Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

Development

Volumn 133, Issue 9, 2006, Pages 1625-1634

  Watanabe, Yusuke ^a,e   Kokubo, Hiroki ^a,b   Miyagawa Tomita, Sachiko ^c   Endo, Maho ^a   Igarashi, Katsuhide ^d   Aisaki, Ken Ichi ^d   Kanno, Jun ^d   Saga, Yumiko ^a,b  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^e INSTITUT PASTEUR   (France)

Author keywords

AV cushion; EMT; Heart formation; Notch signaling

Indexed keywords

BONE MORPHOGENETIC PROTEIN 6; CELL PROTEIN; CRE RECOMBINASE; JAGGED1; NOTCH1 RECEPTOR; PROTEIN HESR1; PROTEIN TNNI2; UNCLASSIFIED DRUG; WNT2 PROTEIN;

ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR CANAL; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL MATURATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; ENDOCARDIUM; GENE TARGETING; GENETIC ANALYSIS; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; HEART VENTRICLE SEPTUM DEFECT; MESODERM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CYCLE PROTEINS; EMBRYONIC INDUCTION; ENDOCARDIAL CUSHION DEFECTS; HEART; HEART ATRIA; HEART DEFECTS, CONGENITAL; HEART SEPTUM; HEART VENTRICLES; INTEGRASES; MESODERM; MICE; MICE, TRANSGENIC; MORPHOGENESIS; MYOCARDIUM; MYOCYTES, CARDIAC; RECEPTOR, NOTCH1; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; VIRAL PROTEINS;

ANIMALIA;

EID: 33744506422     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02344     Document Type: Article

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