Synthesis of a biotin derivative of iberiotoxin: Binding interactions with streptavidin and the BK Ca2+-activated K+ channel expressed in a human cell line

Bioconjugate Chemistry

Volumn 17, Issue 3, 2006, Pages 689-699

  Bingham, Jon Paul ^a   Bian, Shumin ^b   Tan, Zhi Yong ^c   Takacs, Zoltan ^d   Moczydlowski, Edward ^a  

^a CLARKSON UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CALCIUM COMPOUNDS; CELL CULTURE; CLONING; COENZYMES; DISSOCIATION; FLUORESCENCE; FLUORESCENCE MICROSCOPY; PEPTIDES; SIZE EXCLUSION CHROMATOGRAPHY; SYNTHESIS (CHEMICAL);

BINDING INTERACTION; BK-CHANNEL; CA 2+; HIGH AFFINITY; HUMAN CELL LINES; K+ CHANNELS; SCORPION VENOM; STREPTAVIDIN; SURFACE DISTRIBUTIONS; VENOM PEPTIDES;

AMINO ACIDS;

ANTIBODY; ASPARTIC ACID; BIOTIN DERIVATIVE; CALCIUM ACTIVATED POTASSIUM CHANNEL; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LYSINE DERIVATIVE; N EPSILON (BIOTIN 6 AMIDOCAPROATE)LYSINE; SCORPION VENOM; STREPTAVIDIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL LABELING; CELL LINE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; EMBRYO; FLUORESCENCE MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; NEUROBIOLOGY; NONHUMAN; PATCH CLAMP; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; SKELETAL MUSCLE; SOLID PHASE SYNTHESIS; STEREOSPECIFICITY; STOICHIOMETRY;

SCORPIONES;

EID: 33646918853     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc060002u     Document Type: Article

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