Glycine 30 in iberiotoxin is a critical determinant of its specificity for maxi-K versus KV channels

FEBS Letters

Volumn 527, Issue 1-3, 2002, Pages 298-302

  Schroeder, Nathan ^a   Mullmann, Theodore J ^a   Schmalhofer, W A ^b   Gao, Ying Duo ^b   Garcia, Maria L ^b   Giangiacomo, Kathleen M ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

K peptide; Charybdotoxin; Iberiotoxin; KV1.3 channel; Maxi K channel

Indexed keywords

ACID; GLYCINE; IBERIOTOXIN; MUTANT PROTEIN; POTASSIUM; POTASSIUM CHANNEL;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ASPARAGINE; CELLS, CULTURED; GLYCINE; HUMANS; KV1.3 POTASSIUM CHANNEL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; SCORPION VENOMS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TOXINS, BIOLOGICAL;

EID: 0037063370     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)03256-8     Document Type: Article

References (39)

1. Anwer K., Oberti C., Perez G.J., Perez-Reyes N., McDougall J.K., Monga M., Sanborn B.M., Stefani E., Toro L. Am. J. Physiol. 265:1993;C976-985.
2. Brenner R., Perez G.J., Bonev A.D., Eckman D.M., Kosek J.C., Wiler S.W., Patterson A.J., Nelson M.T., Aldrich R.W. Nature. 407:2000;870-876.
3. Nelson M.T., Cheng H., Rubart M., Santana L.F., Bonev A.D., Knot H.J., Lederer W.J. Science. 270:1995;633-637.
4. Ramanathan K., Michael T.H., Jiang G.J., Hiel H., Fuchs P.A. Science. 283:1999;215-217.
5. Shipston M.J., Kelly J.S., Antoni F.A. J. Biol. Chem. 271:1996;9197-9200.
6. Hu H., Shao L.R., Chavoshy S., Gu N., Trieb M., Behrens R., Laake P., Pongs O., Knaus H.G., Ottersen O.P., Storm J.F. J. Neurosci. 21:2001;9585-9597.
7. Galvez A., Gimenez-Gallego G., Reuben J.P., Roy-Contancin L., Feigenbaum P., Kaczorowski G.J., Garcia M.L. J. Biol. Chem. 265:1990;11083-11090.
8. Giangiacomo K.M., Gabriel J., Fremont V., Mullmann T.J. Perspect. Drug Discov. Des. 15/16:1999;167-186.
9. Mullmann T.J., Spence K.T., Schroeder N.E., Fremont V.F., Christian E.P., Giangiacomo K.M. Biochemistry. 40:2001;10987-10997.
10. Giangiacomo K.M., Sugg E.E., Garcia-Calvo M., Leonard R.J., McManus O.B., Kaczorowski G.J., Garcia M.L. Biochemistry. 32:1993;2363-2370.
11. Leonard R.J., Garcia M.L., Slaughter R.S., Reuben J.P. Proc. Natl. Acad. Sci. USA. 89:1992;10094-10098.
12. Mullmann T.J., Munujos P., Garcia M.L., Giangiacomo K.M. Biochemistry. 38:1999;2395-2402.
13. Sanger F., Nicklen S., Coulson A.R. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
14. Hanner M., Vianna-Jorge R., Kamassah A., Schmalhofer W.A., Knaus H.G., Kaczorowski G.J., Garcia M.L. J. Biol. Chem. 273:1998;16289-16296.
15. Helms L.M., Felix J.P., Bugianesi R.M., Garcia M.L., Stevens S., Leonard R.J., Knaus H.G., Koch R., Wanner S.G., Kaczorowski G.J., Slaughter R.S. Biochemistry. 36:1997;3737-3744.
16. Koschak A., Bugianesi R.M., Mitterdorfer J., Kaczorowski G.J., Garcia M.L., Knaus H.G. J. Biol. Chem. 273:1998;2639-2644.
17. Knaus H.G., Koch R.O., Eberhart A., Kaczorowski G.J., Garcia M.L., Slaughter R.S. Biochemistry. 34:1995;13627-13634.
18. Koschak A., Koch R.O., Liu J., Kaczorowski G.J., Reinhart P.H., Garcia M.L., Knaus H.G. Biochemistry. 36:1997;1943-1952.
19. Linden J. J. Cycl. Nucleotide Res. 8:1982;163-172.
20. Bontems F., Gilquin B., Roumestand C., Menez A., Toma F. Biochemistry. 31:1992;7756-7764.
21. Johnson B.A., Sugg E.E. Biochemistry. 31:1992;8151-8159.
22. Goldstein S.A., Pheasant D.J., Miller C. Neuron. 12:1994;1377-1388.
23. Stampe P., Kolmakova-Partensky L., Miller C. Biochemistry. 33:1994;443-450.
24. Giangiacomo K.M., Garcia M.L., McManus O.B. Biochemistry. 31:1992;6719-6727.
25. Ferrat G., Bernard C., Fremont V., Mullmann T.J., Giangiacomo K.M., Darbon H. Biochemistry. 40:2001;10998.
26. Ranganathan R., Lewis J.H., MacKinnon R. Neuron. 16:1996;131-139.
27. Garcia M.L., Gao Y., McManus O.B., Kaczorowski G.J. Toxicon. 39:2001;739-748.
28. Gimenez-Gallego G., Navia M.A., Reuben J.P., Katz G.M., Kaczorowski G.J., Garcia M.L. Proc. Natl. Acad. Sci. USA. 85:1988;3329-3333.
29. Novick J., Leonard R.J., King V.F., Schmalhofer W., Kaczorowski G.J., Garcia M.L. Biophys. J. 59:1991;78a.
30. Lucchesi K., Ravindran A., Young H., Moczydlowski E. J. Membr. Biol. 109:1989;269-281.
31. Romi-Lebrun R., Lebrun B., Martin-Eauclaire M.F., Ishiguro M., Escoubas P., Wu F.Q., Hisada M., Pongs O., Nakajima T. Biochemistry. 36:1997;13473-13482.
32. Possani L.D., Martin B.M., Svendsen I.B. Carlsberg Res. Commun. 47:1982;285-289.
33. Garcia-Calvo M., Leonard R.J., Novick J., Stevens S.P., Schmalhofer W., Kaczorowski G.J., Garcia M.L. J. Biol. Chem. 268:1993;18866-18874.
34. Martin B.M., Ramirez A.N., Gurrola G.B., Nobile M., Prestipino G., Possani L.D. Biochem. J. 304:1994;51-56.
35. Rogowski R.S., Krueger B.K., Collins J.H., Blaustein M.P. Proc. Natl. Acad. Sci. USA. 91:1994;1475-1479.
36. Crest M., Jacquet G., Gola M., Zerrouk H., Benslimane A., Rochat H., Mansuelle P., Martin-Eauclaire M.F. J. Biol. Chem. 267:1992;1640-1647.
37. Garcia M.L., Garcia-Calvo M., Hidalgo P., Lee A., MacKinnon R. Biochemistry. 33:1994;6834-6839.
38. Laraba-Djebari F., Legros C., Crest M., Ceard B., Romi R., Mansuelle P., Jacquet G., van Rietschoten J., Gola M., Rochat H., et al. J. Biol. Chem. 269:1994;32835-32843.
39. Jaravine V.A., Nolde D.E., Reibarkh M.J., Korolkova Y.V., Kozlov S.A., Pluzhnikov K.A., Grishin E.V., Arseniev A.S. Biochemistry. 36:1997;1223-1232.