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Volumn 69, Issue 9, 2006, Pages 793-809

The role of death receptor signaling in testicular germ-cell apoptosis triggered by mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell injury and its implications for risk assessment

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR; FAS ANTIBODY; FAS ANTIGEN; FAS LIGAND; FLICE INHIBITORY PROTEIN; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PROTEIN P53; TUMOR NECROSIS FACTOR;

EID: 33646478410     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390600591447     Document Type: Conference Paper
Times cited : (2)

References (99)
  • 1
    • 0027477302 scopus 로고
    • Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice
    • Adachi, M., Watanabe-Fukunaga, R., and Nagata, S. 1993. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl. Acad. Sci. USA 90:1756-1760.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1756-1760
    • Adachi, M.1    Watanabe-Fukunaga, R.2    Nagata, S.3
  • 2
    • 0035369143 scopus 로고    scopus 로고
    • The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
    • Adrain, C., and Martin, S. J. 2001. The mitochondrial apoptosome: A killer unleashed by the cytochrome seas. Trends Biochem. Sci. 26:390-397.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 390-397
    • Adrain, C.1    Martin, S.J.2
  • 3
    • 0002353510 scopus 로고
    • The biochemical toxicology of di-(2-ethylhexyl) and related phthalates: Testicular atrophy and hepatocarcinogenesis
    • Albro, P. W. 1987. The biochemical toxicology of di-(2-ethylhexyl) and related phthalates: Testicular atrophy and hepatocarcinogenesis. Rev. Biochem. Toxicol. 8:73-119.
    • (1987) Rev. Biochem. Toxicol. , vol.8 , pp. 73-119
    • Albro, P.W.1
  • 4
    • 0021377179 scopus 로고
    • Determination of total phthalate in urine by gas chromatography
    • Albro, P. W., Jordan, S., Corbett, J. T., and Schroeder, J. L. 1984. Determination of total phthalate in urine by gas chromatography. Anal. Chem. 56:247-250.
    • (1984) Anal. Chem. , vol.56 , pp. 247-250
    • Albro, P.W.1    Jordan, S.2    Corbett, J.T.3    Schroeder, J.L.4
  • 5
    • 0026709129 scopus 로고
    • Spermatogonial apoptosis has three morphologically recognizable phases and shows no circadian rhythm during normal spermatogenesis in the rat
    • Allan, D. J., Harnon, B. V., and Roberts, S. A. 1992. Spermatogonial apoptosis has three morphologically recognizable phases and shows no circadian rhythm during normal spermatogenesis in the rat. Cell Prolif. 25:241-250.
    • (1992) Cell Prolif. , vol.25 , pp. 241-250
    • Allan, D.J.1    Harnon, B.V.2    Roberts, S.A.3
  • 6
    • 16544381894 scopus 로고    scopus 로고
    • An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro
    • Andriana, B. B., Tay, T. W., Maki, I., Awal, M. A., Kanai, Y., Kurohmaru, M., and Hayashi, Y. 2004. An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro. J. Vet. Sci. 5:235-240.
    • (2004) J. Vet. Sci. , vol.5 , pp. 235-240
    • Andriana, B.B.1    Tay, T.W.2    Maki, I.3    Awal, M.A.4    Kanai, Y.5    Kurohmaru, M.6    Hayashi, Y.7
  • 7
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A., and Dixit, V. M. 1998. Death receptors: Signaling and modulation. Science 281:1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 9
    • 11244275678 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate (MEHP) induces spermatogenic cell apoptosis in guinea pig testes at prepubertal stage in vitro
    • Awal, M. A., Kurohmaru, M., Ishii, M., Andriana, B. B., Kanai, Y., and Hayashi, Y. 2004. Mono-(2-ethylhexyl) phthalate (MEHP) induces spermatogenic cell apoptosis in guinea pig testes at prepubertal stage in vitro. Int. J. Toxicol. 23:349-355.
    • (2004) Int. J. Toxicol. , vol.23 , pp. 349-355
    • Awal, M.A.1    Kurohmaru, M.2    Ishii, M.3    Andriana, B.B.4    Kanai, Y.5    Hayashi, Y.6
  • 10
    • 0037772270 scopus 로고    scopus 로고
    • Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to di(n-butyl) phthalate
    • Barlow, N. J., and Foster, P. M. 2003. Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to di(n-butyl) phthalate. Toxicol. Pathol. 31:397-410
    • (2003) Toxicol. Pathol. , vol.31 , pp. 397-410
    • Barlow, N.J.1    Foster, P.M.2
  • 12
    • 0029926356 scopus 로고    scopus 로고
    • Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: Re-evaluation of cell types that exhibit the ability to die during spermatogenesis
    • Blanco-Rodriguez, J., and Martinez-Garcia, C. 1996. Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: Re-evaluation of cell types that exhibit the ability to die during spermatogenesis. Cell Prolif. 29:13-31.
    • (1996) Cell Prolif. , vol.29 , pp. 13-31
    • Blanco-Rodriguez, J.1    Martinez-Garcia, C.2
  • 13
    • 0031462531 scopus 로고    scopus 로고
    • In vivo analysis of germ cell apoptosis reveals the existence of stage-specific "social" control of germ cell death in the seminiferous epithelium
    • Blanco-Rodriguez, J., and Martinez-Garcia, C. 1997. In vivo analysis of germ cell apoptosis reveals the existence of stage-specific "social" control of germ cell death in the seminiferous epithelium. Int. J. Androl. 20:373-379.
    • (1997) Int. J. Androl. , vol.20 , pp. 373-379
    • Blanco-Rodriguez, J.1    Martinez-Garcia, C.2
  • 14
    • 0032435386 scopus 로고    scopus 로고
    • Expression of Fas system-related genes in the testis during development and after toxicant exposure
    • Boekelheide, K., Lee, J., Shipp, E. B., Richburg, J. H., and Li, G. 1998. Expression of Fas system-related genes in the testis during development and after toxicant exposure. Toxicol. Lett. 102-103:503-508.
    • (1998) Toxicol. Lett. , vol.102-103 , pp. 503-508
    • Boekelheide, K.1    Lee, J.2    Shipp, E.B.3    Richburg, J.H.4    Li, G.5
  • 15
    • 84884734103 scopus 로고    scopus 로고
    • Sertoli cell toxicants
    • eds. M. K. Skinner and M. D. Griswold, San Diego: Elsevier
    • Boekelheide, K., Johnson, K. K., and Richburg, J. H. 2005. Sertoli cell toxicants. In Sertoli cell biology, eds. M. K. Skinner and M. D. Griswold, pp. 345-382. San Diego: Elsevier.
    • (2005) Sertoli Cell Biology , pp. 345-382
    • Boekelheide, K.1    Johnson, K.K.2    Richburg, J.H.3
  • 16
    • 0034630330 scopus 로고    scopus 로고
    • Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis
    • Bratton, S. B., MacFarlane, M., Cain, K., and Cohen, G. M. 2000. Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Exp. Cell Res. 256:27-33.
    • (2000) Exp. Cell Res. , vol.256 , pp. 27-33
    • Bratton, S.B.1    MacFarlane, M.2    Cain, K.3    Cohen, G.M.4
  • 17
    • 0035283038 scopus 로고    scopus 로고
    • Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes
    • Bratton, S. B., Walker, G., Srinivasula, S. M., Sun, X. M., Butterworth, M., Alnemri, E. S., and Cohen, G. M. 2001. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J. 20:998-1009.
    • (2001) EMBO J. , vol.20 , pp. 998-1009
    • Bratton, S.B.1    Walker, G.2    Srinivasula, S.M.3    Sun, X.M.4    Butterworth, M.5    Alnemri, E.S.6    Cohen, G.M.7
  • 18
    • 10944232852 scopus 로고    scopus 로고
    • The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP
    • Chandrasekaran, Y., and Richburg, J. H. 2005. The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP. Biol. Reprod. 72:206-213.
    • (2005) Biol. Reprod. , vol.72 , pp. 206-213
    • Chandrasekaran, Y.1    Richburg, J.H.2
  • 19
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan, A. M., O'Rourke, K., Tewari, M., and Dixit, V. M. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 20
    • 0023183306 scopus 로고
    • The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat
    • Creasy, D. M., Beech, L. M., Gray, T. J. B., and Butler, W. H. 1987. The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat. Exp. Mol. Pathol. 46:357-371.
    • (1987) Exp. Mol. Pathol. , vol.46 , pp. 357-371
    • Creasy, D.M.1    Beech, L.M.2    Gray, T.J.B.3    Butler, W.H.4
  • 23
    • 0035978461 scopus 로고    scopus 로고
    • The acute effects of mono(2-ethylhexyl)phthalate (MEHP) on testes of prepubertal Wistar rats
    • Dalgaard, M., Nellemann, C., Lam, H. R., Sorensen, I. K., and Ladefoged, O. 2001. The acute effects of mono(2-ethylhexyl)phthalate (MEHP) on testes of prepubertal Wistar rats. Toxicol. Lett. 122:69-79.
    • (2001) Toxicol. Lett. , vol.122 , pp. 69-79
    • Dalgaard, M.1    Nellemann, C.2    Lam, H.R.3    Sorensen, I.K.4    Ladefoged, O.5
  • 24
    • 0029005672 scopus 로고
    • Neonatal hypothyroidism causes delayed Sertoli cell maturation in rats treated with propylthiouracil: Evidence that the Sertoli cell controls testis growth
    • De Franca, L. R., Hess, R. A., Cooke, P. S., and Russell, L. D. 1995. Neonatal hypothyroidism causes delayed Sertoli cell maturation in rats treated with propylthiouracil: Evidence that the Sertoli cell controls testis growth. Anat. Rec. 242:57-69.
    • (1995) Anat. Rec. , vol.242 , pp. 57-69
    • De Franca, L.R.1    Hess, R.A.2    Cooke, P.S.3    Russell, L.D.4
  • 26
    • 0030915178 scopus 로고    scopus 로고
    • Clinical aspects of male germ cell apoptosis during testis development and spermatogenesis
    • Dunkel, L., Hirvonen, V., and Erkkilä, K. 1997. Clinical aspects of male germ cell apoptosis during testis development and spermatogenesis. Cell Death Differ. 4:171-179.
    • (1997) Cell Death Differ. , vol.4 , pp. 171-179
    • Dunkel, L.1    Hirvonen, V.2    Erkkilä, K.3
  • 27
    • 0036517825 scopus 로고    scopus 로고
    • Fas-Fas ligand system as a possible mediator of spermatogenic cell apoptosis in human maturation-arrested testes
    • Eguchi, J., Koji, T., Nomata, K., Yoshii, A., Shin, M., and Kanetake, H. 2002. Fas-Fas ligand system as a possible mediator of spermatogenic cell apoptosis in human maturation-arrested testes. Hum. Cell 15:61-68.
    • (2002) Hum. Cell , vol.15 , pp. 61-68
    • Eguchi, J.1    Koji, T.2    Nomata, K.3    Yoshii, A.4    Shin, M.5    Kanetake, H.6
  • 28
    • 0036268720 scopus 로고    scopus 로고
    • Involvement of Fas system and active caspases in apoptotic signaling in testicular germ cells of ethanol-treated rats
    • Eid, N. A., Shibata, M. A., Ito, Y., Kusakabe, K., Hammad, H., and Otsuki, Y. 2002. Involvement of Fas system and active caspases in apoptotic signaling in testicular germ cells of ethanol-treated rats. Int. J. Androl. 25:159-167.
    • (2002) Int. J. Androl. , vol.25 , pp. 159-167
    • Eid, N.A.1    Shibata, M.A.2    Ito, Y.3    Kusakabe, K.4    Hammad, H.5    Otsuki, Y.6
  • 29
    • 0038575340 scopus 로고    scopus 로고
    • Human "testicular dysgenesis syndrome": A possible model using in utero exposure of the rat to dibutyl phthalate
    • Fisher, J. S., Macpherson, S., Marchetti, N., and Sharpe, R. M. 2003. Human "testicular dysgenesis syndrome": A possible model using in utero exposure of the rat to dibutyl phthalate. Hum. Reprod. 18:1383-1394.
    • (2003) Hum. Reprod. , vol.18 , pp. 1383-1394
    • Fisher, J.S.1    Macpherson, S.2    Marchetti, N.3    Sharpe, R.M.4
  • 31
    • 0029985912 scopus 로고    scopus 로고
    • Fas and Fas ligand in embryos and adult mice: Ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover
    • French, L. E., Hahne, M., Viard, I., Radlgruber, G., Zanone, R., Becker, K., Muller, C., and Tschopp, J. 1996. Fas and Fas ligand in embryos and adult mice: Ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J. Cell. Biol. 133:335-343.
    • (1996) J. Cell. Biol. , vol.133 , pp. 335-343
    • French, L.E.1    Hahne, M.2    Viard, I.3    Radlgruber, G.4    Zanone, R.5    Becker, K.6    Muller, C.7    Tschopp, J.8
  • 32
  • 33
    • 0036941914 scopus 로고    scopus 로고
    • Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure
    • Giammona, C. J., Sawhney, P., Chandrasekaran, Y., and Richburg, J. H. 2002. Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure. Toxicol. Appl. Pharmacol. 185:119-127.
    • (2002) Toxicol. Appl. Pharmacol. , vol.185 , pp. 119-127
    • Giammona, C.J.1    Sawhney, P.2    Chandrasekaran, Y.3    Richburg, J.H.4
  • 35
    • 0032322272 scopus 로고    scopus 로고
    • Increased apoptosis in the contralateral testes of patients with testicular torsion as a factor for infertility
    • Hadziselimovic, F., Geneto, R., and Emmons, L. R. 1998. Increased apoptosis in the contralateral testes of patients with testicular torsion as a factor for infertility. J. Urol. 160:1158-1160.
    • (1998) J. Urol. , vol.160 , pp. 1158-1160
    • Hadziselimovic, F.1    Geneto, R.2    Emmons, L.R.3
  • 38
    • 0242543287 scopus 로고    scopus 로고
    • Co-localized expression of FasL, Fas, caspase-3 and apoptotic DNA fragmentation in mouse testis after oral exposure to di(2-ethylhexyl)phthalate
    • Ichimura, T., Kawamura, M., and Mitani, A. 2003. Co-localized expression of FasL, Fas, caspase-3 and apoptotic DNA fragmentation in mouse testis after oral exposure to di(2-ethylhexyl)phthalate. Toxicology 194:35-42.
    • (2003) Toxicology , vol.194 , pp. 35-42
    • Ichimura, T.1    Kawamura, M.2    Mitani, A.3
  • 40
    • 0027140989 scopus 로고
    • Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse
    • Joyce, K. L., Porcelli, J., and Cooke, P. S. 1993. Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse. J. Androl. 14:448-455.
    • (1993) J. Androl. , vol.14 , pp. 448-455
    • Joyce, K.L.1    Porcelli, J.2    Cooke, P.S.3
  • 41
    • 0033534465 scopus 로고    scopus 로고
    • Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappa β
    • Kasibhatla, S., Genestier, L., and Green, D. R. 1999. Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappa β. J. Biol. Chem. 274:987-992.
    • (1999) J. Biol. Chem. , vol.274 , pp. 987-992
    • Kasibhatla, S.1    Genestier, L.2    Green, D.R.3
  • 43
    • 0037274017 scopus 로고    scopus 로고
    • Signaling and transcriptional control of Fas ligand gene expression
    • Kavurma, M. M., and Khachigian, L. M. 2003. Signaling and transcriptional control of Fas ligand gene expression. Cell Death Differ. 10:36-44.
    • (2003) Cell Death Differ. , vol.10 , pp. 36-44
    • Kavurma, M.M.1    Khachigian, L.M.2
  • 44
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J. F., Wyllie, A. H., and Currie, A. R. 1972. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 45
    • 0036207664 scopus 로고    scopus 로고
    • Involvement of the Fas/FasL pathway in the pathogenesis of germ cell tumors of the adult testis
    • Kersemaekers, A. M., van Weeren, P. C., Oosterhuis, J. W., and Looijenga, L. H. 2002. Involvement of the Fas/FasL pathway in the pathogenesis of germ cell tumors of the adult testis. J. Pathol. 196:423-429.
    • (2002) J. Pathol. , vol.196 , pp. 423-429
    • Kersemaekers, A.M.1    Van Weeren, P.C.2    Oosterhuis, J.W.3    Looijenga, L.H.4
  • 46
    • 23844539020 scopus 로고    scopus 로고
    • Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact
    • Kleymenova, E., Swanson, C., Boekelheide, K., and Gaido, K. W. 2005. Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact. Biol. Reprod. 73:482-490.
    • (2005) Biol. Reprod. , vol.73 , pp. 482-490
    • Kleymenova, E.1    Swanson, C.2    Boekelheide, K.3    Gaido, K.W.4
  • 47
    • 0035738232 scopus 로고    scopus 로고
    • Male germ cell death in mouse testes: Possible involvement of Fas and Fas ligand
    • Koji, T. 2001. Male germ cell death in mouse testes: Possible involvement of Fas and Fas ligand. Med. Electron Microsc. 34:213-222.
    • (2001) Med. Electron Microsc. , vol.34 , pp. 213-222
    • Koji, T.1
  • 48
    • 0035115923 scopus 로고    scopus 로고
    • Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: Involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis
    • Koji, T., Hishikawa, Y., Ando, H., Nakanishi, Y., and Kobayashi, N. 2001. Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: Involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis. Biol. Reprod. 64:946-954.
    • (2001) Biol. Reprod. , vol.64 , pp. 946-954
    • Koji, T.1    Hishikawa, Y.2    Ando, H.3    Nakanishi, Y.4    Kobayashi, N.5
  • 49
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates Bid, which oligomerizes Bak or Bax into pores that result in the release of cytochrome c
    • Korsmeyer, S. J., Wei, M. C., Saito, M., Weiler, S., Oh, K. J., and Schlesinger, P. H. 2000. Pro-apoptotic cascade activates Bid, which oligomerizes Bak or Bax into pores that result in the release of cytochrome c. Cell Death Differ. 7:1166-1173.
    • (2000) Cell Death Differ. , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3    Weiler, S.4    Oh, K.J.5    Schlesinger, P.H.6
  • 50
    • 0035192884 scopus 로고    scopus 로고
    • FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
    • Krueger, A., Baumann, S., Krammer, P. H., and Kirchhoff, S. 2001a. FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis. Mol. Cell Biol. 21:8247-8254.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 8247-8254
    • Krueger, A.1    Baumann, S.2    Krammer, P.H.3    Kirchhoff, S.4
  • 51
    • 0035827569 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
    • Krueger, A., Schmitz, I., Baumann, S., Krammer, P. H., and Kirchhoff, S. 2001. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J. Biol. Chem. 276:20633-20640.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20633-20640
    • Krueger, A.1    Schmitz, I.2    Baumann, S.3    Krammer, P.H.4    Kirchhoff, S.5
  • 52
    • 0030890609 scopus 로고    scopus 로고
    • The Fas system is a key regulator of germ cell apoptosis in the testis
    • Lee, J., Richburg, J. H., Younkin, S. C., and Boekelheide, K. 1997. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138:2081-2088.
    • (1997) Endocrinology , vol.138 , pp. 2081-2088
    • Lee, J.1    Richburg, J.H.2    Younkin, S.C.3    Boekelheide, K.4
  • 53
    • 0032910202 scopus 로고    scopus 로고
    • The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis
    • Lee, J., Richburg, J. H., Shipp, E. B., Meistrich, M. L., and Boekelheide, K. 1999. The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis. Endocrinology 140:852-858.
    • (1999) Endocrinology , vol.140 , pp. 852-858
    • Lee, J.1    Richburg, J.H.2    Shipp, E.B.3    Meistrich, M.L.4    Boekelheide, K.5
  • 54
    • 0037334071 scopus 로고    scopus 로고
    • Role of mitochondrial cytochrome c in cocaine-induced apoptosis in rat testes
    • Li, H., Xu, L., Dunbar, J. C., and Dhabuwala, C. B. 2003. Role of mitochondrial cytochrome c in cocaine-induced apoptosis in rat testes. Urology 61:646-650.
    • (2003) Urology , vol.61 , pp. 646-650
    • Li, H.1    Xu, L.2    Dunbar, J.C.3    Dhabuwala, C.B.4
  • 55
    • 0031450241 scopus 로고    scopus 로고
    • In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis
    • Lin, W. W., Lamb, D. J., Wheeler, T. M., Lipshultz, L. I., and Kim, E. D. 1997. In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis. Fertil. Steril. 68:1065-1069.
    • (1997) Fertil. Steril. , vol.68 , pp. 1065-1069
    • Lin, W.W.1    Lamb, D.J.2    Wheeler, T.M.3    Lipshultz, L.I.4    Kim, E.D.5
  • 56
    • 12344267731 scopus 로고    scopus 로고
    • Abnormal Leydig cell aggregation in the fetal testis of rats exposed to di(n-butyl) phthalate and its possible role in testicular dysgenesis
    • Mahood, I. K., Hallmark, N., McKinnell, C., Walker, M., Fisher, J. S., and Sharpe, R. M. 2005. Abnormal Leydig cell aggregation in the fetal testis of rats exposed to di(n-butyl) phthalate and its possible role in testicular dysgenesis. Endocrinology 146:613-623.
    • (2005) Endocrinology , vol.146 , pp. 613-623
    • Mahood, I.K.1    Hallmark, N.2    McKinnell, C.3    Walker, M.4    Fisher, J.S.5    Sharpe, R.M.6
  • 57
    • 0028600059 scopus 로고
    • The apo-1/Fas (cd95) receptor is expressed in homozygous Mrl/lpr mice
    • Mariani, S. M., Matiba, B., Armandola, E. A., and Krammer, P. H. 1994. The apo-1/Fas (cd95) receptor is expressed in homozygous Mrl/lpr mice. Eur. J. Immunol. 24:3119-3123.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3119-3123
    • Mariani, S.M.1    Matiba, B.2    Armandola, E.A.3    Krammer, P.H.4
  • 58
    • 0033583315 scopus 로고    scopus 로고
    • Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1
    • McClure, R. F., Heppelmann, C. J., and Paya, C. V. 1999. Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1. J. Biol. Chem. 274:7756-7762.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7756-7762
    • McClure, R.F.1    Heppelmann, C.J.2    Paya, C.V.3
  • 59
    • 0026597538 scopus 로고
    • Germ-cell death during prespermatogenesis in the testis of the golden hamster
    • Miething, A. 1992. Germ-cell death during prespermatogenesis in the testis of the golden hamster. Cell Tissue Res. 267:583-590.
    • (1992) Cell Tissue Res. , vol.267 , pp. 583-590
    • Miething, A.1
  • 60
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S. 1997. Apoptosis by death factor. Cell 88:355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 61
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S., and Golstein, P. 1995. The Fas death factor. Science 267:1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 62
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • January
    • Nagata, S., and Suda, T. 1995. Fas and Fas ligand: Lpr and gld mutations. Immunol. Today January 16:39-43.
    • (1995) Immunol. Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 63
    • 59849117196 scopus 로고    scopus 로고
    • NTP-CERHR monograph on the potential human reproductive and developmental effects of di-n-butyl phthalate (DBP)
    • National Toxicology Program. 2003. NTP-CERHR monograph on the potential human reproductive and developmental effects of di-n-butyl phthalate (DBP). NTP CERHR Mon. i-III90.
    • (2003) NTP CERHR Mon.
  • 64
    • 0031979568 scopus 로고    scopus 로고
    • Involvement of Fas in the apoptosis of mouse germ cells induced by experimental cryptorchidism
    • Ogi, S., Tanji, N., Yokoyama, M., Takeuchi, M., and Terada, N. 1998. Involvement of Fas in the apoptosis of mouse germ cells induced by experimental cryptorchidism. Urol. Res. 26:17-21.
    • (1998) Urol. Res. , vol.26 , pp. 17-21
    • Ogi, S.1    Tanji, N.2    Yokoyama, M.3    Takeuchi, M.4    Terada, N.5
  • 65
    • 0037186347 scopus 로고    scopus 로고
    • Testicular toxicity of di-(2-ethylhexyl)phthalate in young Sprague-Dawley rats
    • Park, J. D., Habeebu, S. S., and Klaassen, C. D. 2002. Testicular toxicity of di-(2-ethylhexyl)phthalate in young Sprague-Dawley rats. Toxicology 171:105-115.
    • (2002) Toxicology , vol.171 , pp. 105-115
    • Park, J.D.1    Habeebu, S.S.2    Klaassen, C.D.3
  • 66
    • 0033030170 scopus 로고    scopus 로고
    • Fas regulates germ cell apoptosis in the human testis in vitro
    • Pentikäinen, V., Erkkilä, K., and Dunkel, L. 1999. Fas regulates germ cell apoptosis in the human testis in vitro. Am. J. Physiol. 276:E310-E316.
    • (1999) Am. J. Physiol. , vol.276
    • Pentikäinen, V.1    Erkkilä, K.2    Dunkel, L.3
  • 68
    • 0037276437 scopus 로고    scopus 로고
    • The CD95(Apo-1/Fas) disc and beyond
    • Peter, M. E., and Krammer, P. H. 2003. The CD95(Apo-1/Fas) disc and beyond. Cell Death Differ. 10:26-35.
    • (2003) Cell Death Differ. , vol.10 , pp. 26-35
    • Peter, M.E.1    Krammer, P.H.2
  • 69
    • 0034064385 scopus 로고    scopus 로고
    • Germ cell suicide: New insights into apoptosis during spermatogenesis
    • Print, C. G., and Loveland, K. L. 2000. Germ cell suicide: New insights into apoptosis during spermatogenesis. Bioessays 22:423-430.
    • (2000) Bioessays , vol.22 , pp. 423-430
    • Print, C.G.1    Loveland, K.L.2
  • 71
    • 0034654289 scopus 로고    scopus 로고
    • The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology
    • Richburg, J. H. 2000. The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology. Toxicol. Lett. 112-113:79-86.
    • (2000) Toxicol. Lett. , vol.112-113 , pp. 79-86
    • Richburg, J.H.1
  • 72
    • 0029995352 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes
    • Richburg, J. H., and Boekelheide, K. 1996. Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes. Toxicol. Appl. Pharmacol. 137:42-50.
    • (1996) Toxicol. Appl. Pharmacol. , vol.137 , pp. 42-50
    • Richburg, J.H.1    Boekelheide, K.2
  • 73
    • 0345440129 scopus 로고    scopus 로고
    • Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate
    • Richburg, J. H., Nanez, A., and Gao, H. 1999. Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate. Toxicol. Appl. Pharmacol. 160:271-278.
    • (1999) Toxicol. Appl. Pharmacol. , vol.160 , pp. 271-278
    • Richburg, J.H.1    Nanez, A.2    Gao, H.3
  • 74
    • 0034465421 scopus 로고    scopus 로고
    • Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand
    • Richburg, J. H., Nanez, A., Williams, L. R., Embree, M. E., and Boekelheide, K. 2000. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology 141:787-793.
    • (2000) Endocrinology , vol.141 , pp. 787-793
    • Richburg, J.H.1    Nanez, A.2    Williams, L.R.3    Embree, M.E.4    Boekelheide, K.5
  • 76
    • 0000100846 scopus 로고
    • Acute and subacute toxicity of di(2-ethylhexyl) phthalate with note upon its metabolism
    • Schaffer, C. B., Carpenter, C. P., and Smyth, H. F., Jr. 1945. Acute and subacute toxicity of di(2-ethylhexyl) phthalate with note upon its metabolism. J. Ind. Hyg. Toxicol. 27:130-135.
    • (1945) J. Ind. Hyg. Toxicol. , vol.27 , pp. 130-135
    • Schaffer, C.B.1    Carpenter, C.P.2    Smyth Jr., H.F.3
  • 77
    • 0029030962 scopus 로고
    • Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment
    • Sinha Hikim, A. P., Wang, C., Leung, A., and Swerdloff, R. S. 1995. Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment. Endocrinology 136:2770-2775.
    • (1995) Endocrinology , vol.136 , pp. 2770-2775
    • Sinha Hikim, A.P.1    Wang, C.2    Leung, A.3    Swerdloff, R.S.4
  • 79
    • 0022500653 scopus 로고
    • Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro
    • Sjoberg, P., Bondesson, U., Gray, T. J., and Ploen, L. 1986. Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro. Acta Pharmacol Toxicol (copenh) 58:225-233.
    • (1986) Acta Pharmacol Toxicol (Copenh) , vol.58 , pp. 225-233
    • Sjoberg, P.1    Bondesson, U.2    Gray, T.J.3    Ploen, L.4
  • 81
    • 15744374877 scopus 로고    scopus 로고
    • The mouse cell surface protein TOSO regulates Fas/Fas-ligand induced apoptosis through its binding to Fas-associated death domain
    • Song, Y., and Jacob, C. O. 2005. The mouse cell surface protein TOSO regulates Fas/Fas-ligand induced apoptosis through its binding to Fas-associated death domain. J. Biol. Chem. 280: 9618-9626.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9618-9626
    • Song, Y.1    Jacob, C.O.2
  • 82
    • 0037531809 scopus 로고    scopus 로고
    • The attractive achilles heel of germ cell tumours: An inherent sensitivity to apoptosis-inducing stimuli
    • Spierings, D. C., de Vries, E. G., Vellenga, E., and de Jong, S. 2003. The attractive achilles heel of germ cell tumours: An inherent sensitivity to apoptosis-inducing stimuli. J. Pathol. 200:137-148.
    • (2003) J. Pathol. , vol.200 , pp. 137-148
    • Spierings, D.C.1    De Vries, E.G.2    Vellenga, E.3    De Jong, S.4
  • 85
    • 0031467487 scopus 로고    scopus 로고
    • Expression of Fas and Fas ligand in the testes and testicular germ cell tumors: An immunohistochemical study
    • Sugihara, A., Saiki, S., Tsuji, M., Tsujimura, T., Nakata, Y., Kubota, A., Kotake, T., and Terada, N. 1997. Expression of Fas and Fas ligand in the testes and testicular germ cell tumors: An immunohistochemical study. Anticancer Res. 17:3861-3865.
    • (1997) Anticancer Res. , vol.17 , pp. 3861-3865
    • Sugihara, A.1    Saiki, S.2    Tsuji, M.3    Tsujimura, T.4    Nakata, Y.5    Kubota, A.6    Kotake, T.7    Terada, N.8
  • 87
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand
    • Takahashi, T., Tanaka, M., Brannan, C. I., Jenkins, N. A., Copeland, N. G., Suda, T., and Nagata, S. 1994. Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 76:969-977.
    • (1994) Cell , vol.76 , pp. 969-977
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 88
    • 0021603008 scopus 로고
    • Biological effects of di-(2-ethylhexyl) phthalate and other phthalic acid esters
    • Thomas, J. A., and Thomas, M. J. 1984. Biological effects of di-(2-ethylhexyl) phthalate and other phthalic acid esters. Crit. Rev. Toxicol. 13:283-317.
    • (1984) Crit. Rev. Toxicol. , vol.13 , pp. 283-317
    • Thomas, J.A.1    Thomas, M.J.2
  • 89
    • 0017603783 scopus 로고
    • Phthalic acid esters in various foodstuffs and biological materials
    • Tomita, I., Nakamura, Y., and Yagi, Y. 1977. Phthalic acid esters in various foodstuffs and biological materials. Ecotoxicol. Environ. Safety 1:275-287.
    • (1977) Ecotoxicol. Environ. Safety , vol.1 , pp. 275-287
    • Tomita, I.1    Nakamura, Y.2    Yagi, Y.3
  • 91
    • 1942508663 scopus 로고    scopus 로고
    • Mitochondria-dependent pathway is involved in heat-induced male germ cell death: Lessons from mutant mice
    • Vera, Y., Diaz-Romero, M., Rodriguez, S., Lue, Y., Wang, C., Swerdloff, R. S., and Sinha Hikim, A. P. 2004. Mitochondria-dependent pathway is involved in heat-induced male germ cell death: Lessons from mutant mice. Biol. Reprod. 70:1534-1540.
    • (2004) Biol. Reprod. , vol.70 , pp. 1534-1540
    • Vera, Y.1    Diaz-Romero, M.2    Rodriguez, S.3    Lue, Y.4    Wang, C.5    Swerdloff, R.S.6    Sinha Hikim, A.P.7
  • 92
    • 0031978777 scopus 로고    scopus 로고
    • Autonomous cell death of mouse male germ cells during fetal and postnatal period
    • Wang, R. A., Nakane, P. K., and Koji, T. 1998. Autonomous cell death of mouse male germ cells during fetal and postnatal period. Biol. Reprod. 58:1250-1256.
    • (1998) Biol. Reprod. , vol.58 , pp. 1250-1256
    • Wang, R.A.1    Nakane, P.K.2    Koji, T.3
  • 94
    • 0027245048 scopus 로고
    • Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene
    • Wu, J., Zhou, T., He, J., and Mountz, J. D. 1993. Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene. J. Exp. Med. 178:461-468.
    • (1993) J. Exp. Med. , vol.178 , pp. 461-468
    • Wu, J.1    Zhou, T.2    He, J.3    Mountz, J.D.4
  • 95
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie, A. H., Kerr, J. F. R., and Curie, A. R. 1980. Cell death: The significance of apoptosis. Int. Rev. Cytol. 68:251-306.
    • (1980) Int. Rev. Cytol. , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.R.2    Curie, A.R.3
  • 96
    • 0035179975 scopus 로고    scopus 로고
    • Sp1 is the major FasL gene activator in abnormal CD4(-)CD8(-)B220(+) T cells of lpr and gld mice
    • Xiao, S., Marshak-Rothstein, A., and Ju, S. T. 2001. Sp1 is the major FasL gene activator in abnormal CD4(-)CD8(-)B220(+) T cells of lpr and gld mice. Eur. J. Immunol. 31:3339-3348.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3339-3348
    • Xiao, S.1    Marshak-Rothstein, A.2    Ju, S.T.3
  • 98
    • 0033596980 scopus 로고    scopus 로고
    • An Apaf-1.Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou, H., Li, Y., Liu, X., and Wang, X. 1999. An Apaf-1.Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274:11549-11556.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4


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