Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis

Molecular Carcinogenesis

Volumn 45, Issue 5, 2006, Pages 309-319

  Peng, Guang ^a   Dixon, Dan A ^b   Muga, Stephanie J ^a   Smith, Theresa J ^c   Wargovich, Michael J ^a,d  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF SOUTH CAROLINA COLLEGE OF PHARMACY   (United States)

^d South Carolina Cancer Center   (United States)

Author keywords

Colon cancer cells; COX 2; EGCG; Gene expression; MAPKs; NF B

Indexed keywords

CYCLOOXYGENASE 2; EPIGALLOCATECHIN GALLATE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHENOL;

3' UNTRANSLATED REGION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER PREVENTION; CELL PROLIFERATION; CELL STRAIN HCA 7; CELL STRAIN HT29; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TEA; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; CATECHIN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HUMANS; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TEA;

EID: 33646719549     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20166     Document Type: Article

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