Synthesis of the heterocyclic core of the GE2270 antibiotics and structure elucidation of a major degradation product

Angewandte Chemie - International Edition

Volumn 44, Issue 8, 2005, Pages 1199-1201

  Heckmann, Golo ^a   Bach, Thorsten ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Asymmetric synthesis; Cross coupling; Heterocycles; Metalation; Natural products

Indexed keywords

DEGRADATION; ISOMERS; NITROGEN COMPOUNDS; REACTION KINETICS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

DEGRADATION PRODUCTS; DIASTEREOISOMERS; PEPTIDES; PYRIDINES;

ANTIBIOTICS;

GE 2270A; HETEROCYCLIC COMPOUND;

ARTICLE; DIASTEREOISOMER; DRUG DEGRADATION; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS; SYNTHESIS;

ANTI-BACTERIAL AGENTS; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; THIAZOLES;

EID: 15444375711     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200461715     Document Type: Article

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42. +] calcd: 822.1297, found: 822.1289.