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Volumn 17, Issue 5-6, 1997, Pages 411-417

Antigen-presenting cells and the selection of immunodominant epitopes

Author keywords

Antigen processing; HLA DM; MHC class II

Indexed keywords

DIMER; EPITOPE; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

EID: 0030712935     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (36)

References (51)
  • 2
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann, P. V., Forsthuber, T., Miller, A., and Sercarz, E. E., Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen, Nature, 358, 155-157, 1992.
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 3
    • 0029143546 scopus 로고
    • Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16-induced tumors
    • Feltkamp, M. C., Vreugdenhil, G. R., Vierboom, M. P., Ras, E., van der Burg, S. H., ter Schegget, J., Melief, C. J., and Kast, W. M., Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16-induced tumors, Eur. J. Immunol., 25, 2638-2642, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2638-2642
    • Feltkamp, M.C.1    Vreugdenhil, G.R.2    Vierboom, M.P.3    Ras, E.4    Van Der Burg, S.H.5    Ter Schegget, J.6    Melief, C.J.7    Kast, W.M.8
  • 4
    • 0027267589 scopus 로고
    • Suppressive effect of antibody on processing of T-cell epitopes
    • Watts, C. and Lanzavecchia, A., Suppressive effect of antibody on processing of T-cell epitopes, J. Exp. Med., 178, 1459-1463, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 1459-1463
    • Watts, C.1    Lanzavecchia, A.2
  • 5
    • 0020455106 scopus 로고
    • Requirements for the processing of antigens by antigen-presenting B cells. I. Functional comparison of B-cell tumors and macrophages
    • Chesnut, R. W., Colon, S. M., and Grey, H. M., Requirements for the processing of antigens by antigen-presenting B cells. I. Functional comparison of B-cell tumors and macrophages, J. Immunol., 129, 2382-2388, 1982.
    • (1982) J. Immunol. , vol.129 , pp. 2382-2388
    • Chesnut, R.W.1    Colon, S.M.2    Grey, H.M.3
  • 6
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto, F., Cella, M., Danieli, C., and Lanzavecchia, A., Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products, J. Exp. Med., 182, 389-400, 1995.
    • (1995) J. Exp. Med. , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 9
    • 0027181070 scopus 로고
    • Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles
    • Chicz, R. M., Urban, R. G., Gorga, J. C., Vignali, D. A. A., Lane, W. S., and Strominger, J. L., Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles, J. Exp. Med., 178, 27-47, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 27-47
    • Chicz, R.M.1    Urban, R.G.2    Gorga, J.C.3    Vignali, D.A.A.4    Lane, W.S.5    Strominger, J.L.6
  • 10
    • 0027977846 scopus 로고
    • Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide
    • Long, E. O., LaVaute, T., Pinet, V., and Jaraquemada, D., Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide, J. Immunol., 153, 1487-1494, 1994.
    • (1994) J. Immunol. , vol.153 , pp. 1487-1494
    • Long, E.O.1    LaVaute, T.2    Pinet, V.3    Jaraquemada, D.4
  • 11
    • 0027155945 scopus 로고
    • Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC
    • Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC, J. Immunol., 150, 3347-3356, 1992.
    • (1992) J. Immunol. , vol.150 , pp. 3347-3356
  • 12
    • 0026343001 scopus 로고
    • Reduction of disulfide bonds within lysosomes is a key step in antigen processing
    • Collins, D. S., Unanue, E. R., and Harding, C. V., Reduction of disulfide bonds within lysosomes is a key step in antigen processing, J. Immunol., 147, 4054-4059, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 4054-4059
    • Collins, D.S.1    Unanue, E.R.2    Harding, C.V.3
  • 13
    • 0029781197 scopus 로고    scopus 로고
    • Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide
    • Gainey, D., Short, S., and McCoy, K. L., Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide, J. Cell Physiol., 168, 248-254, 1996.
    • (1996) J. Cell Physiol. , vol.168 , pp. 248-254
    • Gainey, D.1    Short, S.2    McCoy, K.L.3
  • 14
    • 0025939316 scopus 로고
    • Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes
    • Davidson, H. W., Reid, P. A., Lanzavecchia, A., and Watts, C., Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes, Cell, 67, 105-116, 1991.
    • (1991) Cell , vol.67 , pp. 105-116
    • Davidson, H.W.1    Reid, P.A.2    Lanzavecchia, A.3    Watts, C.4
  • 15
    • 0030905131 scopus 로고    scopus 로고
    • HLA-DR-restricted presentation of purified my lein basic protein is independent of intracellular processing
    • Vergelli, M., Pinet, V., Vogt, A. B., Kalbus, M., Malnati, M., Riccio, P., Long, E. O., and Martin, R., HLA-DR-restricted presentation of purified my lein basic protein is independent of intracellular processing, Eur. J. Immunol., 27, 941-951, 1997.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 941-951
    • Vergelli, M.1    Pinet, V.2    Vogt, A.B.3    Kalbus, M.4    Malnati, M.5    Riccio, P.6    Long, E.O.7    Martin, R.8
  • 16
    • 0024498412 scopus 로고
    • Binding to Ia protects an immunogenic peptide from proteolytic degradation
    • Donermeyer, D. L. and Allen, P. M., Binding to Ia protects an immunogenic peptide from proteolytic degradation, J. Immunol., 142, 1063-1068, 1989.
    • (1989) J. Immunol. , vol.142 , pp. 1063-1068
    • Donermeyer, D.L.1    Allen, P.M.2
  • 17
    • 0029962616 scopus 로고    scopus 로고
    • MHC class II molecules function as a template for the processing of a partially processed insulin peptide into a T-cell epitope
    • Lang, Y., Forquet, F., Speck, E., Blum, J., and Delovitch, T. L., MHC class II molecules function as a template for the processing of a partially processed insulin peptide into a T-cell epitope, Diabetes, 45, 1711-1719, 1996.
    • (1996) Diabetes , vol.45 , pp. 1711-1719
    • Lang, Y.1    Forquet, F.2    Speck, E.3    Blum, J.4    Delovitch, T.L.5
  • 18
    • 0026768974 scopus 로고
    • Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs
    • Rudensky, A. Y., Preston-Hurlburt, P., Al-Ramadi, B. K., Rothbard, J., and Janeway, C. A., Jr., Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs, Nature, 359, 429-431, 1992.
    • (1992) Nature , vol.359 , pp. 429-431
    • Rudensky, A.Y.1    Preston-Hurlburt, P.2    Al-Ramadi, B.K.3    Rothbard, J.4    Janeway Jr., C.A.5
  • 19
    • 0028313992 scopus 로고
    • Assembly, transport and function of MHC class II molecules
    • Cresswell, P., Assembly, transport and function of MHC class II molecules, Annu. Rev. Immunol., 12, 259-293, 1994.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 259-293
    • Cresswell, P.1
  • 20
    • 0011720253 scopus 로고
    • Role for intracellular proteases in the processing and the transport of class II HLA antigens
    • Blum, J. S. and Cresswell, P., Role for intracellular proteases in the processing and the transport of class II HLA antigens, Proc. Natl. Acad. Sci. U.S.A., 85, 3975-3979, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 3975-3979
    • Blum, J.S.1    Cresswell, P.2
  • 21
    • 0028344898 scopus 로고
    • Endosomal aspartic proteinases are required for invariant-chain processing
    • Marić, M. A., Taylor, M. D., and Blum, J. S., Endosomal aspartic proteinases are required for invariant-chain processing, Proc. Natl. Acad. Sci. U. S.A., 91, 2171-2175, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2171-2175
    • Marić, M.A.1    Taylor, M.D.2    Blum, J.S.3
  • 22
    • 0026566332 scopus 로고
    • The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen processing
    • Riberdy, J. M. and Cresswell, P., The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen processing, J. Immunol., 148, 2586-2590, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 2586-2590
    • Riberdy, J.M.1    Cresswell, P.2
  • 23
    • 0028880008 scopus 로고
    • Self-release of CLIP in peptide loading of HLA-DR molecules
    • Kropshofer, H., Vogt, A. B., Stern, L. J., and Hämmerling, G. J., Self-release of CLIP in peptide loading of HLA-DR molecules, Science, 270, 1357-1359, 1995.
    • (1995) Science , vol.270 , pp. 1357-1359
    • Kropshofer, H.1    Vogt, A.B.2    Stern, L.J.3    Hämmerling, G.J.4
  • 25
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin, L. K. and Cresswell, P., HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading, Cell, 82, 155-165, 1995.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 26
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
    • Sherman, M. A., Weber, D. A., and Jensen, P. E., DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide, Immunity, 3, 197-205, 1995.
    • (1995) Immunity , vol.3 , pp. 197-205
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.E.3
  • 27
    • 0025056497 scopus 로고
    • Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes
    • Mellins, E., Smith, L., Arp, B., Cotner, T., Celis, E., and Pious, D., Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes, Nature, 343, 71-74, 1990.
    • (1990) Nature , vol.343 , pp. 71-74
    • Mellins, E.1    Smith, L.2    Arp, B.3    Cotner, T.4    Celis, E.5    Pious, D.6
  • 28
    • 0026724242 scopus 로고
    • MHC class II deletion mutant expresses normal levels of transgene encoded class II molecules that have abnormal conformation and impaired antigen presentation ability
    • Ceman, S., Rudersdorf, R., Long, E., and DeMars, R., MHC class II deletion mutant expresses normal levels of transgene encoded class II molecules that have abnormal conformation and impaired antigen presentation ability, J. Immunol., 49, 754-761, 1992.
    • (1992) J. Immunol. , vol.49 , pp. 754-761
    • Ceman, S.1    Rudersdorf, R.2    Long, E.3    DeMars, R.4
  • 29
    • 0028225853 scopus 로고
    • Coordinate defects in HLA class II expression and antigen presentation in bare lymphocyte syndrome
    • Kovats, S., Drover, S., Marshall, W. H., Freed, D., Whiteley, P. E., Nepom, G. T., and Blum, J. S., Coordinate defects in HLA class II expression and antigen presentation in bare lymphocyte syndrome, J. Exp. Med., 179, 2017-2022, 1994.
    • (1994) J. Exp. Med. , vol.179 , pp. 2017-2022
    • Kovats, S.1    Drover, S.2    Marshall, W.H.3    Freed, D.4    Whiteley, P.E.5    Nepom, G.T.6    Blum, J.S.7
  • 30
    • 0029092766 scopus 로고
    • Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome
    • Kovats, S., Nepom, G. T., Coleman, M., Nepom, B., Kwok, W. W., and Blum, J. S., Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome, J. Clin. Invest., 96, 217-223, 1995.
    • (1995) J. Clin. Invest. , vol.96 , pp. 217-223
    • Kovats, S.1    Nepom, G.T.2    Coleman, M.3    Nepom, B.4    Kwok, W.W.5    Blum, J.S.6
  • 31
  • 33
    • 0029853195 scopus 로고    scopus 로고
    • Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules
    • Katz, J. F., Stebbins, C., Appella, E., and Sant, A. J., Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules, J. Exp. Med., 184, 1747-1753, 1996.
    • (1996) J. Exp. Med. , vol.184 , pp. 1747-1753
    • Katz, J.F.1    Stebbins, C.2    Appella, E.3    Sant, A.J.4
  • 35
    • 0028200118 scopus 로고
    • Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes
    • Amigorena, S., Drake, J. R., Webster, P., and Mellman, I., Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes, Nature, 369, 113-119, 1994.
    • (1994) Nature , vol.369 , pp. 113-119
    • Amigorena, S.1    Drake, J.R.2    Webster, P.3    Mellman, I.4
  • 36
    • 0028970286 scopus 로고
    • Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments
    • Castellino, F. and Germain, R. N., Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments, Immunity, 2, 73-88, 1995.
    • (1995) Immunity , vol.2 , pp. 73-88
    • Castellino, F.1    Germain, R.N.2
  • 37
    • 0027370367 scopus 로고
    • Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment
    • Harding, C. V. and Geuze, H. J., Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment, J. Immunol., 151, 3988-3998, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 3988-3998
    • Harding, C.V.1    Geuze, H.J.2
  • 38
    • 0028518986 scopus 로고
    • Intracellular assembly and transport of endogenous peptide: MHC class II complexes
    • Rudensky, A. Y., Marić, M. A., Eastman, E., Shoemaker, L., DeRoos, P. C., and Blum, J. S., Intracellular assembly and transport of endogenous peptide: MHC class II complexes, Immunity, 1, 585-594, 1994.
    • (1994) Immunity , vol.1 , pp. 585-594
    • Rudensky, A.Y.1    Marić, M.A.2    Eastman, E.3    Shoemaker, L.4    DeRoos, P.C.5    Blum, J.S.6
  • 39
    • 0028285075 scopus 로고
    • Separation of subcellular compartments 3 containing distinct functional forms of MHC class II
    • Xu, Y. Q., Wandinger-Ness, A., Dalke, D. P., and Pierce, S. K., Separation of subcellular compartments 3 containing distinct functional forms of MHC class II, J. Cell Biol., 125, 595-605, 1994.
    • (1994) J. Cell Biol. , vol.125 , pp. 595-605
    • Xu, Y.Q.1    Wandinger-Ness, A.2    Dalke, D.P.3    Pierce, S.K.4
  • 40
    • 0027173503 scopus 로고
    • Exogenous antigens internalized through transferrin receptors activate CD4+ T cells
    • McCoy, K. L., Noone, M., Inman, J. K., and Stutzman, R., Exogenous antigens internalized through transferrin receptors activate CD4+ T cells, J. Immunol., 150, 1691-1704, 1993.
    • (1993) J. Immunol. , vol.150 , pp. 1691-1704
    • McCoy, K.L.1    Noone, M.2    Inman, J.K.3    Stutzman, R.4
  • 41
    • 0031568395 scopus 로고    scopus 로고
    • Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms
    • Griffin, J. P., Chu, R., and Harding, C. V., Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms, J. Immunol., 158, 1523-1532, 1997.
    • (1997) J. Immunol. , vol.158 , pp. 1523-1532
    • Griffin, J.P.1    Chu, R.2    Harding, C.V.3
  • 42
    • 0025719150 scopus 로고
    • Protelytic cleavage of ricin a chain in endosomal vesicles
    • Blum, J. S., Fiani, M. L., and Stahl, P. D., Protelytic cleavage of ricin A chain in endosomal vesicles, J. Biol. Chem., 66, 22091-22095, 1991.
    • (1991) J. Biol. Chem. , vol.66 , pp. 22091-22095
    • Blum, J.S.1    Fiani, M.L.2    Stahl, P.D.3
  • 44
    • 0031002550 scopus 로고    scopus 로고
    • Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines
    • Kovats, S., Whiteley, P. E., Concannon, P., Rudensky, A. Y., and Blum, J. S., Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines, Eur. J. Immunol., 27, 1014-1021, 1997.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1014-1021
    • Kovats, S.1    Whiteley, P.E.2    Concannon, P.3    Rudensky, A.Y.4    Blum, J.S.5
  • 45
    • 0026734563 scopus 로고
    • Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens
    • Bikoff, E. K., Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens, J. Immunol., 149, 1-8, 1992.
    • (1992) J. Immunol. , vol.149 , pp. 1-8
    • Bikoff, E.K.1
  • 46
    • 0027254482 scopus 로고
    • Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways
    • Loss, G. E. J., Elias, C. G., Fields, P. E., Ribaudo, R. K., McKisic, M., and Sant, A. J., Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways, J. Exp. Med., 178, 73-85, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 73-85
    • Loss, G.E.J.1    Elias, C.G.2    Fields, P.E.3    Ribaudo, R.K.4    McKisic, M.5    Sant, A.J.6
  • 47
    • 0030636722 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of antigens overcomes the requirement for HLA- DM in class II-restricted antigen presentation
    • Ma, C. and Blum, J. S., Receptor-mediated endocytosis of antigens overcomes the requirement for HLA-DM in class II-restricted antigen presentation, J. Immunol. Cutting Edge, 158, 1-4, 1997.
    • (1997) J. Immunol. Cutting Edge , vol.158 , pp. 1-4
    • Ma, C.1    Blum, J.S.2
  • 48
    • 0342949789 scopus 로고
    • Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
    • Lanzavecchia, A., Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes, Annu. Rev. Immunol., 99, 39-51, 1990.
    • (1990) Annu. Rev. Immunol. , vol.99 , pp. 39-51
    • Lanzavecchia, A.1
  • 49
    • 0025014816 scopus 로고
    • Co-localization of molecules involved antigen processing and presentation in an early endocytic compartment
    • Guagliardi, L. E., Koppelman, B., Blum, J. S., Mark, M. S., Cresswell, P., and Brodsky, F. M., Co-localization of molecules involved antigen processing and presentation in an early endocytic compartment. Nature, 343, 133-139, 1990.
    • (1990) Nature , vol.343 , pp. 133-139
    • Guagliardi, L.E.1    Koppelman, B.2    Blum, J.S.3    Mark, M.S.4    Cresswell, P.5    Brodsky, F.M.6
  • 50
    • 0029055938 scopus 로고
    • Antigen presentation mediated by recycling of surface HLA-DR molecules
    • Pinet, V., Vergelli, M., Martin, R., Bakke, O., and Long, E. O., Antigen presentation mediated by recycling of surface HLA-DR molecules, Nature, 375, 603-606, 1995.
    • (1995) Nature , vol.375 , pp. 603-606
    • Pinet, V.1    Vergelli, M.2    Martin, R.3    Bakke, O.4    Long, E.O.5
  • 51
    • 0025071238 scopus 로고
    • Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments
    • Reid, P. A. and Watts, C., Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments, Nature, 346, 655-657, 1990.
    • (1990) Nature , vol.346 , pp. 655-657
    • Reid, P.A.1    Watts, C.2


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