Synthesis, characterization, and application of Cy-dye- and Alexa-dye-labeled hongotoxin1 analogues. The first high affinity fluorescence probes for voltage-gated K+ channels

Bioconjugate Chemistry

Volumn 13, Issue 3, 2002, Pages 416-425

  Pragl, Bernt ^b   Koschak, Alexandra ^b   Trieb, Maria ^b   Obermair, Gerald ^b   Kaufmann, Walter A ^b   Gerster, Uli ^b   Blanc, Eric ^a   Hahn, Christoph ^c   Prinz, Heino ^d   Schütz, Gerhard ^c   Darbon, Herve ^b   Gruber, Hermann J ^c   Knaus, Hans Günther ^b  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b CNRS   (France)

^c JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^d MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; NEURONS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROBES; TOXIC MATERIALS;

3 10 HELIX; AFFINITY INTERACTIONS; FLUORESCENCE DYES; FLUORESCENCE PROBES; HELICAL CONFORMATION; HIGH AFFINITY; K+ CHANNELS; NMR-SPECTROSCOPY; THREE-DIMENSIONAL STRUCTURE; TOXIN CONCENTRATIONS;

AMINO ACIDS;

ALEXA; CENTRUROIDES; CENTRUROIDES LIMBATUS; GARCIA;

ALEXA594; CARBOCYANINE; CYANINE DYE 3; CYANINE DYE 5; FLUORESCENT DYE; HONGOTOXIN 1; LIGAND; NEUROTOXIN; ORGANIC COMPOUND; RECOMBINANT PROTEIN; SCORPION VENOM; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL; ARTICLE; BRAIN; CHANNEL GATING; CHEMISTRY; DRUG EFFECT; GENETICS; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMID; PROTEIN BINDING; PROTEIN CONFORMATION; RADIOASSAY; RAT; SYNAPSE VESICLE; SYNTHESIS;

ANIMALS; BRAIN; CARBOCYANINES; FLUORESCENT DYES; ION CHANNEL GATING; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; NEUROTOXINS; ORGANIC CHEMICALS; PLASMIDS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; RATS; RECOMBINANT PROTEINS; SCORPION VENOMS; SYNAPTIC VESICLES;

EID: 0036000114     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc015543s     Document Type: Article

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