Crystal structure of mouse H2-M

Immunity

Volumn 9, Issue 3, 1998, Pages 385-393

  Fremont, Daved H ^a   Crawford, Frances ^b   Marrack, Philippa ^b,c   Hendrickson, Wayne A ^d   Kappler, John ^b,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CONCANAVALIN A; HLA DM ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METHIONINE; SELENOMETHIONINE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; BACULOVIRUS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENDOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0032167447     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80621-4     Document Type: Article

References (52)

1. Abrahams, J.P., and Leslie, A.G. (1996). Methods used in the structure determination of bovine mitochondrial F1-ATPase. Acta Crystallogr. D 52, 30-42.
2. Albert, L.J., Ghumman, B., and Watts, T.H. (1996). Effect of HLA-DM transfection on hen egg lysozyme presentation by T2.Ak cells. J. Immunol. 157, 2247-2255.
3. Avva, R.R., and Cresswell, P. (1994). In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides. Immunity 1, 763-774.
4. + T cells. Crit. Rev. Immunol. 16, 359-379.
5. Brooks, A.G., Campbell, P.L., Reynolds, P., Gautam, A.M., and McCluskey, J. (1994). Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes. J. Immunol. 153, 5382-5392.
6. Brown, J.H., Jardetzky, T.S., Gorga, J.C., Stern, L.J., Urban, R.G., Strominger, J.L., and Wiley, D.C. (1993). Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364, 33-39.
7. Brunger, A.T., Kuriyan, J., and Karplus, M. (1987). Crystallographic R-factor refinement by molecular dynamics. Science 235, 458-460.
8. Burmeister, W.P., Gastinel, L.N., Simister, N.E., Slum, M.L., and Bjorkman, P.J. (1994). Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor. Nature 372, 336-343.
9. Busch, R., and Mellins, E.D. (1996). Developing and shedding inhibitions: how class II MHC molecules reach maturity. Curr. Opin. Immunol. 8, 51-58.
10. Carson, M. (1987). Ribbon models of macromolecules. J. Mol. Graph. 5, 103-106.
11. Castano, A.R., Tangri, S., Miller, J.E., Holcombe, H.R., Jackson, M.R., Huse, W.D., Kronenberg, M., and Peterson, P.A. (1995). Peptide binding and presentation by mouse CD1. Science 269, 223-226.
12. Collaborative Computational Project (1994). The CCP4 suite programs for protein crystallography. Acta Crystallogr. D 50, 760-763.
13. Connolly, M.L. (1993). The molecular surface package. J. Mol. Graph. 11, 139-141.
14. Copier, J., Kleijmeer, M.J., Ponnambalam, S., Oorschot, V., Potter, P., Trowsdale, J., and Kelly, A. (1996).Targeting signal and subcellular compartments involved in the intracellular trafficking of HLA-DMB. J. Immunol. 157, 1017-1027.
15. Cuthbert, J.A. (1997). Iron, HFE, and hemochromatosis update. J. Investig. Med. 45, 518-529.
16. Denzin, L.K., Hammond, C., and Cresswell, P. (1996). HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J. Exp. Med. 184, 2153-2165.
17. Denzin, L.K., Robbins, N.F., Carboy-Newcomb, C., and Cresswell, P. (1994). Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells. Immunity 1, 595-606.
18. Denzin, L.K., Sant'Angelo, D.B., Hammond, C., Surman, M.J., and Cresswell, P. (1997). Negative regulation by HLA-DO of MHC class II-restricted antigen processing. Science 278, 106-109.
19. Fremont, D.H., Hendrickson, W.A., Marrack, P., and Kappler, J. (1996). Structures of a class II MHC molecule with covalently bound single peptides. Science 272, 1001-1004.
20. Fremont, D.H., Matsumura, M., Stura, E.A., Peterson, P.A., and Wilson, I.A. (1992). Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science 257, 919-927.
21. Fremont, D.H., Monnaie, D., Nelson, C.A., Hendrickson, W.A., and Unanue, E.R. (1998). Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity 8, 305-317.
22. Fung-Leung, W.P., Surh, C.D., Liljedahl, M., Pang, J., Leturcq, D., Peterson, P.A., Webb, S.R., and Karlsson, L. (1996). Antigen presentation and T cell development in H2-M-deficient mice. Science 271, 1278-1281.
23. Ghosh, P., Amaya, M., Mellins, E., and Wiley, D.C. (1995). The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 378, 457-462.
24. Green, J.M., and Pierce, S.K. (1996). Class II antigen processing compartments and the function of HLA-DM. Int. Rev. Immunol. 13, 209-219.
25. Guerra, C.B., Busch, R., Doebele, R.C., Liu, W., Sawada, T., Kwok, W.W., Chang, M.D., and Mellins, E.D. (1998). Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization. J. Immunol. 160, 4289-4297.
26. Jones, T.A. (1978). A graphical model building and refinement system for macromolecules. J. Appl. Crystallogr. 11, 268-272.
27. Joyce, S., Woods, A.S., Yewdell, J.W., Bennink, J.R., De Silva, A.D., Boesteanu, A., Balk, S.P., Cotter, R.J., and Brutkiewicz, R.R. (1998). Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 279, 1541-1544.
28. Kabsch, W., and Sander, C. (1983). Dictionary of protein secondary structure: pattern recognition of hydrogen bonded and geometrical features. Biopolymers 22, 2577-2637.
29. Kappler, J., White, J., Kozono, H., Clements, J., and Marrack, P. (1994). Binding of a soluble αβ T cell receptor to superantigen/MHC ligands. Proc. Natl. Acad. Sci. USA 91, 8462-8466.
30. Karlsson, L., Peleraux, A., Lindstedt, R., Liljedahl, M., and Peterson, P.A. (1994). Reconstitution of an operational class II MHC compartment in nonantigen-presenting cells. Science 266, 1569-1573.
31. Kelly, A., and Trowsdale, J. (1994). Novel genes in the human major histocompatibility complex class-II region. Int. Arch. Allergy Immunol. 103, 11-15.
32. Kozono, H., White, J., Clements, J., Marrack, P., and Kappler, J.W. (1994). Functional soluble major histocompatibility complex proteins with covalently bound peptides. Nature 369, 151-154.
33. Lebron, J.A., Bennett, M.J., Vaughn, D.E., Chirino, A.J., Snow, P.M., Mintier, G.A., Feder, J.N., and Bjorkman, P.J. (1998). Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell 93, 111-123.
34. Liljedahl, M., Winqvist, O., Surh, C.D., Wong, P., Ngo, K., Teyton, L., Peterson, P.A., Brunmark, A., Rudensky, A.Y., Fung-Leung, W.P., et al. (1998). Altered antigen presentation in mice lacking H2-O. Immunity 8, 233-243.
35. Lindstedt, R., Liljedahl, M., Peleraux, A., Peterson, P.A., and Karlsson, L. (1995). The class II MHC molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity 3, 561-572.
36. Miyazaki, T., Wolf, P., Tourne, S., Waltzinger, C., Dierich, A., Barois, N., Ploegh, H., Benoist, C., and Mathis, D. (1996). Mice lacking H2-M complexes, enigmatic elements of the class II MHC peptide-loading pathway. Cell 84, 531-541.
37. Morris, P., Shaman, J., Attaya, M., Amaya, M., Goodman, S., Bergman, C., Monaco, J.J., and Mellins, E. (1994). An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature 368, 551-554.
38. Nicholls, A., Sharp, K.A., and Honig, B. (1991). Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins: Struct. Funct. Genet. 11, 281-296.
39. Otwinowski, Z., and Minor, W. (1997). Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326.
40. Park, S.J., Sadegh-Nasseri, S., and Wiley, D.C. (1995). Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1. Proc. Natl. Acad. Sci. USA 92, 11289-11293.
41. Peleraux, A., Karlsson, L., Chambers, J., and Peterson, P.A. (1996). Genomic organization of a mouse class II MHC region including the H2-M and Lmp2 loci. Immunogenetics 43, 204-214.
42. Radley, E., Alderton, R.P., Kelly, A., Trowsdale, J., and Beck, S. (1994). Genomic organization of HLA-DMA and HLA-DMB. Comparison of the gene organization of all six class II families in the human major histocompatibility complex. J. Biol. Chem. 269, 18834-18838.
43. Raghavan, M., and Bjorkman, P.J. (1996). Fc receptors and their interactions with immunoglobulins. Annu. Rev. Cell. Dev. Biol. 12, 181-220.
44. Riberdy, J.M., Newcomb, J.R., Surman, M.J., Barbosa, J.A., and Cresswell, P. (1992). HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 360, 474-477.
45. Romagnoli, P., and Germain, R.N. (1994). The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy. J. Exp. Med. 180, 1107-1113.
46. Sanderson, F., Thomas, C., Neefjes, J., and Trowsdale, J. (1996). Association between HLA-DM and HLA-DR in vivo. Immunity 4, 87-96.
47. Sloan, V.S., Cameron, P., Porter, G., Gammon, M., Amaya, M., Mellins, E., and Zaller, D.M. (1995). Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375, 802-806.
48. Smith, G.P., Dabhi, V.M., Pamer, E.G., and Lindahl, K.F. (1994). Peptide presentation by the MHC class Ib molecule, H2-M3. Int. Immunol. 6, 1917-1926.
49. Ullrich, H.J., Doring, K., Gruneberg, U., Jahnig, F., Trowsdale, J., and van Ham, S.M. (1997). Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH. Proc. Natl. Acad. Sci. USA 94, 13163-13168.
50. Unanue, E.R. (1992). Cellular studies on antigen presentation by class II MHC molecules. Curr. Opin. Immunol. 4, 63-69.
51. Weenink, S.M., and Gautam, A.M. (1997). Antigen presentation by class II MHC molecules. Immunol. Cell Biol. 75, 69-81.
52. Zeng, Z., Castano, A.R., Segelke, B.W., Stura, E.A., Peterson, P.A., and Wilson, I.A. (1997). Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 277, 339-345.