LDL induces Saos2 osteoblast death via Akt pathways responsive to a neutral sphingomyelinase inhibitor

Journal of Cellular Biochemistry

Volumn 98, Issue 3, 2006, Pages 661-671

  Klein, Benjamin Y ^a   Kerem, Zohar ^b   Rojansky, Nathan ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Akt PKB; Atherosclerosis; Co morbidity; LDL; Osteoporosis; Sphyngomyelinase; Src kinase

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 8 INHIBITOR; CASPASE 9; CERAMIDE; GLYCOGEN SYNTHASE KINASE 3; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SCYPHOSTATIN; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

AGING; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CELL DEATH; CELL SURVIVAL; COMORBIDITY; CONTROLLED STUDY; ENZYME INACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MITOCHONDRIAL RESPIRATION; OSTEOBLAST; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RISK FACTOR;

AMIDES; BCL-X PROTEIN; CELL DEATH; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; LIPOPROTEINS, LDL; OSTEOBLASTS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRONES; SPHINGOMYELIN PHOSPHODIESTERASE; SRC-FAMILY KINASES;

EID: 33646567843     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20807     Document Type: Article

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