Dietary fish oil decreases low-density-lipoprotein clearance in nonhuman primates

American Journal of Clinical Nutrition

Volumn 64, Issue 2, 1996, Pages 215-221

  Schectman, Gordon ^a   Boerboom, Lawrence E ^b   Hannah, Judy ^b   Howard, Barbara V ^b   Mueller, Robert A ^b   Kissebah, Ahmed H ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b NONE

Author keywords

apolipoprotein B; Fish oil; low density lipoprotein; n 3 fatty acids

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL ESTER; FISH OIL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; OLIVE OIL; OMEGA 3 FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CHO CELL; CONTROLLED STUDY; DRUG FORMULATION; HYPERCHOLESTEROLEMIA; LIPID COMPOSITION; LIPOPROTEIN METABOLISM; MACACA; MALE; NONHUMAN; NUTRITIONAL SUPPORT; ORAL DRUG ADMINISTRATION; RECEPTOR AFFINITY;

EID: 0029893968     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/64.2.215     Document Type: Article

References (55)

1. Harris W. Fish oils and plasma lipid and lipoprotein metabolism in humans: a critical review. J Lipid Res 1989;30:785-807.
2. Schectman G, Kaul S, Kissebah A. Heterogeneity of low density lipoprotein responses to fish oil concentrate in hypertriglyceridemic subjects. Arteriosclerosis 1989;9:345-54.
3. Parks JS, Gebre AK. Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys. J Lipid Res 1991;32:305-15.
4. Parks J, Bullock B. Effect of fish oil versus lard diets on the chemical and physical properties of low density lipoproteins of nonhuman primates. J Lipid Res 1987;28:173-82.
5. Abbey M, Clifton P, McMurchie E, McIntosh G, Nestel P. Effect of a high fat/cholesterol diet with or without eicosapentaenoic acid on plasma lipids, lipoproteins and lipid transfer protein activity in the marmoset. Atherosclerosis 1990;81:163-84.
6. Roach P, Kambouris A, Trimble R, Topping D, Nestel P. The effects of dietary fish oil on hepatic high density and low density lipoprotein receptor activities in the rat. FEBS Lett 1987;222:159-62.
7. Wong S, Nestel P. Eicosapentaenoic acid inhibits the secretion of triacylglycerol and of apoprotein B and the binding of LDL in Hep G2 cells. Atherosclerosis 1987;67:139-46.
8. Huff MW, Telford DE. Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein. Arteriosclerosis 1989;9:58-66.
9. Illingworth D, Harris W, Connor W. Inhibition of low density lipoprotein synthesis by dietary omega-3 fatty acids in humans. Arteriosclerosis 1984;4:270-5.
10. Ventura MA, Woollett LA, Spady DK. Dietary fish oil stimulates hepatic low density lipoprotein transport in the rat. J Clin Invest 1989;84:528-37.
11. Krieger M. Complementation of mutations in the LDL pathway of receptor-mediated endocytosis by cocultivation of LDL receptor-defective hamster cell mutants. Cell 1983;33:413-22.
12. Davis CG, Elhammer A, Russell DW, et al. Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts. J Biol Chem 1986;261:2828-38.
13. McFarlane A. Efficient trace labeling of proteins with iodine. Nature 1958;182:53-4.
14. Goldstein J, Basu S, Brown M. Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol 1983;98:241-60.
15. Hara H, Howard B. Characterization of LDL binding in TR 715-19 cells: a high capacity, stable line for evaluating the binding of LDL to the human LDL receptor. Atherosclerosis 1990;83:155-65.
16. Scatchard G. The attractions of proteins for small molecules and ions. Ann N Y Acad Sci 1949;51:660-72.
17. Lindgren F, Jensen J, Hatch F. The isolation and quantitative analysis of serum lipoproteins. In: Nelson GJ, ed. Blood lipids and lipoproteins: quantitation and lipoprotein metabolism. New York: John Wiley & Sons, 1972:181-274.
18. Laner T, Shroder W, Levy R. The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia. J Clin Invest 1972;53:1528-36.
19. Egusa G, Brady D, Grundy S, Howard B. Isopropanol precipitation method for determining apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B. J Lipid Res 1983;24:1261-7.
20. Mathews C. The theory of tracer experiments with 131-I labeled plasma proteins. Phys Med Biol 1957;2:36-53.
21. Reichl D. Lipoproteins of human peripheral lymph. Eur Heart J 1990;11(suppl):E230-6.
22. Sloop C, Dory L, Roheim P. Interstitial fluid lipoproteins. J Lipid Res 1987;28:225-37.
23. Berman M, Beltz W, Greif P, Chabay R, Boston R. CONSAM user's guide. Bethesda, MD: National Cancer Institute, National Institutes of Health, 1983.
24. Goldberg I, Le N, Leeman B, Brown W, Lindgren F. Evidence of heterogeneity of low-density lipoprotein metabolism in the cynomolgus monkey. Biochim Biophys Acta 1986;879:179-85.
25. Marzetta C, Rudel L. A species comparison of low density lipoprotein heterogeneity in nonhuman primates fed atherogenic diets. J Lipid Res 1986;27:753-62.
26. Foster D, Chait A, Albers J, Failor R, Harris C, Brunzell J. Evidence for kinetic heterogeneity among human low density lipoproteins. Metabolism 1986;35:685-96.
27. Schectman G, Kaul S, Mueller R, Borden E, Kissebah A. The effect of interferon on the metabolism of low density lipoproteins. Arterioscler Thromb 1992;12:1053-62.
28. Lowry O, Rosebrough N, Fair A, Randall R. Protein measurement with Folin phenol reagent. J Biol Chem 1951;193:265-75.
29. Burstein M, Scholnick H, Morfin R. Rapid method for the isolation of lipoproteins from serum by precipitation with polyanions. J Lipid Res 1970;11:583-98.
30. Fiske C, Subbarow Y. The calorimetric determination of phosphorus. J Biol Chem 1925;66:375-8.
31. Folch J, Leer M, Sloane-Stanley G. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957;226:497-509.
32. Hirsch J, Ahrens E. The separation of complex lipid mixtures by the use of silic acid chromatography. J Biol Chem 1958;233:311-20.
33. Cherayil G. Sialic acid and fatty acid concentrations in lymphocytes, red blood cells and plasma from patients with multiple sclerosis. J Neurol Sci 1984;63:1-10.
34. Linga V, Leight M, Clair RS, Parks J. Dietary fish oil modification of cynomolgus monkey low density lipoproteins results in decreased binding and cholesteryl ester accumulation by cultured fibroblasts. J Lipid Res 1993;34:769-78.
35. Linga V, Leight M, Curtiss L, Marcel Y, Clair RS, Parks J. Dietary fish oil-induced decrease in low density lipoprotein binding to fibroblasts is mediated by apolipoprotein E. J Lipid Res 1994;35:491-500.
36. Huff M, Telford D, Edmonds B, McDonald C, Evans A. Lipoprotein lipases, lipoprotein density gradient profile and LDL receptor activity in miniature pigs fed fish oil and corn oil. Biochim Biophys Acta 1993;1210:113-22.
37. Spady D, Horton J, Cuthbert J. Regulatory effects of n-3 polyunsaturated fatty acids on hepatic LDL uptake in the hamster and rat. J Lipid Res 1995;36:1009-20.
38. Lindsey S, Pronczuk A, Hayes K. Low density lipoprotein from humans supplemented with n-3 fatty acids depresses both LDL receptor activity and LDL mRNA abundance in HepG2 cells. J Lipid Res 1992;33:647-58.
39. Homma Y, Ohshima K, Yamaguchi H, Nakamura H, Araki G, Goto Y. Effects of eicosapentaenoic acid on plasma lipoprotein subfractions and activities of lecithin:cholesterol acyltransferase and lipid transfer protein. Atherosclerosis 1991;91:145-53.
40. Abbey M, Clifton P, Kestin M, Belling B, Nestel P. Effect of fish oil on lipoproteins, lecithin:cholesterol acyltransferase, and lipid transfer protein activity in humans. Arteriosclerosis 1990;10:85-94.
41. Bagdade J, Ritter M, Davidson M, Subbaiah P. Effect of marine lipids on cholesteryl ester transfer and lipoprotein composition in patients with hypercholesterolemia. Arterioscler Thromb 1992;12:1146-52.
42. Parks J, Thuren T, Schmitt J. Inhibition of lecithin:cholesterol acyltransferase activity by synthetic phosphatidylcholine species containing eicosapentaenoic acid or docosahexaenic acid in the sn-2 position. J Lipid Res 1992;33:879-87.
43. Soltys P, Mazzone T, Wissler R, et al. Effects of feeding fish oil on the properties of lipoproteins isolated from rhesus monkeys consuming an atherogenic diet. Atherosclerosis 1989;76:103-15.
44. Pownall H, Shepherd J, Mantulin W, Sklar L, Gotto A. Effect of saturated and polyunsaturated fat diets on the composition and structure of human low-density lipoproteins. Atherosclerosis 1980;36:299-314.
45. Vega G, Groszek E, Wolf R, Grundy S. Influence of polyunsaturated fats on composition of plasma lipoproteins and apolipoproteins. J Lipid Res 1982;23:811-22.
46. Nestel P. Effects of n-3 fatty acids on lipid metabolism. Annu Rev Nutr 1990;10:149-67.
47. Hornstra G. The significance of fish and fish-oil enriched food for prevention and therapy of cardiovascular disease. In: Vergroesen A, Crawford M, eds. The role of fats in human nutrition. New York: Academic Press, 1989:152-9.
48. Kinsella JE, Lokesh B, Stone RA. Dietary n-3 polyunsaturaled fatty acids and amelioration of cardiovascular disease: possible mechanisms. Am J Clin Nutr 1990;52:1-9.
49. Wilt T, Lofgren R, Nichol K, et al. Fish oil supplementation does not lower plasma cholesterol in men with hypercholesterolemia. Ann Intern Med 1989;111:900-5.
50. Demke D, Peters G, Linet O, Metzler C, Klott K. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70:73-80.
51. Dart A, Riemersma R, Oliver M. Effects of MaxEpa on serum lipids in hypercholesterolemic subjects. Atherosclerosis 1989;80:119-26.
52. Subbaiah P, Davidson M, Ritter M, Buchanan W, Bagdade J. Effects of dietary supplementation with marine lipid concentrate on the plasma lipoprotein composition of hypercholesterolemic patients. Atherosclerosis 1989;79:157-64.
53. Davidson M, Burns J, Subbaiah P, Conn M, Drennan K. Marine oil capsule therapy for the treatment of hyperlipidemia. Arch Intern Med 1991;151:1732-40.
54. Sirtori CR, Gatti E, Tremoli E, et al. Olive oil, corn oil, and n-3 fatty acids differently affect lipids, lipoproteins, platelets, and Superoxide formation in type II hypercholesterolemia. Am J Clin Nutr 1992;56:113-22.
55. Schmidt EB, Kristensen SD, Caterina RD, Illingworth DR. The effects of n-3 fatty acids on plasma lipids and lipoproteins and other cardiovascular risk factors in patients with hyperlipidemia. Atherosclerosis 1993;103:107-21.