[125I]iberiotoxin-D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels

Biochemistry

Volumn 36, Issue 7, 1997, Pages 1943-1952

  Koschak, Alexandra ^a   Koch, Robert O ^a   Liu, Jessica ^b   Kaczorowski, Gregory J ^b   Reinhart, Peter H ^c   Garcia, Maria L ^b   Knaus, Hans Günther ^a  

^a A 6020   (Austria)

^b MERCK RESEARCH LABORATORIES   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IBERIOTOXIN; MARGATOXIN; ASPARTIC ACID; CALCIUM; PEPTIDE; PHENYLALANINE; POTASSIUM CHANNEL; RADIOACTIVE IODINE; RECOMBINANT PROTEIN; TYROSINE;

ARTICLE; CALCIUM CONDUCTANCE; COMPETITIVE INHIBITION; COVALENT BOND; CROSS LINKING; ESCHERICHIA COLI; LIGAND BINDING; LIPID BILAYER; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; SARCOLEMMA; SMOOTH MUSCLE FIBER; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CATTLE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; FEMALE; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN BINDING; RADIOASSAY; SMOOTH MUSCLE; TRACHEA; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; CALCIUM; CATTLE; FEMALE; IODINE RADIOISOTOPES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; OXIDATION-REDUCTION; PEPTIDES; PHENYLALANINE; POTASSIUM CHANNELS; PROTEIN BINDING; RADIOLIGAND ASSAY; RECOMBINANT PROTEINS; SARCOLEMMA; TRACHEA; TYROSINE; XENOPUS LAEVIS;

EID: 0030614898     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962074m     Document Type: Article

References (54)

1. Anderson, C. S., MacKinnon, R., Smith, C., & Miller, C. (1988) J. Gen. Physiol. 91, 317-333.
2. Arkett, S. A., Dixon, J., Yang, J. N., Sakai, D. D., Minkin, C., & Sims, S. M. (1994) Receptors Channels. 2, 281-293.
3. Bontems, F., Roumestand, C., Boyot, P., Gilquin, B., Doljansky, Y., Menez, A., & Toma, F. (1991) Eur. J. Biochem. 196, 19-28.
4. Bontems, F., Gilquin, B., Roumestand, C., Menez, A., & Toma, F. (1992) Biochemistry 31, 7756-7764.
5. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
6. Brugnara, C., De Franceschi, L., & Alper, S. L. (1993a) J. Clin. Invest. 92, 520-526.
7. Brugnara, C., De Franceschi, L., & Alper, S. L. (1993b) J. Biol. Chem. 268, 8760-8768.
8. Butler, A., Tsunoda, S., McCobb, D. P., Wei, A., & Salkoff, L. (1993) Science 261, 221-224.
9. Chandy, K. G., & Gutman, G. A. (1995) in Handbook of receptors and channels: ligand and voltage-gated ion channels (North, R. A., Ed.) pp 1-71, CRC Press, Boca Raton, FL.
10. Chandy, K. G., Gutman, G. A., & Grissmer, S. (1993) Semin. Neurosci. 5, 125-134.
11. DeLean, A., Munson, P. J., & Rodbard, D. (1978) Am. J. Physiol. 4, E97-E102.
12. Deutsch, C., Price, M., Lee, S., King, V. F., & Garcia, M. L. (1991) J. Biol. Chem. 266, 3668-3674.
13. DiChiara, T. J., & Reinhart, P. H. (1995) J. Physiol. 439, 403-418.
14. Dumont, J. N. (1972) J. Morphol. 136, 153-179.
15. Galvez, A., Gimenez-Gallego, G., Reuben, J. P., Roy-Contancin, L., Feigenbaum, P., Kaczorowski, G. J., & Garcia, M. L. (1990) J. Biol. Chem. 265, 11083-11090.
16. Garcia-Calvo, M., Leonard, R. J., Novick, J., Stevens, S. P., Schmalhofer, W. A., Kaczorowski, G. J., & Garcia, M. L. (1993) J. Biol. Chem. 268, 18866-18874.
17. Garcia-Calvo, M., Knaus, H. G., McManus, O. B., Giangiacomo, K. M., Kaczorowski, G.J., & Garcia, M. L. (1994) J. Biol. Chem. 269, 676-682.
18. Giangiacomo, K. M., Garcia, M. L., & McManus, O. B. (1992) Biochemistry 31, 6719-6727.
19. Giangiacomo, K. M., Garcia-Calvo, M., Knaus, H. G., Mullmann, T. J., Garcia, M. L., & McManus, O. B. (1995) Biochemistry 34, 15849-15862.
20. Gimenez-Gallego, G., Navia, M. A., Reuben, J. P., Katz, G. M., Kaczorowski, G. J., & Garcia, M. L. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 3329-3333.
21. Grissmer, S., Nguyen, A. N., Aiyar, J., Hanson, D. C., Mather, R. J., Gutman, G. A., Karmilowicz, M. J., Auperin, D. D., & Chandy, K. G. (1994) Mol. Pharmacol. 45, 1227-1234.
22. Hermann, A., & Erxleben, C. (1987) J. Gen. Physiol. 90, 27-47.
23. Kaczorowski, G. J., Knaus, H. G., Leonard, R. J., McManus, O. B., & Garcia, M. L. (1996) J. Bioenerg. Biomembr. 28, 253-265.
24. Knaus, H. G., Folander, K., Garcia-Calvo, M., Garcia, M. L., Kaczorowski, G. J., Smith, M., & Swanson, R. (1994a) J. Biol. Chem. 269, 17274-17278.
25. Knaus, H. G., Garcia-Calvo, M., Kaczorowski, G. J., & Garcia, M. L. (1994b) J. Biol. Chem. 269, 3921-3924.
26. Knaus, H. G., McManus, O. B., Lee, S. H., Schmalhofer, W. A., Garcia-Calvo, M., Helms, L. M. H., Sanchez, M., Giangiacomo, K. M., Reuben, J. P., Smith, A. B., III, Kaczorowski, G. J., & Garcia, M. L. (1994c) Biochemistry 33, 5819-5828.
27. Knaus, H. G., Koch, R. O. A., Eberhart, A., Kaczorowski, G. J., Garcia, M. L., & Slaughter, R. S. (1995) Biochemistry 34, 13627-13634.
28. Knaus, H. G., Schwarzer, C., Koch, R. O. A., Eberhart, A., Kaczorowski, G. J., Glossmann, H., Wunder, F., Pongs, O., Garcia, M. L., & Sperk, G. (1996) J. Neurosci. 16, 955-963.
29. Latorre, R., Oberhauser, A., Labarca, P., & Alvarez, O. (1989) Annu. Rev. Physiol. 51, 385-399.
30. Leonard, R. J., Garcia, M. L., Slaughter, R. S., & Reuben, J. P. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 10094-10098.
31. Linden, J. (1982) J. Cyclic Nucleotide Res. 8, 163-172.
32. MacKinnon, R., & Miller, C. (1988) J. Gen. Physiol. 91, 335-349.
33. McManus, O. B., Harris, G. H., Giangiacomo, K. M., Feigenbaum, P., Reuben, J. P., Addy, M. E., Burka, J. F., Kaczorowski, G. J., & Garcia, M. L. (1993) Biochemistry 32, 6128-6133.
34. McManus, O. B., Pallanck, L., Helms, L. M. H., Swanson, R., & Leonard, R. J. (1995) Neuron 14, 645-650.
35. Miledi, R. (1982) Proc. R. Soc. London 215, 492-497.
36. Miller, C. (1988) Neuron 1, 1003-1006.
37. Miller, C., Moczydlowski, E., Latorre, R., & Philips, M. (1985) Nature 313, 316-318.
38. Oosawa, Y., Ashcroft, S. J., & Ashcroft, F. M. (1992) Diabetologia 35, 619-623.
39. Park, C.-S., Hausdorff, S. F., & Miller, C. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 2046-2050.
40. Rane, S. G. (1991) Am. J. Physiol. 260, C104-C112.
41. Reinhart, P. H., Chung, S., & Levitan, I. B. (1989) Neuron 2, 1031-1041.
42. Sanger, F., Nicklen, S., & Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
43. Scott, V. E. S., Parcej, D. N., Keen, J. N., Findlay, J. B., & Dolly, J. O. (1990) J. Biol. Chem. 265, 20094-20097.
44. Slaughter, R. S., Shevell, J. L., Felix, J. P., Garcia, M. L., & Kaczorowski, G. J. (1989) Biochemistry 28, 3995-4002.
45. Solaro, C., & Lingle, C. (1992) Science 257, 1694-1698.
46. Stampe, P., Kolmakova Partensky, L., & Miller, C. (1994) Biochemistry 33, 443-450.
47. Tseng-Crank, J., Foster, C. D., Krause, J. D., Mertz, R., Godinot, N., DiChiara, T. J., & Reinhart, P. H. (1994) Neuron 13, 1315-1330.
48. Van Renterghem, C., & Lazdunski, M. (1992) Pflügers Arch. 420, 417-423.
49. Vázquez, J., Feigenbaum, P., Katz, G., King, V. F., Reuben, J. P., Roy-Contancin, L., Slaughter, R. S., Kaczorowski, G. J., & Garcia, M. L. (1989) J. Biol. Chem. 264, 20902-20909.
50. Vázquez, J., Feigenbaum, P., King, V. F., Kaczorowski, G. J., & Garcia, M. L. (1990) J. Biol. Chem. 265, 15564-15571.
51. Wang, H., Kunkel, D. D., Schwartzkroin, P. A., & Tempel, B. L. (1994) J. Neurosci. 14, 4588-4599.
52. Wang, X., Inukai, T., Greer, M. A., & Greer, S. E. (1994) Brain. Res. 662, 83-87.
53. Williams, J. R., Katz, G. M., Roy-Contancin, L., & Reuben, J. P. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 9360-9364.
54. Zweifach, A., Desir, G. V., Aronson, P. S., & Giebisch, G. H. (1991) Am. J. Physiol. 261, F187-F196.