1692: 45.
11. Hinton HJ, Welham MJ. Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells. J Immunol 1999; 162: 7002-7009.
12. Chiang CW, Harris G, Ellig, et al. Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation. Blood 2001; 97: 1289-1297.
13. Zhao S, Konopleva M, Cabreira-Hansen, et al. Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias. Leukemia 2004; 18: 267-275.
14. Cheng PC, Brown BK, Song W, Pierce SK. Translocation of the BCR into lipid rafts reveals a novel step in signaling. J Immunol 2001; 166: 3693-3701.
15. Pierce SK. Lipid rafts and B-cell activation. Nat Rev Immunol 2001; 2: 96-105.
16. Sproul TW, Malapati S, Kim J, Pierce SK. Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells. J Immunol 2000; 165: 6020-6023.
17. Fleischer A, Ghadiri A, Dessauge, et al. Bad-dependent rafts alteration is a consequence of an early intracellular signal triggered by interleukin-4 deprivation. Mol Cancer Res 2004; 2: 674-684.
18. Ayllon V, Fleischer A, Cayla X, Garcia A, Rebollo A. Segregation of Bad from lipid rafts is implicated in the induction of apoptosis. J Immunol 2002; 168: 3387-3393.
19. Benhamou LE, Cazenave P, Sarthou P. Anti-immunoglobulins induce death by apoptosis in WEHI-231 B lymphoma cells. Eur J Immunol 1990; 20: 1405-1407.
20. Hasbold J, Klaus GG. Anti-immunoglobulin antibodies induce apoptosis in immature B cell lymphomas. Eur J Immunol 1990; 20: 1685-1690.
21. Scott DW. Analysis of B cell tolerance in vitro. Adv Immunol 1993; 54: 393-425.
22. Gottschalk AR, Quintans J. Apoptosis in B lymphocytes: The WEHI-231 perspective. Immunol.Cell Biol 1995; 73: 8-16.
23. Malissein E, Verdier M, Ratinaud MH, Troutaud D. Changes in Bad phosphorylation are correlated with BCR-induced apoptosis in WEHI-231 immature B cells. Biochimie 2003; 85: 733-740.
24. Rottenberg H, Wu S. Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells. Biochim Biophys Acta 1998; 1404: 393-404.
25. Harder T, Scheiffele P, Verkade P, Simons K. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 1998; 141: 929-942.
26. Ayllon V, Cayla X, Garcia, et al. Bcl-2 targets protein phosphatase 1 alpha to Bad. J Immunol 2001; 166: 7345-7352.
27. Ezhevsky SA, Toyoshima H, Hunter T, Scott DW. Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas. Mol Biol Cell 1996; 17: 553-564.
28. Klaus GG, Choi MS, Lam EW, Johnson-Leger C, Cliff J. CD40: A pivotal receptor in the determination of life/death decisions in B lymphocytes. Int Rev Immunol 1997; 15: 5-31.
29. Donjerkovic D, Zhang L, Scott DW. Regulation of p27Kip1 accumulation in murine B-lymphoma cells: Role of c-Myc and calcium. Cell Growth Differ 1999; 10: 695-704.
30. (kip1) and cyclin D2 via the PI3K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells. Oncogene 2001; 20: 7352-7367.
31. Enders A, Bouillet P, Puthalakath H, Xu Y, Tarlinton DM, Strasser A. Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreative B cells. J Exp Med 2003; 198: 1119-1126.
32. Strasser A. The role of BH3-only proteins in the immune system. Nat Rev Immunol 2005; 5: 189-200.
33. Ranger AM, Zha J, Harada, et al. Bad-deficient mice develop diffuse large B cell lymphoma. Proc Natl Acad Sci USA 2003; 100: 9324-9329.
34. Datta SR, Katsov A, Hu, et al. 14.3.3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol Cell 2000; 6: 41-51.
35. Muscarella DE, Bloom SE. Cross-linking of surface IgM in the Burkitt's lymphoma cell line ST486 cells provides protection against arsenite- and stress- apoptosis that is mediated by ERK and phosphoinositide 3-kinase signaling pathways. J Biol Chem 2003; 278: 4358-4367.
36. Malissein E, Verdier M, Ratinaud MH, Troutaud D. Bcl-2 protein phosphorylation /dephosphorylation and apoptosis induced by B cell antigen receptor ligation (review). In: Pandalai SG, ed. Trivandrum: Research signpost. Recent research developments in Immunology. 2003: 669-683.
37. Foster LJ, De Hoog CL, Mann M. Unbiased quantitative proteomics of lipid rafts reveal high specificity for signaling factors. Proc Natl Acad Sci USA 2003; Trivandrum: Research signpost 100 : 2813-2818.
38. Garcia A, Cayla X, Fleischer A, et al. Rafts: A simple way to control apoptosis by subcellular redistribution. Biochimie 2003; 85: 727-731.
39. Muppidi JR, Tschopp J, Siegel RM. Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 2004; 21: 461-465.
40. Fais S, De Milito A, Lozupone F. The role of FAS to ezrin association in FAS-mediated apoptosis. Apoptosis 2005; 10: 941-947.
41. Ayllon V, Martinez-A C, Garcia A, Cayla X, Rebollo A. Protein phosphatase 1 alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis. EMBO J 2000; 19: 2237-2246.
42. Bouillet P, Strasser A. BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J Cell Sci 2002; 115: 1567-1574.
43. Hubbard MJ, Cohen P. On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem Sci 1993; 18: 172-177.
44. Faux MC, Scott JD. More on target with protein phosphorylation: Conferring specificity by location. Trends Biochem Sci 1996; 21: 312-315.
45. Garcia A, Cayla X, Guergnon, et al. Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis. Biochimie 2003; 85: 721-726.
46. Garcia A, Cayla X, Caudron, et al. New insights in protein phosphorylation: A signature for protein phosphatase 1 interacting proteins. C R Biol 2004; 327: 93-97.
47. L and Bcl-2. EMBO J 1997; 16: 968-977.
48. L and Bcl-w target protein phosphatase 1α to Bad. Eur J Immunol 2002; 32: 1847-1855.