Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 22, 2006, Pages 8390-8395

  Romero, Pedro R ^a,b   Zaidi, Saima ^a   Fang, Ya Yin ^b   Uversky, Vladimir N ^b   Radivojac, Predrag ^c   Oldfield, Christopher J ^b   Cortese, Marc S ^b   Sickmeier, Megan ^b   LeGall, Tanguy ^b   Obradovic, Zoran ^d   Dunker, A Keith ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY   (United States)

^d TEMPLE UNIVERSITY   (United States)

Author keywords

Evolution; Intrinsically unstructured; Natively unfolded; Protein structure

Indexed keywords

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; EUKARYOTE EVOLUTION; EXON; GENE REARRANGEMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA SPLICING; STRUCTURE ACTIVITY RELATION; TISSUE SPECIFICITY;

ALTERNATIVE SPLICING; ANIMALS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEINS; TRANSCRIPTION, GENETIC;

EUKARYOTA;

EID: 33744814686     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507916103     Document Type: Article

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