Effects of lifestyle modification in polycystic ovarian syndrome

Reproductive BioMedicine Online

Volumn 12, Issue 5, 2006, Pages 569-578

  Moran, Lisa J ^a,b   Brinkworth, Grant ^a   Noakes, Manny ^a   Norman, Robert J ^b  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Appetite regulation; Dietary composition; Exercise; Lifestyle modification

Indexed keywords

INSULIN;

AEROBIC EXERCISE; ANOVULATION; ARTICLE; BEHAVIOR THERAPY; CLINICAL TRIAL; DIABETES MELLITUS; DIET THERAPY; EXERCISE; FITNESS; HUMAN; INFERTILITY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESTYLE; LONG TERM CARE; METABOLIC SYNDROME X; OBESITY; OVARY POLYCYSTIC DISEASE; PREVALENCE; RISK ASSESSMENT; WEIGHT REDUCTION;

EID: 33646431229     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)61182-0     Document Type: Article

References (109)

1. Abbott DH, Barnett DK, Bruns CM et al. 2005 Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome? Human Reproduction Update 11, 357-374.
2. Acien P, Quereda F, Matallin P et al. 1999 Insulin, androgens, and obesity in women with and without polycystic ovary syndrome: a heterogeneous group of disorders. Fertility and Sterility 72, 32-40.
3. Altuntas Y, Bilir M, Ucak S et al. 2005 Reactive hypoglycemia in lean young women with PCOS and correlations with insulin sensitivity and with beta cell function. European Journal of Obstetrics Gynecology and Reproductive Biology 119, 198-205.
4. American College of Sports Medicine 2000 Guidelines for Exercise Testing and Prescription, Lippincott Williams and Wilkins, Philadelphia.
5. Andersen RE, Wadden TA, Bartlett SJ et al. 1999 Effects of lifestyle activity vs structured aerobic exercise in obese women: a randomized trial. Journal of the American Medical Association 281, 335-340.
6. Anderson JW, Konz EC, Frederich RC et al. 2001 Long-term weight-loss maintenance: a meta-analysis of US studies. American Journal of Clinical Nutrition 74, 579-584.
7. Apridonidze T, Essah PA, Iuorno MJ et al. 2004 Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 90, 1929-1945.
8. Australian Institute of Health and Welfare (AIHW) 2004 Australia's Health 2004: the ninth biannual health report of the AIHW. Australian Institute of Health and Welfare, Canberra.
9. Azziz R, Marin C, Hoq L et al. 2005 Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. Journal of Clinical Endocrinology and Metabolism 90, 4650-4658.
10. Azziz R, Woods KS, Reyna R et al. 2004 The prevalence and features of the polycystic ovary syndrome in an unselected population. Journal of Clinical Endocrinology and Metabolism 89, 2745-2749.
11. Ballor DL, Katch VL, Becque MD et al. 1988 Resistance weight training during caloric restriction enhances lean body weight maintenance. American Journal of Clinical Nutrition 47, 19-25.
12. Barbieri RL, Makris A, Randall RW et al. 1986 Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism. Journal of Clinical Endocrinology and Metabolism 62, 904-910.
13. Bowen J, Noakes M, Clifton PM 2004 A high dairy protein, high-calcium diet minimizes bone turnover in overweight adults during weight loss. Journal of Nutrition 134, 568-573.
14. Brand JC, Colagiuri S, Crossman S et al. 1991 Low-glycemic index foods improve long-term glycemic control in NIDDM. Diabetes Care 14, 95-101.
15. Brankston GN, Mitchell BF, Ryan EA et al. 2004 Resistance exercise decreases the need for insulin in overweight women with gestational diabetes mellitus. American Journal of Obstetrics and Gynecology 190, 188-193.
16. Brown AJ, Aiken LB, Setji T et al. 2005 Effect of exercise without weight loss on insulin resistance in women with polycystic ovary syndrome: a randomised, controlled study. In 3rd Annual Meeting of the Androgen Excess Society San Diego, California, June 2005, p. 28.
17. Bung P, Artal R, Khodiguian N et al. 1991 Exercise in gestational diabetes. An optional therapeutic approach? Diabetes 40 (Suppl. 2), 182-185.
18. Carels RA, Darby LA, Douglass OM et al. 2005 Education on the glycemic index of foods fails to improve treatment outcomes in a behavioral weight loss program. Eating Behaviour 6, 145-150.
19. Carroll S, Dudfield M 2004 What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome. Sports Medicine 34, 371-418.
20. Clark AM, Thornley B, Tomlinson L et al. 1998 Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Human Reproduction 13, 1502-1505.
21. Corbould A, Kim YB, Youngren JF et al. 2005 Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. American Journal of Physiology-Endocrinology and Metabolism 288, E1047-1054.
22. Coviello AD, Legro RS, Dunaif A 2005 Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. Journal of Clinical Endocrinology and Metabolism Rapid Electronic Publication 25 October 2005.
23. Cresswell JL, Barker DJ, Osmond C et al. 1997 Fetal growth, length of gestation, and polycystic ovaries in adult life. Lancet 350, 1131-1135.
24. Cuff DJ, Meneilly GS, Martin A et al. 2003 Effective exercise modality to reduce insulin resistance in women with type 2 diabetes. Diabetes Care 26, 2977-2982.
25. Cummings DE, Purnell JQ, Frayo RS et al. 2001 A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50, 1714-1719.
26. Dale PO, Tanbo T, Vaaler S et al. 1992 Body weight, hyperinsulinemia, and gonadotropin levels in the polycystic ovarian syndrome: evidence of two distinct populations. Fertility and Sterility 58, 487-491.
27. Davey GJG, Roberts JD, Patel S et al. 2000 Effects of exercise on insulin resistance in South Asians and Europeans. Journal of Exercise Physiology Online 3, 6-11.
28. Degen L, Matzinger D, Drewe J et al. 2001 The effect of cholecystokinin in controlling appetite and food intake in humans. Peptides 22, 1265-1269.
29. Dempsey JC, Butler CL, Williams MA 2005 No need for a pregnant pause: physical activity may reduce the occurrence of gestational diabetes mellitus and preeclampsia. Exercise and Sports Science Reviews 33, 141-149.
30. DeUgarte CM, Bartolucci AA, Azziz R 2005 Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment. Fertility and Sterility 83, 1454-1460.
31. Devlin JT, Hirshman M, Horton ED et al. 1987 Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after single bout of exercise. Diabetes 36, 434-439.
32. Donnelly JE, Smith B, Jacobsen DJ et al. 2004 The role of exercise for weight loss and maintenance. Best Practice and Research in Clinical Gastroenterology 18, 1009-1029.
33. Due A, Toubro S, Skov AR et al. 2004 Effect of normal-fat diets, either medium or high in protein, on body weight in overweight subjects: a randomised 1-year trial. International Journal of Obesity and Related Metabolic Disorders 28, 1283-1290.
34. Duncan GE, Perri MG, Theriaque DW et al. 2003 Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care 26, 557-562.
35. Dunn AL, Marcus BH, Kampert JB et al. 1999 Comparison of lifestyle and structured interventions to increase physical activity and cardiorespiratory fitness: a randomized trial. Journal of the American Medical Association 281, 327-334.
36. Ehrmann DA, Liljenquist DR, Kasza K et al. 2005 Prevalence and Predictors of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome (PCOS). Journal of Clinical Endocrinology and Metabolism 98, 41-53.
37. Ehrmann DA, Barnes RB, Rosenfield RL et al. 1999 Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 22, 141-146.
38. Elfhag K, Rossner S 2005 Who succeeds in maintaining weight loss? A conceptual review of factors associated with weight loss maintenance and weight regain. Obesity Reviews 6, 67-85.
39. English PJ, Ghatei MA, Malik IA et al. 2002 Food fails to suppress ghrelin levels in obese humans. Journal of Clinical Endocrinology and Metabolism 87, 2984.
40. Eriksson J, Tuominen J, Valle T et al. 1998 Aerobic endurance exercise or circuit-type resistance training for individuals with impaired glucose tolerance? Hormone and Metabolic Research 30, 37-41.
41. Farnsworth E, Luscombe ND, Noakes M et al. 2003 Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women. American Journal of Clinical Nutrition 78, 31-39.
42. Galletly C, Clark A, Tomlinson L et al. 1996 A group program for obese, infertile women: weight loss and improved psychological health. Journal of Psychosomatic Obstetrics and Gynaecology 17, 125-128.
43. Geliebter A, Maher MM, Gerace L et al. 1997 Effects of strength or aerobic training on body composition, resting metabolic rate, and peak oxygen consumption in obese dieting subjects. American Journal of Clinical Nutrition 66, 557-563.
44. Glueck CJ, Wang P, Goldenberg N et al. 2002 Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. Human Reproduction 17, 2858-2864.
45. Gorin AA, Phelan S, Hill JO et al. 2004 Medical triggers are associated with better short- and long-term weight loss outcomes. Preventative Medicine 39, 612-616.
46. Haakova L, Cibula D, Rezabek K et al. 2003 Pregnancy outcome in women with PCOS and in controls matched by age and weight. Human Reproduction 18, 1438-1441.
47. Hamilton-Fairley D, Kiddy D, Anyaoku V et al. 1993 Response of sex hormone binding globulin and insulin-like growth factor binding protein-1 to an oral glucose tolerance test in obese women with polycystic ovary syndrome before and after calorie restriction. Clinical Endocrinology 39, 363-367.
48. Hart R, Hickey M, Franks S 2004 Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome. Best Practice and Research in Clinical Obstetrics and Gynaecology 18, 671-683.
49. Herman WH, Hoerger TJ, Brandle M et al. 2005 The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance. Annals of Internal Medicine 142, 323-332.
50. Hills AP, Byrne NM 2004 Physical activity in the management of obesity. Clinical Dermatology 22, 315-318.
51. Hirschberg AL, Naessen S, Stridsberg M et al. 2004 Impaired cholecystokinin secretion and disturbed appetite regulation in women with polycystic ovary syndrome. Gynecological Endocrinolology 19, 79-87.
52. Hoeger KM, Kochman L, Wixom N et al. 2004 A randomized, 48-week, placebo-controlled trial of intensive lifestyle modification and/or metformin therapy in overweight women with polycystic ovary syndrome: a pilot study. Fertility and Sterility 82, 421-429.
53. Huber-Buchholz MM, Carey DG, Norman RJ 1999 Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: role of insulin sensitivity and luteinizing hormone. Journal of Clinical Endocrinology and Metabolism 84, 1470-1474.
54. Ibanez L, Ferrer A, Ong K et al. 2004 Insulin sensitization early after menarche prevents progression from precocious pubarche to polycystic ovary syndrome. Journal of Pediatrics 144, 23-29.
55. Ibanez L, Potau N, Francois I et al. 1998 Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: relation to reduced fetal growth. Journal of Clinical Endocrinology and Metabolism 83, 3558-3562.
56. Jacobsen DJ, Donnelly JE, Snyder-Heelan K et al. 2003 Adherence and attrition with intermittent and continuous exercise in overweight women. International Journal of Sports Medicine 24, 459-464.
57. Jakicic JM, Clark K, Coleman E et al. 2001 American College of Sports Medicine position stand. Appropriate intervention strategies for weight loss and prevention of weight regain for adults. Medicine and Science in Sports and Exercise 33, 2145-2156.
58. Jakicic JM, Winters C, Lang W et al. 1999 Effects of intermittent exercise and use of home exercise equipment on adherence, weight loss, and fitness in overweight women: a randomized trial. Journal of the American Medical Association 282, 1554-1560.
59. Jakubowicz DJ, Nestler JE 1997 17 alpha-hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome offer dietary weight loss. Journal of Clinical Endocrinology and Metabolism 82, 556-560.
60. Knochenhauer ES, Key TJ, Kahsar-Miller M et al. 1998 Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. Journal of Clinical Endocrinology and Metabolism 83, 3078-3082.
61. Knowler WC, Barrett-Connor E, Fowler SE et al. 2002 Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal of Medicine 346, 393-403.
62. Laitinen J, Taponen S, Martikainen H et al. 2003 Body size from birth to adulthood as a predictor of self-reported polycystic ovary syndrome symptoms. International Journal of Obesity and Related Metabolic Disorders 27, 710-715.
63. La Marca A, Artensio AC, Stabile G et al. 2005 Metformin treatment of PCOS during adolescence and the reproductive period. European Journal of Obstetrics Gynecology and Reproductive Biology 121, 3-7.
64. Legro RS, Kunselman AR, Dodson WC et al. 1999 Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. Journal of Clinical Endocrinology and Metabolism 84, 165-169.
65. Ludwig DS 2000 Dietary glycemic index and obesity. Journal of Nutrition 130, 280S-283S.
66. Luscombe ND, Noakes M, Clifton PM 1999 Diets high and low in glycemic index versus high monounsaturated fat diets: effects on glucose and lipid metabolism in NIDDM. European Journal of Clinical Nutrition 53, 473-478.
67. Luscombe-Marsh ND, Noakes M, Wittert GA et al. 2005 Carbohydrate-restricted diets high in either monounsaturated fat or protein are equally effective at promoting fat loss and improving blood lipids. American Journal of Clinical Nutrition 81, 762-772.
68. McAuley KA, Williams SM, Mann JI et al. 2002 Intensive lifestyle changes are necessary to improve insulin sensitivity: a randomized controlled trial. Diabetes Care 25, 445-452.
69. McTiernan A, Tworoger SS, Rajan KB et al. 2004 Effect of exercise on serum androgens in postmenopausal women: a 12-month randomized clinical trial. Cancer Epidemiology Biomarkers and Prevention 13, 1099-1105.
70. Mikines KJ, Sonne B, Farrell PA et al. 1988 Effect of physical exercise on sensitivity and responsiveness to insulin in humans. American Journal of Physiology-Endocrinology and Metabolism 254, E248-259.
71. Mikola M, Hiilesmaa V, Halttunen M et al. 2001 Obstetric outcome in women with polycystic ovarian syndrome. Human Reproduction 16, 226-229.
72. Moran LJ, Luscombe-Marsh ND, Noakes M et al. 2005 The satiating effect of dietary protein is unrelated to post-prandial ghrelin secretion. Journal of Clinical Endocrinology and Metabolism 89, 3337-3344.
73. Moran LJ, Noakes M, Clifton PM et al. 2004a Short term energy restriction (using meal replacements) improves reproductive parameters in polycystic ovary syndrome. Asia Pacific Journal of Clinical Nutrition 13, S88.
74. Moran LJ, Noakes M, Clifton PM et al. 2004b Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Journal of Clinical Endocrinology and Metabolism 89, 3337-3344.
75. Moran LJ, Noakes M, Clifton PM et al. 2003 Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 88, 812-819.
76. Noakes M, Foster PR, Keogh JB et al. 2004 Meal replacements are as effective as structured weight-loss diets for treating obesity in adults with features of metabolic syndrome. Journal of Nutrition 134, 1894-1899.
77. Norman RJ, Davies MJ, Lord J et al. 2002 The role of lifestyle modification in polycystic ovary syndrome. Trends in Endocrinology and Metabolism 13, 251-257.
78. Orchard TJ, Temprosa M, Goldberg R et al. 2005 The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Annals of Internal Medicine 142, 611-619.
79. Palmert MR, Gordon CM, Kartashov AI et al. 2002 Screening for abnormal glucose tolerance in adolescents with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 87, 1017-1023.
80. Paradisi G, Steinberg HO, Hempfling A et al. 2001 Polycystic ovary syndrome is associated with endothelial dysfunction. Circulation 103, 1410-1415.
81. Park SK, Park JH, Kwon YC et al. 2003 The effect of combined aerobic and resistance exercise training on abdominal fat in obese middle-aged women. Journal of Physiological Anthropology and Applied Human Science 22, 129-135.
82. Parker B, Noakes M, Luscombe N et al. 2002 Effect of a high-protein, high-monounsaturated fat weight loss diet on glycemic control and lipid levels in type 2 diabetes. Diabetes Care 25, 425-430.
83. Pasquali R, Gambineri A, Biscotti D et al. 2000 Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 85, 2767-2774.
84. Pawlak DB, Ebbeling CB, Ludwig DS 2002 Should obese patients be counselled to follow a low-glycaemic index diet? Yes. Obesity Reviews 3, 235-243.
85. Perseghin G, Price TB, Petersen KF et al. 1996 Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. New England Journal of Medicine 335, 1357-1362.
86. Pirozzo S, Summerbell C, Cameron C et al. 2003 Should we recommend low-fat diets for obesity? Obesity Reviews 4, 83-90.
87. Pi-Sunyer FX, Becker DM, Bouchard C et al. 1998 Expert Panel of the Identification, Evaluation and Treatment of Overweight in Adults: clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. American Journal of Clinical Nutrition 68, 899-917.
88. Plymate SR, Matej LA, Jones RE et al. 1988 Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin. Journal of Clinical Endocrinology and Metabolism 67, 460-464.
89. Poehlman ET, Dvorak RV, DeNino WF et al. 2000 Effects of resistance training and endurance training on insulin sensitivity in nonobese, young women: a controlled randomized trial. Journal of Clinical Endocrinology and Metabolism 85, 2463-2468.
90. Raben A 2002 Should obese patients be counselled to follow a low-glycaemic index diet? No. Obesity Reviews 3, 245-256.
91. Randeva HS, Lewandowski KC, Drzewoski J et al. 2002 Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 87, 4496-4501.
92. Reaven GM 2005 The insulin resistance syndrome: definition and dietary approaches to treatment. Annual Review of Nutrition 25, 391-406.
93. Rosenfield RL, Ghai K, Ehrmann DA et al. 2000 Diagnosis of the polycystic ovary syndrome in adolescence: comparison of adolescent and adult hyperandrogenism. Journal of Pediatric Endocrinology and Metabolism 13 (Suppl. 5), 1285-1289.
94. Ross R, Dagnone D, Jones PJ et al. 2000 Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial. Annals of Internal Medicine 133, 92-103.
95. Sadrzadeh S, Klip WA, Broekmans FJ et al. 2003 Birth weight and age at menarche in patients with polycystic ovary syndrome or diminished ovarian reserve, in a retrospective cohort. Human Reproduction 18, 2225-2230.
96. Samaha FF, Iqbal N, Seshadri P et al. 2003 A low-carbohydrate as compared with a low-fat diet in severe obesity. New England Journal of Medicine 348, 2074-2081.
97. Saris WH, Blair SN, van Baak MA et al. 2003 How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock Conference and consensus statement. Obesity Reviews 4, 101-114.
98. Scalzo K 2000 Case problem: dietary recommendations to combat obesity, insulin resistance, and other concerns related to polycystic ovary syndrome. Journal of the American Dietetic Association 100, 955-957; discussion 957-960.
99. Skov AR, Toubro S, Ronn B et al. 1999 Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity. International Journal of Obesity and Related Metabolic Disorders 23, 528-536.
100. Slabber M, Barnard HC, Kuyl JM et al. 1994 Effects of a low-insulin-response, energy-restricted diet on weight loss and plasma insulin concentrations in hyperinsulinemic obese females. American Journal of Clinical Nutrition 60, 48-53.
101. Sloth B, Krog-Mikkelsen I, Flint A et al. 2004 No difference in body weight decrease between a low-glycemic-index and a high-glycemic-index diet but reduced LDL cholesterol after 10-wk ad libitum intake of the low-glycemic-index diet. American Journal of Clinical Nutrition 80, 337-347.
102. Solomon CG 1999 The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks. Endocrinology and Metabolism Clinics of North America 28, 247-263.
103. Spieth LE, Harnish JD, Lenders CM et al. 2000 A low-glycemic index diet in the treatment of pediatric obesity. Archives of Pediatrics and Adolescent Medicine 154, 947-951.
104. Stamets K, Taylor DS, Kunselman A et al. 2004 A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome. Fertility and Sterility 81, 630-637.
105. van Dam HA, van der Horst FG, Knoops L et al. 2005 Social support in diabetes: a systematic review of controlled intervention studies. Patient Education and Counselling 59, 1-12.
106. Wadden TA, Butryn ML 2003 Behavioral treatment of obesity. Endocrinology and Metabolism Clinics of North America 32, 981-1003.
107. Wadstrom C, Larsson L, Knutsson E et al. 1991 The effect of excessive weight loss on skeletal muscle in man. A study of obese patients following gastroplasty. European Journal of Surgery 157, 347-354.
108. Wahrenberg H, Ek I, Reynisdottir S et al. 1999 Divergent effects of weight reduction and oral anticonception treatment on adrenergic lipolysis regulation in obese women with the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 84, 2182-2187.
109. Wing RR, Phelan S 2005 Long-term weight loss maintenance. American Journal of Clinical Nutrition 82, 222S-225S.