Simultaneous binding of basic peptides at intracellular sites on a large conductance Ca2+-activated K+ channel. Equilibrium and kinetic basis of negatively coupled ligand interactions

Journal of General Physiology

Volumn 113, Issue 2, 1999, Pages 295-320

  Favre, Isabelle ^a   Moczydlowski, Edward ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aprotinin; Bovine pancreatic trypsin inhibitor; Charybdotoxin; Dendrotoxin; Kunitz inhibitor

Indexed keywords

APROTININ; CALCIUM; CHARYBDOTOXIN; DENDROTOXIN; LIGAND; POTASSIUM; POTASSIUM CHANNEL; TRYPSIN INHIBITOR;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CALCIUM CONDUCTANCE; INHIBITION KINETICS; ION CONDUCTANCE; LIGAND BINDING; MATHEMATICAL MODEL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR OCCUPANCY;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; APROTININ; BINDING SITES; ELAPID VENOMS; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; LIGANDS; MOLECULAR SEQUENCE DATA; PATCH-CLAMP TECHNIQUES; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; TRYPSIN INHIBITORS;

EID: 0032921414     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.113.2.295     Document Type: Article

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