Activation and roles of ALK4/ALK7-mediated maternal TGFβ signals in zebrafish embryo

Biochemical and Biophysical Research Communications

Volumn 345, Issue 2, 2006, Pages 694-703

  Sun, Zhihui ^a   Jin, Peng ^a   Tian, Tian ^a   Gu, Yi ^a   Chen, Ye Guang ^a   Meng, Anming ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Activin; Maternal; Mesoderm induction; Nodal; Smad2; Smad3; TGF ; Vg1; Zebrafish

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN; ACTIVIN RECEPTOR LIKE KINASE 4; ACTIVIN RECEPTOR LIKE KINASE 7; CELL MARKER; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN NODAL; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLASTULA; CELL CYCLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; MESODERM; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMITE; ZEBRA FISH;

ACTIVIN RECEPTORS; ANIMALS; BENZAMIDES; BLASTULA; CELL CYCLE; DIOXOLES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MESODERM; MUTATION; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VERTEBRATES; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; VERTEBRATA;

EID: 33646836098     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.04.148     Document Type: Article

References (40)

1. Ubbels G.A., and Nieuwkoop P.D. The formation of mesoderm in urodelean amphibians. IV. Quantitative evidence for the purely ectodermal origin of the entire mesoderm and of the pharyngeal endoderm. Roux's Arch. 169 (1972) 185-199
2. Woodland H.R., and Jones E.A. The development of animal cap cells in Xenopus: a measure of the start of animal cap competence to form mesoderm. Development 101 (1987) 557-564
3. Smith J.C. Mesoderm-inducing factors and mesodermal patterning. Curr. Opin. Cell Biol. 7 (1995) 856-861
4. Agius E., Oelgeschlager M., Wessely O., Kemp C., and De Robertis E.M. Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development 127 (2000) 1173-1183
5. Tian T., and Meng A.M. Nodal signals pattern vertebrate embryos. Cell. Mol. Life Sci. 63 (2006) 672-685
6. Chen Y.G., and Meng A.M. Negative regulation of TGF-beta signaling in development. Cell Res. 14 (2004) 441-449
7. Shi Y., and Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113 (2003) 685-700
8. Hemmati-Brivanlou A., and Melton D.A. A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359 (1992) 609-614
9. Wittbrodt J., and Rosa F.M. Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin. Genes Dev. 8 (1994) 1448-1462
10. Chang C., Wilson P.A., Mathews L.S., and Hemmati-Brivanlou A. A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development 124 (1997) 827-837
11. Gore A.V., Maegawa S., Cheong A., Gilligan P.C., Weinberg E.S., and Sampath K. The zebrafish dorsal axis is apparent at the four-cell stage. Nature 438 (2005) 1030-1035
12. Laping N.J., Grygielko E., Mathur A., Butter S., Bomberger J., Tweed C., Martin W., Fornwald J., Lehr R., Harling J., Gaster L., Callahan J.F., and Olson B.A. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol. Pharmacol. 62 (2002) 58-64
13. Callahan J.F., Burgess J.L., Fornwald J.A., Gaster L.M., Harling J.D., Harrington F.P., Heer J., Kwon C., Lehr R., Mathur A., Olson B.A., Weinstock J., and Laping N.J. Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5). J. Med. Chem. 45 (2002) 999-1001
14. Inman G.J., Nicolas F.J., Callahan J.F., Harling J.D., Gaster L.M., Reith A.D., Laping N.J., and Hill C.S. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 62 (2002) 65-74
15. Carcamo J., Weis F.M., Ventura F., Wieser R., Wrana J.L., Attisano L., and Massague J. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Mol. Cell. Biol. 14 (1994) 3810-3821
16. Reissmann E., Jornvall H., Blokzijl A., Andersson O., Chang C., Minchiotti G., Persico M.G., Ibanez C.F., and Brivanlou A.H. The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes Dev. 15 (2001) 2010-2022
17. Cheng S.K., Olale F., Bennett J.T., Brivanlou A.H., and Schier A.F. EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes Dev. 17 (2003) 31-36
18. Gritsman K., Zhang J., Cheng S., Heckscher E., Talbot W.S., and Schier A.F. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell 97 (1999) 121-132
19. Kimmel C.B., Ballard W.W., Kimmel S.R., Ullmann B., and Schilling T.F. Stages of embryonic development of the zebrafish. Dev. Dyn. 203 (1995) 253-310
20. Dennler S., Itoh S., Vivien D., ten Dijke P., Huet S., and Gauthier J.M. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17 (1998) 3091-3100
21. Huang H.C., Murtaugh L.C., Vize P.D., and Whitman M. Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo. EMBO J. 14 (1995) 5965-5973
22. Korchynskyi O., and ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J. Biol. Chem. 277 (2002) 4883-4891
23. Joore J., Fasciana C., Speksnijder J.E., Kruijer W., Destree O.H., van den Eijnden-van Raaij A.J., de Laat S.W., and Zivkovic D. Regulation of the zebrafish goosecoid promoter by mesoderm inducing factors and Xwnt1. Mech. Dev. 55 (1996) 3-18
24. Rebagliati M.R., Toyama R., Fricke C., Haffter P., and Dawid I.B. Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev. Biol. 199 (1998) 261-272
25. Thisse C., and Thisse B. Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development 126 (1999) 229-240
26. Dick A., Mayr T., Bauer H., Meier A., and Hammerschmidt M. Cloning and characterization of zebrafish smad2, smad3 and smad4. Gene 246 (2000) 69-80
27. Pogoda H.M., and Meyer D. Zebrafish Smad7 is regulated by Smad3 and BMP signals. Dev. Dyn. 224 (2002) 334-349
28. Baker J.C., and Harland R.M. A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 10 (1996) 1880-1889
29. Schier A.F., Neuhauss S.C., Helde K.A., Talbot W.S., and Driever W. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development 124 (1997) 327-342
30. Rebagliati M.R., Toyama R., Haffter P., and Dawid I.B. cyclops encodes a nodal-related factor involved in midline signaling. Proc. Natl. Acad. Sci. USA 95 (1998) 9932-9937
31. Zhang L., Zhou H., Su Y., Sun Z., Zhang H., Zhang Y., Ning Y., Chen Y.G., and Meng A. Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors. Science 306 (2004) 114-117
32. Feldman B., Gates M.A., Egan E.S., Dougan S.T., Rennebeck G., Sirotkin H.I., Schier A.F., and Talbot W.S. Zebrafish organizer development and germ-layer formation require nodal-related signals. Nature 395 (1998) 181-185
33. Thisse B., Wright C.V., and Thisse C. Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature 403 (2000) 425-428
34. Kane D.A., and Kimmel C.B. The zebrafish midblastula transition. Development 119 (1993) 447-456
35. Stachel S.E., Grunwald D.J., and Myers P.Z. Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish. Development 117 (1993) 1261-1274
36. Krauss S., Concordet J.P., and Ingham P.W. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75 (1993) 1431-1444
37. Besser D. Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. J. Biol. Chem. 279 (2004) 45076-45084
38. Hjelmeland M.D., Hjelmeland A.B., Sathornsumetee S., Reese E.D., Herbstreith M.H., Laping N.J., Friedman H.S., Bigner D.D., Wang X.F., and Rich J.N. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Mol. Cancer Ther. 3 (2004) 737-745
39. Nicolas F.J., De Bosscher K., Schmierer B., and Hill C.S. Analysis of Smad nucleocytoplasmic shuttling in living cells. J. Cell Sci. 117 (2004) 4113-4125
40. James D., Levine A.J., Besser D., and Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132 (2005) 1273-1282