메뉴 건너뛰기




Volumn 194, Issue 1-2, 2003, Pages 35-42

Co-localized expression of FasL, Fas, Caspase-3 and apoptotic DNA fragmentation in mouse testis after oral exposure to di(2-ethylhexyl)phthalate

Author keywords

Apoptosis; Di(2 ethylhexyl)phthalate; Fas; Testis; TUNEL

Indexed keywords

CASPASE 3; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; FAS ANTIGEN; FAS LIGAND; FLUORESCEIN; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

EID: 0242543287     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2003.07.003     Document Type: Article
Times cited : (39)

References (24)
  • 1
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protenase in Fas-mediated apoptosis
    • Adachi M., Watanabe-Fukunaga R., Nagata S. Involvement of an ICE-like protenase in Fas-mediated apoptosis. Nature. 375:1995;78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Adachi, M.1    Watanabe-Fukunaga, R.2    Nagata, S.3
  • 2
    • 0024417512 scopus 로고
    • Mono-2-ethylhexyl phthalate, a metabolite of di-(2-ethylhexyl) phthalate, causally linked to testicular atrophy in rats
    • Albro P.W., Chapin I.L.E., Corbett J.T., Schroeder J., Phelps J.Li. Mono-2-ethylhexyl phthalate, a metabolite of di-(2-ethylhexyl) phthalate, causally linked to testicular atrophy in rats. Toxicol. Appl. Pharmacol. 100(2):1989;193-200.
    • (1989) Toxicol. Appl. Pharmacol. , vol.100 , Issue.2 , pp. 193-200
    • Albro, P.W.1    Chapin, I.L.E.2    Corbett, J.T.3    Schroeder, J.4    Phelps, J.Li.5
  • 3
    • 0032435386 scopus 로고    scopus 로고
    • Expression of Fas system-related genes in the testis during development and after toxicant exposure
    • Boekelheide, K., Lee, J., Shipp, E.B., Richburg, J.H., Li, G., 1998. Expression of Fas system-related genes in the testis during development and after toxicant exposure, Toxicol. Lett. 102-103.
    • (1998) Toxicol. Lett. , pp. 102-103
    • Boekelheide, K.1    Lee, J.2    Shipp, E.B.3    Richburg, J.H.4    Li, G.5
  • 4
    • 0035978461 scopus 로고    scopus 로고
    • The acute effects of mono (2-ethylhexyl) phthalate (MEHP) on testis of prepubertal Wister rats
    • Dalgaard M., Nellemann C., Lam H.I.L., Sorensen I.K., Ladefoged O. The acute effects of mono (2-ethylhexyl) phthalate (MEHP) on testis of prepubertal Wister rats. Toxicol. Lett. 122(1):2001;69-79.
    • (2001) Toxicol. Lett. , vol.122 , Issue.1 , pp. 69-79
    • Dalgaard, M.1    Nellemann, C.2    Lam, H.I.L.3    Sorensen, I.K.4    Ladefoged, O.5
  • 5
    • 0034044372 scopus 로고    scopus 로고
    • Chronic toxidty of di (2-ethylhexyl) phthalate in rats
    • David R.M., Moore M.R., Finney D.C., Guest D. Chronic toxidty of di (2-ethylhexyl) phthalate in rats. Toxicol. Sci. 55(2):2000a;433-443.
    • (2000) Toxicol. Sci. , vol.55 , Issue.2 , pp. 433-443
    • David, R.M.1    Moore, M.R.2    Finney, D.C.3    Guest, D.4
  • 6
    • 0034524362 scopus 로고    scopus 로고
    • Chronic toxicity of di (2-ethylhexyl) phthalate in mice
    • David R.M., Moore M.R., Finney D.C., Guest D. Chronic toxicity of di (2-ethylhexyl) phthalate in mice. Toxicol. Sci. 58(2):2000b;339-349.
    • (2000) Toxicol. Sci. , vol.58 , Issue.2 , pp. 339-349
    • David, R.M.1    Moore, M.R.2    Finney, D.C.3    Guest, D.4
  • 7
    • 0034824247 scopus 로고    scopus 로고
    • Reversibility of the chronic toxidty of di (2-ethylhexyl) phthalate
    • David R.M., Moore M.R., Finney D.C., Guest D. Reversibility of the chronic toxidty of di (2-ethylhexyl) phthalate. Toxicol. Pathol. 29(4):2001;430-439.
    • (2001) Toxicol. Pathol. , vol.29 , Issue.4 , pp. 430-439
    • David, R.M.1    Moore, M.R.2    Finney, D.C.3    Guest, D.4
  • 8
    • 0023751785 scopus 로고
    • Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di (2-ethylhexyl) phthalate and the recovery of fertility as adults
    • Dostal L.A., Chapin I.L.E., Stefanski S.A., Harris M.W., Schwetz M.W. Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di (2-ethylhexyl) phthalate and the recovery of fertility as adults. Toxicol. Appl. Pharmacol. 95:1988;104-121.
    • (1988) Toxicol. Appl. Pharmacol. , vol.95 , pp. 104-121
    • Dostal, L.A.1    Chapin, I.L.E.2    Stefanski, S.A.3    Harris, M.W.4    Schwetz, M.W.5
  • 10
    • 0027510136 scopus 로고
    • Effects of mono-(2-ethylhexyl) phthalate, a testicular toxicant, on follicle-stimulating hormone binding to membranes from cultured rat Sertoli cells
    • Grasso P., Heindel J.J., Powell C.J., Reichert L.E. Jr. Effects of mono-(2-ethylhexyl) phthalate, a testicular toxicant, on follicle-stimulating hormone binding to membranes from cultured rat Sertoli cells. Biol. Reprod. 48(3):1993;454-459.
    • (1993) Biol. Reprod. , vol.48 , Issue.3 , pp. 454-459
    • Grasso, P.1    Heindel, J.J.2    Powell, C.J.3    Reichert Jr., L.E.4
  • 11
    • 0343090362 scopus 로고    scopus 로고
    • Administration of potentially antiandrogenic pesticides (procymidon, linuron, iprodion, chiozolinate, p,p′-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl-phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produce diverse profile of reproductive malformations in the male rat
    • Gray L.E., Wolf C., Lambright C., Mann P., Price M., Cooper R.L., Ostby J. Administration of potentially antiandrogenic pesticides (procymidon, linuron, iprodion, chiozolinate, p,p′-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl-phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produce diverse profile of reproductive malformations in the male rat. Toxicol. Ind. Health. 15(1-2):1999;94-118.
    • (1999) Toxicol. Ind. Health , vol.15 , Issue.1-2 , pp. 94-118
    • Gray, L.E.1    Wolf, C.2    Lambright, C.3    Mann, P.4    Price, M.5    Cooper, R.L.6    Ostby, J.7
  • 12
    • 0034523473 scopus 로고    scopus 로고
    • Perinatal exposure to phthalates DEHP, BBP, and DINP but not DEP, DMP, DOTP alters sexual differentiation of the male rat
    • Gray L.E. Jr., Ostby J., Furr J., Price M., Veeramachaneni D.N., Parks L. Perinatal exposure to phthalates DEHP, BBP, and DINP but not DEP, DMP, DOTP alters sexual differentiation of the male rat. Toxicol. Sci. 58(2):2000;350-365.
    • (2000) Toxicol. Sci. , vol.58 , Issue.2 , pp. 350-365
    • Gray Jr., L.E.1    Ostby, J.2    Furr, J.3    Price, M.4    Veeramachaneni, D.N.5    Parks, L.6
  • 14
    • 0030890609 scopus 로고    scopus 로고
    • The Fas system is a key regulator of germ cell apoptosis in the testis
    • Lee J., Richburg J.H., Yunkin S.C., Boekelheide K. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology. 138:1997;2081-2088.
    • (1997) Endocrinology , vol.138 , pp. 2081-2088
    • Lee, J.1    Richburg, J.H.2    Yunkin, S.C.3    Boekelheide, K.4
  • 15
    • 0032910202 scopus 로고    scopus 로고
    • The Fas system, a regulator of testicular germ cell apoptosis is differentially upregulated in Sertoli cell versus germ cell injury of the testis
    • Lee J., Richburg J.H., Shipp E.B., Meistrich M.L., Boekelheide K. The Fas system, a regulator of testicular germ cell apoptosis is differentially upregulated in Sertoli cell versus germ cell injury of the testis. Endocrinology. 140:1999;852-858.
    • (1999) Endocrinology , vol.140 , pp. 852-858
    • Lee, J.1    Richburg, J.H.2    Shipp, E.B.3    Meistrich, M.L.4    Boekelheide, K.5
  • 16
    • 0032875814 scopus 로고    scopus 로고
    • Cocaine induced apoptosis in rat testis
    • Li H., Jiang Y., Rajpurkar A., Dunber J.C. Cocaine induced apoptosis in rat testis. J. Urol. 162:1999;213-216.
    • (1999) J. Urol. , vol.162 , pp. 213-216
    • Li, H.1    Jiang, Y.2    Rajpurkar, A.3    Dunber, J.C.4
  • 17
    • 0023711161 scopus 로고
    • Developmental toxicity in rats after inhalation exposure of di-2-ethylhexylphthalate (DEHP)
    • Merkle J., Klimisch H.J., Jackh R. Developmental toxicity in rats after inhalation exposure of di-2-ethylhexylphthalate (DEHP). Toxicol. Lett. 42:1988;215-223.
    • (1988) Toxicol. Lett. , vol.42 , pp. 215-223
    • Merkle, J.1    Klimisch, H.J.2    Jackh, R.3
  • 18
    • 15844412409 scopus 로고    scopus 로고
    • Flice, a novel FADD-homologous ICE/CED-3-like protenase is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M., Chinnaiyan A.M., Kischkel P.C., Rourke K., Shevchenko A. Flice, a novel FADD-homologous ICE/CED-3-like protenase is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:1996;817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, P.C.3    Rourke, K.4    Shevchenko, A.5
  • 19
    • 0034521058 scopus 로고    scopus 로고
    • The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat
    • Parks L.G., Ostby J.S., Lambright C.R., Abott B.D., Kleinefelter G.R., Barlow N.J., Gray L.E. The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol. Sci. 58(2):2000;339-349.
    • (2000) Toxicol. Sci. , vol.58 , Issue.2 , pp. 339-349
    • Parks, L.G.1    Ostby, J.S.2    Lambright, C.R.3    Abott, B.D.4    Kleinefelter, G.R.5    Barlow, N.J.6    Gray, L.E.7
  • 20
    • 0022973652 scopus 로고
    • Effect of di (2-ethylhexyl) phthalate (DEHP) on spermatogenesis in adult rats
    • Parmer D., Srivastava S.P., Seth P.K. Effect of di (2-ethylhexyl) phthalate (DEHP) on spermatogenesis in adult rats. Toxicology. 42:1986;47-55.
    • (1986) Toxicology , vol.42 , pp. 47-55
    • Parmer, D.1    Srivastava, S.P.2    Seth, P.K.3
  • 21
    • 0029995352 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes
    • Richburg J.H., Boekelheide K. Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes. Toxicol. Appl. Pharmacol. 137:1996;42-50.
    • (1996) Toxicol. Appl. Pharmacol. , vol.137 , pp. 42-50
    • Richburg, J.H.1    Boekelheide, K.2
  • 22
    • 0345440129 scopus 로고    scopus 로고
    • Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testis after exposure to mono (2-ethylhexyl) phthalate (MEHP)
    • Richburg J.H., Nanez A., Gao H. Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testis after exposure to mono (2-ethylhexyl) phthalate (MEHP). Toxicol. Appl. Pharmacol. 160(3):1999;271-278.
    • (1999) Toxicol. Appl. Pharmacol. , vol.160 , Issue.3 , pp. 271-278
    • Richburg, J.H.1    Nanez, A.2    Gao, H.3
  • 23
    • 0034465421 scopus 로고    scopus 로고
    • Sensivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand
    • Richburg J.H., Nanez A., Williams L.R., Embree M.E., Boekelheide K. Sensivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. 141(2):2000;787-793.
    • (2000) Endocrinology , vol.141 , Issue.2 , pp. 787-793
    • Richburg, J.H.1    Nanez, A.2    Williams, L.R.3    Embree, M.E.4    Boekelheide, K.5
  • 24
    • 0031023614 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation is detected by a semiquantitative ligation-mediated PCR of blunt DNA ends
    • Staley K., Blaschke A.J., Chun J. Apoptotic DNA fragmentation is detected by a semiquantitative ligation-mediated PCR of blunt DNA ends. Cell Deth. Diff. 4:1997;66.
    • (1997) Cell Deth. Diff. , vol.4 , pp. 66
    • Staley, K.1    Blaschke, A.J.2    Chun, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.