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Volumn 15, Issue 22, 1996, Pages 6144-6154

Editing of the HLA-DR-peptide repertoire by HLA-DM

Author keywords

Antigen presentation; Kinetic proofreading; Mass spectrometry; MHC class II; Peptide binding assay

Indexed keywords

HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0029858056     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01002.x     Document Type: Article
Times cited : (239)

References (52)
  • 1
    • 0021064860 scopus 로고
    • Production and characterization of monoclonal antibodies recognizing the α-chain subunits of human Ia alloantigens
    • Adams, T.E., Bodmer, J.G. and Bodmer, W.F. (1983) Production and characterization of monoclonal antibodies recognizing the α-chain subunits of human Ia alloantigens. Immunology, 50, 613-624.
    • (1983) Immunology , vol.50 , pp. 613-624
    • Adams, T.E.1    Bodmer, J.G.2    Bodmer, W.F.3
  • 2
    • 0028676010 scopus 로고
    • In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides
    • Avva, R.R. and Cresswell, P. (1994) In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides. Immunity, 1, 763-774.
    • (1994) Immunity , vol.1 , pp. 763-774
    • Avva, R.R.1    Cresswell, P.2
  • 3
    • 0025202076 scopus 로고
    • MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
    • Bakke, O. and Dobberstein, B. (1990) MHC class II-associated invariant chain contains a sorting signal for endosomal compartments. Cell, 63, 707-715.
    • (1990) Cell , vol.63 , pp. 707-715
    • Bakke, O.1    Dobberstein, B.2
  • 4
    • 0028233882 scopus 로고
    • Mapping functional regions in the lumenal domain of the class II-associated invariant chain
    • Bijlmakers, M.-J.E., Benaroch, P. and Ploegh, H.L. (1994) Mapping functional regions in the lumenal domain of the class II-associated invariant chain. J. Exp. Med., 180, 623-629.
    • (1994) J. Exp. Med. , vol.180 , pp. 623-629
    • Bijlmakers, M.-J.E.1    Benaroch, P.2    Ploegh, H.L.3
  • 6
    • 0030052495 scopus 로고    scopus 로고
    • Invariant chain protects class II histocotnpatibility antigens from binding intact polypeptides in the endoplasmic reticulum
    • Busch, R., Cloutier, I., Sékaly, R.-P. and Hämmerling, G.J. (1996) Invariant chain protects class II histocotnpatibility antigens from binding intact polypeptides in the endoplasmic reticulum. EMBO J., 15, 418-428.
    • (1996) EMBO J. , vol.15 , pp. 418-428
    • Busch, R.1    Cloutier, I.2    Sékaly, R.-P.3    Hämmerling, G.J.4
  • 7
    • 0022894853 scopus 로고
    • Isolation and characterization of antigen-la complexes involved in T cell recognition
    • Buus, S., Sette, A., Colon, S.M., Jenis, D.M. and Grey, H.M. (1986) Isolation and characterization of antigen-la complexes involved in T cell recognition. Cell, 47, 1071-1077.
    • (1986) Cell , vol.47 , pp. 1071-1077
    • Buus, S.1    Sette, A.2    Colon, S.M.3    Jenis, D.M.4    Grey, H.M.5
  • 8
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC related molecules and are heterogeneous in size
    • Chicz, R.M., Urban, R.G., Lane, W.S., Gorga, J.C., Stern, L.J., Vignali, D.A.A. and Strominger, J.L. (1992) Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC related molecules and are heterogeneous in size. Nature, 358, 764-768.
    • (1992) Nature , vol.358 , pp. 764-768
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.A.6    Strominger, J.L.7
  • 10
    • 0025940456 scopus 로고
    • New class II-like genes in the murine MHC
    • Cho, S., Attaya, M. and Monaco, J.J. (1991) New class II-like genes in the murine MHC. Nature, 353, 573-576.
    • (1991) Nature , vol.353 , pp. 573-576
    • Cho, S.1    Attaya, M.2    Monaco, J.J.3
  • 11
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin, L.K. and Cresswell, P. (1995) HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell. 82, 155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 12
    • 0028217255 scopus 로고
    • The HLA-DMA gene is required for the formation of stable class II/peptide complexes
    • Fling, S.P., Arp, B. and Pious, D. (1994) The HLA-DMA gene is required for the formation of stable class II/peptide complexes. Nature, 368, 554-558.
    • (1994) Nature , vol.368 , pp. 554-558
    • Fling, S.P.1    Arp, B.2    Pious, D.3
  • 13
    • 0027489002 scopus 로고
    • The segment of invariant chain that is critical for association with MHC class II molecules contains the sequence of a peptide eluted from class II polypeptides
    • Freisewinkel, I.M. Schenck, K. and Koch, N. (1993) The segment of invariant chain that is critical for association with MHC class II molecules contains the sequence of a peptide eluted from class II polypeptides. Proc. Natl Acad. Sci. USA, 90, 9703-9706.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 9703-9706
    • Freisewinkel, I.M.1    Schenck, K.2    Koch, N.3
  • 14
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain, R.N. (1994) MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell, 76, 287-299.
    • (1994) Cell , vol.76 , pp. 287-299
    • Germain, R.N.1
  • 15
    • 0027303736 scopus 로고
    • Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules
    • Germain, R. and Rinker, Jr. A.G. (1993) Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules. Nature, 363, 725-728.
    • (1993) Nature , vol.363 , pp. 725-728
    • Germain, R.1    Rinker Jr., A.G.2
  • 16
    • 0000846523 scopus 로고
    • The structure of HLA-DR3 complexed with CLIP, an intermediate in peptide loading
    • Ghosh, P., Amaya, M., Mellins, E. and Wiley, D.C. (1995) The structure of HLA-DR3 complexed with CLIP, an intermediate in peptide loading. Nature, 387, 457-462.
    • (1995) Nature , vol.387 , pp. 457-462
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 17
    • 0026706746 scopus 로고
    • Identification of a motif for HLA-DR1 binding peptides using M13 display libraries
    • Hammer, J., Takacs, B. and Sinigaglia, F. (1992) Identification of a motif for HLA-DR1 binding peptides using M13 display libraries. J. Exp. Med., 176, 1007-1013.
    • (1992) J. Exp. Med. , vol.176 , pp. 1007-1013
    • Hammer, J.1    Takacs, B.2    Sinigaglia, F.3
  • 20
    • 0026093582 scopus 로고
    • A new human class-II related locus, DM
    • Kelly, A.P., Monaco, J.J., Cho, S. and Trowsdale, J. (1991) A new human class-II related locus, DM. Nature, 353, 571-573.
    • (1991) Nature , vol.353 , pp. 571-573
    • Kelly, A.P.1    Monaco, J.J.2    Cho, S.3    Trowsdale, J.4
  • 22
    • 0025939201 scopus 로고
    • Self and foreign peptides interact with intact and disassembled MHC class II antigen HLA-DR via Trp pockets
    • Kropshofer, H., Bohlinger, I., Max, H. and Kalbacher, H. (1991) Self and foreign peptides interact with intact and disassembled MHC class II antigen HLA-DR via Trp pockets. Biochemistry, 30, 9177-9187.
    • (1991) Biochemistry , vol.30 , pp. 9177-9187
    • Kropshofer, H.1    Bohlinger, I.2    Max, H.3    Kalbacher, H.4
  • 23
    • 0026517868 scopus 로고
    • Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif
    • Kropshofer, H., Max, H., Müller, C.A., Hesse, F., Stevanovic, S., Jung, G. and Kalbacher, H. (1992) Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif. J. Exp. Med., 175, 1799-1803.
    • (1992) J. Exp. Med. , vol.175 , pp. 1799-1803
    • Kropshofer, H.1    Max, H.2    Müller, C.A.3    Hesse, F.4    Stevanovic, S.5    Jung, G.6    Kalbacher, H.7
  • 24
    • 0027500866 scopus 로고
    • Self-peptides from four HLA-DR alleles share hydrophobic anchor residues near the N-terminus including proline as a stop-signal for trimming
    • Kropshofer, H., Max, H., Halder, T., Kalbus, M., Müller, C.A. and Kalbacher, H. (1993) Self-peptides from four HLA-DR alleles share hydrophobic anchor residues near the N-terminus including proline as a stop-signal for trimming. J. Immunol., 151, 4732-4142.
    • (1993) J. Immunol. , vol.151 , pp. 4732-14142
    • Kropshofer, H.1    Max, H.2    Halder, T.3    Kalbus, M.4    Müller, C.A.5    Kalbacher, H.6
  • 25
    • 0029114962 scopus 로고
    • Structural features of invariant chain CLIP region controlling rapid release from HLA-DR molecules and inhibition of peptide binding
    • Kropshofer, H., Vogt, A.B. and Hammerling, G.J. (1995a) Structural features of invariant chain CLIP region controlling rapid release from HLA-DR molecules and inhibition of peptide binding. Proc. Natl Acad Sci. USA, 92, 8313-8317.
    • (1995) Proc. Natl Acad Sci. USA , vol.92 , pp. 8313-8317
    • Kropshofer, H.1    Vogt, A.B.2    Hammerling, G.J.3
  • 26
    • 0028880008 scopus 로고
    • Self-release of CLIP in peptide loading of HLA-DR molecules
    • Kropshofer, H., Vogt, A.B., Stern, L.J. and Hammerling, G.J. (1995b) Self-release of CLIP in peptide loading of HLA-DR molecules. Science, 270, 1357-1359.
    • (1995) Science , vol.270 , pp. 1357-1359
    • Kropshofer, H.1    Vogt, A.B.2    Stern, L.J.3    Hammerling, G.J.4
  • 27
    • 0018937455 scopus 로고
    • Two populations of Ia-like molecules on a human B cell line
    • Lampson, L.A. and Levy, R. (1980) Two populations of Ia-like molecules on a human B cell line. J. Immunol., 125, 293-299.
    • (1980) J. Immunol. , vol.125 , pp. 293-299
    • Lampson, L.A.1    Levy, R.2
  • 28
    • 0028789975 scopus 로고
    • The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
    • Lindstedt, R., Liljedahl, M., Péléraux, A., Peterson, P.A. and Karlsson, L. (1995) The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity, 3, 561-572.
    • (1995) Immunity , vol.3 , pp. 561-572
    • Lindstedt, R.1    Liljedahl, M.2    Péléraux, A.3    Peterson, P.A.4    Karlsson, L.5
  • 30
    • 0028820625 scopus 로고
    • A lysosomal targeting signal in the cytoplasmic tail of the β chain directs HLA-DM to MHC class II compartments
    • Marks, M.S., Roche, P.A., van Donselaar, E., Woodruff, L., Peters, P.J. and Bonifacino, J.S. (1995) A lysosomal targeting signal in the cytoplasmic tail of the β chain directs HLA-DM to MHC class II compartments. J. Cell Biol., 131, 351-369.
    • (1995) J. Cell Biol. , vol.131 , pp. 351-369
    • Marks, M.S.1    Roche, P.A.2    Van Donselaar, E.3    Woodruff, L.4    Peters, P.J.5    Bonifacino, J.S.6
  • 31
    • 0028350714 scopus 로고
    • An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules
    • Morris, P., Shaman, J., Attaya, M., Amaya, M., Goodman, S., Bergman, C., Monaco, J.J. and Mellins, E. (1994) An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature, 368, 551-554.
    • (1994) Nature , vol.368 , pp. 551-554
    • Morris, P.1    Shaman, J.2    Attaya, M.3    Amaya, M.4    Goodman, S.5    Bergman, C.6    Monaco, J.J.7    Mellins, E.8
  • 32
    • 0026015286 scopus 로고
    • On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs
    • O'Sullivan, D. et al. (1991) On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs. J. Immunol., 147, 2663-2670.
    • (1991) J. Immunol. , vol.147 , pp. 2663-2670
    • O'Sullivan, D.1
  • 33
    • 0028985984 scopus 로고
    • MHC ligands and peptide motifs: First listing
    • Rammensee, H.-G., Friede, T. and Stefanovic, S. (1995) MHC ligands and peptide motifs: first listing. Immunogenetics, 41, 178-228.
    • (1995) Immunogenetics , vol.41 , pp. 178-228
    • Rammensee, H.-G.1    Friede, T.2    Stefanovic, S.3
  • 34
    • 0026440236 scopus 로고
    • HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
    • Riberdy, J.M., Newcomb, J.R., Surman, M.J., Barbosa, J.A. and Cresswell, P. (1992) HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature, 360, 474-477.
    • (1992) Nature , vol.360 , pp. 474-477
    • Riberdy, J.M.1    Newcomb, J.R.2    Surman, M.J.3    Barbosa, J.A.4    Cresswell, P.5
  • 35
    • 0025331726 scopus 로고
    • Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
    • Roche, P.A. and Cresswell, P. (1990) Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature, 345, 615-618.
    • (1990) Nature , vol.345 , pp. 615-618
    • Roche, P.A.1    Cresswell, P.2
  • 36
    • 0026353496 scopus 로고
    • Proteolysis of the MHC class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules
    • Roche, P.A. and Cresswell, P. (1991) Proteolysis of the MHC class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc. Natl Acad Sci. USA, 88, 3150-3154.
    • (1991) Proc. Natl Acad Sci. USA , vol.88 , pp. 3150-3154
    • Roche, P.A.1    Cresswell, P.2
  • 37
    • 0026088251 scopus 로고
    • Formation of a nine subunit complex by HLA class II glycoproteins and the invariant chain
    • Roche, P.A., Marks, M.S. and Cresswell, P. (1991) Formation of a nine subunit complex by HLA class II glycoproteins and the invariant chain. Nature, 354, 392-394.
    • (1991) Nature , vol.354 , pp. 392-394
    • Roche, P.A.1    Marks, M.S.2    Cresswell, P.3
  • 38
    • 0028136262 scopus 로고
    • The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy
    • Romagnoli, P. and Germain, R.N. (1994) The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy. J. Exp. Med., 180, 1107-1113.
    • (1994) J. Exp. Med. , vol.180 , pp. 1107-1113
    • Romagnoli, P.1    Germain, R.N.2
  • 39
    • 0027941809 scopus 로고
    • MHC class II function preserved by low-affinity peptide interactions preceding stable binding
    • Sadegh-Nasseri, S., Stern, L.J., Wiley, D.C. and Germain, R.N. (1994) MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature, 370, 647-650.
    • (1994) Nature , vol.370 , pp. 647-650
    • Sadegh-Nasseri, S.1    Stern, L.J.2    Wiley, D.C.3    Germain, R.N.4
  • 42
    • 0027095930 scopus 로고
    • Invariant chain peptides in most HLA-DR molecules of an antigen processing mutant
    • Sette, A. et al. (1992) Invariant chain peptides in most HLA-DR molecules of an antigen processing mutant. Science, 258, 1801-1804.
    • (1992) Science , vol.258 , pp. 1801-1804
    • Sette, A.1
  • 43
    • 0028921633 scopus 로고
    • Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II
    • Sette, A., Southwood, S., Miller, J. and Apella, E. (1995) Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II. J. Exp. Med., 181, 677-683.
    • (1995) J. Exp. Med. , vol.181 , pp. 677-683
    • Sette, A.1    Southwood, S.2    Miller, J.3    Apella, E.4
  • 44
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptides
    • Sherman, M.A., Weber, D.A. and Jensen, P. (1995) DM enhances peptide binding to class II MHC by release of invariant chain-derived peptides. Immunity, 3, 197-205.
    • (1995) Immunity , vol.3 , pp. 197-205
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.3
  • 46
    • 0028899617 scopus 로고
    • The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent
    • Stebbins, C.C., Loss, Jr, G.E., Elias, C.G., Chervonsky, A. and Sant, A.J. (1995) The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent. J. Exp. Med., 181, 223-234.
    • (1995) J. Exp. Med. , vol.181 , pp. 223-234
    • Stebbins, C.C.1    Loss Jr., G.E.2    Elias, C.G.3    Chervonsky, A.4    Sant, A.J.5
  • 47
    • 0028348369 scopus 로고
    • Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
    • Stern, L.J., Brown, J.H., Jardetzky, T.S., Gorga, J.C., Urban, R.G., Strominger, J.L. and Wiley, D.C. (1994) Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature, 368, 215-221.
    • (1994) Nature , vol.368 , pp. 215-221
    • Stern, L.J.1    Brown, J.H.2    Jardetzky, T.S.3    Gorga, J.C.4    Urban, R.G.5    Strominger, J.L.6    Wiley, D.C.7
  • 48
    • 0028240914 scopus 로고
    • Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH
    • Urban, R.G., Chicz, R.M. and Strominger, J.L. (1994) Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH. J. Exp. Med., 180, 751-755.
    • (1994) J. Exp. Med. , vol.180 , pp. 751-755
    • Urban, R.G.1    Chicz, R.M.2    Strominger, J.L.3
  • 51
    • 0028867141 scopus 로고
    • Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR
    • Vogt, A.B., Stern, L.J., Amshoff, C., Dobberstein, B., Hammerling, G.J. and Kropshofer, H. (1995) Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR. J. Immunol., 155, 4757-4765.
    • (1995) J. Immunol. , vol.155 , pp. 4757-4765
    • Vogt, A.B.1    Stern, L.J.2    Amshoff, C.3    Dobberstein, B.4    Hammerling, G.J.5    Kropshofer, H.6


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