메뉴 건너뛰기




Volumn 21, Issue 1, 2006, Pages 12-19

Phosphorylated Akt1 in human breast cancer measured by direct sandwich enzyme-linked immunosorbent assay: Correlation with clinicopathological features and tumor VEGF-signaling system component levels

Author keywords

Akt PKB; Breast cancer; ELISA; VEGF; VEGFR1; VEGFR2

Indexed keywords

ANTINEOPLASTIC AGENT; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN KINASE B; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 33646183911     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.5301/JBM.2008.4066     Document Type: Article
Times cited : (5)

References (48)
  • 1
    • 0037229714 scopus 로고    scopus 로고
    • Overexpression of AKT2/protein kinase B beta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
    • Arboleda MJ, Lyons JF, Kabbinavar FF, et al. Overexpression of AKT2/ protein kinase B beta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer Res 2003; 63: 196-206.
    • (2003) Cancer Res , vol.63 , pp. 196-206
    • Arboleda, M.J.1    Lyons, J.F.2    Kabbinavar, F.F.3
  • 2
    • 0035090385 scopus 로고    scopus 로고
    • Akt takes centre stage in cell-cycle deregulation
    • El-Deiry WS. Akt takes centre stage in cell-cycle deregulation. Nat Cell Biol 2001; 3: E71-3.
    • (2001) Nat Cell Biol , vol.3
    • El-Deiry, W.S.1
  • 3
    • 0037118575 scopus 로고    scopus 로고
    • AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
    • Bacus SS, Altomare DA, Lyass L, et al. AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival. Oncogene 2002; 21: 3532-40.
    • (2002) Oncogene , vol.21 , pp. 3532-3540
    • Bacus, S.S.1    Altomare, D.A.2    Lyass, L.3
  • 5
    • 0030904561 scopus 로고    scopus 로고
    • The Pi3kinase/Akt signalling pathway delivers an anti-apoptotic signal
    • Kennedy S, Wagner A, Conzen S, et al. The Pi3kinase/Akt signalling pathway delivers an anti-apoptotic signal. Genes Dev 1997; 11: 701-13.
    • (1997) Genes Dev , vol.11 , pp. 701-713
    • Kennedy, S.1    Wagner, A.2    Conzen, S.3
  • 6
    • 21644480047 scopus 로고    scopus 로고
    • Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells
    • Soderlund K, Perez-Tenorio G, Stal O. Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells. Int J Oncol 2005; 26: 25-32.
    • (2005) Int J Oncol , vol.26 , pp. 25-32
    • Soderlund, K.1    Perez-Tenorio, G.2    Stal, O.3
  • 7
    • 0035477438 scopus 로고    scopus 로고
    • Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway
    • Blancher C, Moore JW, Robertson N, Harris AL. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/ Akt signaling pathway. Cancer Res 2001; 61: 7349-55.
    • (2001) Cancer Res , vol.61 , pp. 7349-7355
    • Blancher, C.1    Moore, J.W.2    Robertson, N.3    Harris, A.L.4
  • 8
    • 7044234484 scopus 로고    scopus 로고
    • Different signalling pathways regulate VEGF and IL-8 expression in breast cancer: Implications for therapy
    • Chelouche-Lev D, Miller CP, Tellez C, Ruiz M, Bar-Eli M, Price JE. Different signalling pathways regulate VEGF and IL-8 expression in breast cancer: implications for therapy. Eur J Cancer 2004; 40: 2509-18.
    • (2004) Eur J Cancer , vol.40 , pp. 2509-2518
    • Chelouche-Lev, D.1    Miller, C.P.2    Tellez, C.3    Ruiz, M.4    Bar-Eli, M.5    Price, J.E.6
  • 9
    • 0037115522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
    • Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002; 62: 7203-6.
    • (2002) Cancer Res , vol.62 , pp. 7203-7206
    • Bachelder, R.E.1    Wendt, M.A.2    Mercurio, A.M.3
  • 10
    • 0034925637 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
    • Price DJ, Miralem T, Jiang S, Steinberg R, Avraham H. Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells. Cell Growth Differ 2001; 12: 129-35.
    • (2001) Cell Growth Differ , vol.12 , pp. 129-135
    • Price, D.J.1    Miralem, T.2    Jiang, S.3    Steinberg, R.4    Avraham, H.5
  • 11
    • 0034929216 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
    • Pidgeon GP, Barr MP, Harmey JH, Foley DA, Bouchier-Haves DJ. Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells. Br J Cancer 2001; 85: 273-8.
    • (2001) Br J Cancer , vol.85 , pp. 273-278
    • Pidgeon, G.P.1    Barr, M.P.2    Harmey, J.H.3    Foley, D.A.4    Bouchier-Haves, D.J.5
  • 12
    • 0037884924 scopus 로고    scopus 로고
    • Estradiol rapidly activates Akt via the ErbB2 signaling pathway
    • Stoica GE, Franke TF, Wellstein A, et al. Estradiol rapidly activates Akt via the ErbB2 signaling pathway. Mol Endocrinol 2003; 17: 818-30.
    • (2003) Mol Endocrinol , vol.17 , pp. 818-830
    • Stoica, G.E.1    Franke, T.F.2    Wellstein, A.3
  • 14
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
    • Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 2001; 276: 9817-24.
    • (2001) J Biol Chem , vol.276 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5    Nakshatri, H.6
  • 15
    • 0035881568 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
    • Sun M, Paciga JE, Feldman RI, et al. Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Res 2001; 61: 5985-91.
    • (2001) Cancer Res , vol.61 , pp. 5985-5991
    • Sun, M.1    Paciga, J.E.2    Feldman, R.I.3
  • 16
    • 0036633164 scopus 로고    scopus 로고
    • Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
    • Clark AS, West K, Streicher S, Dennis PA. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2002; 1: 707-17.
    • (2002) Mol Cancer Ther , vol.1 , pp. 707-717
    • Clark, A.S.1    West, K.2    Streicher, S.3    Dennis, P.A.4
  • 17
    • 0037945211 scopus 로고    scopus 로고
    • HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells
    • Knuefermann C, Lu Y, Liu B, et al. HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene 2003; 22: 3205-12.
    • (2003) Oncogene , vol.22 , pp. 3205-3212
    • Knuefermann, C.1    Lu, Y.2    Liu, B.3
  • 18
    • 0043163868 scopus 로고    scopus 로고
    • EGFR family signaling and its association with breast cancer development and resistance to chemotherapy
    • (Review)
    • Navolanic PM, Steelman LS, McCubrey JA. EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (Review). Int J Oncol 2003; 22: 237-52.
    • (2003) Int J Oncol , vol.22 , pp. 237-252
    • Navolanic, P.M.1    Steelman, L.S.2    McCubrey, J.A.3
  • 19
    • 16844382968 scopus 로고    scopus 로고
    • Signaling intricacies take center stage in cancer cells
    • Kumar R, Hung MC. Signaling intricacies take center stage in cancer cells. Cancer Res 2005; 65: 2511-5.
    • (2005) Cancer Res , vol.65 , pp. 2511-2515
    • Kumar, R.1    Hung, M.C.2
  • 20
    • 0037241504 scopus 로고    scopus 로고
    • Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer
    • Johnston SR, Head J, Pancholi S, et al. Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. Clin Cancer Res 2003; 9: 524-32S.
    • (2003) Clin Cancer Res , vol.9
    • Johnston, S.R.1    Head, J.2    Pancholi, S.3
  • 21
    • 0042399368 scopus 로고    scopus 로고
    • Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy
    • Liang K, Jin W, Knuefermann C, et al. Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy. Mol Cancer Ther 2003; 2: 353-60.
    • (2003) Mol Cancer Ther , vol.2 , pp. 353-360
    • Liang, K.1    Jin, W.2    Knuefermann, C.3
  • 22
    • 10744230387 scopus 로고    scopus 로고
    • Linking molecular diagnostics to molecular therapeutics: Targeting the PI3K pathway in breast cancer
    • Mills GB, Kohn E, Lu Y, et al. Linking molecular diagnostics to molecular therapeutics: targeting the PI3K pathway in breast cancer. Semin Oncol 2003; 30 (5 Suppl 16): 93-104.
    • (2003) Semin Oncol , vol.30 , Issue.5 SUPPL. 16 , pp. 93-104
    • Mills, G.B.1    Kohn, E.2    Lu, Y.3
  • 23
    • 0034742120 scopus 로고    scopus 로고
    • AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
    • Sun M, Wang G, Paciga JE, et al. AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol 2001; 159: 431-7.
    • (2001) Am J Pathol , vol.159 , pp. 431-437
    • Sun, M.1    Wang, G.2    Paciga, J.E.3
  • 24
    • 18244391514 scopus 로고    scopus 로고
    • Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
    • members of the Southeast Sweden Breast Cancer Group
    • Perez-Tenorio G, Stal O and members of the Southeast Sweden Breast Cancer Group. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br J Cancer 2002; 86: 540-5.
    • (2002) Br J Cancer , vol.86 , pp. 540-545
    • Perez-Tenorio, G.1    Stal, O.2
  • 25
    • 0029127042 scopus 로고
    • Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
    • Bellacosa A, de Feo D, Godwin AK, et al. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int J Cancer 1995; 64: 280-5.
    • (1995) Int J Cancer , vol.64 , pp. 280-285
    • Bellacosa, A.1    de Feo, D.2    Godwin, A.K.3
  • 26
    • 0038700565 scopus 로고    scopus 로고
    • Akt kinases in breast cancer and the results of adjuvant therapy
    • Stal O, Perez-Tenorio G, Akerberg L, et al. Akt kinases in breast cancer and the results of adjuvant therapy. Breast Cancer Res 2003; 5: R37-44.
    • (2003) Breast Cancer Res , vol.5
    • Stal, O.1    Perez-Tenorio, G.2    Akerberg, L.3
  • 27
    • 0034881622 scopus 로고    scopus 로고
    • AKT-1, -2, and -3 are expressed in both normal and tumor tissues of the lung, breast, prostate, and colon
    • Zinda MJ, Johnson MA, Paul JD, et al. AKT-1, -2, and -3 are expressed in both normal and tumor tissues of the lung, breast, prostate, and colon. Clin Cancer Res 2001; 7: 2475-9.
    • (2001) Clin Cancer Res , vol.7 , pp. 2475-2479
    • Zinda, M.J.1    Johnson, M.A.2    Paul, J.D.3
  • 28
    • 0033618371 scopus 로고    scopus 로고
    • Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
    • Nakatani K, Thompson DA, Barthel A, et al. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem 1999; 274: 21528-32.
    • (1999) J Biol Chem , vol.274 , pp. 21528-21532
    • Nakatani, K.1    Thompson, D.A.2    Barthel, A.3
  • 29
    • 6044223545 scopus 로고    scopus 로고
    • Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers
    • Zhou X, Tan M, Stone Hawthorne V, et al. Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res 2004; 10: 6779-88.
    • (2004) Clin Cancer Res , vol.10 , pp. 6779-6788
    • Zhou, X.1    Tan, M.2    Stone Hawthorne, V.3
  • 30
    • 18044373883 scopus 로고    scopus 로고
    • Activated Akt expression in breast cancer: Correlation with p53, Hdm2 and patient outcome
    • Vestey SB, Sen C, Calder CJ, Perks CM, Pignatelli M, Winters ZE. Activated Akt expression in breast cancer: correlation with p53, Hdm2 and patient outcome. Eur J Cancer 2005; 41: 1017-25.
    • (2005) Eur J Cancer , vol.41 , pp. 1017-1025
    • Vestey, S.B.1    Sen, C.2    Calder, C.J.3    Perks, C.M.4    Pignatelli, M.5    Winters, Z.E.6
  • 31
    • 4544231168 scopus 로고    scopus 로고
    • Prognostic relevance of activated Akt kinase in node-negative breast cancer: A clinicopathological study of 99 cases
    • Schmitz KJ, Otterbach F, Callies R, et al. Prognostic relevance of activated Akt kinase in node-negative breast cancer: a clinicopathological study of 99 cases. Mod Pathol 2004; 17: 15-21.
    • (2004) Mod Pathol , vol.17 , pp. 15-21
    • Schmitz, K.J.1    Otterbach, F.2    Callies, R.3
  • 32
    • 27144539046 scopus 로고    scopus 로고
    • High expression of focal adheson kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome
    • Schmitz KJ, Grabellus F, Callies R, et al. High expression of focal adheson kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome. Breast Cancer Res 2005; 7: R194-203.
    • (2005) Breast Cancer Res , vol.7
    • Schmitz, K.J.1    Grabellus, F.2    Callies, R.3
  • 33
    • 33644797510 scopus 로고    scopus 로고
    • Increased level of phosporylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2
    • Cicenas J, Urban P, Vuaroqueaux V, et al. Increased level of phosporylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2. Breast Cancer Res 2005; 7: R394-401.
    • (2005) Breast Cancer Res , vol.7
    • Cicenas, J.1    Urban, P.2    Vuaroqueaux, V.3
  • 34
    • 4544223402 scopus 로고    scopus 로고
    • The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome
    • Panigrahi AR, Pinder SE, Chan SY, Paish EC, Robertson JF, Ellis IO. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome. J Pathol 2004; 204: 93-100.
    • (2004) J Pathol , vol.204 , pp. 93-100
    • Panigrahi, A.R.1    Pinder, S.E.2    Chan, S.Y.3    Paish, E.C.4    Robertson, J.F.5    Ellis, I.O.6
  • 37
    • 0022604360 scopus 로고
    • Trepanobiopsy as a tool for the study of the influence of presurgical treatment on the steroid receptor status of advanced breast cancer
    • Bassalyk LS, Koposova TL, Muravyeva NI, et al. Trepanobiopsy as a tool for the study of the influence of presurgical treatment on the steroid receptor status of advanced breast cancer. Neoplasma 1986; 33: 245-50.
    • (1986) Neoplasma , vol.33 , pp. 245-250
    • Bassalyk, L.S.1    Koposova, T.L.2    Muravyeva, N.I.3
  • 38
    • 0032510109 scopus 로고    scopus 로고
    • Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes
    • Amundadottirl L, Leder P. Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes. Oncogene 1998; 16: 737-46.
    • (1998) Oncogene , vol.16 , pp. 737-746
    • Amundadottirl, L.1    Leder, P.2
  • 39
    • 2342527930 scopus 로고    scopus 로고
    • Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis, but suppresses tumor invasion
    • Hutchinson JN, Jin J, Cardiff RD, Woodgett JR, Muller WJ. Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis, but suppresses tumor invasion. Cancer Res 2004; 64: 3171-8.
    • (2004) Cancer Res , vol.64 , pp. 3171-3178
    • Hutchinson, J.N.1    Jin, J.2    Cardiff, R.D.3    Woodgett, J.R.4    Muller, W.J.5
  • 40
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000; 407: 538-41.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 41
    • 0037385522 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt /mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer
    • Cui X, Zhang P, Deng W, et al. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer. Mol Endocrinol 2003; 17: 575-88.
    • (2003) Mol Endocrinol , vol.17 , pp. 575-588
    • Cui, X.1    Zhang, P.2    Deng, W.3
  • 42
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005; 307: 1098-101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 43
    • 12544250381 scopus 로고    scopus 로고
    • Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signalling
    • Le XF, Lammayot A, Gold D, et al. Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signalling. J Biol Chem 2005; 280: 2092-104.
    • (2005) J Biol Chem , vol.280 , pp. 2092-2104
    • Le, X.F.1    Lammayot, A.2    Gold, D.3
  • 44
    • 22844439340 scopus 로고    scopus 로고
    • HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27(Kip1) via multiple signaling pathways
    • Le XF, Pruefer F, Bast RC, Jr. HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27(Kip1) via multiple signaling pathways. Cell Cycle 2005; 4: 87-95.
    • (2005) Cell Cycle , vol.4 , pp. 87-95
    • Le, X.F.1    Pruefer, F.2    Bast Jr., R.C.3
  • 45
    • 85039349127 scopus 로고    scopus 로고
    • Coordinate activation of Akt/PKB and VEGF signaling pathways in tamoxifen-resistant breast cancer cells
    • Fifteenth International Congress on Anti-cancer Chemotherapy. Paris, France, Feb 9th-12th
    • Scherbakov AM, Onopchenko OV, Gershtein ES, Krasil'nikov MA. Coordinate activation of Akt/PKB and VEGF signaling pathways in tamoxifen-resistant breast cancer cells. Fifteenth International Congress on Anti-cancer Chemotherapy. Paris, France, Feb 9th-12th 2004: 223.
    • (2004) , pp. 223
    • Scherbakov, A.M.1    Onopchenko, O.V.2    Gershtein, E.S.3    Krasil'nikov, M.A.4
  • 46
    • 0036497957 scopus 로고    scopus 로고
    • Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breast cancer
    • Toi M, Bando H, Ogawa T, Muta M, Hornig C, Weich HA. Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breast cancer. Int J Cancer 2002; 98: 14-8.
    • (2002) Int J Cancer , vol.98 , pp. 14-18
    • Toi, M.1    Bando, H.2    Ogawa, T.3    Muta, M.4    Hornig, C.5    Weich, H.A.6
  • 47
    • 6444221837 scopus 로고    scopus 로고
    • Circulating levels of VEGF-A, VEGF-D and soluble VEGF-A receptor (sFlt-1) in human breast cancer
    • Hoar FJ, Lip GY, Belgore F, Stonelake PS. Circulating levels of VEGF-A, VEGF-D and soluble VEGF-A receptor (sFlt-1) in human breast cancer. Int J Biol Markers 2004; 19: 229-35.
    • (2004) Int J Biol Markers , vol.19 , pp. 229-235
    • Hoar, F.J.1    Lip, G.Y.2    Belgore, F.3    Stonelake, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.