Sparing of methionine requirements: Evaluation of human data takes sulfur amino acids beyond protein

Journal of Nutrition

Volumn 136, Issue 6, 2006, Pages

  Fukagawa, Naomi K ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Amino acids; Cysteine; Methionine; Methyl groups; Sulfur amino acid requirement

Indexed keywords

ACETYLCYSTEINE; BETAINE; CARBOXYLIC ACID DERIVATIVE; CHOLINE; CYSTEINE; LEVO 2 OXOTHIAZOLIDINE 4 CARBOXYLIC ACID; METHIONINE; PHOSPHATIDYLCHOLINE; S ADENOSYLMETHIONINE; S METHYLMETHIONINE; SULFUR; SULFUR AMINO ACID; UNCLASSIFIED DRUG;

CARDIOVASCULAR DISEASE; CHRONIC DISEASE; CONFERENCE PAPER; DEMENTIA; DNA TRANSCRIPTION; HUMAN; IMMUNOMODULATION; IN VIVO STUDY; LIVER CIRRHOSIS; MEDICAL ASSESSMENT; NUTRITIONAL REQUIREMENT; PROTEIN SYNTHESIS; RNA TRANSLATION; TOXICITY;

EID: 33646789154     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.6.1676s     Document Type: Conference Paper

References (69)

1. Baker DH. Comparative species utilization and toxicity of sulfur amino acids. J Nutr. 2006;136(Suppl):1617S-5S.
2. Augspurger NR, Scherer CS, Garrow TA, Baker DH. Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens. J Nutr. 2005;135:1712-7.
3. Rose WC, Johnson JE, Haines WJ. The amino acid requirements of man. I: the role of valine and methionine. J Biol Chem. 1950;182:541-56.
4. Rose WC, Wixom RL. The amino acid requirements of man. XII. The sparing effect of cysteine on the methionine requirements. J Biol Chem. 1955;216:763-74.
5. Young VR, Borgonha S. Nitrogen and amino acid requirements: The Massachusetts Institute of Technology amino acid requirement pattern. J Nutr. 2000;130:1841S-9S.
6. Raguso C, Ajami AM, Gleason R, Young VR. Effect of cystine intake on methionine kinetics and oxidation, using oral tracers of methionine and cystine in healthy adults. Am J Clin Nutr. 1997;66:283-92.
7. Raguso C, Regan MM, Young VR. Cysteine kinetics and oxidation at different intakes of methionine and cystine in young adults. Am J Clin Nutr. 2000;71:491-9.
8. Stipanuk MH. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu Rev Nutr. 2004;24:539-77.
9. Di Buono M, Wykes LJ, Ball RO, Pencharz PB. Dietary cysteine reduces the methionine requirement in men. Am J Clin Nutr. 2001;74:761-6.
10. 13C]phenylalanine. Am J Clin Nutr. 2001;74:756-60.
11. Di Buono M, Wykes LJ, Cole DEC, Ball RO, Pencharz PB. Regulation of sulfur amino acid metabolism in men in response to changes in sulfur amino acid intakes. J Nutr. 2003;133:733-9.
12. Ball RO, Courtney-Martin G, Pencharz PB. The invivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J Nutr. 2006;136(Suppl):1682S-93S.
13. Wiseman M. The feast of the assumptions. Public Health Nutr. 2004;7:385.
14. 3]methionine kinetics in humans: methionine conservation and cystine sparing. Am J Physiol Endocrinol Metab. 1990;258:E790-8.
15. 13C]methionine as a tracer. Am J Clin Nutr. 1991;54:377-85.
16. Hiramatsu T, Fukagawa NK, Marchini JS, Cortiella J, Yu Y-M, Chapman TE, Young VR. Methionine and cysteine kinetics at different intakes of cystine in healthy adult men. Am J Clin Nutr. 1994;60:525-33.
17. Fukagawa NK, Yu Y-M, Young VR. Methionine and cysteine kinetics at different intakes of methionine and cystine in elderly men and women. Am J Clin Nutr. 1998;68:380-8.
18. Raguso C, Pereira P, Young VR. A tracer investigation of the obligatory oxidative amino acid losses in healthy young adults.AmJ Clin Nutr. 1999;70:474-83.
19. Kurpad AV, Regan MM, Varalakshmi S, Vasudevan J, Gnanou J, Raj T, Young VR. Daily methionine requirements of healthy Indian men, measured by a 24-h indicator amino acid oxidation and balance technique. Am J Clin Nutr. 2003;77:1198-205.
20. Kurpad AV, Regan MM, Varalakshmi S, Gnanou J, Young VR. Daily requirement for total sulfur amino acids of chronically undernourished Indian men. Am J Clin Nutr. 2004;80:95-100.
21. Kurpad AV, Regan MM, Varalakshmi S, Gnanou J, Lingappa A, Young VR. Effect of cystine on the methionine requirement of healthy Indian men determined by using the 24-h indicator amino acid balance approach. Am J Clin Nutr. 2004;80:1526-35.
22. Zeisel SH, Blusztajn JK. Choline and Human Nutrition. Annu Rev Nutr. 1994;14:269-96.
23. Fukagawa NK, Galbraith RA. Advancing age and other factors influencing the balance between amino acid requirements and toxicity. J Nutr. 2004;134:1569S-1574S.
24. Niculescu MD, Zeisel SH. Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J Nutr. 2002;132:2333S-2335S.
25. Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003;133:4135-8.
26. Melse-Boonstra A, Holm PI, Ueland PM, Olthof M, Clarke R, Verhoef P. Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations. Am J Clin Nutr. 2005;81:1378-82.
27. Olthof MR, Brink EJ, Katan MB, Verhoef P. Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men. Am J Clin Nutr. 2005;82:111-7.
28. Townsend DM, Tew KD, Tapiero H. Sulfur containing amino acids and human disease. Biomed Pharmacother. 2004;58:47-55.
29. Van den Veyver IB. Genetic effects of methylation diets. Annu Rev Nutr. 2002;22:255-82.
30. Ulrey CL, Liu L, Andrews LG, Tollefsbol TO. The impact of metabolism on DNA methylation. Hum Mol Genet. 2005;14:R139-47.
31. Geisel J, Schorr H, Bodis M, Isber S, Hübner U, Knapp J-P, Obeid R, Herrmann W. The vegetarian lifestyle and DNA methylation. Clin Chem Lab Med. 2005;43:1164-9.
32. Grimble RF, Grimble GK. Immunonutrition: role of sulfur amino acids, related amino acids, and polyamines. Nutrition. 1998;14:605-10.
33. Grimble RF. Nutritional modulation of immune function. Proc Nutr Soc. 2001;60:389-97.
34. Grimble RF. Sulphur amino acids and the metabolic response to cytokines. Adv Exp Med Biol. 1994;359:41-9.
35. Chung TK, Funk MA, Baker DH. L-2-Oxothiazolidine-4-carboxylate as a cysteine precursor: efficacy for growth and hepatic glutathione synthesis in chicks and rats. J Nutr. 1990;120:158-60.
36. Ackermann JM, Pegg AE, McCloskey DE. Drugs affecting the cell cycle via actions on the polyamine metabolic pathway. Prog Cell Cycle Res. 2003;5:461-8.
37. Mutch DM, Wahli W, Williamson G. Nutrigenomics and nutrigenetics: the emerging faces of nutrition. FASEB J. 2005;19:1602-16.
38. Eckel RH, York DA, Rossner S, Hubbard V, Caterson I, St.Jeor ST, Hayman LL, Mullis RM, Blair SN. Prevention conference VII: obesity, a worldwide epidemic related to heart disease and stroke: executive summary. Circulation. 2004;110:2968-75.
39. Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest. 2004;114:147-52.
40. Kirsch R, Clarkson V, Shephard EG, Marais DA, Jaffer MA, Woodburne VE, Kirsch RE, Hall PdeL. Rodent nutritional model of non-alcoholic steatohepatitis: Species, strain and sex difference studies. J Gastroenterol Hepatol. 2003;18:1272-82.
41. Zhu X, Song J, Mar M-H, Edwards LJ, Zeisel SH. Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline. Biochem J. 2003;370:987-93.
42. Song J, Da Costa KA, Fischer LM, Kohlmeier M, Kwock L, Wang S, Zeisel SH. Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J. 2005;19:1266-71.
43. Tabakoff B, Eriksson C, von Wartburg J. Methionine lowers circulating levels of acetaldehyde after ethanol ingestion. Alcohol Clin Exp Res. 1989;13:164-71.
44. Lieber CS. S-Adenosyl-L-methionine: its role in the treatment of liver disorders. Am J Clin Nutr. 2002;76:1183S-7S.
45. Andersson A, Brattstrom L, Israelsson B, Isaksson A, Hultberg B. The effect of excess daily methionine intake on plasma homocysteine after a methionine loading test in humans. Clin Chim Acta. 1990;192:69-76.
46. Andersson A, Brattstrom L, Israelsson B, Isaksson A, Hamfelt A, Hultberg B. Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status. Eur J Clin Invest. 1992;22:79-87.
47. Ward M, McNulty H, McPartlin J, Strain JJ, Weir DG, Scott JM. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int J Vitam Nutr Res. 2001;71:82-6.
48. Verhoef P, van Vliet T, Olthof MR, Katan MB. A high-protein diet increases postprandial but not fasting plasma total homocysteine concentrations: a dietary controlled, crossover trial in healthy volunteers. Am J Clin Nutr. 2005;82:553-8.
49. Verhoef P, Steenge GR, Boelsma E, van Vliet T, Olthof MR, Katan MB. Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans.Am J Clin Nutr. 2004;80:674-9.
50. Troen AM, Lutgens E, Smith DE, Rosenberg IH, Selhub J. The atherogenic effect of excess methionine intake. Proc Natl Acad Sci USA. 2003;100:15089-94.
51. Selhub J. The many facets of hyperhomocysteinemia: Studies from the Framingham Cohorts. J Nutr. 2006;136(Suppl):1726S-30S.
52. Refsum H, Nurk E, Smith AD, Ueland PM, Gjesdal CG, Bjelland I, Tverdal A, Tell GS, Nygård O, Vollset SE. The Hordaland Homocysteine Study: A community-based study of homocysteine, its determinants, and associations to disease. J Nutr. 2006;136(Suppl):1731S-40S.
53. Raijmakers M, Schilders G, Roes E, Van Tits L, Hak-Lemmers H, Steegers E, Peters W. N-Acetylcysteine improves the disturbed thiol redox balance after methionine loading. Clin Sci. 2003;105:173-80.
54. Lee TT, Wang MM, Hou RCW, Chen L-J, Su R-C, Wang C-S, Tzen JTC. Enhanced methionine and cysteine levels in transgenic rice seeds by the accumulation of sesame 2S albumin. Biosci Biotechnol Biochem. 2003;67:1699-705.
55. Haulrik N, Toubro S, Dyerberg J, Stender S, Skov AR, Astrup A. Effect of protein and methionine intakes on plasma homocysteine concentrations: a 6-mo randomized controlled trial in overweight subjects. Am J Clin Nutr. 2002;76:1202-6.
56. Burgunder JM, Varriale A, Lauterburg BH. Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur J Clin Pharmacol. 1989;36:127-31.
57. Burns KE, Chu MW, Novick RJ, Fox SA, Gallo K, Martin CM, Stitt LW, Heidenheim AP, Myers ML, Moist L. Perioperative N-acetylcysteine to prevent renal dysfunction in high-risk patients undergoing CABG surgery: A randomized controlled trial. JAMA. 2005;294:342-50.
58. Patriarca S, Furfaro AL, Domenicotti C, Odetti P, Cottalasso D, Marinari UM, Pronzato MA, Traverso N. Supplementation with N-acetylcysteine and taurine failed to restore glutathione content in liver of streptozotocin-induced diabetics rats but protected from oxidative stress. Biochim Biophys Acta. 2005;1741:48-54.
59. Olsson B, Johansson M, Gabrielsson J, Bolme P. Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine. Eur J Clin Pharmacol. 1988;34:77-82.
60. Kalebic T, Kinter A, Poli G, Anderson ME, Meister A, Fauci AS. Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci USA. 1991;88:986-90.
61. Fabry M, Schaefer E, Ellis L, Kojro E, Fahrenholz F, Brandenburg D. Detection of a new hormone contact site within the insulin receptor ectodomain by the use of a novel photoreactive insulin. J Biol Chem. 1992;267:8950-6.
62. Kalayjian RC, Skowron G, Emgushov RT, Chance M, Spell SA, Borum PR, Webb LS, Mayer KH, Jackson JB, et al. A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (Procysteine) in asymptomatic HIV-infected subjects. J Acquir Immune Defic Syndr. 1994;7:369-74.
63. 13C-labeled L-2-oxothiazolidine-4-carboxylic acid: probe for precursor mobilization for glutathione synthesis. Am J Physiol Endocrinol Metab. 2000;278:E171-6.
64. Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N, Kono H, Frey W, Forman D, et al. The glutathione precursor L-2-oxothiazolidine-4- carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat. Hepatology. 2000;31:391-8.
65. Breborowicz A, Breborowicz M, Oreopoulos DG. Glucose-induced changes in the phenotype of human peritoneal mesothelial cells: Effect of L-2-oxothiazolidine carboxylic acid. Am J Nephrol. 2003;23:471-6.
66. Breborowicz A, Witowski J, Polubinska A, Pyda M, Oreopoulos D. L-2-Oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products. Nephrol Dial Transplant. 2004;19:3005-11.
67. Han MK, Kim SJ, Park YR, Shin YM, Park HJ, Park KJ, Park KH, Kim HK, Jang SI, et al. Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4- carboxylic acid, through CD38 dimerization and internalization. J Biol Chem. 2002;277:5315-21.
68. Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Park KH, Kim UH, Kim CY, Lee YC. A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma. Mol Pharmacol. 2005;68:1281-90.
69. Lee YC, Lee KS, Park SJ, Park HS, Lim JS, Park KH, Im MJ, Choi IW, Lee HK, Kim UH. Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid. FASEB J. 2004;18:1917-9.