메뉴 건너뛰기




Volumn 307, Issue 1, 2005, Pages 1-14

CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity

Author keywords

AKT; CSK; ERK; FYN; Integrin; Migration; Neurite outgrowth; NGF; PC12 cells; RAC; RAS; SRC; YES

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN KINASE YES; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RAC PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 19544380210     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.02.029     Document Type: Article
Times cited : (32)

References (46)
  • 1
    • 0035071323 scopus 로고    scopus 로고
    • P190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
    • M.R. Brouns, S.F. Matheson, and J. Settleman p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation Nat. Cell Biol. 3 2001 361 367
    • (2001) Nat. Cell Biol. , vol.3 , pp. 361-367
    • Brouns, M.R.1    Matheson, S.F.2    Settleman, J.3
  • 2
    • 0033591229 scopus 로고    scopus 로고
    • The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells
    • H. Yamashita, S. Avraham, S. Jiang, I. Dikic, and H. Avraham The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells J. Biol. Chem. 274 1999 15059 15065
    • (1999) J. Biol. Chem. , vol.274 , pp. 15059-15065
    • Yamashita, H.1    Avraham, S.2    Jiang, S.3    Dikic, I.4    Avraham, H.5
  • 5
    • 0030907924 scopus 로고    scopus 로고
    • Signal transduction by the neurotrophin receptors
    • D.R. Kaplan, and F.D. Miller Signal transduction by the neurotrophin receptors Curr. Opin. Cell Biol. 9 1997 213 221
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 213-221
    • Kaplan, D.R.1    Miller, F.D.2
  • 6
    • 0032418850 scopus 로고    scopus 로고
    • Identification and characterization of novel substrates of Trk receptors in developing neurons
    • X. Qian, A. Riccio, Y. Zhang, and D.D. Ginty Identification and characterization of novel substrates of Trk receptors in developing neurons Neuron 21 1998 1017 1029
    • (1998) Neuron , vol.21 , pp. 1017-1029
    • Qian, X.1    Riccio, A.2    Zhang, Y.3    Ginty, D.D.4
  • 7
    • 0033376412 scopus 로고    scopus 로고
    • Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3
    • J.I. MacDonald, J.M. Verdi, and S.O. Meakin Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3 J. Mol. Neurosci. 13 1999 141 158
    • (1999) J. Mol. Neurosci. , vol.13 , pp. 141-158
    • MacDonald, J.I.1    Verdi, J.M.2    Meakin, S.O.3
  • 8
    • 0033515534 scopus 로고    scopus 로고
    • The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. a model for discriminating proliferation and differentiation
    • S.O. Meakin, J.I. MacDonald, E.A. Gryz, C.J. Kubu, and J.M. Verdi The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation J. Biol. Chem. 274 1999 9861 9870
    • (1999) J. Biol. Chem. , vol.274 , pp. 9861-9870
    • Meakin, S.O.1    MacDonald, J.I.2    Gryz, E.A.3    Kubu, C.J.4    Verdi, J.M.5
  • 9
    • 0027374486 scopus 로고
    • Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex
    • A. Obermeier, R. Lammers, K.H. Wiesmuller, G. Jung, J. Schlessinger, and A. Ullrich Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex J. Biol. Chem. 268 1993 22963 22966
    • (1993) J. Biol. Chem. , vol.268 , pp. 22963-22966
    • Obermeier, A.1    Lammers, R.2    Wiesmuller, K.H.3    Jung, G.4    Schlessinger, J.5    Ullrich, A.6
  • 11
    • 0028199799 scopus 로고
    • Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses
    • R.M. Stephens, D.M. Loeb, T.D. Copeland, T. Pawson, L.A. Greene, and D.R. Kaplan Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses Neuron 12 1994 691 705
    • (1994) Neuron , vol.12 , pp. 691-705
    • Stephens, R.M.1    Loeb, D.M.2    Copeland, T.D.3    Pawson, T.4    Greene, L.A.5    Kaplan, D.R.6
  • 12
    • 0031956449 scopus 로고    scopus 로고
    • Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway
    • Y. Kita, K.D. Kimura, M. Kobayashi, S. Ihara, K. Kaibuchi, S. Kuroda, M. Ui, H. Iba, H. Konishi, U. Kikkawa, S. Nagata, and Y. Fukui Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway J. Cell Sci. 111 Pt. 7 1998 907 915
    • (1998) J. Cell Sci. , vol.111 , Issue.PART 7 , pp. 907-915
    • Kita, Y.1    Kimura, K.D.2    Kobayashi, M.3    Ihara, S.4    Kaibuchi, K.5    Kuroda, S.6    Ui, M.7    Iba, H.8    Konishi, H.9    Kikkawa, U.10    Nagata, S.11    Fukui, Y.12
  • 13
    • 0029896163 scopus 로고    scopus 로고
    • Regulation, substrates and functions of src
    • M.T. Brown, and J.A. Cooper Regulation, substrates and functions of src Biochim. Biophys. Acta 1287 1996 121 149
    • (1996) Biochim. Biophys. Acta , vol.1287 , pp. 121-149
    • Brown, M.T.1    Cooper, J.A.2
  • 14
    • 0028958025 scopus 로고
    • Src family protein tyrosine kinases and cellular signal transduction pathways
    • T. Erpel, and S.A. Courtneidge Src family protein tyrosine kinases and cellular signal transduction pathways Curr. Opin. Cell Biol. 7 1995 176 182
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 176-182
    • Erpel, T.1    Courtneidge, S.A.2
  • 15
    • 0026355723 scopus 로고
    • CSK: A protein-tyrosine kinase involved in regulation of src family kinases
    • M. Okada, S. Nada, Y. Yamanashi, T. Yamamoto, and H. Nakagawa CSK: a protein-tyrosine kinase involved in regulation of src family kinases J. Biol. Chem. 266 1991 24249 24252
    • (1991) J. Biol. Chem. , vol.266 , pp. 24249-24252
    • Okada, M.1    Nada, S.2    Yamanashi, Y.3    Yamamoto, T.4    Nakagawa, H.5
  • 16
    • 0025881470 scopus 로고
    • Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
    • S. Nada, M. Okada, A. MacAuley, J.A. Cooper, and H. Nakagawa Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src Nature 351 1991 69 72
    • (1991) Nature , vol.351 , pp. 69-72
    • Nada, S.1    Okada, M.2    MacAuley, A.3    Cooper, J.A.4    Nakagawa, H.5
  • 17
    • 0343878232 scopus 로고    scopus 로고
    • Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development
    • B.W. Howell, T.M. Herrick, J.D. Hildebrand, Y. Zhang, and J.A. Cooper Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development Curr. Biol. 10 2000 877 885
    • (2000) Curr. Biol. , vol.10 , pp. 877-885
    • Howell, B.W.1    Herrick, T.M.2    Hildebrand, J.D.3    Zhang, Y.4    Cooper, J.A.5
  • 18
    • 0035844278 scopus 로고    scopus 로고
    • Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1
    • L. Keshvara, D. Benhayon, S. Magdaleno, and T. Curran Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1 J. Biol. Chem. 276 2001 16008 16014
    • (2001) J. Biol. Chem. , vol.276 , pp. 16008-16014
    • Keshvara, L.1    Benhayon, D.2    Magdaleno, S.3    Curran, T.4
  • 19
    • 0037425580 scopus 로고    scopus 로고
    • Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development
    • L. Arnaud, B.A. Ballif, E. Forster, and J.A. Cooper Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development Curr. Biol. 13 2003 9 17
    • (2003) Curr. Biol. , vol.13 , pp. 9-17
    • Arnaud, L.1    Ballif, B.A.2    Forster, E.3    Cooper, J.A.4
  • 20
    • 0025931499 scopus 로고
    • Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions
    • N.E. Kremer, G. D'Arcangelo, S.M. Thomas, M. DeMarco, J.S. Brugge, and S. Halegoua Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions J. Cell Biol. 115 1991 809 819
    • (1991) J. Cell Biol. , vol.115 , pp. 809-819
    • Kremer, N.E.1    D'Arcangelo, G.2    Thomas, S.M.3    Demarco, M.4    Brugge, J.S.5    Halegoua, S.6
  • 22
    • 0344505849 scopus 로고    scopus 로고
    • Tau interacts with src-family non-receptor tyrosine kinases
    • G. Lee, S.T. Newman, D.L. Gard, H. Band, and G. Panchamoorthy Tau interacts with src-family non-receptor tyrosine kinases J. Cell Sci. 111 Pt. 21 1998 3167 3177
    • (1998) J. Cell Sci. , vol.111 , Issue.PART 21 , pp. 3167-3177
    • Lee, G.1    Newman, S.T.2    Gard, D.L.3    Band, H.4    Panchamoorthy, G.5
  • 23
    • 0027282015 scopus 로고
    • Expression of alternatively spliced src messenger RNAs related to neuronal differentiation in human neuroblastomas
    • T. Matsunaga, H. Shirasawa, M. Tanabe, N. Ohnuma, H. Takahashi, and B. Simizu Expression of alternatively spliced src messenger RNAs related to neuronal differentiation in human neuroblastomas Cancer Res. 53 1993 3179 3185
    • (1993) Cancer Res. , vol.53 , pp. 3179-3185
    • Matsunaga, T.1    Shirasawa, H.2    Tanabe, M.3    Ohnuma, N.4    Takahashi, H.5    Simizu, B.6
  • 24
    • 0023487246 scopus 로고
    • Expression of c-src in cultured human neuroblastoma and small-cell lung carcinoma cell lines correlates with neurocrine differentiation
    • K. Mellstrom, C. Bjelfman, U. Hammerling, and S. Pahlman Expression of c-src in cultured human neuroblastoma and small-cell lung carcinoma cell lines correlates with neurocrine differentiation Mol. Cell. Biol. 7 1987 4178 4184
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4178-4184
    • Mellstrom, K.1    Bjelfman, C.2    Hammerling, U.3    Pahlman, S.4
  • 25
    • 0022372469 scopus 로고
    • Neurones express high levels of a structurally modified, activated form of pp60c-src
    • J.S. Brugge, P.C. Cotton, A.E. Queral, J.N. Barrett, D. Nonner, and R.W. Keane Neurones express high levels of a structurally modified, activated form of pp60c-src Nature 316 1985 554 557
    • (1985) Nature , vol.316 , pp. 554-557
    • Brugge, J.S.1    Cotton, P.C.2    Queral, A.E.3    Barrett, J.N.4    Nonner, D.5    Keane, R.W.6
  • 26
    • 0022559078 scopus 로고
    • Tyr527 is phosphorylated in pp60c-src: Implications for regulation
    • J.A. Cooper, K.L. Gould, C.A. Cartwright, and T. Hunter Tyr527 is phosphorylated in pp60c-src: implications for regulation Science 231 1986 1431 1434
    • (1986) Science , vol.231 , pp. 1431-1434
    • Cooper, J.A.1    Gould, K.L.2    Cartwright, C.A.3    Hunter, T.4
  • 27
    • 0031452274 scopus 로고    scopus 로고
    • Structures of Src-family tyrosine kinases
    • F. Sicheri, and J. Kuriyan Structures of Src-family tyrosine kinases Curr. Opin. Struct. Biol. 7 1997 777 785
    • (1997) Curr. Opin. Struct. Biol. , vol.7 , pp. 777-785
    • Sicheri, F.1    Kuriyan, J.2
  • 28
    • 0032077432 scopus 로고    scopus 로고
    • Insights into Src kinase functions: Structural comparisons
    • J.C. Williams, R.K. Wierenga, and M. Saraste Insights into Src kinase functions: structural comparisons Trends Biochem. Sci. 23 1998 179 184
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 179-184
    • Williams, J.C.1    Wierenga, R.K.2    Saraste, M.3
  • 29
    • 0028059879 scopus 로고
    • Csk suppression of Src involves movement of Csk to sites of Src activity
    • B.W. Howell, and J.A. Cooper Csk suppression of Src involves movement of Csk to sites of Src activity Mol. Cell. Biol. 14 1994 5402 5411
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5402-5411
    • Howell, B.W.1    Cooper, J.A.2
  • 30
    • 0033593220 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK
    • Y. Takayama, S. Tanaka, K. Nagai, and M. Okada Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK J. Biol. Chem. 274 1999 2291 2297
    • (1999) J. Biol. Chem. , vol.274 , pp. 2291-2297
    • Takayama, Y.1    Tanaka, S.2    Nagai, K.3    Okada, M.4
  • 31
    • 0022397461 scopus 로고
    • Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene
    • S. Alema, P. Casalbore, E. Agostini, and F. Tato Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene Nature 316 1985 557 559
    • (1985) Nature , vol.316 , pp. 557-559
    • Alema, S.1    Casalbore, P.2    Agostini, E.3    Tato, F.4
  • 32
    • 0029937918 scopus 로고    scopus 로고
    • Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells [published erratum appears in J Neurosci Res 1996 Oct 1;46(1):129]
    • Z.F. Altun-Gultekin, and J.A. Wagner Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells [published erratum appears in J Neurosci Res 1996 Oct 1;46(1):129] J. Neurosci. Res. 44 1996 308 327
    • (1996) J. Neurosci. Res. , vol.44 , pp. 308-327
    • Altun-Gultekin, Z.F.1    Wagner, J.A.2
  • 33
    • 0027080147 scopus 로고
    • The Src family of tyrosine protein kinases in hemopoietic signal transduction
    • J.B. Bolen, R.B. Rowley, C. Spana, and A.Y. Tsygankov The Src family of tyrosine protein kinases in hemopoietic signal transduction FASEB J. 6 1992 3403 3409
    • (1992) FASEB J. , vol.6 , pp. 3403-3409
    • Bolen, J.B.1    Rowley, R.B.2    Spana, C.3    Tsygankov, A.Y.4
  • 34
    • 0028884113 scopus 로고
    • Structure and developmental regulation of the murine ctk gene
    • P.M. Brinkley, K. Class, J.B. Bolen, and R.C. Penhallow Structure and developmental regulation of the murine ctk gene Gene 163 1995 179 184
    • (1995) Gene , vol.163 , pp. 179-184
    • Brinkley, P.M.1    Class, K.2    Bolen, J.B.3    Penhallow, R.C.4
  • 35
    • 0027971705 scopus 로고
    • NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice
    • H.E. Beggs, P. Soriano, and P.F. Maness NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice J. Cell Biol. 127 1994 825 833
    • (1994) J. Cell Biol. , vol.127 , pp. 825-833
    • Beggs, H.E.1    Soriano, P.2    Maness, P.F.3
  • 36
    • 0026578026 scopus 로고
    • Growth factor signaling: Where is the specificity?
    • M.V. Chao Growth factor signaling: where is the specificity? Cell 68 1992 995 997
    • (1992) Cell , vol.68 , pp. 995-997
    • Chao, M.V.1
  • 37
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • C.J. Marshall Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation Cell 80 1995 179 185
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 38
    • 0029041884 scopus 로고
    • Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation
    • R.R. Vaillancourt, L.E. Heasley, J. Zamarripa, B. Storey, M. Valius, A. Kazlauskas, and G.L. Johnson Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation Mol. Cell. Biol. 15 1995 3644 3653
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3644-3653
    • Vaillancourt, R.R.1    Heasley, L.E.2    Zamarripa, J.3    Storey, B.4    Valius, M.5    Kazlauskas, A.6    Johnson, G.L.7
  • 39
    • 0037124033 scopus 로고    scopus 로고
    • C-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation
    • L.T. Yang, K. Alexandropoulos, and J. Sap c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation J. Biol. Chem. 277 2002 17406 17414
    • (2002) J. Biol. Chem. , vol.277 , pp. 17406-17414
    • Yang, L.T.1    Alexandropoulos, K.2    Sap, J.3
  • 40
    • 0035150732 scopus 로고    scopus 로고
    • Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells
    • O.S. Bang, E.K. Park, S.I. Yang, S.R. Lee, T.F. Franke, and S.S. Kang Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells J. Cell Sci. 114 2001 81 88
    • (2001) J. Cell Sci. , vol.114 , pp. 81-88
    • Bang, O.S.1    Park, E.K.2    Yang, S.I.3    Lee, S.R.4    Franke, T.F.5    Kang, S.S.6
  • 41
    • 0034214218 scopus 로고    scopus 로고
    • A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis
    • R.S. Schmid, W.M. Pruitt, and P.F. Maness A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis J. Neurosci. 20 2000 4177 4188
    • (2000) J. Neurosci. , vol.20 , pp. 4177-4188
    • Schmid, R.S.1    Pruitt, W.M.2    Maness, P.F.3
  • 43
    • 0037205044 scopus 로고    scopus 로고
    • Signaling pathways for PC12 cell differentiation: Making the right connections
    • D. Vaudry, P.J. Stork, P. Lazarovici, and L.E. Eiden Signaling pathways for PC12 cell differentiation: making the right connections Science 296 2002 1648 1649
    • (2002) Science , vol.296 , pp. 1648-1649
    • Vaudry, D.1    Stork, P.J.2    Lazarovici, P.3    Eiden, L.E.4
  • 45
    • 0032820782 scopus 로고    scopus 로고
    • Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
    • D.J. Sieg, C.R. Hauck, and D.D. Schlaepfer Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration J. Cell Sci. 112 1999 2677 2691
    • (1999) J. Cell Sci. , vol.112 , pp. 2677-2691
    • Sieg, D.J.1    Hauck, C.R.2    Schlaepfer, D.D.3
  • 46
    • 0032531732 scopus 로고    scopus 로고
    • Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
    • D.J. Sieg, D. Ilic, K.C. Jones, C.H. Damsky, T. Hunter, and D.D. Schlaepfer Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration EMBO J. 17 1998 5933 5947
    • (1998) EMBO J. , vol.17 , pp. 5933-5947
    • Sieg, D.J.1    Ilic, D.2    Jones, K.C.3    Damsky, C.H.4    Hunter, T.5    Schlaepfer, D.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.