-
1
-
-
0034706917
-
Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants
-
Asaad NA, Zeng Z-C, Guan J, Thacker J, Iliakis G. 2000. Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants. Oncogene 29:5788-5800.
-
(2000)
Oncogene
, vol.29
, pp. 5788-5800
-
-
Asaad, N.A.1
Zeng, Z.-C.2
Guan, J.3
Thacker, J.4
Iliakis, G.5
-
2
-
-
0028213350
-
Radiosensitivity in ataxia-telangiectasia: Anomalies in radiation-induced cell cycle delay
-
Beamish H, Lavin MF. 1994. Radiosensitivity in ataxia-telangiectasia: Anomalies in radiation-induced cell cycle delay. International Journal of Radiation Biology 65:175-184.
-
(1994)
International Journal of Radiation Biology
, vol.65
, pp. 175-184
-
-
Beamish, H.1
Lavin, M.F.2
-
3
-
-
0029829249
-
Defect in multiple cell cycle checkpoints in ataxia-telangiectasia post-irradiation
-
Beamish H, Williams R, Chen P, Lavin MF. 1996. Defect in multiple cell cycle checkpoints in ataxia-telangiectasia post-irradiation. Journal of Biological Chemistry 271:20486-20493.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 20486-20493
-
-
Beamish, H.1
Williams, R.2
Chen, P.3
Lavin, M.F.4
-
4
-
-
0030921428
-
The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells
-
Blasina A, Paegle ES, McGowan CH. 1997. The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells. Molecular Biology of the Cell 8:1013-1023.
-
(1997)
Molecular Biology of the Cell
, vol.8
, pp. 1013-1023
-
-
Blasina, A.1
Paegle, E.S.2
McGowan, C.H.3
-
5
-
-
0017747587
-
The action of caffeine on X-irradiated HeLa cells. II. Synergistic lethality
-
Busse PM, Bose SK, Jones RW, Tolmach LJ. 1977. The action of caffeine on X-irradiated HeLa cells. II. Synergistic lethality. Radiation Research 71:666-677.
-
(1977)
Radiation Research
, vol.71
, pp. 666-677
-
-
Busse, P.M.1
Bose, S.K.2
Jones, R.W.3
Tolmach, L.J.4
-
6
-
-
0018092001
-
The action of caffeine on X-irradiated HeLa cells. III. Enhancement of X-ray-induced killing during G2 arrest
-
Busse PM, Bose SK, Jones RW, Tolmach LJ. 1978. The action of caffeine on X-irradiated HeLa cells. III. Enhancement of X-ray-induced killing during G2 arrest Radiation Research 76:292-307.
-
(1978)
Radiation Research
, vol.76
, pp. 292-307
-
-
Busse, P.M.1
Bose, S.K.2
Jones, R.W.3
Tolmach, L.J.4
-
7
-
-
7444232599
-
Effect of pH on radiation-induced p53 expression
-
Choi EK, Roberts KJ, Griffin RJ, Han TH, Lim BU, Song CW, Park HJ. 2004. Effect of pH on radiation-induced p53 expression. International Journal of Radiation Oncology Biology Physics 60:1264-1271.
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.60
, pp. 1264-1271
-
-
Choi, E.K.1
Roberts, K.J.2
Griffin, R.J.3
Han, T.H.4
Lim, B.U.5
Song, C.W.6
Park, H.J.7
-
8
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari B, Rhind N, Russell P. 1997. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 277:1495-1497.
-
(1997)
Science
, vol.277
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
9
-
-
2642543876
-
Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells
-
(Amst)
-
Goodarzi AA, Lees-Miller SP. 2004. Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells. DNA Repair (Amst) 3(7):753-767.
-
(2004)
DNA Repair
, vol.3
, Issue.7
, pp. 753-767
-
-
Goodarzi, A.A.1
Lees-Miller, S.P.2
-
10
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
Hunter T. 1995. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling. Cell 80:225-236.
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
11
-
-
0020629716
-
Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: The importance of progression through the cell cycle for caffeine enhancement of killing
-
Iliakis G, Nusse M. 1983. Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: The importance of progression through the cell cycle for caffeine enhancement of killing. International Journal of Radiation Biology Related Studies in Physics, Chemistry, and Medicine 43:649-663.
-
(1983)
International Journal of Radiation Biology Related Studies in Physics, Chemistry, and Medicine
, vol.43
, pp. 649-663
-
-
Iliakis, G.1
Nusse, M.2
-
12
-
-
0141757479
-
DNA damage checkpoint control in cells exposed to ionizing radiation
-
Iliakis G, Wang Y, Guan J, Wang H. 2003. DNA damage checkpoint control in cells exposed to ionizing radiation. Oncogene 22:5834-5847.
-
(2003)
Oncogene
, vol.22
, pp. 5834-5847
-
-
Iliakis, G.1
Wang, Y.2
Guan, J.3
Wang, H.4
-
13
-
-
0036147184
-
Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells
-
Jha MN, Bamburg JR, Bernstein BW, Bedford JS. 2002. Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells. Radiation Research 157:26-31.
-
(2002)
Radiation Research
, vol.157
, pp. 26-31
-
-
Jha, M.N.1
Bamburg, J.R.2
Bernstein, B.W.3
Bedford, J.S.4
-
15
-
-
0033552943
-
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
-
Lopez-Girona A, Furnari B, Mondesert O, Russell P. 1999. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature 397:172-175.
-
(1999)
Nature
, vol.397
, pp. 172-175
-
-
Lopez-Girona, A.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
16
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, Elledge SJ. 1998. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282:1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
17
-
-
0030969423
-
Fragments of ATM which have dominant-negative or complementing activity
-
Morgan SE, Lovly C, Pandita TK, Shiloh Y, Kastan MB. 1997. Fragments of ATM which have dominant-negative or complementing activity. Molecular and Cellular Biology 17:2020-2029.
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 2020-2029
-
-
Morgan, S.E.1
Lovly, C.2
Pandita, T.K.3
Shiloh, Y.4
Kastan, M.B.5
-
18
-
-
0028925622
-
Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells
-
Palayoor ST, Macklis RM, Bump EA, Coleman CN. 1995. Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells. Radiation Research 141:235-243.
-
(1995)
Radiation Research
, vol.141
, pp. 235-243
-
-
Palayoor, S.T.1
Macklis, R.M.2
Bump, E.A.3
Coleman, C.N.4
-
20
-
-
0037230108
-
Influence of environmental pH on G2-phase arrest caused by ionizing radiation
-
Park HJ, Lee SH, Chung H, Rhee YH, Lim BU, Ha SW, Griffin RJ, Lee HS, Song CW, Choi EK. 2003. Influence of environmental pH on G2-phase arrest caused by ionizing radiation. Radiation Research 159:86-93.
-
(2003)
Radiation Research
, vol.159
, pp. 86-93
-
-
Park, H.J.1
Lee, S.H.2
Chung, H.3
Rhee, Y.H.4
Lim, B.U.5
Ha, S.W.6
Griffin, R.J.7
Lee, H.S.8
Song, C.W.9
Choi, E.K.10
-
21
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277:1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
22
-
-
0028936626
-
Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay
-
Powell SN, DeFrank JS, Connell P, Eogan M, Preffer F, Dombkowski D, Tang W, Friend S. 1995. Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay. Cancer Research 55:1643-1648.
-
(1995)
Cancer Research
, vol.55
, pp. 1643-1648
-
-
Powell, S.N.1
DeFrank, J.S.2
Connell, P.3
Eogan, M.4
Preffer, F.5
Dombkowski, D.6
Tang, W.7
Friend, S.8
-
23
-
-
0036157566
-
Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner
-
Qi W, Qiao D, Martinez JD. 2002. Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner. Radiation Research 157:166-174.
-
(2002)
Radiation Research
, vol.157
, pp. 166-174
-
-
Qi, W.1
Qiao, D.2
Martinez, J.D.3
-
24
-
-
0028985932
-
Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells
-
Russell KJ, Wiens LW, Demers GW, Galloway DA, Plon SE, Groudine M. 1995. Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells. Cancer Research 55:1639-1642.
-
(1995)
Cancer Research
, vol.55
, pp. 1639-1642
-
-
Russell, K.J.1
Wiens, L.W.2
Demers, G.W.3
Galloway, D.A.4
Plon, S.E.5
Groudine, M.6
-
25
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ. 1997. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 277:1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
26
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, Karnitz LM, Abraham RT. 1999. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Research 59:4375-4382.
-
(1999)
Cancer Research
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
27
-
-
0033406451
-
Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation
-
Suganuma M, Kawabe T, Hori H, Funabiki T, Okamoto T. 1999. Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation. Cancer Research 59:5887-5891.
-
(1999)
Cancer Research
, vol.59
, pp. 5887-5891
-
-
Suganuma, M.1
Kawabe, T.2
Hori, H.3
Funabiki, T.4
Okamoto, T.5
-
28
-
-
0027296216
-
Differential post-irradiation caffeine response in normal diploid versus SV40-transformed human fibroblasts: Potential role of nuclear organization and protein-composition
-
Taylor YC, Parsian AJ, Duncan PG. 1993. Differential post-irradiation caffeine response in normal diploid versus SV40-transformed human fibroblasts: potential role of nuclear organization and protein-composition. International Journal of Radiation Biology 64:57-70.
-
(1993)
International Journal of Radiation Biology
, vol.64
, pp. 57-70
-
-
Taylor, Y.C.1
Parsian, A.J.2
Duncan, P.G.3
-
29
-
-
0025838748
-
Efficacy of pentoxifylline as a modulator of alkylating agent activity in vitro and in vivo
-
Teicher BA, Holden SA, Herman TS, Epelbaum R, Pardee AB, Dezube B. 1991. Efficacy of pentoxifylline as a modulator of alkylating agent activity in vitro and in vivo. Anticancer Research 11:1555-1560.
-
(1991)
Anticancer Research
, vol.11
, pp. 1555-1560
-
-
Teicher, B.A.1
Holden, S.A.2
Herman, T.S.3
Epelbaum, R.4
Pardee, A.B.5
Dezube, B.6
-
30
-
-
0018822074
-
The action of caffeine on X-irradiated HeLa cells. IV. Progression delays and enhanced cell killing at high caffeine concentrations
-
Tolmach LJ, Busse PM. 1980. The action of caffeine on X-irradiated HeLa cells. IV. Progression delays and enhanced cell killing at high caffeine concentrations Radiation Research 82:374-392.
-
(1980)
Radiation Research
, vol.82
, pp. 374-392
-
-
Tolmach, L.J.1
Busse, P.M.2
-
31
-
-
1242317867
-
Caffeine inhibits homology-directed repair of I-SecI-induced DNA double-strand breaks
-
Wang H, Boecker W, Wang H, Wang X, Guan J, Thompson LH, Nickoloff JA, Iliakis G. 2004. Caffeine inhibits homology-directed repair of I-SecI-induced DNA double-strand breaks. Oncogene 23:824-834.
-
(2004)
Oncogene
, vol.23
, pp. 824-834
-
-
Wang, H.1
Boecker, W.2
Wang, H.3
Wang, X.4
Guan, J.5
Thompson, L.H.6
Nickoloff, J.A.7
Iliakis, G.8
-
32
-
-
0029895439
-
UCN-01: A potent abrogator of G2 checkpoint function in cancer cells with disrupted p53
-
Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM. 1996. UCN-01: A potent abrogator of G2 checkpoint function in cancer cells with disrupted p53. J National Cancer Institute 88:956-965.
-
(1996)
J National Cancer Institute
, vol.88
, pp. 956-965
-
-
Wang, Q.1
Fan, S.2
Eastman, A.3
Worland, P.J.4
Sausville, E.A.5
O'Connor, P.M.6
-
33
-
-
0023712476
-
The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
-
Weinert TA, Hartwell LH. 1988. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241:317-322.
-
(1988)
Science
, vol.241
, pp. 317-322
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
34
-
-
33244474612
-
Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells
-
Wendt J, Radetzki S, Haefen C, Hemmati PG, Guner D, Schulze-Osthoff K, Dorken B, Daniel PT. 2006. Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells. Oncogene 25:972-980.
-
(2006)
Oncogene
, vol.25
, pp. 972-980
-
-
Wendt, J.1
Radetzki, S.2
Haefen, C.3
Hemmati, P.G.4
Guner, D.5
Schulze-Osthoff, K.6
Dorken, B.7
Daniel, P.T.8
-
35
-
-
0036146085
-
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
-
Xu B, Kim S, Lim DS, Kastan MB. 2002. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Molecular and Cellular Biology 22:1049-1059.
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 1049-1059
-
-
Xu, B.1
Kim, S.2
Lim, D.S.3
Kastan, M.B.4
-
36
-
-
16044371194
-
Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase
-
Yao SL, Akhtar AJ, McKenna KA, Bedi GC, Sidransky D, Mabry M, Ravi R, Collector MI, Jones RJ, Sharkis SJ, Fuchs EJ, Bedi A. 1996. Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase. Nature Medicine 2:1140-1143.
-
(1996)
Nature Medicine
, vol.2
, pp. 1140-1143
-
-
Yao, S.L.1
Akhtar, A.J.2
McKenna, K.A.3
Bedi, G.C.4
Sidransky, D.5
Mabry, M.6
Ravi, R.7
Collector, M.I.8
Jones, R.J.9
Sharkis, S.J.10
Fuchs, E.J.11
Bedi, A.12
-
37
-
-
33646819364
-
Induced apoptosis of cancer cells by antisense ATM gene therapy
-
Yi HK, Chang SH, Lee DY, Kim JS, Hwang PH. 2000. Induced apoptosis of cancer cells by antisense ATM gene therapy. Journal of Korean Cancer Association 32:339-349.
-
(2000)
Journal of Korean Cancer Association
, vol.32
, pp. 339-349
-
-
Yi, H.K.1
Chang, S.H.2
Lee, D.Y.3
Kim, J.S.4
Hwang, P.H.5
-
38
-
-
0032190082
-
Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1
-
Zeng Y, Forbes KC, Wu Z, Moreno S, Piwnica-Worms H, Enoch T. 1998. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature 395:507-510.
-
(1998)
Nature
, vol.395
, pp. 507-510
-
-
Zeng, Y.1
Forbes, K.C.2
Wu, Z.3
Moreno, S.4
Piwnica-Worms, H.5
Enoch, T.6
|