Synthesis and configurational assignment of the amino alcohol in the eastern fragment of the GE2270 antibiotics by regio- and stereoselective addition of 2-metalated 4-bromothiazoles to α-chiral electrophiles

Journal of Organic Chemistry

Volumn 71, Issue 12, 2006, Pages 4599-4608

  Delgado, Oscar ^a   Heckmann, Golo ^a   Müller, H Martin ^a   Bach, Thorsten ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4-BROMOTHIAZOLES; CHIRAL ELECTROPHILES; REGIOSELECTIVE FUNCTIONALIZATION;

ALDEHYDES; AMINO ACIDS; BROMINE COMPOUNDS; STEREOCHEMISTRY;

ALCOHOLS;

2,4 BROMOTHIAZOLE; AMINOALCOHOL; ANTIBIOTIC AGENT; GE 2270A; MANDELIC ACID DERIVATIVE; PALLADIUM; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DIASTEREOISOMER; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; STEREOCHEMISTRY;

AMINO ALCOHOLS; ANTI-BACTERIAL AGENTS; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; STEREOISOMERISM; THIAZOLES;

EID: 33744923412     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060462g     Document Type: Article

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