Antiepileptic drug use in nursing home admissions

Annals of Neurology

Volumn 54, Issue 1, 2003, Pages 75-85

  Garrard, Judith ^a,b   Harms, Susan ^a   Hardie, Nancy ^b   Eberly, Lynn E ^a   Nitz, Nicole ^a   Bland, Patricia ^a   Gross, Cynthia R ^b   Leppik, Ilo E ^b,c,d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETHOSUXIMIDE; ETHOTOIN; ETIRACETAM; FELBAMATE; GABAPENTIN; LAMOTRIGINE; MEPHENYTOIN; MESUXIMIDE; METHYLPHENOBARBITAL; OXCARBAZEPINE; PHENOBARBITAL; PHENSUXIMIDE; PHENYTOIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE;

AGED; ANTICONVULSANT THERAPY; ARTICLE; BIPOLAR DEPRESSION; COGNITION; CONTROLLED STUDY; DRUG INDICATION; DRUG UTILIZATION; EPILEPSY; FEMALE; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NURSING HOME; PRIORITY JOURNAL; SEIZURE; UNITED STATES;

AGED; AGED, 80 AND OVER; ANTICONVULSANTS; BIPOLAR DISORDER; COHORT STUDIES; DRUG UTILIZATION; EPILEPSY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MULTIVARIATE ANALYSIS; NURSING HOMES; PATIENT ADMISSION; PREVALENCE; SEVERITY OF ILLNESS INDEX; TIME FACTORS; UNITED STATES;

EID: 0038462269     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10593     Document Type: Article

References (49)

1. Hauser WA. Seizure disorders: the changes with age. Epilepsia 1992;33(suppl 4):S6-S14.
2. Cockerell OC, Eclde I, Goodridge DM, et al. Epilepsy in a population of 6000 re-examined: secular trends in first attendance rates, prevalence, and prognosis. J Neurol Neurosurg Psychiatry 1995;58:570-576.
3. Hauser WA, Annegers JF, Rocca WA. Descriptive epidemiology of epilepsy: contributions of population-based studies from Rochester, Minnesota. Mayo Clin Proc 1996;71:576-586.
4. Wallace H, Shorvon S, Tallis R. Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age-specific fertility rates of women with epilepsy. Lancet 1998;352:1970-1973.
5. Reynolds EH. Early treatment and prognosis of epilepsy. Epilepsia 1987;28:97-106.
6. Cloyd JC, Lackner TE, Leppik IE. Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics. Arch Family Med 1994;3:589-598.
7. Ross EL. The evolving role of antiepileptic drugs in treating neuropathic pain. Neurology 2000;55:S41-S46.
8. Di Trapani G, Mei D, Marra C, et al. Gabapentin in the prophylaxis of migraine: a double-blind randomized placebo-controlled study. Clin Ter 2000;151:145-148.
9. Calabrese J, Bowden C, Sachs G, et al. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry 1999;60:79-88.
10. Harden CL, Lazar LM, Pick LH, et al. A beneficial effect on mood in partial epilepsy patients treated with gabapentin. Epilepsia 1999;40:1129-1134.
11. Gleason RP, Schneider LS. Carbamazepine treatment of agitation in Alzheimer's outpatients refractory to neuroleptics. J Clin Psychiatry 1990;51:115-118.
12. de la Court A, Breteler MM, Meinardi H, et al. Prevalence of epilepsy in the elderly: the Rotterdam Study. Epilepsia 1996; 37:141-147.
13. Rochat P, Hallas J, Gaist D, Friis ML. Antiepileptic drug utilization: a Danish prescription database analysis. Acta Neurol Scand 2001;104:6-11.
14. Moore T, White A. Drug utilization and MDS-based outcomes for elderly nursing home residents - briefing paper. Cambridge, MA: Abt Associates, 1998.
15. Garrard J, Hardie NA, Harms SL, et al. Factors associated with existing and newly initiated antiepileptic drug use in nursing home admissions. Paper presented at: Sixteenth Annual International Conference on Pharmacoepidemiology; 2000; Barcelona, Spain.
16. Tromp AM, Smith JH, Deeg DJ, et al. Predictors for falls and fractures in the Longitudinal Aging Study Amsterdam. J Bone Min Res 1998;13:1932-1939.
17. Aldenkamp AP, Baker GA. The Neurotoxicity Scale. II. Results of a patient-based scale assessing neurotoxicity in patients with epilepsy. Epilepsy Res 1997;27:165-173.
18. Field TS, Gurwitz JH, Avorn J, et al. Risk factors for adverse drug events among nursing home residents. Arch Intern Med 2001;161:1629-1634.
19. Annegers JF, Hauser WA, Lee JR, Rocca WA. Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984. Epilepsia 1995;36:327-333.
20. Lackner TE, Cloyd JC, Thomas LW, Leppik IE. Antiepileptic drug use in nursing home residents: effect of age, gender, and comedication on patterns of use. Epilepsia 1998;39:1083-1087.
21. Garrard J, Cloyd J, Gross C, et al. Factors associated with antiepileptic drug use among elderly nursing home residents. J Gerontol A Biol Sci Med Sci 2000;55:M384-M392.
22. Vickery K. Top nursing facility chains. Provider 2000;26:37-41.
23. Abelson R. Bringing discipline (and scorecards) to nursing homes. New York Times. July 7, 2002:1, 10.
24. Garrard J, Buchanan JL, Ratner ER, et al. Differences between nursing home admissions and residents. J Gerontol 1993;48: S301-S309.
25. Liu K, McBride T, Coughlin T. Risk of entering nursing homes for long versus short stays. Med Care 1994;32:315-327.
26. Spence DA, Wiener JM. Nursing home length of stay patterns: results from the 1985 National Nursing Home Survey. Gerontologist 1990;30:16-20.
27. Fries BE, Schroll M, Hawes C, et al. Approaching cross-national comparisons of nursing home residents. Age Ageing 1997;26(suppl 2):13-18.
28. Rantz MJ, Popejoy L, Mehr DR, et al. Verifying nursing home care quality using Minimum Data Set quality indicators and other quality measures. J Nurs Care Qual 1997;12:54-62.
29. Snowden M, McCormick W, Russo J, et al. Validity and responsiveness of the Minimum Data Set. J Am Geriatr Soc 1999;47:1000-1004.
30. Casten R, Lawton MP, Parmelee PA, Kleban MH. Psychometric characteristics of the minimum data set. I. Confirmatory factor analysis. J Am Geriatr Soc 1998;46:726-735.
31. Lawton MP, Casten R, Parmelee PA, et al. Psychometric characteristics of the Minimum Data Set. II. Validity. J Am Geriatr Soc 1998;46:736-744.
32. Leppik IE. Issues in the treatment of epilepsy. Epilepsia 2001; 42:1-6.
33. Hartmaier SL, Sloane PD, Guess HA, Koch GG. The MDS Cognition Scale: a valid instrument for identifying and staging nursing home residents with dementia using the Minimum Data Set. J Am Geriatr Soc 1994;42:1173-1179.
34. Gruber-Baldini AL, Zimmerman SI, Mortimore E, Magaziner J. The validity of the Minimum Data Set in measuring the cognitive impairment of persons admitted to nursing homes. J Am Geriatr Soc 2000;48:1601-1606.
35. Schachter SC, Cramer GW, Thompson GD, et al. An evaluation of antiepileptic drug therapy in nursing facilities. J Am Geriatr Soc 1998;46:1137-1141.
36. Hauser WA, Annegers JF, Kurland LT. Prevalence of epilepsy in Rochester, Minnesota: 1940-1980. Epilepsia 1991;32:429-445.
37. McElroy SL, Keck PE, Pope HG, Hudson JI. Valproate in the treatment of bipolar disorder: literature review and clinical guidelines. J Clin Psychopharmacol 1992;12(1 Suppl):42S-52S.
38. Chengappa KN, Rathore D, Levine J, et al. Topiramate as add-on treatment for patients with bipolar mania. Bipolar Disord 1999;1:42-53.
39. McElroy SL, Suppes T, Keck PE, et al. Open-label adjunctive topiramate in the treatment of bipolar disorders. Biol Psychiatry 2000;47:1025-1033.
40. Reife R, Pledger G, Wu SC. Topiramate as add-on therapy: pooled analysis of randomized controlled trials in adults. Epilepsia 2000;41(suppl 1):S66-S71.
41. Harms SL, Hardie N, Garrard J, et al. Association of race and geographic region with antiepileptic drug use among elderly nursing home residents. Paper presented at: Annual Meeting of the American Epilepsy Society; 2000; Los Angeles, CA.
42. Neugebauer R, Paik M, Hauser WA, et al. Stressful life events and seizure frequency in patients with epilepsy. Epilepsia 1994; 35:336-343.
43. Krumholz A, Grufferman S, Orr ST, Stern BJ. Seizures and seizure care in an emergency department. Epilepsia 1989;30:175-181.
44. Faught E. Epidemiology and drug treatment of epilepsy in elderly people. Drugs Aging 1999;15:255-269.
45. Hauser WA, Morris ML, Heston LL, Anderson VE. Seizures and myoclonus in patients with Alzheimer's disease. Neurology 1986;36:1226-1230.
46. Thomas RJ. Seizures and epilepsy in the elderly. Arch Intern Med 1997;157:605-617.
47. Neufeld MY, Vishne T, Chistik V, Korczyn AD. Life-long history of injuries related to seizures. Epilepsy Res 1999;34:123-127.
48. Stephen LJ, Brodie MJ. Epilepsy in elderly people. Lancet 2000;355:1441-1446.
49. Buck D, Baker GA, Jacoby A, et al. Patients' experiences of injury as a result of epilepsy. Epilepsia 1997;38:439-444.