Total synthesis of thiostrepton, part 2: Construction of the quinaldic acid macrocycle and final stages of the synthesis

Angewandte Chemie - International Edition

Volumn 43, Issue 38, 2004, Pages 5092-5097

  Nicolaou, K C ^a   Zak, Mark ^a   Safina, Brian S ^a   Lee, Sang Hyup ^a   Estrada, Anthony A ^a  

^a NONE

Author keywords

Antibiotics; Natural products; Peptide coupling; Protecting groups; Total synthesis

Indexed keywords

ACIDS; SYNTHESIS (CHEMICAL);

SENSITIVE FUNCTIONALITIES; THIOSTREPTON;

ANTIBIOTICS;

MACROCYCLIC COMPOUND; QUINALDIC ACID; THIOSTREPTON;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; EPOXIDATION; HYDROLYSIS; REACTION ANALYSIS; STEREOCHEMISTRY;

MACROCYCLIC COMPOUNDS; MOLECULAR CONFORMATION; QUINOLINES; THIOSTREPTON;

EID: 4944267509     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200461341     Document Type: Article

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