-
1
-
-
0014545138
-
Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
-
McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol. 1969;56:111-28.
-
(1969)
Am J Pathol
, vol.56
, pp. 111-128
-
-
McCully, K.S.1
-
2
-
-
0017284939
-
The pathogenesis of coronary artery disease. A possible role for methionine metabolism
-
Wilcken DE, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest. 1976;57:1079-82.
-
(1976)
J Clin Invest
, vol.57
, pp. 1079-1082
-
-
Wilcken, D.E.1
Wilcken, B.2
-
4
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
-
Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 1995;274:1049-57.
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
5
-
-
0033853452
-
Homocysteine and cardiovascular disease: Cause or effect?
-
Brattstrom L, Wilcken DE. Homocysteine and cardiovascular disease: cause or effect? Am J Clin Nutr. 2000;72:315-23.
-
(2000)
Am J Clin Nutr
, vol.72
, pp. 315-323
-
-
Brattstrom, L.1
Wilcken, D.E.2
-
7
-
-
0023832738
-
Higher total plasma homocysteine in vitamin B12 deficiency than in heterozygosity for homocystinuria due to cystathionine beta-synthase deficiency
-
Brattstrom L, Israelsson B, Lindgarde F, Hultberg B. Higher total plasma homocysteine in vitamin B12 deficiency than in heterozygosity for homocystinuria due to cystathionine beta-synthase deficiency. Metabolism. 1988;37:175-8.
-
(1988)
Metabolism
, vol.37
, pp. 175-178
-
-
Brattstrom, L.1
Israelsson, B.2
Lindgarde, F.3
Hultberg, B.4
-
8
-
-
0032497941
-
Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
-
Brattstrom L, Wilcken DE, Ohrvik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation. 1998;98:2520-6.
-
(1998)
Circulation
, vol.98
, pp. 2520-2526
-
-
Brattstrom, L.1
Wilcken, D.E.2
Ohrvik, J.3
Brudin, L.4
-
9
-
-
0037163849
-
MTHFR 677C→T polymorphism and risk of coronary heart disease: A meta-analysis
-
Klerk M, Verhoef P, Clarke R, Blom HJ, Kok FJ, Schouten EG. MTHFR 677C→T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA. 2002;288:2023-31.
-
(2002)
JAMA
, vol.288
, pp. 2023-2031
-
-
Klerk, M.1
Verhoef, P.2
Clarke, R.3
Blom, H.J.4
Kok, F.J.5
Schouten, E.G.6
-
10
-
-
12344309062
-
Homocysteine and stroke: Evidence on a causal link from mendelian randomisation
-
Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and stroke: evidence on a causal link from mendelian randomisation. Lancet. 2005;365:224-32.
-
(2005)
Lancet
, vol.365
, pp. 224-232
-
-
Casas, J.P.1
Bautista, L.E.2
Smeeth, L.3
Sharma, P.4
Hingorani, A.D.5
-
11
-
-
0037164104
-
Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
-
Homiocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 2002;288:2015-22.
-
(2002)
JAMA
, vol.288
, pp. 2015-2022
-
-
-
12
-
-
0026533906
-
The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine
-
Selhub J, Miller JW. The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. Am J Clin Nutr. 1992;55:131-8.
-
(1992)
Am J Clin Nutr
, vol.55
, pp. 131-138
-
-
Selhub, J.1
Miller, J.W.2
-
13
-
-
0002572171
-
Epidemiological approaches to heart disease: The Framingham Study
-
Dawber TR, Meadors GF, Moore FE, Jr. Epidemiological approaches to heart disease: the Framingham Study. Am J Public Health. 1951;41:279-81.
-
(1951)
Am J Public Health
, vol.41
, pp. 279-281
-
-
Dawber, T.R.1
Meadors, G.F.2
Moore Jr., F.E.3
-
14
-
-
0027382008
-
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
-
Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA. 1993;270:2693-8.
-
(1993)
JAMA
, vol.270
, pp. 2693-2698
-
-
Selhub, J.1
Jacques, P.F.2
Wilson, P.W.3
Rush, D.4
Rosenberg, I.H.5
-
15
-
-
0028966321
-
Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis
-
Selhub J, Jacques PF, Bostom AG, D'Agostino RB, Wilson PW, Belanger AJ, O'Leary DH, Wolf PA, Schaefer EJ, Rosenberg IH. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med. 1995;332:286-91.
-
(1995)
N Engl J Med
, vol.332
, pp. 286-291
-
-
Selhub, J.1
Jacques, P.F.2
Bostom, A.G.3
D'Agostino, R.B.4
Wilson, P.W.5
Belanger, A.J.6
O'Leary, D.H.7
Wolf, P.A.8
Schaefer, E.J.9
Rosenberg, I.H.10
-
16
-
-
0033533435
-
Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: The Framingham Study
-
Bostom AG, Rosenberg IH, Silbershatz H, Jacques PF, Selhub J, D'Agostino RB, Wilson PW, Wolf PA. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study. Ann Intern Med. 1999;131:352-5.
-
(1999)
Ann Intern Med
, vol.131
, pp. 352-355
-
-
Bostom, A.G.1
Rosenberg, I.H.2
Silbershatz, H.3
Jacques, P.F.4
Selhub, J.5
D'Agostino, R.B.6
Wilson, P.W.7
Wolf, P.A.8
-
17
-
-
0033599973
-
Nonfasting plasma total homocysteine levels and allcause and cardiovascular disease mortality in elderly Framingham men and women
-
Bostom AG, Silbershatz H, Rosenberg IH, Selhub J, D'Agostino RB, Wolf PA, Jacques PF, Wilson PW. Nonfasting plasma total homocysteine levels and allcause and cardiovascular disease mortality in elderly Framingham men and women. Arch Intern Med. 1999;159:1077-80.
-
(1999)
Arch Intern Med
, vol.159
, pp. 1077-1080
-
-
Bostom, A.G.1
Silbershatz, H.2
Rosenberg, I.H.3
Selhub, J.4
D'Agostino, R.B.5
Wolf, P.A.6
Jacques, P.F.7
Wilson, P.W.8
-
18
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, Wilson PW, Wolf PA. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002;346:476-83.
-
(2002)
N Engl J Med
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
Wilson, P.W.7
Wolf, P.A.8
-
19
-
-
2342464257
-
Homocysteine as a predictive factor for hip fracture in older persons
-
McLean RR, Jacques PF, Selhub J, Tucker KL, Samelson EJ, Broe KE, Hannan MT, Cupples LA, Kiel DP. Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med. 2004;350:2042-9.
-
(2004)
N Engl J Med
, vol.350
, pp. 2042-2049
-
-
McLean, R.R.1
Jacques, P.F.2
Selhub, J.3
Tucker, K.L.4
Samelson, E.J.5
Broe, K.E.6
Hannan, M.T.7
Cupples, L.A.8
Kiel, D.P.9
-
20
-
-
0037433466
-
Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction
-
Vasan RS, Beiser A, D'Agostino RB, Levy D, Selhub J, Jacques PF, Rosenberg IH, Wilson PW. Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction. JAMA. 2003;289:1251-7.
-
(2003)
JAMA
, vol.289
, pp. 1251-1257
-
-
Vasan, R.S.1
Beiser, A.2
D'Agostino, R.B.3
Levy, D.4
Selhub, J.5
Jacques, P.F.6
Rosenberg, I.H.7
Wilson, P.W.8
-
21
-
-
11144356292
-
Relations of plasma homocysteine to left ventricular structure and function: The Framingham Heart Study
-
Sundstrom J, Sullivan L, Selhub J, Benjamin EJ, D'Agostino RB, Jacques PF, Rosenberg IH, Levy D, Wilson PW, Vasan RS. Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study. Eur Heart J. 2004;25:523-30.
-
(2004)
Eur Heart J
, vol.25
, pp. 523-530
-
-
Sundstrom, J.1
Sullivan, L.2
Selhub, J.3
Benjamin, E.J.4
D'Agostino, R.B.5
Jacques, P.F.6
Rosenberg, I.H.7
Levy, D.8
Wilson, P.W.9
Vasan, R.S.10
-
22
-
-
0035282903
-
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
-
Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum Mol Genet. 2001;10:433-43.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 433-443
-
-
Chen, Z.1
Karaplis, A.C.2
Ackerman, S.L.3
Pogribny, I.P.4
Melnyk, S.5
Lussier-Cacan, S.6
Chen, M.F.7
Pai, A.8
John, S.W.9
-
23
-
-
0028937163
-
Mice deficient in cystathionine beta-synthase: Animal models for mild and severe homocyst(e)inemia
-
USA
-
Watanabe M, Osada J, Aratani Y, Kluckman K, Reddick R, Malinow MR, Maeda N. Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia. Proc Natl Acad Sci USA. 1995;92:1585-9.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 1585-1589
-
-
Watanabe, M.1
Osada, J.2
Aratani, Y.3
Kluckman, K.4
Reddick, R.5
Malinow, M.R.6
Maeda, N.7
-
24
-
-
0029051274
-
Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits
-
Toborek M, Kopieczna-Grzebieniak E, Drozdz M, Wieczorek M. Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits. Atherosclerosis. 1995;115:217-24.
-
(1995)
Atherosclerosis
, vol.115
, pp. 217-224
-
-
Toborek, M.1
Kopieczna-Grzebieniak, E.2
Drozdz, M.3
Wieczorek, M.4
-
25
-
-
0033165666
-
Effects of folate supplementation in hyperhomocysteinemic pigs
-
Ambrosi P, Rolland PH, Bodard H, Barlatier A, Charpiot P, Guisgand G, Friggi A, Ghiringhelli O, Habib G, et al. Effects of folate supplementation in hyperhomocysteinemic pigs. J Am Coll Cardiol. 1999;34:274-9.
-
(1999)
J Am Coll Cardiol
, vol.34
, pp. 274-279
-
-
Ambrosi, P.1
Rolland, P.H.2
Bodard, H.3
Barlatier, A.4
Charpiot, P.5
Guisgand, G.6
Friggi, A.7
Ghiringhelli, O.8
Habib, G.9
-
26
-
-
0016743933
-
Homocysteine theory of arteriosclerosis
-
McCully KS, Wilson RB. Homocysteine theory of arteriosclerosis. Atherosclerosis. 1975;22:215-27.
-
(1975)
Atherosclerosis
, vol.22
, pp. 215-227
-
-
McCully, K.S.1
Wilson, R.B.2
-
27
-
-
0035107609
-
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
-
Hofmann MA, Lalla E, Lu Y, Gleason MR, Wolf BM, Tanji N, Ferran LJ Jr, Kohl B, Rao V, et al. Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J Clin Invest. 2001;107:675-83.
-
(2001)
J Clin Invest
, vol.107
, pp. 675-683
-
-
Hofmann, M.A.1
Lalla, E.2
Lu, Y.3
Gleason, M.R.4
Wolf, B.M.5
Tanji, N.6
Ferran Jr., L.J.7
Kohl, B.8
Rao, V.9
-
28
-
-
0035830389
-
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury
-
Morita H, Kurihara H, Yoshida S, Saito Y, Shindo T, Oh-Hashi Y, Kurihara Y, Yazaki Y, Nagai R. Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury. Circulation. 2001;103:133-9.
-
(2001)
Circulation
, vol.103
, pp. 133-139
-
-
Morita, H.1
Kurihara, H.2
Yoshida, S.3
Saito, Y.4
Shindo, T.5
Oh-Hashi, Y.6
Kurihara, Y.7
Yazaki, Y.8
Nagai, R.9
-
29
-
-
0035573652
-
Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice
-
Zhou J, Moller J, Danielsen CC, Bentzon J, Ravn HB, Austin RC, Falk E. Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:1470-6.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1470-1476
-
-
Zhou, J.1
Moller, J.2
Danielsen, C.C.3
Bentzon, J.4
Ravn, H.B.5
Austin, R.C.6
Falk, E.7
-
30
-
-
0028907052
-
Hyperhomocysteinemia-induced vascular damage in the minipig. Captopril-hydrochlorothiazide combination prevents elastic alterations
-
Rolland PH, Friggi A, Barlatier A, Piquet P, Latrille V, Faye MM, Guillou J, Charpiot P, Bodard H, et al. Hyperhomocysteinemia-induced vascular damage in the minipig. Captopril-hydrochlorothiazide combination prevents elastic alterations. Circulation. 1995;91:1161-74.
-
(1995)
Circulation
, vol.91
, pp. 1161-1174
-
-
Rolland, P.H.1
Friggi, A.2
Barlatier, A.3
Piquet, P.4
Latrille, V.5
Faye, M.M.6
Guillou, J.7
Charpiot, P.8
Bodard, H.9
-
31
-
-
0021201587
-
Adverse effects of excessive consumption of amino acids
-
Benevenga NJ, Steele RD. Adverse effects of excessive consumption of amino acids. Annu Rev Nutr. 1984;4:157-81.
-
(1984)
Annu Rev Nutr
, vol.4
, pp. 157-181
-
-
Benevenga, N.J.1
Steele, R.D.2
-
32
-
-
0345598869
-
The atherogenic effect of excess methionine intake
-
USA
-
Troen AM, Lutgens E, Smith DE, Rosenberg IH, Selhub J. The atherogenic effect of excess methionine intake. Proc Natl Acad Sci USA. 2003;100:15089-94.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 15089-15094
-
-
Troen, A.M.1
Lutgens, E.2
Smith, D.E.3
Rosenberg, I.H.4
Selhub, J.5
-
33
-
-
1342309318
-
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
-
Toole JF, Malinow MR, Chambless LE, Spence JD, Pettigrew LC, Howard VJ, Sides EG, Wang CH, Stampfer M. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA. 2004;291:565-75.
-
(2004)
JAMA
, vol.291
, pp. 565-575
-
-
Toole, J.F.1
Malinow, M.R.2
Chambless, L.E.3
Spence, J.D.4
Pettigrew, L.C.5
Howard, V.J.6
Sides, E.G.7
Wang, C.H.8
Stampfer, M.9
-
34
-
-
27644521579
-
Vitamin Intervention for Stroke Prevention trial: An efficacy analysis
-
Spence JD, Bang H, Chambless LE, Stampfer MJ. Vitamin Intervention For Stroke Prevention trial: an efficacy analysis. Stroke. 2005;36:2404-9.
-
(2005)
Stroke
, vol.36
, pp. 2404-2409
-
-
Spence, J.D.1
Bang, H.2
Chambless, L.E.3
Stampfer, M.J.4
-
35
-
-
30744464433
-
NORVIT: Randomized trial of homocysteine-lowering with B-vitamins for secondary prevention of cardiovascular disease after acute myocardial infarction
-
Bønaa KH. (2005) NORVIT: Randomized trial of homocysteine-lowering with B-vitamins for secondary prevention of cardiovascular disease after acute myocardial infarction. European Society of Cardiology Congress.
-
(2005)
European Society of Cardiology Congress
-
-
Bønaa, K.H.1
-
36
-
-
0035969545
-
Decreased rate of coronary restenosis after lowering of plasma homocysteine levels
-
Schnyder G, Roffi M, Pin R, Flammer Y, Lange H, Eberli FR, Meier B, Turi ZG, Hess OM. Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. N Engl J Med. 2001;345:1593-600.
-
(2001)
N Engl J Med
, vol.345
, pp. 1593-1600
-
-
Schnyder, G.1
Roffi, M.2
Pin, R.3
Flammer, Y.4
Lange, H.5
Eberli, F.R.6
Meier, B.7
Turi, Z.G.8
Hess, O.M.9
-
37
-
-
2942752021
-
Folate therapy and in-stent restenosis after coronary stenting
-
Lange H, Suryapranata H, De Luca G, Borner C, Dille J, Kallmayer K, Pasalary MN, Scherer E, Dambrink JH. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med. 2004;350:2673-81.
-
(2004)
N Engl J Med
, vol.350
, pp. 2673-2681
-
-
Lange, H.1
Suryapranata, H.2
De Luca, G.3
Borner, C.4
Dille, J.5
Kallmayer, K.6
Pasalary, M.N.7
Scherer, E.8
Dambrink, J.H.9
-
38
-
-
0032737365
-
Niacin treatment increases plasma homocyst(e)ine levels
-
Garg R, Malinow M, Pettinger M, Upson B, Hunninghake D. Niacin treatment increases plasma homocyst(e)ine levels. Am Heart J. 1999;138:1082-7.
-
(1999)
Am Heart J
, vol.138
, pp. 1082-1087
-
-
Garg, R.1
Malinow, M.2
Pettinger, M.3
Upson, B.4
Hunninghake, D.5
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