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Volumn 6, Issue 3 C, 2006, Pages

Diagnosis and treatment selection in elderly patients with epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTINEOPLASTIC AGENT; CARBAMAZEPINE; CARDIOVASCULAR AGENT; CYTOCHROME P450 ISOENZYME; DIURETIC AGENT; DRUG METABOLITE; ETHOSUXIMIDE; ETIRACETAM; FELBAMATE; FOSPHENYTOIN SODIUM; GABAPENTIN; LAMOTRIGINE; LIVER ENZYME; NEW DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; PREGABALIN; PRIMIDONE; PROTEINASE INHIBITOR; PSYCHOTROPIC AGENT; TIAGABINE; TOPIRAMATE; UNINDEXED DRUG; VALPROIC ACID; ZONISAMIDE;

EID: 33645997723     PISSN: 15303004     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (106)
  • 1
    • 0027152087 scopus 로고
    • Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota, 1935-1984
    • Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota, 1935-1984. Epilepsia. 1993;34:453-468.
    • (1993) Epilepsia , vol.34 , pp. 453-468
    • Hauser, W.A.1    Annegers, J.F.2    Kurland, L.T.3
  • 2
    • 0028915209 scopus 로고
    • Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984
    • Annegers JF, Hauser WA, Lee JR, Rocca WA. Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984. Epilepsia. 1995;36:327-333.
    • (1995) Epilepsia , vol.36 , pp. 327-333
    • Annegers, J.F.1    Hauser, W.A.2    Lee, J.R.3    Rocca, W.A.4
  • 3
    • 0003884696 scopus 로고    scopus 로고
    • Washington, DC: US Dept of Health and Human Services
    • US Dept of Health and Human Services, Administration on Aging. A Profile of Older Americans: 2000. Washington, DC: US Dept of Health and Human Services; 2000.
    • (2000) A Profile of Older Americans: 2000
  • 4
    • 0038462269 scopus 로고    scopus 로고
    • Antiepileptic drug use in nursing home admissions
    • Garrard J, Harms S, Hardie N, et al. Antiepileptic drug use in nursing home admissions. Ann Neurol. 2003;54:75-85.
    • (2003) Ann Neurol , vol.54 , pp. 75-85
    • Garrard, J.1    Harms, S.2    Hardie, N.3
  • 5
    • 20444407159 scopus 로고    scopus 로고
    • New onset geriatric epilepsy: A randomized study of gabapentin, lamotrigine, and carbamazepine
    • Rowan AJ, Ramsay RE, Collins JF, et al. New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. Neurology. 2005;64:1868-1873.
    • (2005) Neurology , vol.64 , pp. 1868-1873
    • Rowan, A.J.1    Ramsay, R.E.2    Collins, J.F.3
  • 6
    • 0030805745 scopus 로고    scopus 로고
    • A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy
    • Bill PA, Vigonius U, Pohlmann H, et al. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy. Epilepsy Res. 1997;27:195-204.
    • (1997) Epilepsy Res , vol.27 , pp. 195-204
    • Bill, P.A.1    Vigonius, U.2    Pohlmann, H.3
  • 7
    • 0343247768 scopus 로고    scopus 로고
    • A double-blind controlled tria: Oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy
    • Christe W, Kramer G, Vigonius U, et al. A double-blind controlled tria: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. Epilepsy Res. 1997;26:451-460.
    • (1997) Epilepsy Res , vol.26 , pp. 451-460
    • Christe, W.1    Kramer, G.2    Vigonius, U.3
  • 8
    • 0030054378 scopus 로고    scopus 로고
    • Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures
    • Mattson RH, Cramer JA, Collins JF, et al. Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures. Neurology. 1996;47:68-76.
    • (1996) Neurology , vol.47 , pp. 68-76
    • Mattson, R.H.1    Cramer, J.A.2    Collins, J.F.3
  • 10
    • 0141761520 scopus 로고    scopus 로고
    • Seizures in elderly patients with dementia: Epidemiology and management
    • Mendez MF, Lim GTH. Seizures in elderly patients with dementia: epidemiology and management. Drugs Aging. 2003;20:791-803.
    • (2003) Drugs Aging , vol.20 , pp. 791-803
    • Mendez, M.F.1    Lim, G.T.H.2
  • 13
    • 1542346294 scopus 로고    scopus 로고
    • Special considerations in treating the elderly patient with epilepsy
    • Ramsay RE, Rowan AJ, Pryor FM. Special considerations in treating the elderly patient with epilepsy. Neurology. 2004;62(5, suppl 2):S24-S29.
    • (2004) Neurology , vol.62 , Issue.5 SUPPL. 2
    • Ramsay, R.E.1    Rowan, A.J.2    Pryor, F.M.3
  • 14
    • 0021887675 scopus 로고
    • Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures
    • Mattson RH, Cramer JA, Collins JF, et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med. 1985;313:145-151.
    • (1985) N Engl J Med , vol.313 , pp. 145-151
    • Mattson, R.H.1    Cramer, J.A.2    Collins, J.F.3
  • 15
    • 0026794763 scopus 로고
    • A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults
    • Mattson RH, Cramer JA, Collins JF, et al. A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. N Engl J Med. 1992;327:765-771.
    • (1992) N Engl J Med , vol.327 , pp. 765-771
    • Mattson, R.H.1    Cramer, J.A.2    Collins, J.F.3
  • 16
    • 0032877268 scopus 로고    scopus 로고
    • Multicenter, double-blind, randomized comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy
    • Brodie MJ, Overstall PW, Giorgi L, et al. Multicenter, double-blind, randomized comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. Epilepsy Res. 1999;37:81-87.
    • (1999) Epilepsy Res , vol.37 , pp. 81-87
    • Brodie, M.J.1    Overstall, P.W.2    Giorgi, L.3
  • 17
    • 0033918752 scopus 로고    scopus 로고
    • Efficacy of gabapentin as adjunctive therapy in a large, multicenter study
    • Morrell MJ, McLean MJ, Willmore LJ, et al. Efficacy of gabapentin as adjunctive therapy in a large, multicenter study. Seizure. 2000;9:241-248.
    • (2000) Seizure , vol.9 , pp. 241-248
    • Morrell, M.J.1    McLean, M.J.2    Willmore, L.J.3
  • 18
    • 0038094419 scopus 로고    scopus 로고
    • The KEEPER trial: Levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study
    • Morrell MJ, Leppik I, French J, et al. The KEEPER trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study. Epilepsy Res. 2003;54:153-161.
    • (2003) Epilepsy Res , vol.54 , pp. 153-161
    • Morrell, M.J.1    Leppik, I.2    French, J.3
  • 19
    • 0347418143 scopus 로고    scopus 로고
    • Use of levetiracetam in a population aged 65 years and older: A subset analysis of the KEEPER trial
    • Ferrendelli JA, French J, Leppik I, et al. Use of levetiracetam in a population aged 65 years and older: a subset analysis of the KEEPER trial. Epilepsy Behav. 2003;4:702-709.
    • (2003) Epilepsy Behav , vol.4 , pp. 702-709
    • Ferrendelli, J.A.1    French, J.2    Leppik, I.3
  • 20
    • 11144356543 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2004;62:1252-1260.
    • (2004) Neurology , vol.62 , pp. 1252-1260
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 21
    • 11144353969 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2004;62:1261-1273.
    • (2004) Neurology , vol.62 , pp. 1261-1273
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 22
    • 0036445260 scopus 로고    scopus 로고
    • A workshop on antiepileptic drug monotherapy indications
    • French JA, Schachter S. A workshop on antiepileptic drug monotherapy indications. Epilepsia. 2002;43(suppl 10):3-27.
    • (2002) Epilepsia , vol.43 , Issue.SUPPL. 10 , pp. 3-27
    • French, J.A.1    Schachter, S.2
  • 23
    • 0032872770 scopus 로고    scopus 로고
    • Differential cognitive effects of carbamazepine and gabapentin
    • Meador KJ, Loring DW, Ray PG, et al. Differential cognitive effects of carbamazepine and gabapentin. Epilepsia. 1999;40:1279-1285.
    • (1999) Epilepsia , vol.40 , pp. 1279-1285
    • Meador, K.J.1    Loring, D.W.2    Ray, P.G.3
  • 24
    • 0035826962 scopus 로고    scopus 로고
    • Differential cognitive and behaviora effects of carbamazepine and lamotrigine
    • Meador KJ, Loring DW, Ray PG, et al. Differential cognitive and behaviora effects of carbamazepine and lamotrigine. Neurology. 2001;56:1177-1182.
    • (2001) Neurology , vol.56 , pp. 1177-1182
    • Meador, K.J.1    Loring, D.W.2    Ray, P.G.3
  • 26
    • 7044241281 scopus 로고    scopus 로고
    • Clinical, cognitive, and neurophysiologic correlates of short-term treatment with carbamazepine, oxcarbazepine, and levetiracetam in healthy volunteers
    • Mecarelli O, Vicenzini E, Pulitano P, et al. Clinical, cognitive, and neurophysiologic correlates of short-term treatment with carbamazepine, oxcarbazepine, and levetiracetam in healthy volunteers. Ann Pharmacother. 2004;38:1816-1822.
    • (2004) Ann Pharmacother , vol.38 , pp. 1816-1822
    • Mecarelli, O.1    Vicenzini, E.2    Pulitano, P.3
  • 27
    • 33646009917 scopus 로고    scopus 로고
    • Predictors of cognitive side effects in patients with epilepsy
    • Hirsch L, Weintraub D, Spencer H, et al. Predictors of cognitive side effects in patients with epilepsy. Epilepsia. 2004;45(supp 7):102.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 102
    • Hirsch, L.1    Weintraub, D.2    Spencer, H.3
  • 28
    • 0031670028 scopus 로고    scopus 로고
    • Antiepileptic drug use in nursing home residents: Effect of age, gender, and comedication on patterns of use
    • Lackner TE, Cloyd JC, Thomas LW, Leppik IE. Antiepileptic drug use in nursing home residents: effect of age, gender, and comedication on patterns of use. Epilepsia. 1998;39:1083-1087.
    • (1998) Epilepsia , vol.39 , pp. 1083-1087
    • Lackner, T.E.1    Cloyd, J.C.2    Thomas, L.W.3    Leppik, I.E.4
  • 29
    • 0028472887 scopus 로고
    • Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics
    • Cloyd JC, Lackner TE, Leppik IE. Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics. Arch Fam Med. 1994;3:589-598.
    • (1994) Arch Fam Med , vol.3 , pp. 589-598
    • Cloyd, J.C.1    Lackner, T.E.2    Leppik, I.E.3
  • 30
    • 0242324682 scopus 로고    scopus 로고
    • Epilepsy in the elderly
    • Levy RH, Mattson RD, Meldrum BS, Perucca E, eds. Philadelphia, Pa: Lippincott Williams & Wilkens
    • Leppik IE, Cloyd JC. Epilepsy in the elderly. In: Levy RH, Mattson RD, Meldrum BS, Perucca E, eds. Antiepileptic Drugs. Philadelphia, Pa: Lippincott Williams & Wilkens; 2002:149-158.
    • (2002) Antiepileptic Drugs , pp. 149-158
    • Leppik, I.E.1    Cloyd, J.C.2
  • 31
    • 9644268255 scopus 로고    scopus 로고
    • Valproic acid doses, concentrations, and clearances in elderly nursing home residents
    • Birnbaum AK, Hardie NA, Conway JM, et al. Valproic acid doses, concentrations, and clearances in elderly nursing home residents. Epilepsy Res. 2004;62:157-162.
    • (2004) Epilepsy Res , vol.62 , pp. 157-162
    • Birnbaum, A.K.1    Hardie, N.A.2    Conway, J.M.3
  • 33
    • 0031667351 scopus 로고    scopus 로고
    • An evaluation of antiepileptic drug therapy in nursing facilities
    • Schachter SC, Cramer GW, Thompson GD, et al. An evaluation of antiepileptic drug therapy in nursing facilities. J Am Geriatr Soc. 1998;46:1137-1141.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 1137-1141
    • Schachter, S.C.1    Cramer, G.W.2    Thompson, G.D.3
  • 34
    • 0002341483 scopus 로고    scopus 로고
    • Commonly used antiepileptic drugs: Age-related pharmacokinetics
    • Rowan AJ, Ramsay RE, eds. Boston, Mass: Butterworth-Heinemann
    • Cloyd J. Commonly used antiepileptic drugs: age-related pharmacokinetics. In: Rowan AJ, Ramsay RE, eds. Seizures and Epilepsy in the Elderly. Boston, Mass: Butterworth-Heinemann; 1997:219-228.
    • (1997) Seizures and Epilepsy in the Elderly , pp. 219-228
    • Cloyd, J.1
  • 35
    • 0037465463 scopus 로고    scopus 로고
    • Variability of total phenytoin serum concentrations within elderly nursing home residents
    • Birnbaum A, Hardie NA, Leppik IE, et al. Variability of total phenytoin serum concentrations within elderly nursing home residents. Neurology. 2003;60:555-559.
    • (2003) Neurology , vol.60 , pp. 555-559
    • Birnbaum, A.1    Hardie, N.A.2    Leppik, I.E.3
  • 36
    • 0038714895 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs
    • Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs. Lancet Neurol. 2003;2:473-481.
    • (2003) Lancet Neurol , vol.2 , pp. 473-481
    • Patsalos, P.N.1    Perucca, E.2
  • 37
    • 0038196961 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: General features and interactions between antiepileptic drugs
    • Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. Lancet Neurol. 2003;2:347-356.
    • (2003) Lancet Neurol , vol.2 , pp. 347-356
    • Patsalos, P.N.1    Perucca, E.2
  • 38
    • 1542615066 scopus 로고    scopus 로고
    • Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy
    • Pugh MJ, Cramer J, Knoefel J, et al. Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy. J Am Geriatr Soc. 2004;52:417-422.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 417-422
    • Pugh, M.J.1    Cramer, J.2    Knoefel, J.3
  • 39
    • 0028294002 scopus 로고
    • Oxcarbazepine: Pharmacokinetic interactions and their clinical relevance
    • Baruzzi A, Albani F, Riva R. Oxcarbazepine: pharmacokinetic interactions and their clinical relevance. Epilepsia. 1994;35(suppl 3):S14-S19.
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 3
    • Baruzzi, A.1    Albani, F.2    Riva, R.3
  • 40
    • 0024324306 scopus 로고
    • Risk of age-related fractures in patients with unprovoked seizures
    • Annegers JF, Melton LJ 3rd, Sun CA, Hauser WA. Risk of age-related fractures in patients with unprovoked seizures. Epilepsia. 1989;30:348-355.
    • (1989) Epilepsia , vol.30 , pp. 348-355
    • Annegers, J.F.1    Melton III, L.J.2    Sun, C.A.3    Hauser, W.A.4
  • 41
    • 33644698109 scopus 로고    scopus 로고
    • Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: Prospective observational cohort study
    • Epub Nov 18
    • Roche JJ, Wenn RT, Sahota O, Moran CG. Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ. Epub 2005 Nov 18.
    • (2005) BMJ
    • Roche, J.J.1    Wenn, R.T.2    Sahota, O.3    Moran, C.G.4
  • 42
    • 8844283596 scopus 로고    scopus 로고
    • The association between antiepileptic drugs and bone disease
    • Pack A. The association between antiepileptic drugs and bone disease. Epilepsy Curr. 2003;3:91-95.
    • (2003) Epilepsy Curr , vol.3 , pp. 91-95
    • Pack, A.1
  • 43
    • 0036094249 scopus 로고    scopus 로고
    • Antiepileptic drug-induced bone loss in young male patients who have seizures
    • Andress DL, Ozuna J, Tirschwell D, et al. Antiepileptic drug-induced bone loss in young male patients who have seizures. Arch Neurol. 2002;59:781-786.
    • (2002) Arch Neurol , vol.59 , pp. 781-786
    • Andress, D.L.1    Ozuna, J.2    Tirschwell, D.3
  • 44
    • 13144282677 scopus 로고    scopus 로고
    • Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy
    • Pack AM, Morrell MJ, Marcus R, et al. Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy. Ann Neurol. 2005;57:252-257.
    • (2005) Ann Neurol , vol.57 , pp. 252-257
    • Pack, A.M.1    Morrell, M.J.2    Marcus, R.3
  • 45
    • 27644560546 scopus 로고    scopus 로고
    • Effect of antiepileptic medication on bone mineral measures
    • Petty SJ, Paton LM, O'Brien TJ, et al. Effect of antiepileptic medication on bone mineral measures. Neurology. 2005;65:1358-1365.
    • (2005) Neurology , vol.65 , pp. 1358-1365
    • Petty, S.J.1    Paton, L.M.2    O'Brien, T.J.3
  • 46
    • 33645973156 scopus 로고    scopus 로고
    • Bone mineral density changes after one year of antiepileptic drug treatment in women with epilepsy
    • Pack AM, Morrell MJ, Flaster E, et al. Bone mineral density changes after one year of antiepileptic drug treatment in women with epilepsy. Epilepsia. 2004;45(suppl 7):187.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 187
    • Pack, A.M.1    Morrell, M.J.2    Flaster, E.3
  • 47
    • 33646010545 scopus 로고    scopus 로고
    • Occurrence of osteoporosis and risk factors in patients with epilepsy
    • Morganroth LP, Gidal BE, Nemire RE, et al. Occurrence of osteoporosis and risk factors in patients with epilepsy. Epilepsia. 2004;45(suppl 7):264.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 264
    • Morganroth, L.P.1    Gidal, B.E.2    Nemire, R.E.3
  • 48
    • 2942562767 scopus 로고    scopus 로고
    • Antiepileptic drug use increases rates of bone loss in older women: A prospective study
    • Ensrud KE, Walczak TS, Blackwell T, et al. Antiepileptic drug use increases rates of bone loss in older women: a prospective study. Neurology. 2004;62:2051-2057.
    • (2004) Neurology , vol.62 , pp. 2051-2057
    • Ensrud, K.E.1    Walczak, T.S.2    Blackwell, T.3
  • 49
    • 0032882451 scopus 로고    scopus 로고
    • Bone density and antiepileptic drugs: A case controlled study
    • Stephen LJ, McLellan AR, Harrison JH, et al. Bone density and antiepileptic drugs: a case controlled study. Seizure. 1999;8:339-342.
    • (1999) Seizure , vol.8 , pp. 339-342
    • Stephen, L.J.1    McLellan, A.R.2    Harrison, J.H.3
  • 50
    • 0037716719 scopus 로고    scopus 로고
    • Effects of chronic administration of zonisamide, an antiepileptic drug, an bone mineral density and their prevention with alfacalcidol in growing rats
    • Takahashi A, Onodera K, Kamei J, et al. Effects of chronic administration of zonisamide, an antiepileptic drug, an bone mineral density and their prevention with alfacalcidol in growing rats. J Pharmacol Sci. 2003;91:313-318.
    • (2003) J Pharmacol Sci , vol.91 , pp. 313-318
    • Takahashi, A.1    Onodera, K.2    Kamei, J.3
  • 54
    • 0028456066 scopus 로고
    • Clinical pharmacokinetics of gabapentin
    • McLean MJ. Clinical pharmacokinetics of gabapentin. Neurology. 1994;44(6, suppl 5):S17-S22.
    • (1994) Neurology , vol.44 , Issue.6 SUPPL. 5
    • McLean, M.J.1
  • 55
    • 33645684830 scopus 로고    scopus 로고
    • New York, NY: Parke-Davis Div of Pfizer Inc
    • Neurontin [prescribing information]. New York, NY: Parke-Davis Div of Pfizer Inc; 2004.
    • (2004) Neurontin [Prescribing Information]
  • 56
    • 0035144393 scopus 로고    scopus 로고
    • Relative bioavailability of lamotrigine chewable dispersible tablets administered rectally
    • Birnbaum AK, Kriel RL, Im Y, Remmel RP. Relative bioavailability of lamotrigine chewable dispersible tablets administered rectally. Pharmacotherapy. 2001;21:158-162.
    • (2001) Pharmacotherapy , vol.21 , pp. 158-162
    • Birnbaum, A.K.1    Kriel, R.L.2    Im, Y.3    Remmel, R.P.4
  • 57
    • 0023475125 scopus 로고
    • Lamotrigine, a new anticonvulsant: Pharmacokinetics in normal humans
    • Cohen AF, Land GS, Breimer DD, et al. Lamotrigine, a new anticonvulsant: pharmacokinetics in normal humans. Clin Pharmacol Ther. 1987;42:535-541.
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 535-541
    • Cohen, A.F.1    Land, G.S.2    Breimer, D.D.3
  • 58
    • 0029011113 scopus 로고
    • Lamotrigine
    • Messenheimer JA. Lamotrigine. Epilepsia. 1995;36(suppl 2):S87-S94.
    • (1995) Epilepsia , vol.36 , Issue.SUPPL. 2
    • Messenheimer, J.A.1
  • 59
    • 0345598116 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of 14C-levetiracetam, a new antiepileptic agent, in healthy volunteers
    • Strolin Benedetti M, Whomsley R, Nicolas JM, et al. Pharmacokinetics and metabolism of 14C-levetiracetam, a new antiepileptic agent, in healthy volunteers. Eur J Clin Pharmacol. 2003;59:621-630.
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 621-630
    • Strolin Benedetti, M.1    Whomsley, R.2    Nicolas, J.M.3
  • 60
    • 0242552652 scopus 로고    scopus 로고
    • Levetiracetam: Relative bioavailability and bioequivalence of a 10% oral solution (750 mg) and 750-mg tablets
    • Coupez R, Straetemans R, Sehga G, et al. Levetiracetam: relative bioavailability and bioequivalence of a 10% oral solution (750 mg) and 750-mg tablets. J Clin Pharmacol. 2003;43:1370-1376.
    • (2003) J Clin Pharmacol , vol.43 , pp. 1370-1376
    • Coupez, R.1    Straetemans, R.2    Sehga, G.3
  • 61
    • 0028258322 scopus 로고
    • Clinical pharmacology and pharmacokinetics of oxcarbazepine
    • Lloyd P, Flesch G, Dieterle W. Clinical pharmacology and pharmacokinetics of oxcarbazepine. Epilepsia. 1994;35(suppl 3):S10-S13.
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 3
    • Lloyd, P.1    Flesch, G.2    Dieterle, W.3
  • 62
    • 33645986049 scopus 로고    scopus 로고
    • East Hanover, NJ: Novartis Pharmaceuticals Corp; March
    • Trileptal [prescribing information]. East Hanover, NJ: Novartis Pharmaceuticals Corp; March 2004.
    • (2004) Trileptal [Prescribing Information]
  • 63
    • 0024424209 scopus 로고
    • Pharmacokinetics and clinical use of parenteral phenytoin, phenobarbital, and paraldehyde
    • Ramsay RE. Pharmacokinetics and clinical use of parenteral phenytoin, phenobarbital, and paraldehyde. Epilepsia. 1989;30(suppl 2):S1-S3.
    • (1989) Epilepsia , vol.30 , Issue.SUPPL. 2
    • Ramsay, R.E.1
  • 64
    • 0002392095 scopus 로고    scopus 로고
    • Pregabalin single-dose kinetics and safety/tolerance in healthy subjects after oral administration of pregabalin solution or capsule doses
    • Busch JA, Strand JC, Posvar EL, et al. Pregabalin single-dose kinetics and safety/tolerance in healthy subjects after oral administration of pregabalin solution or capsule doses. Epilepsia. 1998;39(suppl 6):S58.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6
    • Busch, J.A.1    Strand, J.C.2    Posvar, E.L.3
  • 67
    • 0029804193 scopus 로고    scopus 로고
    • Single-dose pharmacokinetics and effect of food on the bioavailability of topiramate, a novel antiepileptic drug
    • Doose DR, Walker SA, Gisclon LG, Nayak RK. Single-dose pharmacokinetics and effect of food on the bioavailability of topiramate, a novel antiepileptic drug. J Clin Pharmacol. 1996;36:884-891.
    • (1996) J Clin Pharmacol , vol.36 , pp. 884-891
    • Doose, D.R.1    Walker, S.A.2    Gisclon, L.G.3    Nayak, R.K.4
  • 68
    • 33645960892 scopus 로고    scopus 로고
    • Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc; June
    • Topamax [prescribing information]. Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc; June 2004.
    • (2004) Topamax [Prescribing Information]
  • 69
    • 0028045747 scopus 로고
    • Valproic acid: A reappraisal of its pharmacologica properties and clinical efficacy in epilepsy
    • Davis R, Peters DH, McTavish D. Valproic acid: a reappraisal of its pharmacologica properties and clinical efficacy in epilepsy. Drugs. 1994;47:332-372.
    • (1994) Drugs , vol.47 , pp. 332-372
    • Davis, R.1    Peters, D.H.2    McTavish, D.3
  • 70
    • 33646002568 scopus 로고    scopus 로고
    • North Chicago, Ill: Abbott Laboratories; November
    • Depakote ER [prescribing information]. North Chicago, Ill: Abbott Laboratories; November 2003.
    • (2003) Depakote ER [Prescribing Information]
  • 72
    • 0031883882 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of zonisamide, an antiepileptic agent for treatment of refractory complex partial seizures
    • Kochak GM, Page JG, Buchanan RA, et al. Steady-state pharmacokinetics of zonisamide, an antiepileptic agent for treatment of refractory complex partial seizures. J Clin Pharmacol. 1998;38:166-171.
    • (1998) J Clin Pharmacol , vol.38 , pp. 166-171
    • Kochak, G.M.1    Page, J.G.2    Buchanan, R.A.3
  • 73
    • 33645985715 scopus 로고    scopus 로고
    • San Diego, Calif: Elan Pharmaceuticals
    • Zonegran [prescribing information]. San Diego, Calif: Elan Pharmaceuticals; 2004.
    • (2004) Zonegran [Prescribing Information]
  • 74
    • 0033921605 scopus 로고    scopus 로고
    • Factors associated with antiepileptic drug use among elderly nursing home residents
    • Garrard J, Cloyd J, Gross C, et al. Factors associated with antiepileptic drug use among elderly nursing home residents. J Gerontol A Biol Sci Med Sci. 2000;55:M384-M392.
    • (2000) J Gerontol A Biol Sci Med Sci , vol.55
    • Garrard, J.1    Cloyd, J.2    Gross, C.3
  • 76
    • 0002702004 scopus 로고    scopus 로고
    • Valproate
    • Engel J Jr, Pedley TA, eds. Philadelphia, Pa: Lippincott-Raven Publishers
    • Rowan AJ. Valproate. In: Engel J Jr, Pedley TA, eds. Epilepsy: A Comprehensive Textbook. Philadelphia, Pa: Lippincott-Raven Publishers; 1997:1599-1607.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 1599-1607
    • Rowan, A.J.1
  • 77
    • 0029925182 scopus 로고    scopus 로고
    • Valproic acid hepatic fatalities. III. U.S. experience since 1986
    • Bryant AE III, Dreifuss FE. Valproic acid hepatic fatalities. III. U.S. experience since 1986. Neurology. 1996;46:465-469.
    • (1996) Neurology , vol.46 , pp. 465-469
    • Bryant III, A.E.1    Dreifuss, F.E.2
  • 78
    • 0031024282 scopus 로고    scopus 로고
    • Safety and efficacy of divalproex sodium monotherapy in partial epilepsy: A double-blind, concentration-response design clinical trial
    • Beydoun A, Sackellares JC, Shu V, et al. Safety and efficacy of divalproex sodium monotherapy in partial epilepsy: a double-blind, concentration-response design clinical trial. Neurology. 1997;48:182-188.
    • (1997) Neurology , vol.48 , pp. 182-188
    • Beydoun, A.1    Sackellares, J.C.2    Shu, V.3
  • 79
    • 33645973593 scopus 로고    scopus 로고
    • Valproic acid does not cause weight gain in the elderly
    • Tettenborn B, Atefy R. Valproic acid does not cause weight gain in the elderly. Epilepsia. 2004;45(suppl 7):315.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 315
    • Tettenborn, B.1    Atefy, R.2
  • 80
    • 0037282719 scopus 로고    scopus 로고
    • Drug treatment of epilepsy in elderly people: Focus on valproic acid
    • Stephen LJ. Drug treatment of epilepsy in elderly people: focus on valproic acid. Drugs Aging. 2003;20:141-152.
    • (2003) Drugs Aging , vol.20 , pp. 141-152
    • Stephen, L.J.1
  • 81
    • 16844370521 scopus 로고    scopus 로고
    • Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics
    • Mockenhaupt M, Messenheimer J, Tennis P, Schlingmann J. Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. Neurology. 2005;64:1134-1138.
    • (2005) Neurology , vol.64 , pp. 1134-1138
    • Mockenhaupt, M.1    Messenheimer, J.2    Tennis, P.3    Schlingmann, J.4
  • 82
    • 0023574269 scopus 로고
    • Lamotrigine: Single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy
    • Jawad S, Yuen WC, Peck AW, et al. Lamotrigine: single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy. Epilepsy Res. 1987;1:194-201.
    • (1987) Epilepsy Res , vol.1 , pp. 194-201
    • Jawad, S.1    Yuen, W.C.2    Peck, A.W.3
  • 83
    • 32944469484 scopus 로고    scopus 로고
    • Evidence-based treatment of idiopathic generalized epilepsies with new antiepileptic drugs
    • Bergey GK. Evidence-based treatment of idiopathic generalized epilepsies with new antiepileptic drugs. Epilepsia. 2005;46(suppl 9):161-168.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 9 , pp. 161-168
    • Bergey, G.K.1
  • 84
    • 0347985301 scopus 로고    scopus 로고
    • Pregabalin add-on treatment: A randomized, double-blind, placebo-controlled, dose-response study in adults with partial seizures
    • Arroyo S, Anhut H, Kugler AR, et al. Pregabalin add-on treatment: a randomized, double-blind, placebo-controlled, dose-response study in adults with partial seizures. Epilepsia. 2004;45:20-27.
    • (2004) Epilepsia , vol.45 , pp. 20-27
    • Arroyo, S.1    Anhut, H.2    Kugler, A.R.3
  • 85
    • 0038476172 scopus 로고    scopus 로고
    • Dose-response trial of pregabalin adjunctive therapy in patients with partial seizures
    • French JA, Kugler AR, Robbins JL, et al. Dose-response trial of pregabalin adjunctive therapy in patients with partial seizures. Neurology. 2003;60:1631-1637.
    • (2003) Neurology , vol.60 , pp. 1631-1637
    • French, J.A.1    Kugler, A.R.2    Robbins, J.L.3
  • 86
    • 5344249471 scopus 로고    scopus 로고
    • Pregabalin pharmacology and its relevance to clinical practice
    • Ben-Menachem E. Pregabalin pharmacology and its relevance to clinical practice. Epilepsia. 2004;45(suppl 6):13-18.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 6 , pp. 13-18
    • Ben-Menachem, E.1
  • 87
    • 3843088696 scopus 로고    scopus 로고
    • Pregabalin for the treatment of painful diabetic peripheral neuropathy: A double-blind, placebo-controlled trial
    • Rosenstock J, Tuchman M, La Moreaux L, Sharma U. Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial. Pain. 2004;110:628-638.
    • (2004) Pain , vol.110 , pp. 628-638
    • Rosenstock, J.1    Tuchman, M.2    La Moreaux, L.3    Sharma, U.4
  • 88
    • 19444362218 scopus 로고    scopus 로고
    • Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomized, double-blind, multicentre, placebo-controlled trial of flexible-and fixed-dose regimens
    • Freynhagen R, Strojek K, Griesing T, et al. Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomized, double-blind, multicentre, placebo-controlled trial of flexible-and fixed-dose regimens. Pain. 2005;115:254-263.
    • (2005) Pain , vol.115 , pp. 254-263
    • Freynhagen, R.1    Strojek, K.2    Griesing, T.3
  • 89
    • 0037461323 scopus 로고    scopus 로고
    • Pregabalin for the treatment of postherpetic neuralgia: A randomized, placebo-controlled trial
    • Dworkin RH, Corbin AE, Young JP Jr, et al. Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology. 2003;60:1274-1283.
    • (2003) Neurology , vol.60 , pp. 1274-1283
    • Dworkin, R.H.1    Corbin, A.E.2    Young Jr., J.P.3
  • 90
    • 19444366567 scopus 로고    scopus 로고
    • Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: A pooled analysis of data from randomized clinical trials
    • Gidal BE, Baltes E, Otoul C, Perucca E. Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trials. Epilepsy Res. 2005;64:1-11.
    • (2005) Epilepsy Res , vol.64 , pp. 1-11
    • Gidal, B.E.1    Baltes, E.2    Otoul, C.3    Perucca, E.4
  • 91
    • 0242578835 scopus 로고    scopus 로고
    • Discontinuation of levetiracetam because of behavioral side effects: A case-control study
    • White JR, Walczak TS, Leppik IE, et al. Discontinuation of levetiracetam because of behavioral side effects: a case-control study. Neurology. 2003;61:1218-1221.
    • (2003) Neurology , vol.61 , pp. 1218-1221
    • White, J.R.1    Walczak, T.S.2    Leppik, I.E.3
  • 92
    • 4644370349 scopus 로고    scopus 로고
    • Tolerability of levetiracetam in elderly patients with cognitive disorders, anxiety, and epilepsy
    • Cramer JA, De Rue K, Leppik IE, Kraemer G. Tolerability of levetiracetam in elderly patients with cognitive disorders, anxiety, and epilepsy. Epilepsia. 2003;44(suppl 9):16.
    • (2003) Epilepsia , vol.44 , Issue.SUPPL. 9 , pp. 16
    • Cramer, J.A.1    De Rue, K.2    Leppik, I.E.3    Kraemer, G.4
  • 93
    • 4644308751 scopus 로고    scopus 로고
    • Levetiracetam monotherapy for elderly patients with epilepsy
    • Koopmans SC, Apperson ML, Fariias ST, et al. Levetiracetam monotherapy for elderly patients with epilepsy. Epilepsia. 2003;44(suppl 9):108.
    • (2003) Epilepsia , vol.44 , Issue.SUPPL. 9 , pp. 108
    • Koopmans, S.C.1    Apperson, M.L.2    Fariias, S.T.3
  • 94
    • 4644278220 scopus 로고    scopus 로고
    • Levetiracetam therapy for epilepsy: Use and tolerability in the elderly
    • Werz MA, Lang P, Rienzo T. Levetiracetam therapy for epilepsy: use and tolerability in the elderly. Epilepsia. 2003;44(suppl 9):280.
    • (2003) Epilepsia , vol.44 , Issue.SUPPL. 9 , pp. 280
    • Werz, M.A.1    Lang, P.2    Rienzo, T.3
  • 95
    • 33645975747 scopus 로고    scopus 로고
    • Effects of levetiracetam on stroke-related seizures: An open-label trial: Preliminary report
    • Natale E, Vinci G, Ornella D, Ronnasa TM. Effects of levetiracetam on stroke-related seizures: an open-label trial: preliminary report. Epilepsia. 2004;45(suppl 7):310.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 310
    • Natale, E.1    Vinci, G.2    Ornella, D.3    Ronnasa, T.M.4
  • 96
    • 0028128905 scopus 로고
    • Survey of 260 epileptic patients treated with oxcarbazepine (Trileptal) on a named-patient basis
    • Van Parys JA, Meinardi H. Survey of 260 epileptic patients treated with oxcarbazepine (Trileptal) on a named-patient basis. Epilepsy Res. 1994;19:79-85.
    • (1994) Epilepsy Res , vol.19 , pp. 79-85
    • Van Parys, J.A.1    Meinardi, H.2
  • 97
    • 0037968501 scopus 로고    scopus 로고
    • Safety and tolerability of oxcarbazepine in elderly patients with epilepsy
    • Kutluay E, McCague K, D'Souza J, Beydoun A. Safety and tolerability of oxcarbazepine in elderly patients with epilepsy. Epilepsy Behav. 2003;4:175-180.
    • (2003) Epilepsy Behav , vol.4 , pp. 175-180
    • Kutluay, E.1    McCague, K.2    D'Souza, J.3    Beydoun, A.4
  • 98
    • 0034872572 scopus 로고    scopus 로고
    • Epilepsy in the elderly: The use of tiagabine
    • Pedersen B. Epilepsy in the elderly: the use of tiagabine. Epilepsia. 2001;42(suppl 3):52-54.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 3 , pp. 52-54
    • Pedersen, B.1
  • 99
    • 0346593400 scopus 로고    scopus 로고
    • A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity
    • Bray GA, Hollander P, Klein S, et al. A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity. Obes Res. 2003;11:722-733.
    • (2003) Obes Res , vol.11 , pp. 722-733
    • Bray, G.A.1    Hollander, P.2    Klein, S.3
  • 100
    • 0038516857 scopus 로고    scopus 로고
    • Zonisamide for weight loss in obese adults: A randomized controlled trial
    • Gadde KM, Franciscy DM, Wagner HR 2nd, Krishnan KR. Zonisamide for weight loss in obese adults: a randomized controlled trial. JAMA. 2003;289:1820-1825.
    • (2003) JAMA , vol.289 , pp. 1820-1825
    • Gadde, K.M.1    Franciscy, D.M.2    Wagner II, H.R.3    Krishnan, K.R.4
  • 101
    • 23444443221 scopus 로고    scopus 로고
    • Prevalence of appropriate and problematic antiepileptic combination therapy in older people in the nursing home
    • Harms SL, Eberly LE, Garrard JM, et al. Prevalence of appropriate and problematic antiepileptic combination therapy in older people in the nursing home. J Am Geriatr Soc. 2005;53:1023-1028.
    • (2005) J Am Geriatr Soc , vol.53 , pp. 1023-1028
    • Harms, S.L.1    Eberly, L.E.2    Garrard, J.M.3
  • 102
    • 0345307720 scopus 로고    scopus 로고
    • Rational conversion from antiepileptic polytherapy to monotherapy
    • Baulac M. Rational conversion from antiepileptic polytherapy to monotherapy. Epileptic Disord. 2003;5:125-132.
    • (2003) Epileptic Disord , vol.5 , pp. 125-132
    • Baulac, M.1
  • 103
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med. 2000;342:314-319.
    • (2000) N Engl J Med , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 104
    • 0035160282 scopus 로고    scopus 로고
    • Effectiveness of first antiepileptic drug
    • Kwan P, Brodie MJ. Effectiveness of first antiepileptic drug. Epilepsia. 2001;42:1255-1260.
    • (2001) Epilepsia , vol.42 , pp. 1255-1260
    • Kwan, P.1    Brodie, M.J.2
  • 105
    • 0001836030 scopus 로고    scopus 로고
    • The expert consensus guideline series: Treatment of epilepsy
    • Karceski S, Morrell MJ, Carpenter D. The expert consensus guideline series: treatment of epilepsy. Epilepsy Behav. 2001;2(suppl):A1-A50.
    • (2001) Epilepsy Behav , vol.2 , Issue.SUPPL.
    • Karceski, S.1    Morrell, M.J.2    Carpenter, D.3
  • 106
    • 23644441735 scopus 로고    scopus 로고
    • Treatment of epilepsy in adults: Expert opinion, 2005
    • Karceski S, Morrell MJ, Carpenter D. Treatment of epilepsy in adults: expert opinion, 2005. Epilepsy Behav. 2005;(suppl 1):1-64.
    • (2005) Epilepsy Behav , Issue.SUPPL. 1 , pp. 1-64
    • Karceski, S.1    Morrell, M.J.2    Carpenter, D.3


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